جست‌وجوی استاد و پژوهشگر

Jan Johanssonمشاهده پروفایل

استاد

• Biochemistry
• Cell and Molecular Biology
• Neurodegenerative Diseases
• +۳ مورد دیگر

Jan Johansson is a Professor at the Department of Medicine, Huddinge, Karolinska Institutet, specializing in protein biochemistry and translational research. His work focuses on developing novel medical treatments using molecular chaperones for neurodegenerative diseases like Alzheimer’s, spider silk-based biomaterials, and synthetic surfactants for respiratory disorders. He earned his Medical Degree (1990) and PhD (1991) from Karolinska Institutet, with research spanning protein aggregation mechanisms, drug development, and biomedical applications. Education: MD from Karolinska Institutet (1990), PhD in Biochemistry (1991). Research Interests: Molecular chaperones, protein aggregation, Alzheimer’s disease, spider silk biomaterials, synthetic surfactants. Grants: Multiple projects funded by the Swedish Research Council, VINNOVA, and others, including studies on BRICHOS chaperone mechanisms and biomimetic silk production. His lab explores chaperones’ potential to cross the blood-brain barrier, combat amyloid toxicity, and deliver therapeutic agents. Notable contributions include designing synthetic surfactants for neonatal respiratory distress syndrome and elucidating spider silk’s structural basis for toughness. Collaborations with industries and academic institutions drive translational research toward clinical applications.

• Nuclear RNA Interference
• Argonaute Proteins
• Cancer Treatment
• +۳ مورد دیگر

Aishe Sarshad is a researcher at the University of Gothenburg's Institute of Biomedicine and a member of the Wallenberg Center for Molecular and Translational Medicine (WCMTM). Her research focuses on nuclear RNA interference (RNAi) mechanisms, particularly the role of Argonaute proteins in gene regulation and their potential applications in cancer therapy. She earned her PhD from the Karolinska Institute in 2014 and conducted postdoctoral research at the NIH, USA, under Dr. Markus Hafner. Her work explores how nuclear Argonaute-small RNA complexes regulate gene expression in stem cells and cancer cells, aiming to develop novel RNAi-based treatments. Key research interests include understanding nuclear RNAi pathways, viral interactions with host RNAi machinery (e.g., influenza A, SARS-CoV-2), and the role of lamin A in AGO2 localization. Sarshad has received the L’Oréal-UNESCO for Women in Science Award (2019) and collaborates with researchers at the University of Gothenburg, including Carolina Guibentif and Davide Angeletti. She advocates for reproducible science and aims to redefine textbooks by establishing nuclear RNAi as a fundamental biological process. Funding sources include the Swedish Research Council, Knut and Alice Wallenberg Foundation, and others. Her lab (Sarshad Lab) focuses on translational research at the intersection of molecular biology, virology, and cancer biology.

• Breast Cancer
• Cancer Epidemiology
• Molecular Oncology
• +۳ مورد دیگر

Christopher Godina is a Postdoctoral Fellow at Lund University Cancer Center (LUCC) within the Faculty of Medicine at Lund University. His research focuses on cancer epidemiology and radiation, with a specific emphasis on breast cancer biology and molecular mechanisms. Position: Postdoctoral Fellow, Cancer Epidemiology & Radiation Institution: Lund University Cancer Center (LUCC) University: Lund University, Faculty of Medicine Email: christopher.godina@med.lu.se ORCID: 0000-0003-1501-0458 Dr. Godina's expertise spans multiple research areas including Breast Cancer (100%), Caveolin-1 (50%), Patient outcomes (42%), Prospective Cohort Studies (33%), Insulin-Like Growth Factor-Binding Proteins (33%), Therapeutic Procedures (30%), Messenger RNA expression (23%), and Contralateral cancer development (21%). His work contributes to UN Sustainable Development Goal 3: Good Health and Well-being. Analysis of Dr. Godina's publication record reveals a strong focus on molecular biomarkers in breast cancer, particularly examining Caveolin-1 expression patterns, insulin-like growth factor binding proteins (especially IGFBP7), and their clinical implications. His research spans from basic molecular mechanisms to clinical applications, with studies investigating how these biomarkers can improve risk prediction, prognosis, and treatment selection for breast cancer patients. Notably, his work published in Cell on PCSK9 germline variants driving breast cancer metastasis via LRP1 receptor demonstrates significant impact in the field. Highly cited work in Cell (2024) with 11 citation indexes and 28 Mendeley readers Multiple publications in high-impact journals including Carcinogenesis, Scientific Reports, and NPJ Precision Oncology Research focuses on translating molecular findings to clinical applications Dr. Godina actively participates in the Lund University Cancer Centre research community, having presented his work at LUCC meetings. His collaborative research involves multiple investigators at Lund University and potentially international partners, as evidenced by his multi-authored publications across various high-impact journals.

Pedro Ferreiraمشاهده پروفایل

پژوهشگر ارشد

• Computational Biology
• Single-Cell Sequencing
• Spatial Transcriptomics
• +۳ مورد دیگر

Pedro Ferreira is a Digital Futures Postdoctoral Fellow at KTH Royal Institute of Technology, SciLifeLab, and Karolinska Institute (KI) in Stockholm. His research focuses on computational methods for analyzing spatial and single-cell sequencing data from tumors, with an emphasis on reconstructing tumor evolution using cell lineages and trajectories. PhD in Biosystems Science and Engineering from ETH Zürich (2024), supervised by Niko Beerenwinkel and Jack Kuipers. His work bridges computational modeling, statistical analysis, and cancer biology. Key tools include the open-source tumorevo package for simulating tumor evolution under spatial constraints, generating synthetic data for bulk, single-cell, and spatial transcriptomics. Digital Futures Postdoctoral Fellowship Pedro collaborates with Jens Lagergren (KTH, SciLifeLab) and Jonas Frisén (KI) to advance tumor progression research. His software contributions, such as tumorevo , address challenges in modeling clonal dynamics, dispersal rates, and mutation accumulation in spatially structured tumors.

Eva Hedlundمشاهده پروفایل

استاد

• Neurodegenerative diseases
• Selective neuronal vulnerability
• Amyotrophic lateral sclerosis (ALS)
• +۶ مورد دیگر

Eva Hedlund is a Professor of Neurochemistry at Stockholm University's Department of Biochemistry and Biophysics within the Faculty of Science. Her laboratory is situated in Room M 410 at Svante Arrhenius väg 16 in Stockholm. Dr. Hedlund's research focuses on understanding mechanisms of selective neuronal vulnerability and resilience in neurodegenerative diseases, with particular emphasis on amyotrophic lateral sclerosis (ALS). Her work investigates why specific neuron types are selectively vulnerable to neurodegenerative disease processes, despite disease-causing genes often being broadly expressed throughout the nervous system. She develops innovative methodologies including LCM-seq (spatial RNA sequencing at single-cell level) and Axon-seq (for sequencing axonal content) to study disease mechanisms at unprecedented resolution. Analysis of her recent publications reveals a consistent focus on neuronal vulnerability patterns in ALS and Parkinson's disease, with emphasis on developing and applying novel sequencing technologies to study motor neurons at single-cell resolution. Her work bridges fundamental neuroscience with translational approaches, particularly through stem cell models and gene therapy applications. Dr. Hedlund leads an active research group comprising several researchers, postdocs, and PhD students who collaborate on projects related to motor neuron diseases. Her laboratory has established strong expertise in stem cell modeling of neurodegenerative conditions and has developed specialized techniques for analyzing neuronal subpopulations with different vulnerability profiles.

Martin Engeمشاهده پروفایل

دانشیار

• Cancer Stem Cells
• Clonal Evolution
• Single-Cell Multiomics
• +۵ مورد دیگر

Martin Enge is a Senior Researcher and Associate Professor in the Department of Oncology-Pathology at Karolinska Institutet. He holds a Medicine Doctoral degree (2009) from Karolinska Institutet and has been recognized for developing innovative single-cell multiomics methodologies to study cancer biology. Employment: Senior Researcher (2022-), Associate Professor (2023) Location: Bioclinicum v6, Stockholm His research focuses on clonal evolution , gene regulation , and cell interaction in cancer, particularly in pediatric acute lymphoblastic leukemia (ALL) . He investigates how both genetic and epigenetic changes drive tumor progression and response to treatment, using advanced single-cell techniques to distinguish cancer stem cells from stochastic models of tumor growth. His 15 most recent publications span topics including MYC super-enhancer regulation , single-cell transcriptomics in psoriasis , pre-malignant subclones in neuroblastoma , and chromatin interactome in colorectal cancer . These works integrate genomic , transcriptomic , and computational approaches to decode complex disease mechanisms. Scientific Awards: Swedish Childhood Cancer Foundation grant (2021) He leads the research group Cancer stem cells and clonal structure in acute lymphoblastic leukemia at Karolinska Institutet, which has developed novel methods for analyzing functional and genetic errors in individual cells across leukemias and other cancers. His lab is actively involved in understanding pre-leukemic states , relapse mechanisms , and stromal interactions in tumor microenvironments.

• Cancer Research
• Oncology
• Lymphoma
• +۵ مورد دیگر

Georgios Rassidakis is an Adjunct Professor of Pathology at the Department of Oncology-Pathology, Karolinska Institutet in Stockholm, Sweden. He also serves as a senior physician in clinical pathology and cytology at Karolinska University Hospital. His academic and clinical work spans both research and patient care within the field of oncology. Dr. Rassidakis' research primarily focuses on cancer biology with emphasis on lymphoma, breast cancer, and leukemia. His work spans from basic molecular mechanisms to clinical applications, with significant contributions to understanding protein expression patterns, therapeutic targets, and biomarkers in various malignancies. His laboratory investigates critical pathways including SAMHD1, p53-MDM2 interactions, and immune microenvironment dynamics in cancer progression. Analysis of his recent publications (2022-2025) reveals a strong focus on translational cancer research, particularly in lymphoma subtypes, breast cancer biomarkers, and therapeutic strategies targeting molecular pathways. His work frequently involves collaboration with international research teams and participation in clinical trials such as the HEAT-AML trial. The research demonstrates consistent themes of molecular diagnostics, targeted therapy development, and understanding mechanisms of treatment resistance. Dr. Rassidakis has contributed significantly to the field through numerous high-impact publications in journals including Blood, Nature Communications, and Science Immunology. His work has advanced understanding of cancer biology and contributed to potential therapeutic approaches for various malignancies.

Hong Qianمشاهده پروفایل

استاد

• Cancer and Oncology
• Hematology
• Cell Biology
• +۴ مورد دیگر

Hong Qian is a Professor of Molecular Hematology at the Department of Medicine, Huddinge, Karolinska Institutet, Sweden. She leads the Leukemia Niche Group at the Center for Hematology and Regenerative Medicine (HERM). Her research focuses on understanding the role of the hematopoietic niche in myeloid leukemia progression and drug resistance. She holds a Ph.D. in Stem Cell Biology from Lund University (2007) and completed a postdoc at Linköping University (2008–2011). Before becoming a Professor in 2024, she served as an Assistant Professor (2012), Senior Investigator (2016), and Associate Professor (2022). Research interests include leukemia stem cell biology, bone marrow and skin niches, and developing novel therapeutic strategies. Techniques used include flow cytometry, RNA sequencing, and mouse models. Teaching includes advanced courses on cancer stem cells and hematological diagnostics. Key collaborations involve Nordic institutions and international experts in leukemia research. Grants include funding from the Swedish Cancer Society, Swedish Research Council, and Childhood Cancer Fund. The lab has trained numerous students and postdocs, many of whom have pursued academic careers. Notable achievements include identifying skin niches as reservoirs for AML stem cells and discovering CXCL14 as a therapeutic target in CML.

Sebastian Albinssonمشاهده پروفایل

مدرس ارشد

• Vascular Physiology
• Smooth Muscle Biology
• MicroRNA Research
• +۳ مورد دیگر

Sebastian Albinsson is a Senior Lecturer and Molecular Vascular Physiology Researcher at Lund University's Faculty of Medicine. He holds roles as Research Team Manager, Course Director, and Principal Investigator within the EXODIAB: Excellence of Diabetes Research in Sweden initiative. His work contributes to UN Sustainable Development Goals focused on health and well-being. Research Interests: Albinsson specializes in vascular physiology, smooth muscle biology, and the role of microRNAs in cardiovascular disease. His research explores hypertension mechanisms, aneurysm development, and molecular pathways regulating vascular smooth muscle function. Key focuses include YAP/TAZ signaling, actin cytoskeleton dynamics, and transcription factor-driven processes in vascular pathology. Recent Article Trends: Recent work emphasizes genome sequencing in heart failure, YAP/TAZ regulation in vascular mechanotransduction, and microRNA-driven lipid accumulation. These studies highlight translational applications in precision medicine and disease prevention. Grants & Projects: Exploring the relationship between metabolic vascular disease, smooth muscle mechanosensing and vascular ageing (2025–2026) Kan blodkärlens sträcksenor skydda mot aneurysm? (2024–2026) Advising: Supervised 8 research works, focusing on vascular biology and molecular mechanisms. Labs/Teams: Active in EXODIAB and the Molecular Vascular Physiology group, collaborating internationally on cardiovascular and diabetes research.

• Prostate Cancer
• Cancer Epidemiology
• Genetic Epidemiology
• +۴ مورد دیگر

Anna Plym serves as an Assistant Professor at Karolinska Institutet's Department of Medical Epidemiology and Biostatistics since 2022, while maintaining adjunct faculty status at Harvard T.H. Chan School of Public Health and research affiliation at Brigham and Women's Hospital. Her work centers on genetic epidemiology within Fredrik Wiklund's research group, focusing on prostate and testicular cancer risk prediction. Her academic credentials include: PhD in Cancer Epidemiology (Karolinska Institutet, 2019) MSc in Public Health Epidemiology (Karolinska Institutet, 2013) MSc in Biomedical Science (Uppsala University, 2007) Dr. Plym's research pioneers genetic-risk based prevention strategies for prostate cancer, demonstrating that men with high polygenic risk scores face ~50% lifetime prostate cancer risk versus Analysis of her 15 most recent publications (2022-2025) reveals three dominant trends: 1) Development of multi-ancestry polygenic risk scores validated across diverse populations; 2) Investigation of gene-lifestyle interactions for risk compensation; 3) Clinical translation of genetic tools for early detection and prevention. Her work consistently bridges epidemiological discovery with practical clinical applications. Her scientific contributions have been recognized through: 2021 Young Investigator Award (Prostate Cancer Foundation) 2021 Scholar-in-Training Award (American Association for Cancer Research) Dr. Plym's research is supported by substantial institutional funding, including nearly 120 million SEK secured by her department in 2024 Swedish grants and Karolinska Institutet's 254 million SEK award from the Swedish Cancer Society in 2021. She actively mentors trainees and contributes to large-scale initiatives like the Million Veteran Program. Her laboratory work within Fredrik Wiklund's group employs cutting-edge genomic epidemiology approaches, with current projects focusing on integrating MRI with genetic risk scores and developing ethnicity-specific risk prediction tools for global clinical implementation.

• Stem Cell Biology
• Reproductive Medicine
• Estrogen Nuclear Receptors
• +۵ مورد دیگر

Jose Inzunza is a Principal Researcher and Docent (Associate Professor) at the Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden. His academic career spans over two decades, with a focus on stem cell biology , reproductive medicine , and estrogen receptor research . He leads the KISCO unit, specializing in 3D organoid models for disease and drug testing. Education : Ph.D. in Medical Sciences, Karolinska Institutet (2003) Docent in Developmental Biology, Karolinska Institutet (2013) Research Interests include: elucidating the role of MMP-19 and TIM-1 in ovulation using ERβ knockout mice, studying estrogen receptor signaling in stem cell differentiation, somatic cell nuclear transfer for isogenic stem cells, and 3D organoid models for regenerative medicine. His work integrates cell and molecular biology , immunology , and medical genetics . Recent Publications highlight his interdisciplinary approach, spanning Alzheimer's disease (ERβ sex-specific protection), organoid modeling (endometrial responses), structural biology (ZP2-targeted contraception), and neurodevelopment (fluoxetine effects on dopaminergic neurons). Over 40 peer-reviewed articles in journals like PNAS , Nature Biotechnology , and Stem Cells . Teaching & Leadership : Organizer of five doctoral courses in stem cell biology and regenerative medicine, including Embryology I and Gene Regulation . Course leader for The Human Body, Health and Disease at Stockholm University. His team includes senior researchers, postdocs, and molecular biologists. Grants include funding from the Swedish Research Council (2025-2028: integrative structural biology; 2024-2026: ovarian aging) and VINNOVA (2023-2024: organoid-based drug screening).

Sandra Baldaufمشاهده پروفایل

استاد

• Evolutionary Biology
• Genomics
• Phylogenetics
• +۳ مورد دیگر

Sandra Baldauf is a Professor at the Department of Organismal Biology; Systematic Biology at Uppsala University. Her research focuses on evolutionary biology, genomics, and phylogenetics, particularly in understanding eukaryotic origins, microbial diversity, and molecular evolution. She has contributed significantly to studies of slime molds (Dictyostelids), mitochondrial genetics, and the reconstruction of the eukaryote tree of life. Her work bridges genomic analysis with organismal biology, using molecular tools to explore evolutionary relationships and genetic mechanisms across diverse taxa. Key areas include the study of horizontal gene transfer, phylogenetic methodology, and the role of natural products in parasitology. Recent publications highlight her contributions to resolving the eukaryote root, analyzing acaricidal plant oils, and discovering new species of social amoebae. Her research emphasizes interdisciplinary approaches combining fieldwork, genomic sequencing, and computational biology. Awards and grants are not explicitly mentioned in the provided text, though her high citation count and international collaborations suggest significant recognition. She advises students through her research activities, though specific names are not listed here.

Ola Larssonمشاهده پروفایل

پژوهشگر

• Cancer Biology
• Molecular Biology
• Translational Regulation of Gene Expression
• +۳ مورد دیگر

Ola Larsson is a Principal Researcher and Head of the Department of Oncology-Pathology at Karolinska Institutet , Sweden. Since July 2025, he has led this department, focusing on translational control in cancer biology. His research explores how dysregulated mRNA translation drives oncogenesis and tumor microenvironment dynamics. Key Research Themes: mTOR signaling, stress responses, epigenetic regulation, and metabolic adaptation in cancer. Methodological Contributions: Co-developed anota , anota2seq , and NOMAD for translational profiling. Recent Work spans breast cancer mechanotransduction, pancreatic tumor translation programs, and stress-induced reprogramming in neurodevelopmental and metabolic diseases. His Nature (2025) study on the integrated stress response highlights translational plasticity in cancer, while Brain (2025) links TSC2 loss to neurodevelopmental transcript suppression. Collaborative efforts include tumor-stromal interactions in Nature Reviews Cancer (2023) and metabolic control via Cell Metabolism (2022) studies. Leadership includes heading the Department of Oncology-Pathology since 2025 and serving as a Docent at Karolinska Institutet since 2016. His Proceedings of the National Academy of Sciences (2020) work on MNK2 in macrophages and Nature (2013) on TP53 mutations underscore his translational expertise.

Gottfrid Sjödahlمشاهده پروفایل

دانشیار

• Bladder Cancer
• Urothelial Cancer Genomics
• Molecular Subtyping
• +۳ مورد دیگر

Gottfrid Sjödahl is an Associate Professor and Researcher at Lund University Cancer Centre (LUCC), where he leads the Urothelial Cancer Genomics research group. His work bridges clinical urology and molecular oncology, focusing on bladder cancer subtyping and therapeutic innovation. Research interests include: Molecular taxonomy of urothelial cancers Genomic drivers of bladder cancer progression Tumor microenvironment dynamics Immunotherapy response biomarkers Cost-effectiveness of precision oncology approaches His recent publications demonstrate a strong focus on molecular classification systems (LundTax algorithm), tumor plasticity studies across microenvironments, and immune profiling of bladder cancer subtypes. This work integrates computational biology, clinical oncology, and translational research. Active research projects: Principal Investigator: Molecular subtype-dependent biomarkers for systemic treatment of advanced bladder cancer (Cancerfonden, 2023-2025) Co-supervisor: Cellular and molecular cartography of muscle-invasive bladder cancer (Doctoral project, 2019-2025) He contributes to LUCC's urothelial cancer research initiatives and participates in academic events including cancer genomics seminars and research dissemination activities.

• Bioinformatics and Computational Biology
• Computer Graphics and Computer Vision
• Medical Imaging

Kimmo Kartasalo is a Senior Research Specialist and Assistant Professor at the Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Sweden. His research focuses on the intersection of Artificial Intelligence , Bioinformatics , and Medical Imaging , particularly in cancer diagnostics. Current roles: Senior Research Specialist (2024-), Assistant Professor (2024-2030) Supervision: Sol Erika Boman (2023), Kelvin Szolnoky (2022) His work emphasizes deep learning for histopathology analysis, including prostate cancer grading, breast cancer spatial gene expression prediction, and multi-stain whole-slide imaging. He leads projects in 3D tissue reconstruction , virtual reality histology visualization , and AI-assisted diagnostic uncertainty estimation . Collaborations span international institutions and include algorithm benchmarking challenges like PANDA and ACROBAT. Key methodological contributions include physical color calibration for digital pathology scanners, conformal prediction frameworks for diagnostic reliability, and open-source tools like OpenPhi for whole-slide image processing. His publications appear in top journals including Nature Medicine , Cancer Research , and European Urology .