معرفی
Jan Johansson is a Professor at the Department of Medicine, Huddinge, Karolinska Institutet, specializing in protein biochemistry and translational research. His work focuses on developing novel medical treatments using molecular chaperones for neurodegenerative diseases like Alzheimer’s, spider silk-based biomaterials, and synthetic surfactants for respiratory disorders. He earned his Medical Degree (1990) and PhD (1991) from Karolinska Institutet, with research spanning protein aggregation mechanisms, drug development, and biomedical applications.
- Education: MD from Karolinska Institutet (1990), PhD in Biochemistry (1991).
- Research Interests: Molecular chaperones, protein aggregation, Alzheimer’s disease, spider silk biomaterials, synthetic surfactants.
- Grants: Multiple projects funded by the Swedish Research Council, VINNOVA, and others, including studies on BRICHOS chaperone mechanisms and biomimetic silk production.
His lab explores chaperones’ potential to cross the blood-brain barrier, combat amyloid toxicity, and deliver therapeutic agents. Notable contributions include designing synthetic surfactants for neonatal respiratory distress syndrome and elucidating spider silk’s structural basis for toughness. Collaborations with industries and academic institutions drive translational research toward clinical applications.
