جستجوی استاد راهنمای دانشگاهی

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• Biological Physics
• Biophysics
• Theoretical Physics
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Frank L. Brown is a Professor of Chemistry & Biochemistry at the University of California, Santa Barbara, with a joint appointment in Physics and the Biomolecular Sciences & Engineering (BMSE) program. His research focuses on theoretical and computational studies at the interface of physical chemistry and biophysics, particularly biomembrane dynamics and spectroscopy. Dr. Brown received his B.S. in Chemistry and B.A. in Applied Mathematics from UC Berkeley, followed by a Ph.D. in Physical Chemistry from MIT. He has held postdoctoral appointments at UC San Diego and the University of Chicago before joining UCSB in 2001. He is the recipient of prestigious awards including the Alfred P. Sloan Research Fellowship and the Presidential Early Career Award in Science and Engineering. His laboratory employs tools from statistical mechanics, hydrodynamics, and quantum mechanics to study biomembrane structure, dynamics, and interactions with embedded proteins. Key research areas include lipid bilayer fluctuations, membrane protein diffusion, and interpretation of spectroscopic techniques like single-molecule fluorescence and neutron spin echo. Dr. Brown has mentored numerous graduate students and postdoctoral researchers, with notable alumni including Brian Camley, Max Watson, and Golan Bel. His research is supported by grants from agencies such as the National Science Foundation and the Department of Energy. He directs the Brown Research Group, which collaborates with institutions like the CNSI Center for Scientific Computing. His work bridges computational modeling and experimental biophysics, advancing understanding of membrane systems in health and disease.

• Physical Chemistry
• Biophysics
• Biomembranes
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Vikramaditya G. Yadav is an Associate Professor at the University of British Columbia (UBC) in the Department of Chemical and Biological Engineering, Faculty of Applied Science. He directs the Master of Engineering Leadership (MEL) Program in Sustainable Process Engineering and leads the BioFoundry research group. Education: B.A.Sc., University of Waterloo (2007) Ph.D., Massachusetts Institute of Technology (2013) Postdoctoral Associate, Harvard University (2014) His research spans sustainable chemical manufacturing, metabolic engineering, and biotechnology. Key areas include: Designing biosynthetic enzymes for biomass valorization Developing bioremediation strategies for industrial water quality Creating innovative drug delivery systems and tissue engineering solutions Advancing synthetic biology for pharmaceutical and bioenergy applications His recent work focuses on ocular drug delivery, cannabinoid biosynthesis in E. coli, lignin-based nanoparticles for cancer therapy, and computational analysis of plant secondary metabolites. Collaborations with start-ups, industry, and medical labs drive innovation in Canada's bioeconomy. Professional Leadership: Chair, Biotechnology Division of the Chemical Institute of Canada Associate Editor, The Canadian Journal of Chemical Engineering He is affiliated with UBC's BioProducts Institute and contributes to project-based learning pedagogy.

• Biocatalysis
• Bioremediation
• Bioprocess engineering
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Professor Mikko Haataja is a distinguished faculty member in the Department of Mechanical and Aerospace Engineering at Princeton University's School of Engineering and Applied Science. Holding a Ph.D. from McGill University (2003), he leads the Haataja Research Group focused on theoretical and computational approaches to materials science and physical biology. His office is located in D404C Engineering Quadrangle, and he serves as an advisor to numerous graduate students working at the intersection of physics, materials science, and biology. Professor Haataja's research spans multiple domains including theoretical and computational materials science, physics of materials, and physical biology. His work examines microstructure formation during solid-solid phase transformations and solidification, growth of electrodeposited thin films and quantum heterostructures, dynamics of driven interfaces with mobile impurities, recrystallization kinetics, cell signaling mechanisms, and the regulation & self-organization of 'lipid rafts' in plasma membranes. His group has pioneered concepts in 'dynamically programmable electromechanical 2D materials' and investigates phase separation phenomena in biological systems. His publication record demonstrates significant contributions across several key areas: intracellular phase transitions and biomolecular condensates, 2D transition metal dichalcogenide materials, lipid bilayer membrane physics, solid oxide fuel cells and batteries, and organic semiconductor thin films. His most recent work focuses on amyloid-like fibril formation, liquid-liquid phase separation in biological contexts, and defect engineering in 2D materials, reflecting his interdisciplinary approach that bridges physics, materials science, and biology. Professor Haataja actively mentors graduate students and postdoctoral researchers, with numerous co-authored publications indicating strong advising relationships. His research program encompasses multiple funded projects investigating materials for energy conversion and storage, intracellular organization mechanisms, and novel 2D material systems. The Haataja Group maintains strong collaborations with other Princeton researchers and external institutions, particularly in the fields of biophysics and advanced materials. The Haataja Group operates as a dynamic research laboratory employing computational modeling and theoretical approaches to address fundamental questions in materials science and biophysics. Their work spans from atomic-scale simulations to continuum modeling, with particular emphasis on phase-field crystal models, membrane biophysics, and 2D material systems. The group maintains specialized computational infrastructure for multiscale modeling and collaborates extensively with experimental groups to validate theoretical predictions.

• Theoretical and computational materials science
• Physics of materials
• Physical biology
• +۱۳ مورد دیگر

Thomas Michaels is an Assistant Professor at the Department of Biology, ETH Zürich, leading the Michaels Group . His research focuses on theoretical models of biomolecular condensates and protein aggregation in biological systems. Research Themes : Protein aggregation, liquid-liquid phase separation, membrane biophysics, and the role of condensates in neurodegenerative diseases like Alzheimer’s and Parkinson’s. Collaborative Approach : Integrates theoretical physics, control theory, and computational biology with experimental validation to design therapeutic strategies. Recent Publications highlight his work on amyloid formation mechanisms, lipid interactions, and phase-separated compartments as biochemical reactors. His group trains PhD students in systems biology and biocondensate physics.

• Soft Matter Physics
• Living Matter Physics
• Protein Aggregation
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Thibault Mayor is a Professor in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories at the University of British Columbia (Vancouver). His research focuses on understanding how cells manage misfolded proteins, with implications for neurodegenerative diseases like Parkinson's and Alzheimer's. He holds academic affiliations with the Centre for High-Throughput Biology (CHiBi) and has been recognized with awards including the UBC Killam Teaching Award (2020). Education: BSc, University of Geneva, Switzerland (1997) PhD, University of Geneva & Max Planck Institute of Biochemistry, Germany (2001) Postdoctoral Fellow, California Institute of Technology (2002) Research Interests: Mayor's lab investigates protein homeostasis, ubiquitin-proteasome system dynamics, and the molecular mechanisms underlying protein aggregation in aging and disease. Projects include proteomic approaches to identify aggregation-prone proteins and develop microbial cell factories for protein production. Grants & Awards: CIHR Project Grant ($730K, 2018) Michael Smith Foundation Career Award (2012) UBC Killam Teaching Award (2020) Labs & Collaborations: The Mayor Lab is part of the Michael Smith Laboratories and collaborates with computational biologists like Jörg Gsponer. They maintain active partnerships in proteomics and systems biology, contributing to initiatives like the BC Proteomics Network.

• Protein Homeostasis
• Ubiquitin Proteasome System
• Neurodegenerative Diseases
• +۷ مورد دیگر

Shasha Chong is an Assistant Professor of Chemistry at the California Institute of Technology and a Ronald and JoAnne Willens Scholar. She earned her B.S. from the University of Science & Technology of China (2008) and Ph.D. from Harvard University (2014). Her research bridges chemistry, physics, and biology to investigate the molecular mechanisms of cellular processes, focusing on intrinsically disordered regions (IDRs) in transcription proteins. Research Focus: IDRs in transcriptional regulation, cancer biology, liquid-liquid phase separation, and single-molecule imaging techniques. Grants & Awards: CCE Innovation Award (2024), ALSF Innovation Grant, Mallinckrodt Research Grant, Margaret E. Early Medical Research Trust Grant. Collaborations: Caltech-City of Hope Biomedical Research Initiative Grant (2025). Teaching: Co-instructor for courses like Biochemistry Laboratory (Ch 11) and Advanced Topics in Biochemistry (BMB/Bi/Ch 174). Labs & Teams: Leads the Chong Laboratory at Caltech, focusing on interdisciplinary approaches combining single-molecule imaging, genome editing, and bioinformatics.

• Transcriptional Regulation
• Intrinsically Disordered Proteins
• Single-Molecule Biophysics
• +۴ مورد دیگر

David S. Eisenberg is a Professor of Chemistry and Biochemistry and Biological Chemistry at the University of California, Los Angeles, where he also serves as Director of the UCLA-DOE Institute for Genomics and Proteomics and as an HHMI Investigator. His research focuses on protein interactions, particularly the structural basis for conversion of normal proteins to the amyloid state and conversion of prions to the infectious state. Dr. Eisenberg earned his undergraduate degree in biochemical sciences from Harvard College and his D.Phil. degree in theoretical chemistry from Oxford University on a Rhodes Scholarship. His postdoctoral research was on ice and water with Walter Kauzmann at Princeton and in protein crystallography with Richard Dickerson. He joined the UCLA faculty after his postdoctoral studies. Dr. Eisenberg and his research group focus on protein interactions in amyloid and prion diseases. These diseases involve protein aggregation where normal functional proteins convert to abnormal aggregated forms. Systemic amyloid diseases like dialysis-related amyloidosis result from fiber accumulation until organ failure, while neurodegenerative diseases like Alzheimer's, Parkinson's, ALS, and prion conditions appear to be caused by smaller oligomers. In 2005, his team determined the atomic-level structure for the amyloid fiber spine, revealing a 'steric zipper' of two parallel beta sheets packed across a dry interface. Since then, they've determined approximately 90 amyloid spines from 15 disease-related proteins. In 2010, they identified the structure of a toxic amyloid-related oligomer consisting of six anti-parallel beta strands forming a cylindrical barrel. His recent publications demonstrate continued innovation in amyloid research, with focus areas including structural prediction of amyloid formation, mechanisms of tau fibril disassembly in Alzheimer's disease, cryo-EM analysis of amyloid polymorphism, and structure-based design of inhibitors for amyloid toxicity. His work integrates computational, structural, and biochemical approaches to understand protein aggregation across multiple disease contexts. Dr. Eisenberg has received numerous prestigious awards and honors: National Academy of Sciences Member American Philosophical Society Member Institute of Medicine Member Howard Hughes Medical Institute Investigator Biophysical Society Emily M. Gray Award Harvard Westheimer Medal UCLA Seaborg Medal Technion - Israel Institute of Technology Harvey Prize in Human Health As Director of the UCLA-DOE Institute for Genomics and Proteomics and an HHMI Investigator, Dr. Eisenberg leads significant research initiatives in protein structure and aggregation. His laboratory combines X-ray crystallography, bioinformatics, and biochemical techniques to investigate protein interactions, with particular emphasis on amyloid-forming proteins and their role in disease. The Eisenberg Lab, located in Boyer Hall at UCLA, maintains an active research program investigating the structural basis of protein aggregation. The lab continues to build on its landmark discoveries of amyloid structures while exploring new frontiers in understanding protein misfolding diseases and developing potential therapeutic interventions.

• Protein Aggregation
• Amyloid Structures
• Prion Diseases
• +۵ مورد دیگر

Ralph H. Colby serves as Professor of Materials Science and Engineering and Chemical Engineering at Pennsylvania State University's College of Earth and Mineral Sciences, holding the Corning Faculty Fellowship. His research focuses on molecular-level dynamics in complex fluids, particularly polymers, ionomers, and liquid crystalline systems. With over 130 publications and authorship of the textbook Polymer Physics (2003), he directs an active research program examining structure-property relationships in soft matter. B.S. in Materials Science and Engineering, Cornell University (1979) M.S. in Chemical Engineering, Northwestern University (1983) Ph.D. in Chemical Engineering, Northwestern University (1985) Professor Colby's research spans polymer physics, rheology, and materials for energy applications. His group employs mechanical rheology, dielectric spectroscopy, and scattering techniques to investigate ion transport in single-ion conductors for batteries, dynamics of glass-forming liquids, and self-assembly in polyelectrolyte systems. Current work emphasizes structure-property relationships in ionomers, liquid crystalline polymers, and branched architectures. Analysis of recent publications reveals consistent focus on ionomer membranes for energy applications, processing-structure relationships in advanced polymers, and fundamental dynamics of complex fluids. Key trends include increasing integration of computational modeling with experimental characterization, expansion into sustainable materials processing, and growing emphasis on applications in battery technology and biomedical materials. Penn State Faculty Scholar Medal for Outstanding Achievement (2022) Bingham Medal, Society of Rheology (2012) American Chemical Society Fellowship Corning Faculty Fellowship in Materials Science and Engineering Professor Colby leads multiple federally funded projects including NSF's 'Fundamental Studies of Flow-Induced Polymer Crystallization' and DOE's 'Conduction mechanisms and structure of ionomeric single-ion conductors'. His group maintains strong industry partnerships with Corning Incorporated and participates in interdisciplinary initiatives like the Penn State Intercollege Graduate Degree Program in Materials Science and Engineering. Current research includes collaborations on breast cancer adherence interventions in Rwanda and conjugated polymer development for flexible electronics. The Colby Research Group operates specialized facilities for rheological characterization, dielectric spectroscopy, and X-ray scattering at Penn State's Materials Research Institute. The team maintains active collaborations with national laboratories and international research groups, focusing on translating fundamental polymer physics discoveries into practical applications for energy storage and advanced manufacturing.

• Polymer Physics
• Rheology
• Ionomers
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Dan A. Dixon is a Professor and Associate Director of Community Outreach and Engagement at the Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences (UAMS), where his research focuses on post-transcriptional gene regulation mechanisms in cancer pathogenesis. His academic credentials include: Ph.D. from Northwestern University B.A. from Augustana University Dr. Dixon's research centers on RNA-binding proteins (notably HuR and tristetraprolin) and their role in destabilizing oncogenic mRNA networks. His laboratory investigates how dysregulation of these post-transcriptional controllers permits overexpression of tumor-promoting genes involved in proliferation, angiogenesis, and metastasis. Key focus areas include colorectal cancer mechanisms, autophagy regulation via Rab27B, stress granule dynamics in mutant p53 contexts, and extracellular vesicle-mediated tumor microenvironment activation. Analysis of his 2022-2025 publications reveals intensifying work on XPO1 inhibition for colorectal cancer chemoprevention, Rab27B-autophagy axis characterization, and mutant p53 vulnerabilities. His studies consistently employ molecular techniques, mouse models (APC Min/+ ), and translational approaches to identify biomarkers and therapeutic targets. Dr. Dixon maintains active laboratory facilities at WPRCI 947 and 951, directing research that bridges fundamental RNA biology with clinical oncology applications. His leadership in community outreach complements his bench-to-bedside research philosophy.

• Cancer Biology
• Molecular Oncology
• RNA Biology
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Andrew D. White is an Associate Professor of Chemical Engineering at the Hajim School of Engineering & Applied Sciences, University of Rochester. He holds a PhD from the University of Washington (2013). His research focuses on automating scientific discovery through AI, particularly leveraging large language models (LLMs) and deep learning techniques in chemistry. His lab develops agents that integrate literature analysis, hypothesis generation, and experimental design to advance fields like molecular dynamics and drug discovery. Education: PhD in Chemical Engineering, University of Washington, 2013 BS/MS (not explicitly stated in text, inferred from career timeline) Research Interests: Large language models for scientific automation Deep learning applications in chemistry and materials science Molecular dynamics simulations Scientific agents and autonomous systems Publications: His work includes groundbreaking studies on closed-loop AI systems for chemistry, federated learning in molecular property prediction, and multi-agent systems for drug discovery. Recent highlights include the Robin system and ChemCrow tools. Awards: Recipient of the NSF Career Award (2018), NIH Outstanding Investigator Award (2020), and the Curtis Teaching Award (2019). He also advises biotech companies and serves on the National Academy of Sciences' Chemical Sciences Roundtable. Grants & Funding: Supported by DOE, NSF (multiple grants including CBET-1751471), NIH (R35GM137966), and LLNL projects. Collaborates with institutions like Argonne National Lab and Qubit Pharmaceuticals. Labs & Teams: Leads the White Lab at Rochester and co-founded FutureHouse, a nonprofit advancing AI-driven scientific discovery. Supervises a multidisciplinary team of PhD students and postdocs in computational chemistry, AI, and biophysics.

• Large language models
• Deep learning in chemistry
• Molecular dynamics
• +۵ مورد دیگر

Martin Burke is the May and Ving Lee Professor for Chemical Innovation and Professor of Chemistry at the University of Illinois Urbana-Champaign , with additional appointments in Biochemistry, Biomedical & Translational Sciences, and multiple campus institutes including the Beckman Institute and the Carl R. Woese Institute for Genomic Biology. Education B.S. Johns Hopkins University , 1998 Ph.D. Harvard University , 2003 M.D. Harvard Medical School , 2003 Research Interests Burke’s program centers on molecular prosthetics : the design, synthesis and application of small molecules that replicate or replace missing or dysfunctional proteins. His group pioneered iterative cross-coupling (ICC) using MIDA-protected haloboronic acids to automate the construction of complex natural products and function-oriented small molecules. Current projects target ion-channel replacement in cystic fibrosis, iron-transport restoration in anemia, and non-toxic antifungals that overcome drug resistance. Scientific Awards & Honors National Academy of Medicine (2021) AAAS Fellow (2021) ASCI Member (2021) iCON Award (2019) Mukaiyama Award, Japan (2019) ACS Nobel Laureate Award for Graduate Education (2017) Thieme-IUPAC Prize in Synthetic Organic Chemistry (2014) Elias J. Corey Award (2013) Arthur C. Cope Scholar Award (2011) Research Output & Impact Burke has authored >120 peer-reviewed articles, >30 patents, and his work has been cited >20,000 times. High-impact publications in Nature , Science , and Angewandte Chemie have advanced automated synthesis, molecular prosthetics, and cystic fibrosis therapeutics. Laboratory & Training The Burke Laboratories house a multidisciplinary team of graduate students, post-doctoral researchers, and physician-scientists developing next-generation molecular prosthetics. The group is supported by NIH, NSF, private foundations, and industry partnerships aimed at democratizing molecular innovation.

• Organic Chemistry
• Small-Molecule Synthesis
• Molecular Prosthetics
• +۷ مورد دیگر

Dr. Jose Perdomo is a Research Fellow at the Central Clinical School, Sydney Medical School, within the Faculty of Medicine and Health at the University of Sydney. He is based at the Charles Perkins Centre, where his research focuses on endothelial damage, immune complex-driven thrombosis, and platelet formation mechanisms. His work employs techniques such as flow cytometry, microfluidics, and intravital microscopy. Dr. Perdomo holds a PhD from the University of Sydney’s School of Molecular and Microbial Biosciences and received a Vice-Chancellor’s Fellowship. His research has led to two international patents and recognition, including 1st prize in the 2020 China Shenzhen Innovation Competition. His studies explore targeted inhibitors to prevent immune complex formation and thrombosis, with applications in cardiovascular health. His research interests include the interplay between white blood cells, endothelial cells, and platelets, with a focus on desialylation, apoptosis, and NETosis in immune thrombocytopenia. He has contributed to understanding vaccine-induced immune thrombocytopenia and thrombotic complications post-myocardial infarction. His findings have been featured in Nature Communications , Blood Advances , and other high-impact journals. Awards: 1st prize in China Shenzhen Innovation Competition (2020). Labs/Teams: Charles Perkins Centre, University of Sydney. Grants: Vice-Chancellor’s Fellowship (University of Sydney). Media Contributions: Insights into AstraZeneca vaccine-related blood clots featured in The Guardian , SMH , and ABC News.

• Thrombosis
• Hematology
• Immunology
• +۳ مورد دیگر

Dr. Sabine Krabbe is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, Germany, where she leads research on neural circuit mechanisms underlying adaptive learning and state-dependent decision-making. Her work integrates neuroscience, molecular biology, and behavioral approaches to understand how internal states influence behavior and how these processes are disrupted in neurological disorders. Dr. Krabbe's research focuses on the interactions between midbrain circuits of the substantia nigra and ventral tegmental area with their output structures such as the striatum and amygdala. She investigates how these networks integrate internal states with environmental cues to produce appropriate behavioral responses. Her laboratory employs state-of-the-art techniques including deep-brain calcium imaging at single-cell resolution in mice, opto- and pharmacogenetic manipulations, anatomical tracings, and molecular approaches to characterize neural circuit elements in detail. Her recent publications reveal significant insights into amygdala interneuron plasticity during fear learning, brain-wide representational drift in memory consolidation, and the molecular mechanisms underlying Parkinson's disease progression. Her work demonstrates how activity patterns within specific neural circuits change in early stages of neurodegenerative diseases and how this dysfunction contributes to cognitive deficits and emotional disturbances. Dr. Krabbe is actively involved in the neuroscience community, organizing the BonnBrain Conference 2026 and sharing research through social media platforms. She has established herself as an emerging leader in the field of systems neuroscience with a particular focus on the neural basis of emotional states and decision-making processes.

• Neural circuit mechanisms
• Adaptive learning
• State-dependent decision-making
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Prof. Raffaele Mezzenga is a Full Professor at ETH Zürich's Department of Health Sciences and Technology and Head of the Institute of Food, Nutrition, and Health. He earned his master's from Perugia University (Italy) and a PhD in Polymer Physics from EPFL, followed by postdoctoral work at UC Santa Barbara. His career includes roles at the Nestlé Research Center and the University of Fribourg before joining ETH in 2009. His research focuses on self-assembly processes in polymers, biopolymers, and colloidal systems, with applications in environmental remediation, bioplastics, and biomedical materials. Key contributions include pioneering protein-based materials and advancing understanding of amyloid fibrils. Education: Master's, Materials Science & Engineering, Perugia University PhD, Polymer Physics, EPFL Research Interests: Self-assembly, biopolymers, amyloid materials, sustainable technologies, food colloids, and soft condensed matter. Awards: 2011 AOCS Award, 2017 APS Fellowship, and 2013 Biomacromolecules Young Investigator Award. Visiting Roles: Held visiting professorships at Aalto University, RMIT, Monash University, Nanyang Technological University, and others. Labs/Teams: Leads the Institute of Food, Nutrition, and Health at ETH, focusing on interdisciplinary research in food science and biomaterials. His work bridges fundamental science and applied innovation, addressing global challenges in sustainability and health through materials science. Recent projects include creating bioplastics from food waste, developing amyloid-based water purification systems, and advancing targeted drug delivery via lipidic mesophases.

• Self-Assembly Processes
• Biopolymers
• Protein-Based Materials
• +۶ مورد دیگر