جست‌وجوی استاد و پژوهشگر

• Oncology
• Cancer Biology
• Signal Transduction
• +۷ مورد دیگر

Dr. Fred Bertrand is a Professor and Program Director in the Biomedical Sciences Program at the University of Alabama at Birmingham (UAB), School of Health Professions . He also holds joint appointments as Senior Scientist in the UAB School of Medicine and Scientist at the Nutrition Obesity Research Center and Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center. With a career spanning over two decades at UAB, he has served as Acting Program Director , Interim Program Director , and Assistant Dean in the School of Health Professions. PhD in Microbiology (1995) and BS in Biology (1990) Current roles: Professor (P), Senior Scientist (C), Program Director Prior roles: Associate Professor (P/S), Assistant Dean, Acting Program Director Dr. Bertrand's research focuses on Notch signaling , GSK-3 interactions , and PTEN regulation in cancer biology. His work has advanced understanding of epithelial-mesenchymal transition (EMT) , stem cell pathways , and drug resistance mechanisms in colorectal, prostate, and leukemic cancers. He has pioneered interprofessional undergraduate research curricula integrating biomedical sciences and health care management. His recent publications examine Notch-3's role in DNA repair , adipose tissue dysfunction in PCOS , and Smad3 phosphorylation in EMT . These studies highlight his expertise in signaling pathway crosstalk and oncogenic processes . As an educator, he has taught courses in: Clinical Microbiology Biomedical Sciences Literature Cell Biology Honors Research Seminars Responsible Conduct of Research

Jialing Xiangمشاهده پروفایل

استاد

• Molecular Cell Biology
• Signaling Networks
• Programmed Cell Death
• +۴ مورد دیگر

Jialing Xiang is a Professor of Biology at the Lewis College of Science and Letters, Illinois Institute of Technology. Her research focuses on molecular mechanisms underlying human diseases, including programed cell death, signaling pathways, and protein trafficking. She holds an M.D. from Xuzhou Medical University and a Ph.D. from the University of Alabama at Birmingham. Her laboratory investigates pro-apoptotic Bcl-2 family proteins (e.g., Bax and Bad), uncovering novel isoforms like BaxΔ2 that serve as potential cancer therapy biomarkers. Key projects explore cross-talk between apoptotic pathways and inflammation/hormonal responses, aiming to identify therapeutic targets. Recent work emphasizes nanopore-based DNA mutation detection and Ubl4A's role in actin dynamics/insulin signaling. Over 30 peer-reviewed publications highlight her contributions to apoptosis regulation, cancer biology, and signaling networks. Expertise includes molecular cell biology techniques, protein interaction studies, and translational research bridging basic science to clinical applications. Currently leads initiatives in biomarker development and drug sensitivity mechanisms in cancer.

• Bioinformatics
• Molecular Biology
• Cancer Biology
• +۶ مورد دیگر

Alessandro Romanel is an Associate Professor in the Department of Cellular, Computational and Integrative Biology (CIBIO) at the University of Trento. His research focuses on molecular mechanisms of cancer, particularly prostate cancer, leveraging computational biology and bioinformatics approaches. Key areas include genome editing (e.g., CRISPR-CAS9), precision medicine, transcriptomics, and next-generation sequencing technologies. He teaches courses such as Bioinformatics, Molecular Basis of Disease, and Scientific Programming. His work integrates experimental and computational methods to study cancer genetics, somatic mutations, and germline variants. Notable projects involve investigating TRPM8 signaling in tumor vulnerability, EXO5 haplotype impacts on genome stability, and YTHDF paralog roles in tumor progression. He has developed tools like SpikeFlow for ChIP-Seq analysis and contributed to ctDNA detection methods in liquid biopsies. Romanel’s research also addresses translational challenges in oncology, including biomarker discovery and drug resistance mechanisms. Collaborations span computational modeling, clinical trials, and precision medicine applications in metastatic cancers. His expertise bridges basic molecular biology with clinical cancer research, emphasizing systems biology and functional genomics approaches.

Greg Brookeمشاهده پروفایل

مدرس ارشد

• Cancer Biology
• Androgen Receptor Signaling
• Gene Therapy
• +۹ مورد دیگر

Dr Greg Brooke is a Senior Lecturer at the School of Life Sciences, University of Essex, with a research focus on enhancing cancer treatment through understanding therapy resistance and developing novel therapeutics. His interdisciplinary work combines molecular, cellular, and computational methods in prostate and breast cancer research, and he has contributed to virology via studies on antiandrogens in viral infections. BSc Biology, Queen Mary London (2000) PhD in Androgen Receptor Variants in Prostate Cancer Progression, Imperial College London (2005) His research explores: Androgen receptor signaling and its role in cancer progression Therapy resistance mechanisms in prostate and breast cancer Design of DNAzymes for gene therapy Fluorescent biosensors for reactive oxygen species Racial disparities in prostate cancer risk Recent publications highlight his work in cancer metabolism , steroid receptor signaling , and antiviral applications of antiandrogens . Key collaborative projects include industrial partnerships for translational cancer research. Martin Harris Fellowship (Imperial College London) Dr Brooke supervises numerous PhD students in cancer biology and has secured grants from Cancer Research UK, Pancreatic Cancer UK, and Wellcome Trust for projects ranging from nucleosomics to MSC-based cancer therapies . He leads the TRICSS platform for biological interaction analysis and contributes to advanced live imaging facilities.

Antonio Marcoمشاهده پروفایل

مدرس ارشد

• Genetics
• Evolutionary Biology
• Molecular Biology
• +۴ مورد دیگر

Dr. Antonio Marco is a Senior Lecturer in the School of Life Sciences at the University of Essex, where he has held this position since 2020. Previously, he was a Lecturer at Essex (2013–2020) and held research roles at the University of Manchester and Arizona State University. His expertise spans genetics, evolutionary biology, and molecular biology, with a focus on microRNA regulation, cancer biology, and computational approaches to genetic analysis. Dr. Marco holds a Ph.D. in Genetics (University of Valencia, 2007), a B.Sc. in Biological Sciences (University of Valencia, 2002), and a Graduate Diploma in Mathematics (LSE University of London, 2017). His research explores the evolutionary mechanisms of gene regulation, particularly in cancer and developmental processes, leveraging advanced computational methods. His research interests include the functional roles of microRNAs in sex-biased gene expression, the evolution of cancer-related genes, and the application of bioinformatics to study population genetics. He currently advises Mohab Helmy (PhD student) and collaborates with a PostDoc researcher, Andrea Hatlen. Dr. Marco’s publications reflect a strong focus on cancer biology, microRNA dynamics, and evolutionary genetics. Recent work investigates somatic evolution in cancer genes, steroid receptor cross-talk in breast cancer, and computational tools for RNA cleavage analysis. His research bridges experimental and computational approaches, addressing fundamental questions in molecular biology and evolution. He maintains an active presence in academic communities, including a blog on evolutionary biology and genetics (eblogution.wordpress.com), a Google Scholar profile (h-index: not specified), and an ORCID identifier. His work contributes to both basic science and applied fields such as biotechnology and medical research.

Metodi Metodievمشاهده پروفایل

مدرس ارشد

• Cancer Biology
• Proteogenomics
• Signal Transduction
• +۵ مورد دیگر

Dr. Metodi Metodiev is a Senior Lecturer at the School of Life Sciences, Department of Biological Sciences, University of Essex. He has been in this role since October 2011, following previous positions as Lecturer (2004–2011) at the same institution and as Research Assistant Professor (1999–2004) at the University of Illinois at Chicago's Laboratory for Molecular Biology. His research focuses on translational and basic cancer biology, combining computational proteogenomics with experimental techniques to identify diagnostic biomarkers and drug targets. He also uses CRISPR/Cas9 to study molecular mechanisms of signal transduction in cancer, particularly the tumor suppressor SCRIB, integrating these methods into student research projects. Metodi holds a PhD in Biological Sciences from the Bulgarian Academy of Sciences (1994), an MSc in Biology from Sofia University St Kliment Ohridsky (1989), and a Post-graduate certificate in C programming for Bioinformatics from the University of Manchester (2004). His academic support hours are on Fridays from 14:00–16:00. His research interests span cancer biology, proteogenomics, signal transduction pathways, CRISPR/Cas9 gene editing, biomarker discovery, and computational bioinformatics. He explores the molecular basis of tumor progression, particularly in breast and cervical cancers, and investigates microbial proteome dynamics in response to environmental stressors. His work bridges computational models with lab experiments, emphasizing personalized therapy and microbial adaptation mechanisms. His publications reflect a focus on cancer biomarkers, proteomic tools, and microbial physiology. Recent studies highlight advancements in breast cancer prognosis using national registries, cervical cancer progression via ROMO1, and CRISPR-based exploration of tumor suppressors. Earlier work includes proteomic profiling of marine microbes under environmental changes and yeast signaling pathways. Metodi has supervised multiple PhD students, including Dr. Nikos Parisis, Dr. Fahri Hejazi, Dr. Esther Adewuyi, and Dr. Samson Adoki. Current advisees are Mrs. Makarim Al-Zubaidi and Ms. Nosheen Faiz (co-supervised). No specific grants are detailed in the provided texts, but his research is supported through institutional and collaborative efforts. His research group operates within the University of Essex's Life Sciences facilities, continuing work initiated at the University of Illinois at Chicago's Laboratory for Molecular Biology. They integrate computational tools with experimental biology to address translational challenges in cancer therapy and microbial adaptation.

Angela Pineمشاهده پروفایل

مدرس

• Human Papillomavirus (HPV) infections
• HPV-related cancers
• Cervical cancer prevention
• +۱۴ مورد دیگر

Angela Pine is a Lecturer at the School of Life Sciences, University of Essex , specializing in HPV infection dynamics, functional nucleic acids, and biomedical innovation. She combines computational modeling and experimental approaches to develop gene therapies and diagnostic tools. HCPC registered Biomedical Scientist Founder of 10zyme (HPV diagnostic accessibility) Member of HPV Coalition (UK policy roadmap) Research Focus: Persistent HPV infections, DNAzyme efficiency, vaginal microbiome interactions, and mental health impacts of HPV diagnoses. Her work bridges molecular biology with public health, targeting global cancer prevention disparities. Key projects: Diagnostic assays, RNA-cleaving DNAzymes, microbiome analysis, HPV vaccination literacy Patents: Novel gene therapy and nanoparticle delivery system Scientific Awards: Fellow of the Institute of Biomedical Science 2 patents (2023) for prostate cancer therapies Teaching: Leads courses in molecular virology, cell biology, and biomedical science employability. Supervises research projects in HPV diagnostics and nucleic acid therapies.

Ralf Zwackaمشاهده پروفایل

مدرس ارشد

• Cancer Biology
• Stem Cell Research
• Apoptosis
• +۵ مورد دیگر

Dr. Ralf Zwacka is a Senior Lecturer at the University of Essex , School of Life Sciences, with a focus on cancer biology and stem cell research. His career spans multiple institutions, including the University of Galway, University of Ulm, and University of Edinburgh. Education: BSc Biochemistry (University of Manchester), PhD (Open University and Forschungszentrum Karlsruhe), MBA Dr. Zwacka's research centers on mesenchymal stem cells (MSCs) as gene delivery vehicles, apoptosis pathways in cancer, and redox-regulated mechanisms in tumor progression. He investigates how MSCs influence tumor metastasis and how epigenetic regulation (e.g., miRNAs) affects cancer cell death. His publications highlight trends in TRAIL-based therapies , MSC engineering , and apoptosis modulation in pancreatic, prostate, and colorectal cancers. Recent work explores SARS-CoV-2 entry inhibition via antiandrogens like enzalutamide. Grants and Funding: Current projects include Next-Generation Liquid Biopsies for pancreatic and colorectal cancer diagnostics (Pancreatic Cancer UK, Bowel Cancer UK), and a COVID-19 Therapeutics Development grant from the University of Essex. Teaching Responsibilities: Courses in Stem Cell Biology , Molecular Basis of Cancer , and Advanced Research Skills . He supervises PhD and MSc students, including Aleyna Gouney , Serap Gokcen Dogan , and Tianyuan Chu .

Guichun Hanمشاهده پروفایل

استاد

• Physiology
• Pathophysiology
• Cardiovascular Physiology
• +۴ مورد دیگر

Guichun Han, M.D., Ph.D., is a Professor of Physiology at the University of Pikeville. His research focuses on cardiovascular physiology, vascular pharmacology, and estrogen receptor signaling in coronary circulation. He holds a Ph.D. in Biochemistry from Dalian Medical University (China), alongside master's and medical degrees from Chinese institutions. Education: Doctor of Philosophy, Biochemistry, Dalian Medical University, China Master’s Degree, Physiology, Dalian Medical University, China Bachelor of Medicine, Inner Mongolia Medical College, China Research Highlights: Investigates molecular mechanisms of estrogen receptors in vascular remodeling, hypertension, and coronary artery disease. Explores G protein-coupled estrogen receptor (GPER) signaling pathways and their therapeutic potential. His publications span estrogen's effects on insulin sensitivity, GPER-mediated vascular relaxation, and androgen receptor roles in prostate cell proliferation. He teaches Human Physiology, Pathophysiology, and Neurophysiology courses.

Emmet Mc Cormackمشاهده پروفایل

استاد

• Cancer Research
• Molecular Imaging
• Pharmaceutical Drug Development
• +۲ مورد دیگر

Emmet Mc Cormack is a Professor in the Department of Clinical Science at the University of Bergen, specializing in Translational Molecular Imaging in Cancer. His research focuses on preclinical model development, multimodal imaging, and pharmaceutical drug development for cancers including leukemia, ovarian cancer, and pancreatic adenocarcinoma. Research interests span cancer biology, molecular imaging, and targeted drug delivery systems. Key areas include developing bioluminescent orthotopic models, ultrasound-enhanced chemotherapy, nanoparticle-based therapies, and leukemia stem cell mechanisms. Publications demonstrate strong focus on oncology therapeutics, with recent work emphasizing imaging-guided treatments, xenograft models, and molecular mechanisms of drug resistance. Research consistently integrates multimodal imaging techniques with pharmacological interventions. Key projects include SonoCURE (sonoporation-enhanced therapy for pancreatic cancer) and AML-VACCiN (dendritic-cell vaccine therapy for acute myeloid leukemia), funded by Research Council of Norway and EU H2020 programs. Leads the Translational Molecular Imaging in Cancer research group developing advanced preclinical models.

Chiswili Yves Chabuمشاهده پروفایل

دانشیار

• Cell Biology
• Cancer Biology
• Developmental Biology
• +۳ مورد دیگر

Dr. Chiswili Yves Chabu is an Associate Professor of Biological Sciences at the University of Missouri, affiliated with the College of Arts and Science. His research focuses on mechanisms of cell-cell communication in tumor progression and metastasis, particularly using Drosophila models to study tumor-immune interactions and mechanical cues in tumors. He holds an award for excellence in teaching (2022) and has contributed to significant findings in cancer biology and developmental genetics. Education: PhD in Biological Sciences, University of Oregon (2008). Research Interests: Investigates tumor heterogeneity, signaling pathways in tumor microenvironments, and the role of mechanical properties in tumor overgrowth. Key areas include immune-cell interactions in cancer and the regulation of cell polarity in neural stem cells. Recent Research Trends: Recent work emphasizes biomarker development for lung cancer, combined therapies using tumor-targeting bacteria, and single-cell RNA sequencing in pancreatic cancer immunotherapy. Articles highlight interdisciplinary approaches spanning molecular mechanisms and clinical applications. Awards: Assistant Professor of the Year (2022) Best Poster Presentation (2012) AAAS Excellence Awards (2000) Advising/Grants: No listed advisees or grants, though his lab (@LabChabu) actively publishes in high-impact journals. Collaborations focus on cancer biology and developmental pathways. Lab/Team: The Chabu Lab explores tumor biology and microenvironment dynamics using genetic and cellular models, contributing to both basic science and translational research.

Joel Pearsonمشاهده پروفایل

استادیار

• Cancer Biology
• Cancer Therapeutics
• Drug Resistance
• +۷ مورد دیگر

Dr. Joel Pearson is an Assistant Professor in the Department of Pharmacology and Therapeutics at the Max Rady College of Medicine, University of Manitoba, and a Scientist at the Paul Albrechtsen Research Institute CancerCare Manitoba. His research focuses on uncovering fundamental principles of cancer biology to improve treatment strategies, particularly targeting aggressive neural, neuroendocrine, and hematological cancers. He identifies novel therapeutic approaches by studying molecular mechanisms such as YAP/TAZ-TEAD signaling and cellular context influences on oncogenesis. Education: Bachelor of Science in Chemical Biology, Thompson Rivers University (2005) Doctor of Philosophy in Immunology, University of Alberta (2013) Postdoctoral Fellow at Lunenfeld-Tanenbaum Research Institute (2013-2022) Research Interests: Dr. Pearson’s work spans brain cancers , cancer genomics , drug resistance , functional genomics , and neuroendocrine/prostate/lung cancers . He emphasizes context-specific oncogenic pathways and has pioneered YAPOn/YAPOff cancer classifications to guide personalized therapies. Awards: Canadian Cancer Society Emerging Scholar (2023-2028) CIHR Postdoctoral Fellowship (2015-2018) Advising & Grants: He is actively recruiting Master’s and PhD students. His research integrates in vitro and in vivo models to explore vulnerabilities in cancer cell cycles and signaling pathways. Collaborations emphasize translational approaches for clinical impact. Labs/Teams: Based at the Paul Albrechtsen Research Institute, Dr. Pearson leads a multidisciplinary team focused on cancer biology and therapeutic development, leveraging cross-appointments with the University of Manitoba.

Donna Peehlمشاهده پروفایل

استاد

• Prostate Cancer
• Kidney Cancer
• Molecular and Cellular Biology
• +۵ مورد دیگر

Donna Peehl, PhD, is a Professor in the Body Imaging Research Group at the University of California, San Francisco (UCSF), Department of Radiology and Biomedical Imaging. She previously served as Professor Emerita at Stanford University's Department of Urology after 35 years. Her research focuses on developing preclinical models for prostate and kidney cancers, including patient-derived xenografts and tissue slice cultures. Current projects involve testing inhibitors of AXL and IQGAP proteins, investigating glycosylation as an immunotherapy target, and hyperpolarized molecular imaging under an NIH U01 grant. Education: PhD in Molecular, Cellular and Developmental Biology (University of Colorado, Boulder), postdoctoral training at UC Irvine and UCSF. Honors include the 2016 Award for Excellence in Urologic Research from SWIU/SBUR. Research Interests: Prostate/kidney cancer models, metabolic profiling, drug testing, biomarkers, and translational science. Over 200 peer-reviewed articles and editorial roles in scientific journals. Grants: NIH U24CA253377 (Co-PI), NIH U01CA217456 (Co-PI), NIH R01 grants. Collaborations with UCSF and Stanford on co-clinical trials and imaging innovations.

Joan Jorgensenمشاهده پروفایل

استاد

• Reproductive Biology
• Gonad Development
• Sex Differentiation
• +۲ مورد دیگر

Joan Jorgensen is Professor in the Department of Comparative Biosciences at the University of Wisconsin-Madison's School of Veterinary Medicine. Her research investigates the molecular mechanisms governing gonad development, sex differentiation, and reproductive biology. She directs a laboratory focused on understanding how cell-cell interactions and signaling pathways regulate reproductive development and function. Dr. Jorgensen's work examines transcriptional regulation of ovarian follicle formation, fetal Leydig cell steroidogenesis, and the roles of Iroquois homeobox factors in reproductive development. Her research utilizes genetic mouse models, molecular biology techniques, and cellular analysis to uncover fundamental processes in sex determination, gamete maturation, and hormone production. She has made significant contributions to understanding how dysregulation of developmental pathways contributes to reproductive disorders and infertility. Current projects investigate IRX3/5 functions in ovarian reserve establishment and uterine receptivity, and cholesterol metabolism in sex differentiation pathways.

Daria Gaykalovaمشاهده پروفایل

دانشیار

• Cancer Biology
• Epigenetics
• Chromatin Regulation
• +۳ مورد دیگر

Dr. Daria Gaykalova is an Associate Professor at the University of Maryland School of Medicine, specializing in head and neck cancer research. She holds a PhD in Cellular and Molecular Pharmacology from the University of Medicine and Dentistry of New Jersey. Her laboratory investigates: Epigenetic regulation in cancer development HPV-related carcinogenesis mechanisms Chromatin structure and alternative splicing interactions Recent publications leverage radiomics, liquid biopsies, and genomic technologies to develop diagnostic and prognostic tools for head and neck cancers. Her work has identified novel therapeutic targets in treatment-resistant cancers. Research collaborations focus on translating molecular discoveries into clinical applications through the NIH-funded Radiomic Biomarkers program.