جست‌وجوی استاد و پژوهشگر

Zachary Klaseمشاهده پروفایل

دانشیار

• HIV Research
• Molecular Virology
• Epigenetics
• +۴ مورد دیگر

Zachary Klase, PhD, is an Associate Professor in the Department of Pharmacology & Physiology at Drexel University College of Medicine. He previously served as an Associate Professor and Interim Assistant Chair of Biological Sciences at the University of the Sciences. Education: PhD in Microbiology, Immunology, and Tropical Medicine, The George Washington University (2008) BS in Animal Biotechnology, Rutgers University, Cook College (2002) Research Focus: Dr. Klase’s lab investigates molecular neuropathogenesis of HIV-1, epigenetic regulation of transcription, and the role of microRNAs in viral diseases. Key areas include HIV latency mechanisms, benzodiazepine effects on HIV chromatin, and interactions between substance use disorders and HIV neuropathogenesis. Recent Research Trends: His work emphasizes how prescription drugs like benzodiazepines alter HIV latency and chromatin structure, as well as how opioids exacerbate HIV-associated neurodegeneration. The lab also explores CD8+ T-cell control of HIV and innovative approaches to cure HIV via latency reversal and CRISPR technology. Awards & Honors: USciences Founder’s Day Faculty Award of Merit (2019) USciences Million Dollar Grantee (2018) ICAAC Young Investigator Award (2011) Advising & Grants: Dr. Klase mentors several PhD and MS students (e.g., Angel Lin, Zachary Capriotti, Courtney Wallace) and leads projects funded by grants including the 2018 Million Dollar Grantee award. His lab collaborates on initiatives like exosome-based HIV studies and neuroHIV modeling using human brain tissue cultures. Labs/Teams: The Klase Lab is part of Drexel’s Pharmacology & Physiology Department, focusing on HIV transcription, epigenetics, and neurovirology. Current projects include benzodiazepine-driven chromatin changes, Tat protein neurotoxicity, and opioid-HIV interaction mechanisms.

Julio Martin-Garciaمشاهده پروفایل

دانشیار

• HIV-1 Neurotropism
• Cellular Senescence
• MicroRNAs
• +۳ مورد دیگر

Julio Martin-Garcia, PhD, is an Associate Professor in the Department of Microbiology & Immunology at Drexel University College of Medicine. He holds a PhD from Universidad Autónoma de Madrid (1997). His research focuses on HIV-1’s neurotropism, cellular senescence in microglia/macrophages, and the role of microRNAs and Toll-like receptors in HIV pathogenesis. Education: PhD - Universidad Autónoma de Madrid (1997) Research Interests: Dr. Martin-Garcia investigates how HIV-1 adapts to infect the central nervous system (CNS), particularly through macrophage and microglial tropism. His lab studies viral envelope glycoproteins, cellular senescence mechanisms linked to HAND (HIV-Associated Neurocognitive Disorders), and the regulatory roles of microRNAs and TLRs in immune responses. Recent work explores therapeutic interventions targeting microRNA-155 and viral entry inhibitors. Publications: Key contributions include defining brain-derived HIV-1 envelope characteristics, uncovering senescence in microglia during infection, and elucidating TLR-microRNA interactions. His work bridges basic virology with translational strategies to combat HIV neuropathogenesis. Awards & Collaborations: No specific awards listed, but he collaborates with Sonia Navas-Martín on SARS-CoV-2 research, focusing on macrophage responses and anti-viral therapies. Advising & Grants: No explicit student advisees listed. Active in securing grants for HIV and coronavirus research, including studies on cellular senescence and innate immunity modulation. Labs/Teams: Member of Drexel’s Institute for Molecular Medicine & Infectious Disease, contributing to interdisciplinary projects on viral pathogenesis and immune mechanisms.

René S Kahnمشاهده پروفایل

استاد

• Psychiatry
• Neuroscience
• Neuropsychopharmacology
• +۷ مورد دیگر

René S Kahn is the Esther and Joseph Klingenstein Professor and System Chair of Psychiatry at the Icahn School of Medicine at Mount Sinai, leading the Department of Psychiatry and directing the Blau Center. He holds an Honorary Lifetime Professorship at Jilin University and has held prominent roles including Chair of Psychiatry at Utrecht University Hospital in the Netherlands. Education: MD from Rijksuniversiteit Groningen (1979) Residencies in Psychiatry and Neurology at UMC Utrecht and VU University Medical Center Amsterdam Fellowship in Biological Psychiatry at Albert Einstein College of Medicine Research Interests: Dr. Kahn’s work focuses on schizophrenia, particularly cognitive dysfunction as a precursor to psychosis, progressive brain changes, and genetic influences on brain structure. His research bridges clinical and basic neuroscience, emphasizing translational applications in neuropsychopharmacology and genetics. Awards: 2016 Lifetime Achievement Award (Netherlands Psychiatric Association) 2014 ECNP Neuropsychopharmacology Award Member of the Royal Netherlands Academy of Arts and Sciences (2009) Grants & Advising: Principal investigator on NIMH-funded studies (UO1, U24, T32) and former leadership roles in grant review boards (UK, Germany). His work has produced over 1,100 publications, including groundbreaking studies on schizophrenia genetics and brain imaging. Labs/Teams: Leads the Blau Center, integrating clinical and translational research in mental health, and collaborates internationally on initiatives like the Accelerating Medicines Partnership for Schizophrenia.

Alison M Goateمشاهده پروفایل

استاد

• Alzheimer's Disease
• Gene Editing
• Genomics
• +۳ مورد دیگر

Alison M Goate is a **Professor & Chair of the Department of Genetics & Genomic Sciences** at the **Icahn School of Medicine at Mount Sinai**, with additional appointments in **Neuroscience** and **Neurology**. She leads the **Ronald M. Loeb Center for Alzheimer’s Disease** and the **Alzheimer’s Disease Research Center**. Her work focuses on **Alzheimer’s disease (AD)** and **addiction (alcohol use disorder)**, integrating genetic, genomic, and stem cell approaches to identify therapeutic targets. Notable roles include **Jean C. & James W. Crystal Professor**, **Director of the Ronald Loeb Center**, and **Elected Member of the National Academy of Medicine**. **Education**: BSc (Hons) from University of Bristol; DPhil (Oxford University); Postdoctoral research at Eleanor Roosevelt Institute, University College London, and Imperial College London. **Research Interests**: Molecular mechanisms of AD and FTD, genetic risk factors (e.g., SPI1, APOE, MS4A), microglial biology, iPSC-derived models, and shared genetic links between AD and alcoholism. Projects include **FASe Project** (family-based AD genetics), **COGA Study** (genetics of AUD), and **DIAN Genetics Core** (dominant AD mutations). **Awards**: 2023 Piepenbrock-DZNE Prize, 2022 Rainwater Prize, Potamkin Prize (1993), and **Lifetime Achievement Awards** from Alzheimer’s Association (2015). Over 740 publications in top journals like *Alzheimer’s Research & Therapy*, *Cell Reports*, and *Acta Neuropathologica*. **Grants/Leadership**: NIH-funded projects on AD genetics, AUD, and stem cell modeling. Lab members include **Edoardo Marcora**, **Alan Renton**, and 15+ trainees. **Lab Focus**: iPSC-derived microglia/macrophages, organoid models of tauopathies, and drug development targeting PU.1/SPI1 pathways. Collaborations include **Dr. Anne Schaefer** (mouse models), **Slesinger Lab** (GIRK2 in AUD), and **BrainXell** (neural cell production).

Azizul Haqueمشاهده پروفایل

دانشیار

• Cancer Immunology
• Immunotherapy
• Neurodegeneration
• +۵ مورد دیگر

Azizul Haque, PhD, is an Associate Professor in the Department of Pharmacology & Immunology at the Medical University of South Carolina (MUSC) and a member of the Cancer Immunology Program at Hollings Cancer Center. He is also a VA Research Scientist at the Ralph H. Johnson VA Medical Center. His research focuses on cancer immunology, neurodegeneration, and inflammation, particularly in spinal cord injury and Parkinson’s disease. Dr. Haque’s expertise includes antigen processing, calpain inhibition, and neuroprotective therapies. His work is supported by NIH/NCI/NINDS, VA, DoD, and other agencies. Research Interests: Cancer Immunology & Immunotherapy Inflammation & CNS Injury Neuronal Degeneration & Regeneration HLA antigen presentation Calpain inhibition mechanisms Environmental toxin effects (arsenic, manganese) Publications Highlight Trends: Focus on spinal cord injury mechanisms and neuroprotection (enolase inhibition, estrogen therapy) Role of calpain in neurodegenerative diseases (Parkinson’s, multiple sclerosis) Immune modulation in cancer (prostate, melanoma) and autoimmune arthritis Toxicology studies on arsenic/manganese exposure effects Grants & Collaborations: Serves as a grant reviewer for NIH, VA, DoD, and others. Collaborates on projects involving nanoparticle delivery systems, T-cell recognition, and environmental health impacts. Leads studies on therapeutic targets like GILT, HLA class II pathways, and anti-inflammatory strategies. Labs/Teams: Affiliated with Hollings Cancer Center and VA Medical Center research programs, focusing on translational immunology and neurodegenerative disease models.

• HIV Immunopathogenesis
• Autoantibody Biology
• Microbiome-Immune Interactions
• +۴ مورد دیگر

Wei Jiang is a Professor in the Department of Pharmacology & Immunology at the College of Medicine, Medical University of South Carolina. Her research focuses on microbial-immune interactions in HIV disease, autoantibody pathogenesis, and neuroimmunological consequences of substance use. She leads translational studies investigating the impact of oral microbiome dysbiosis on neurocognitive disorders in HIV and Alzheimer’s populations. Holds multiple NIH R01 grants including R01DA059854 (2024-2029) examining drug-mediated immune dysfunction in HIV Recipient of the 2019 Dean’s High Impact Research Award for breakthrough work on Staphylococcus-driven autoimmunity in HIV Co-leads MUSC’s Translational Science Award investigating microbiome-cognition links in neurodegenerative diseases Key research themes include: Microbial translocation mechanisms driving HIV-associated immunopathology B cell dysfunction in immunodeficiency and autoimmunity Neuroinflammatory effects of cannabinoids and cocaine in HIV patients Development of human microglia models for studying NeuroHIV Recent publications highlight discoveries on cannabis-induced β-amyloid elevation, cocaine’s gut-protective paradox, and HIV latency mechanisms involving epigenetic regulators. Current lab activities involve multidisciplinary collaborations with virologists, neuroscientists, and computational biologists to advance precision medicine approaches for immune-related disorders.

• Condensed Matter Physics
• Nanomaterials
• Colloid and Polymer Physics
• +۳ مورد دیگر

Pablo Alfonso Del Pino Gonzalez de la Higu is a Professor in the Department of Particle Physics at the Faculty of Physics, University of Santiago de Compostela. He is affiliated with the Research Center in Biological Chemistry and Molecular Materials (CIQUS) and the Strategic Grouping in Materials (AEMAT), where he leads the Colloid and Polymer Physics Group (GFCP). His primary research area is Condensed Matter Physics, with specialized focus on nanomaterial synthesis, colloidal systems, and polymer physics applied to biomedical challenges. Dr. Del Pino's research explores: Design of stimuli-responsive nanocarriers (light/magnetic) for drug delivery Biomedical applications of metal-organic frameworks (MOFs) and plasmonic nanoparticles Nanoparticle-cell interactions and protein corona dynamics Advanced materials for thrombolytic therapy and neuroinflammation modulation Synthesis protocols for inorganic nanoparticles and hybrid nanocomposites His publication trends (2015–2025) reveal sustained innovation in nanoscale drug delivery systems, particularly light/magnetic-activatable platforms using MOFs and plasmonic hybrids. Recent work emphasizes therapeutic applications for ischemic stroke, cancer, and intracellular delivery, alongside fundamental studies on nanoparticle cytotoxicity and standardization protocols. No awards or supervised students are documented. Research infrastructure includes the GFCP laboratory at CIQUS, focusing on nanoparticle synthesis, colloidal characterization, and cellular interaction studies.

Anca Radulescuمشاهده پروفایل

دانشیار

• Dynamical Systems
• Mathematical Biology
• Neuroscience
• +۳ مورد دیگر

Anca Radulescu is an Associate Professor in the Department of Mathematics at the State University of New York at New Paltz. Her research focuses on dynamical systems, mathematical biology, and complex networks, with applications to neuroscience and epidemiology. She has contributed to understanding phenomena such as fractal geometry in brain networks, synchronization in neural systems, and modeling disease spread dynamics. Her work integrates mathematical modeling with interdisciplinary challenges, including analyzing brain connectivity patterns, exploring glucose metabolism in microglia, and investigating population dynamics in ecological systems. Recent studies also address the impact of vaccination adherence on epidemic models and the role of time delays in neuronal networks. Dr. Radulescu has published extensively on topics like Wilson-Cowan systems, quadratic networks, and fractal geometry. Her research bridges abstract mathematical concepts with real-world applications, particularly in health and biological systems.

Franco Feliciمشاهده پروفایل

استاد

• Immunology
• Vaccine Development
• Bacterial Pathogenesis
• +۷ مورد دیگر

Prof. Franco Felici is a Full Professor in the Department of Biosciences and Territory at the University of Molise. His research focuses on vaccine development, bacterial pathogenesis, and antibody engineering using phage display technology. Key areas include meningococcal antigens, epitope mapping, and peptide mimicry for vaccine design. Research interests emphasize understanding microbial virulence factors, especially in Neisseria meningitidis and Streptococcus pneumoniae. His lab develops novel approaches to identify protective epitopes using genomic libraries and next-generation sequencing. Recent work explores immunosignatures correlating with bactericidal activity and the role of memory in embedded systems for military applications. Publications span 20+ years, highlighting contributions to phage display applications, protein microarrays, and candidacidal antibody engineering. Methodological advancements include PROFILER technology for epitope mapping and lambda phage libraries for antigen discovery.

• Neurodegenerative diseases
• Alzheimer’s disease
• Parkinson’s disease
• +۴ مورد دیگر

Russell is a Professor in the Department of Neurology at the University of California, San Francisco (UCSF) School of Medicine. As a leading neuroscientist, he focuses on neurodegenerative diseases including Alzheimer's, Parkinson's, and Traumatic Brain Injury (TBI). He directs the Neurodegenerative Disease Research Center and leads the Russell Lab, integrating basic research with clinical translation. PhD in Neuroscience from Harvard University (2005) MD from Stanford University School of Medicine (2002) His research investigates neurodegenerative mechanisms using advanced neuroimaging, molecular biology, and computational modeling. Current projects explore tau protein aggregation, blood-brain barrier dysfunction in TBI, and neuroprotective CRISPR-based therapies. Recent publications emphasize machine learning applications in neurodegenerative diagnosis, novel biomarkers for ALS progression, and LRRK2 kinase inhibitors for Parkinson's treatment. Research trends show strong focus on translational medicine bridging basic science and clinical practice. NIH Director’s Pioneer Award (2024) Alzheimer’s Association Zenith Fellow (2023) Directed over $10M in NIH grants, advised 5 PhD students, and collaborates with the Gladstone Institutes. Current grants include a NINDS-funded study on TBI recovery mechanisms and a DoD grant exploring neuroprotection in combat-related injuries. Leads the Neurodegeneration Imaging Core and collaborates with the UCSF Memory and Aging Center. Future work focuses on developing AI-driven diagnostic platforms and gene-editing therapies for neurodegenerative diseases.

Olaf Stuveمشاهده پروفایل

استاد

• Multiple Sclerosis
• Neuroimmunology
• Autoimmunity
• +۵ مورد دیگر

Dr. Olaf Stuve is a tenured Professor in the Department of Neurology at UT Southwestern Medical Center and Head of the MS/Neuroimmunology Section. He is also Chief of Neurology at the Dallas VA Medical Center, where he cares for veterans with multiple sclerosis (MS) and neurological disorders. His research focuses on CNS autoimmunity, blood-brain barrier mechanisms, and experimental therapies for autoimmune diseases. Key contributions include studies on myeloid cells, microglia, and molecular markers of autoimmunity. Dr. Stuve has led numerous clinical trials and has over 300 publications. Education: Medical degree from Free University of Berlin, Ph.D. in Immunology from Maastricht University, postdoctoral training at McGill University and UCSF. Research Interests: MS pathogenesis, immune cell subsets, blood-brain barrier dynamics, translational therapies. His work is supported by grants from NIH, VA, NMSS, and industry partners. Awards include the Doris Duke Clinical Scientist Development Award and recognition in D Magazine's Best Doctors. Dr. Stuve mentors students and clinicians across multiple levels and chairs editorial boards for major journals. Publications span clinical trials, immunology, and neurology, emphasizing therapeutic innovation and MS biomarkers. His lab explores cutting-edge topics like tau protein roles in MS and BTK inhibitor efficacy.

Lu Sunمشاهده پروفایل

استادیار

• Neuroscience
• Neurobiology
• Developmental Biology
• +۵ مورد دیگر

Lu Sun is an Assistant Professor in the Department of Molecular Biology at UT Southwestern Medical Center. He holds a bachelor’s degree in Biological Sciences from Tsinghua University and a Ph.D. in neuroscience from Johns Hopkins University. His research focuses on neuron-glia interactions, particularly in myelination mechanisms and glial cell roles in health and neurological diseases. Sun’s work includes pioneering studies on CNS myelination regulation and oligodendrocyte development. Education: Bachelor’s in Biological Sciences, Tsinghua University Ph.D. in Neuroscience, Johns Hopkins University Research interests emphasize neuron-glia interactions, myelination, and glial cell biology. His lab develops novel toolkits to study these interactions, targeting diseases like multiple sclerosis. Recent projects explore lysosomal quality control pathways and spinal cord injury responses in oligodendrocytes. Key achievements include landmark studies on myelination published in Cell and Neuron , and awards such as the NIH New Innovator Award and Chan Zuckerberg Initiative grant. His work highlights the critical role of glial cells in nervous system function and repair. Scientific awards include the Helen Hay Whitney Fellowship, Klingenstein-Simons Award, and multiple NIH grants. His lab actively investigates myelination dynamics and neurological disorders, with a focus on translational applications.

Sanoji Wijenayakeمشاهده پروفایل

استادیار

• Maternal Obesity
• Bioactive Components in Milk
• Epigenetic Mechanisms
• +۵ مورد دیگر

Sanoji Wijenayake is an Assistant Professor at the University of Winnipeg, affiliated with the Department of Biology within the Richardson College for the Environment and Science Complex. His research focuses on understanding how maternal obesity and lactation influence offspring development through bioactive components in milk, particularly milk-derived exosomes. He employs rodent models, cell culture techniques, and advanced molecular tools to study epigenetic mechanisms, inflammation regulation, and microglial function. Key research interests include maternal obesity's impact on offspring health, the role of milk-derived extracellular vesicles in developmental programming, and stress response pathways in extreme environmental conditions. His lab investigates how maternal factors shape offspring resilience to metabolic and inflammatory challenges. Recent publications highlight the protective effects of milk exosomes against inflammation and oxidative stress, as well as their role in epigenetic regulation. His work bridges basic biology with clinical implications, aiming to translate findings into strategies for mitigating obesity-related health risks in children. Dr. Wijenayake is actively mentoring undergraduate and graduate students, postdoctoral fellows, and oversees the Wijelab research group (www.wijelab.ca). He collaborates widely, with funded graduate positions available in maternal-fetal biology and exosome research.

Andrew Stevensonمشاهده پروفایل

پژوهشگر ارشد

• Epigenetics
• Fibrosis
• Skin Biology
• +۵ مورد دیگر

Andrew Stevenson is a Research Fellow at the School of Biomedical Sciences , The University of Western Australia , affiliated with the Burn Injury Research Unit . His work focuses on epigenetic mechanisms in fibrosis and scar formation, particularly in skin and neurological tissues. Education: BSc (Biochemistry and Molecular Biology, University of Western Australia, 2007), PhD (University of Western Australia, 2015) Projects: WA Near-miss Awards, Next-gen cell therapies for skin regeneration, and collaborations with SUDA Ltd on drug delivery systems. Research interests include: Epigenetic reprogramming of fibroblasts to reverse fibrosis Molecular basis of scar phenotype maintenance Long-term systemic effects of burn injuries Neuro-immune interactions post-burn trauma Genomic and transcriptomic profiling of fibrotic tissues His recent publications analyze: Epigenetic drivers of skin fibrosis (WNT4, FOXF2) Genetic factors in scar vascularization Neurological gene expression changes after minor burns Platelet dysfunction following burn trauma Transcriptome-wide studies of keloid and normotrophic scar fibroblasts Contributions include 12 genomic datasets on methylation profiling and leadership in grants from the Department of Health (Western Australia). Collaborations span fields like Thermal Burn , Wound Healing , and Transcriptomics , with 6 similar profiles identified in biomedical research networks.

• Microglial Biology
• Neurodegenerative Diseases
• Traumatic Brain Injury (TBI)
• +۵ مورد دیگر

Dr. Jenna Ziebell is an Associate Professor at the University of Tasmania's Wicking Dementia Research and Education Centre. She holds a PhD from Monash University and has conducted postdoctoral research at the University of Adelaide, University of Kentucky, and University of Arizona/Phoenix Children’s Hospital. Her research focuses on microglial biology in neurological diseases, particularly Alzheimer’s disease and traumatic brain injury (TBI), with an emphasis on inflammatory mechanisms and their impact on aging and cognitive function. She leads the Microglia and Neurodegeneration Research Team and has pioneered studies on microglial-synapse interactions and microglial priming in neurodegenerative processes. Dr. Ziebell’s educational background includes a Bachelor of Science (Monash University) and a Graduate Certificate in Higher Education (University of Tasmania). She coordinates units in the Bachelor of Dementia Care and Master of Dementia programs, emphasizing neuroscience and immunology education. Her funded projects explore microglial roles in Alzheimer’s, TBI, and obesity-related neurodegeneration, supported by grants from the NHMRC, National Foundation for Medical Research and Innovation, and others. Key research themes include microglial dynamics in synaptic remodelling, neurovascular interactions in Alzheimer’s, and biological sex differences in neuroinflammatory responses. Her team’s work has advanced understanding of microglia-pericyte interactions and the social impact of TBI in vulnerable populations. Dr. Ziebell frequently presents at international neuroscience conferences and collaborates on public health initiatives like the TALK-TBI program to improve TBI awareness in Aboriginal communities.