معرفی
Julio Martin-Garcia, PhD, is an Associate Professor in the Department of Microbiology & Immunology at Drexel University College of Medicine. He holds a PhD from Universidad Autónoma de Madrid (1997). His research focuses on HIV-1’s neurotropism, cellular senescence in microglia/macrophages, and the role of microRNAs and Toll-like receptors in HIV pathogenesis.
Education:
- PhD - Universidad Autónoma de Madrid (1997)
Research Interests:
Dr. Martin-Garcia investigates how HIV-1 adapts to infect the central nervous system (CNS), particularly through macrophage and microglial tropism. His lab studies viral envelope glycoproteins, cellular senescence mechanisms linked to HAND (HIV-Associated Neurocognitive Disorders), and the regulatory roles of microRNAs and TLRs in immune responses. Recent work explores therapeutic interventions targeting microRNA-155 and viral entry inhibitors.
Publications:
Key contributions include defining brain-derived HIV-1 envelope characteristics, uncovering senescence in microglia during infection, and elucidating TLR-microRNA interactions. His work bridges basic virology with translational strategies to combat HIV neuropathogenesis.
Awards & Collaborations:
No specific awards listed, but he collaborates with Sonia Navas-Martín on SARS-CoV-2 research, focusing on macrophage responses and anti-viral therapies.
Advising & Grants:
No explicit student advisees listed. Active in securing grants for HIV and coronavirus research, including studies on cellular senescence and innate immunity modulation.
Labs/Teams:
Member of Drexel’s Institute for Molecular Medicine & Infectious Disease, contributing to interdisciplinary projects on viral pathogenesis and immune mechanisms.
