معرفی
Prasun K. Datta is an Associate Professor in the Department of Microbiology and Immunology at Tulane University's School of Medicine, located in Covington, Louisiana. His research focuses on HIV-1 pathogenesis, neuroinflammation, and the interplay between viral infections and cellular metabolism. He investigates how HIV-1 exploits metabolic pathways in macrophages/microglia to establish latent CNS reservoirs and explores mechanisms linking substance abuse (opioids/cocaine) to neurodegeneration. Recent work includes studies on SARS-CoV-2 neurotropism and long-COVID pathogenesis in non-human primate models.
- Education: BS/MS/PhD in Biological Sciences from Calcutta University
Research Interests: Integrates virology, immunology, and neurobiology to address critical questions in viral neuropathogenesis. Key areas include:
- HIV-1 reservoir persistence in the CNS
- Roles of extracellular vesicles in neuroinflammation
- Metabolic reprogramming in infected macrophages
- Cross-talk between viral proteins and host epigenetic machinery
- Molecular mechanisms of SARS-CoV-2 CNS invasion
Publications highlight translational research across HIV/AIDS, neuroimmunology, and emerging infectious diseases. Over 40 peer-reviewed articles in journals like Nature Communications, Cell Cycle, and Journal of Virology demonstrate sustained contributions to understanding viral-host interactions.
