جست‌وجوی استاد و پژوهشگر

Mart Krupovicمشاهده پروفایل

پژوهشگر

• Virology
• Archaea
• Molecular Evolution
• +۷ مورد دیگر

Mart Krupovic is a researcher at the Institut Pasteur in Paris, France, where he leads projects in the Department of Cell Biology and Virology of Archaea. He serves as Principal Investigator (PI) for multiple research initiatives, including the ANR-ENVIRA and Emergence(s) MEMREMA projects, focusing on archaeal membrane remodeling and virus egress mechanisms. His research interests include archaeal virology, extracellular vesicles, membrane dynamics, structural biology, and viral evolution . His work leverages advanced techniques such as cryo-electron microscopy (cryo-EM), genomics, and biophysical analysis to study extremophilic archaea and their viruses. Recent publications highlight discoveries in viral capsid malleability, DNA-carrying extracellular vesicles, and the structural evolution of archaeal motility appendages. The trends in his recent publications (2022–2025) reflect a strong emphasis on structural characterization of archaeal systems , particularly viral and surface appendage architectures. His work often bridges evolutionary biology and molecular mechanics, revealing deep homologies between archaeal and bacterial systems, and uncovering novel mechanisms in DNA transfer, membrane remodeling, and virus-host coevolution. Scientific Awards: No awards mentioned in the provided text. Advising and Grants: Dr. Krupovic has supervised or collaborated with several PhD students and postdoctoral researchers, including Emmanuelle Quemin, Sofia Medvedeva, and Miguel Gomez-Raya-Vilanova. He leads externally funded projects such as ANR-ENVIRA, ANR-FunVesi, and the Emergence(s) MEMREMA project, indicating active grant support for his research. Labs and Teams: He is a key member of the 'Evolution & Ecology Moléculaire Microbienne' research group at the Institut Pasteur, specifically within the 'Cell Biology and Virology of Archaea' team. His lab employs interdisciplinary approaches combining virology, structural biology, and microbial genomics to study archaeal systems.

Thierry Jolyمشاهده پروفایل

استاد پژوهشی

• Animal Reproduction
• Biotechnology
• Cryopreservation
• +۵ مورد دیگر

Thierry Joly is a Research Professor in Animal Sciences at the School of Agronomy, Food, and Environment. His expertise focuses on animal reproduction biotechnologies, particularly cryopreservation of germ and embryonic cells for preserving animal genetic resources through cryobanks. Current Projects: Leading CRB Anim (Investissement d'Avenir, ANR) to develop advanced cryopreservation protocols. Teaching: Head of the 4th-year Biotechnology module and the DA Breeding, Environment, Health program in 5th year. Research Interests: His work bridges reproductive biology and biotechnology, emphasizing long-term sample quality and biodiversity preservation in animal cells. Article Trends: Recent publications highlight his contributions to cryopreservation techniques for guinea pig embryos and transcriptomic/epigenetic studies in rabbit embryos, aligning with his focus on developmental biology and reproductive biotechnology.

Olivier Dissonمشاهده پروفایل

پژوهشگر

• Microbial pathogenesis
• Host-pathogen interactions
• Listeria monocytogenes
• +۶ مورد دیگر

Olivier Disson is a permanent INSERM research scientist (“Chargé de Recherche 1”), working since 2008 in the G5 “Microorganismes et barrières de l’hôte” unit (INSERM U604) at the Institut Pasteur, Paris, France. He leads the ANR-funded project “Microbial translocation across the intestinal epithelium (Organolist)” and participates in several national and international consortia investigating how Listeria monocytogenes breaches host barriers. Education: Ph.D., Molecular and Cellular Biology, University of Montpellier II, 2004 DEA (Master) Biology & Health Sciences, University of Montpellier II, 2000 Magistère Molecular & Cellular Biology, École Normale Supérieure, Lyon, 1999 Research interests revolve around the cellular and molecular mechanisms that enable the food-borne pathogen Listeria monocytogenes to cross intestinal, placental and blood-brain barriers. Using intestinal organoids, live imaging, genetically-modified mice and comparative genomics, his work has uncovered critical roles for PI3-kinase signaling, InlB-mediated immune evasion, and species-specific invasion proteins in listerial dissemination. Recent publications (2021-2024) highlight emerging themes: differential stress responsiveness shapes virulence heterogeneity , bacterial inhibition of Fas-mediated cell death promotes neuroinvasion , and neonatal susceptibility to meningitis reflects immature barriers and microbiota . These studies integrate genomics, cell biology and in vivo infection models to illuminate both pathogen and host determinants of disease. Labs & Teams: Disson works within the Institut Pasteur G5 unit headed by Prof. Marc Lecuit, where he co-supervises post-doctoral fellows, PhD students and engineers on projects funded by ANR, ERC and Swiss National Science Foundation.

• Endocrinology
• Reproductive Biology
• Ecotoxicology
• +۳ مورد دیگر

Céline Boulangé-Lecomte is a full-time Researcher at the UMR-I 02 SEBIO (Environmental Stress and BIOmonitoring of aquatic environments) unit, affiliated with the University of Le Havre Normandy. She holds authorization to direct research (HDR) and serves as Deputy Director/ Director of the SEBIO laboratory. Her research focuses on environmental pollutants, particularly endocrine disruptors, in crustaceans like copepods and shrimps. Key areas include: Physiological impacts on reproduction, development, and behavior Biomarker development and bioassays Transcriptomic approaches to subindividual responses Organismal plasticity and adaptability assessment SEBIO operates at two main sites: the Biology building on the University of Le Havre campus and the Moulin de la Housse Campus at the University of Reims Champagne-Ardenne.

Yashraj Chavhanمشاهده پروفایل

استادیار

• Evolutionary Biology
• Asexual Evolution
• Multicellularity Evolution
• +۴ مورد دیگر

Yashraj Chavhan is an Assistant Professor at the School of Biology , Indian Institute of Science Education and Research Thiruvananthapuram. His research focuses on evolutionary biology of asexual organisms through experimental evolution, genomics, and transcriptomics using bacterial and bacteriophage models. Wenner-Gren Postdoctoral Fellow PhD from IISER Pune Masters in Biotechnology from IBB Pune Research Themes: Origin and evolution of multicellularity Cell differentiation in nascent lineages Phenotypic plasticity in ecological coexistence Complex adaptation in asexual populations Scientific Awards: Wenner-Gren Postdoctoral Fellowship Teaching: Courses in evolution, population genetics, and ecology. Funding: Supported by Anusandhan National Research Foundation (ANRF) and IISER TVM.

• Energy metabolism
• Cellular adaptation mechanisms
• Environmental factors
• +۴ مورد دیگر

Laurence Murillo is a Lecturer at the University of La Rochelle, attached to the AMARE research team and affiliated with the INEE institute. His academic rank corresponds to Lecturer in the CNU 65 research section. His primary research interests include energy metabolism, cellular adaptation mechanisms, environmental factors, pesticides, and marine organisms. His publications focus on environmental impacts on marine species, pesticide neurotoxicity, metabolomics, and ion channel regulation. Recent studies explore AI applications in port ecosystem monitoring, metal contamination effects on bivalves, and pesticide synergy mechanisms. As coordinator of supervised projects since 2015, he mentors students including DUT intern T. Maunier. His research spans coastal ecology, neurotoxicology, and molecular biology, with no scientific awards mentioned in the provided texts.

Claire Maudet-Crépinمشاهده پروفایل

پژوهشگر

• Microbiology
• Infectious Diseases
• Immunology
• +۵ مورد دیگر

Claire Maudet-Crépin is a permanent researcher at the Institut Pasteur in Paris, France, where she works in the Biology of Infection Unit. She has held this position since 2022, following several years as a postdoctoral fellow at the same institution. Her research primarily focuses on host-pathogen interactions, particularly with bacterial pathogens like Listeria monocytogenes and Salmonella. Dr. Maudet-Crépin earned her PhD at the Cochin Institute, Université Paris Diderot, under Dr. Florence Margottin-Goguet, with her thesis defended in December 2011. She previously completed a Master of BioSciences with specialty in Molecular and Cellular Biology at École Normale Supérieure de Lyon, where she ranked 39th out of over 1000 candidates in the competitive admission exam. Her research spans microbiology, infectious diseases, and immunology, with particular expertise in how microRNAs mediate host-pathogen interactions. She has made significant contributions to understanding bacterial invasion mechanisms and immune evasion strategies, especially regarding Listeria monocytogenes. Her work bridges molecular biology with clinical implications, investigating why elderly individuals show increased susceptibility to listeriosis. Analysis of her publication record reveals a progression from early HIV molecular biology research to current focus on bacterial pathogenesis. Her most impactful work includes the 2014 Nature Communications paper that identified the miR-15 microRNA family as cellular restriction factors against Salmonella infection, which earned her the SFBBM Article of the Month prize. Her recent publications demonstrate sophisticated approaches combining comparative genomics, transcriptomics, and in vivo models to investigate host-pathogen dynamics. Article of the month prize by French Society of Biochemistry and Molecular Biology (SFBBM) in December 2014 Dr. Maudet-Crépin has supervised multiple students throughout her career, including M2 students and Master's students in the Biology of Infection Unit. She has contributed to teaching through EMBO practical courses on non-coding RNA in infection and served as a teaching assistant at Pierre & Marie Curie University. As Principal Investigator for the project "Deciphering the age-dependent susceptibility to Listeria monocytogenes," she leads research examining the immunological basis for increased listeriosis risk in elderly populations, with important public health implications given listeriosis's 30% fatality rate.

• Environmental Cardiology
• Cardiovascular Toxicology
• Vascular Biology
• +۴ مورد دیگر

Dr. Jesus A. Araujo serves as Associate Professor of Medicine in the Cardiology Division at UCLA's David Geffen School of Medicine, where he directs the Environmental Cardiology program and holds membership in the Cancer and Stem Cell Biology research area. Board-certified in Internal Medicine and Echocardiography, he provides clinical care at Ronald Reagan UCLA Medical Center with fluency in English and Spanish. His educational trajectory includes: MD from Universidad Central de Venezuela (1991) MS in Molecular Biology from Venezuelan Institute for Scientific Research (1994) PhD in Molecular Biology from UCLA Molecular Biology Institute (2004) Internal Medicine Residency/Internship at Beth Israel Medical Center (1994-1998) Cardiovascular Disease Fellowship at UCLA School of Medicine (1998-2003) Dr. Araujo's Environmental Cardiology and Vascular Biology Laboratory pioneers research at the intersection of environmental exposures and cardiovascular pathophysiology. His work employs genetic, biochemical, and translational approaches to dissect: Mechanisms linking air particulate matter (especially ultrafine particles) to accelerated atherosclerosis Synergistic interactions between pollutant chemicals and oxidized lipids in endothelial inflammation Protective roles of heme oxygenase-1 (HO-1) and Nrf2 pathways against vascular oxidative stress Emerging connections between air pollution-induced lung inflammation and systemic DNA damage with oncogenic potential Publication analysis reveals consistent focus on environmental cardiology with methodological integration of genomics, toxicology, and vascular biology. Key themes include dysfunctional HDL formation from pollutant exposure and HO-1's dual role in transplant rejection and atheroprotection. His contributions earned recognition highlighted in UCLA Health media coverage for elucidating air pollution's cardiovascular impacts. As Environmental Cardiology Director, Dr. Araujo leads collaborative initiatives spanning cardiology, environmental health sciences, and oncology, with laboratory investigations informing public health responses to urban air quality challenges.

Etienne Kornobisمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Evolutionary Biology
• Transcriptomics
• +۸ مورد دیگر

Etienne Kornobis is a bioinformatician and researcher at the Institut Pasteur , affiliated with the Bioinformatics and Biostatistics Hub . He obtained his PhD in Biology from the University of Reykjavik in 2011 and has held postdoctoral positions in Spain before joining the Institut Pasteur in 2016. He became a member of the Bioinformatics and Biostatistics Hub in 2018, where he continues his work on transcriptomics and bioinformatics methodology. His research interests include bioinformatics, evolutionary biology, transcriptomics, population genetics, RNA splicing, genome analysis, reproducible research, workflow development, long-read sequencing, alternative splicing, and microbial genomics . His work emphasizes computational methods for analyzing complex biological data, particularly in non-model organisms and microbial systems. The recent publications of Etienne Kornobis span a broad range of topics in genomics and molecular biology, with a strong trend toward transcriptomic analysis, host-pathogen interactions, microbial genomics, and methodological development in bioinformatics . His work frequently involves high-throughput sequencing, alternative splicing, and data reproducibility, reflecting his expertise in computational biology and systems-level analysis. Scientific Awards: No awards mentioned in the provided text. Etienne Kornobis is actively involved in research mentoring and collaborative projects. He leads the Bioconda project and contributes to Bioconvert , both critical tools for bioinformatics software distribution and data format conversion. He has also taught courses on reproducible data analysis and Software Carpentry , indicating a strong commitment to training and open science. There is no mention of formal student advising or grant leadership in the text provided. Labs and Teams: Bioinformatics and Biostatistics Hub (current) Revive Consortium (past) Epigenetic Regulation unit (past) Expertise group: SysBio – Systems Bioinformatics (past) Biomics – Dry-Lab (past)

Natalia Pietrosemoliمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Biostatistics
• Genomics
• +۶ مورد دیگر

Natalia Pietrosemoli is a Senior Bioinformatician at the Center for Bioinformatics, Biostatistics and Integrative Biology (C3BI) at Institut Pasteur in Paris, where she has been working since November 2015. She specializes in functional and pathway analysis at the genomic level, with expertise in integrative analysis of different omics data both at large-scale and for small datasets. Her work focuses on decreasing the complexity of biological systems by grouping genes and proteins into the pathways they are involved in to increase comprehension of these systems. Her research interests span bioinformatics, biostatistics, genomics, transcriptomics, systems biology, functional genomics, pathway analysis, and omics data integration. She has developed several bioinformatics tools including g-RITA (Gene Set Enrichment Analysis visualization), Sherpa (Transcriptomic Analysis tool), and coGSEA (Comparative Gene Set Enrichment Analysis tool). Her recent publications (2023-2025) demonstrate expertise in viral pathogenesis (particularly Lassa virus and SARS-CoV-2), bacterial biofilms (Leptospira), immunology, and bioinformatics methodology development. She actively participates in teaching and training programs, including the Bioinformatics program for PhD students at Institut Pasteur and the PHINDaccess courses in Comparative Genomics and Functional OMICs. She has collaborated on numerous interdisciplinary research projects, often working with experimental colleagues to provide bioinformatics support and insights. PhD in Computational Biology from Rice University's School of Bioengineering Postdoctoral fellowship at the Swiss Institute of Bioinformatics' Bioinformatics Core Facility Visiting scholar positions at the National Centre for Biotechnology (CNB-CSIC) and Spanish National Cancer Centre Master's degree in Modeling and Simulation of Complex Realities from ICTP and SISSA Dr. Pietrosemoli leads the PHINDaccess twinning initiative with the Institut Pasteur de Tunis and serves as Principal Investigator for several software development projects including g-RITA, Sherpa, and coGSEA. Her work bridges computational analysis with experimental biology, providing critical insights into complex biological systems through sophisticated bioinformatics approaches.

David Siaussatمشاهده پروفایل

دانشیار

• Agroecology
• Molecular biology
• Climate change
• +۸ مورد دیگر

David Siaussat is an Associate Professor at Sorbonne University, affiliated with the Paris Institute of Ecology and Environmental Sciences (iEES Paris). He serves as Team Leader of the Chemo-reception and Adaptation Team (CReA) within the Sensory Ecology Department (EcoSens) and is co-leader of a Master's course in Ecophysiology and Ecotoxicology. His educational background includes: 2017: Habilitation à diriger les recherches from Université Pierre et Marie Curie 2004: Doctorate in Life Sciences, specializing in Diversity of Life from Université Pierre et Marie Curie 2001: Advanced Study Diploma (DEA) in Integrated Invertebrate Biology from Université Pierre et Marie Curie 2000: Master's Degree in Cell Biology and Physiology from University of Versailles-Saint Quentin Dr. Siaussat's research focuses on understanding the impact of anthropogenic pollutants on insects, with particular emphasis on the olfactory system and behavior. His work examines pollutants such as phytosanitary products (insecticides, herbicides), heavy metals (cadmium, selenium, etc.) and endocrine disruptors (bisphenol A, phthalates, etc.). He studies sublethal doses, cocktail effects and interactions with abiotic parameters like temperature. He also leads biocontrol research programs aimed at developing sustainable solutions against crop pests. His research interests span Agroecology, Molecular biology, Climate change, Chemoreception, Development, EcoHealth, Environmental pollution and Insect chemical ecology. His recent publications reveal a strong focus on the interactions between environmental stressors (particularly temperature variations) and chemical pollutants in insect models. His work often employs the moth Spodoptera littoralis as a model organism to study transgenerational effects, pesticide sensitivity, and physiological adaptations. Dr. Siaussat has served in several editorial roles, including as Editor of the "Insect" Journal (2020) and Thematic Editor of "The Canadian Entomologist" (2015). He has held various leadership positions including: 2021: Coordinator of the Biodiversity and Sustainable Development Flagship of the European Alliance 4EU+ 2019: CNRS representative in the national biocontrol consortium 2017-2021: Elected member of the Council of the Faculty of Science and Engineering at Sorbonne University 2017-2020: Director of the Natincontrol Joint Laboratory (ANR Labcom) 2014: Head of the Chemo-Reception and Adaptation Team at iEES Paris Dr. Siaussat leads the Chemo-reception and Adaptation Team (CReA) within the Sensory Ecology Department (EcoSens) at the Paris Institute of Ecology and Environmental Sciences. His laboratory focuses on understanding how environmental pollutants affect insect sensory systems and behavior, with applications in sustainable pest management.

Felipe Moreiraمشاهده پروفایل

استاد مهمان

• Systematic Entomology
• Phylogeny
• Taxonomy
• +۳ مورد دیگر

Felipe Moreira is a Visiting Professor at ENS de Lyon's Institute of Functional Genomics (IGFL) from August 2023 to August 2024. He is a public health technologist, head of the Entomology Laboratory, and coordinator of the postgraduate program in Biodiversity and Health at Brazil's Oswaldo Cruz Institute. His primary focus is systematic entomology, particularly phylogeny and taxonomy of aquatic/semi-aquatic bugs (Hemiptera: Heteroptera). Dr. Moreira holds a PhD from Federal University of Rio de Janeiro (2014) under Jorge Luiz Nessimian. His research emphasizes Gerromorpha and Nepomorpha insects, with contributions to describing new taxa and analyzing biodiversity conservation challenges in Brazil. During his visit to Lyon, he collaborates with Dr. Abderrahman Khila’s team on three key projects: phylogenetic studies of Rhagovelia, molecular experimental techniques training, and academic engagement through seminars. His work bridges systematic entomology with evolutionary genomics, aiming to establish experimental models for future studies in Brazil. His publications span molecular phylogenetics, taxonomic descriptions, and conservation biology, reflecting expertise in arthropod systematics and adaptive evolution.

• Immunology
• Genetics
• Population Genetics
• +۳ مورد دیگر

Darragh Duffy and Lluis Quintana-Murci are core researchers at Institut Pasteur , leading the LabEx Milieu Intérieur consortium. Duffy specializes in translational immunology and standardized immune phenotyping, while Quintana-Murci focuses on human evolutionary genetics and population-scale immune variation. Their collaborative work integrates genetic, epigenetic, and environmental factors to define the boundaries of healthy immune responses. Key Projects: 1000-donor cohort studies, systems immunology frameworks, microbiome-immunity interplay Methodologies: TruCulture stimulation systems, spectral cytometry protocols, multi-omics integration Their research has produced seminal works on TLR pathway dynamics , IFNγ regulation , and HLA-disease associations , with applications in vaccinology , autoimmune disease and infectious immunity . The Milieu Intérieur project, funded under France's Investissements d'Avenir program, serves as a foundational resource for precision immunology and population health initiatives. Scientific Contributions include: Defining genetic/epigenetic drivers of immune variability Establishing standardized protocols for whole-blood immunophenotyping Revealing microbiome-immunity regulatory networks Characterizing age-, sex-, and genetics-based immune response boundaries Their work underpins 70+ research projects globally, with applications in epidemiology , biomarker discovery , and personalized medicine . The consortium maintains strict data governance through its Data Access Committee , ensuring ethical use of participant data.

• Immunology
• Translational Immunology
• Innate Immunity
• +۱۲ مورد دیگر

Darragh Duffy is a Researcher in the Department of Genomes and Genetics at the Institut Pasteur in Paris, where he leads the Translational Immunology group focused on the Milieu Intérieur project. His work centers on understanding interindividual differences in immune responses through population immunology, cellular models, and clinical studies. He is deeply involved in research on innate and adaptive immunity, cytokine signaling, and immune biomarkers in autoimmune and infectious diseases. The Milieu Intérieur project, which he coordinates, aims to define the range of immune variation in healthy populations and apply this knowledge to clinical immunology. His research integrates transcriptomics, systems immunology, and clinical data to uncover mechanisms of immune dysregulation in conditions such as dermatomyositis, systemic sclerosis, and HIV. He collaborates extensively with clinical and genetic research teams, including those led by Lluis Quintana-Murci. His recent publications (2022–2025) reveal a strong focus on interferon pathways, autoantibodies against cytokines, and the impact of aging, sex, and lifestyle on immune function. These studies employ advanced techniques such as single-molecule array (SIMOA) assays and single-cell RNA sequencing. The research has significant implications for biomarker discovery and personalized treatment strategies in autoimmune diseases. Darragh Duffy has mentored numerous PhD students, postdoctoral fellows, and research engineers, indicating an active and expanding research group. His leadership in the LabEx Milieu Intérieur underscores his role in large-scale collaborative science. There is no mention of awards in the provided text, but his publication record in high-impact journals such as Science Advances , The Lancet Neurology , and Journal of Experimental Medicine reflects significant scientific contributions. He has not been described as part-time, retired, or deceased, and remains an active principal investigator at the Institut Pasteur.

Florian Mullerمشاهده پروفایل

پژوهشگر

• Bioimage Analysis
• Single-RNA Imaging
• Spatial Transcriptomics
• +۷ مورد دیگر

Florian Muller is a Group Leader and Researcher at the Photonic BioImaging (UTechS PBI) , Pasteur Institute, Paris. His work integrates advanced microscopy, image analysis, and single-RNA imaging to study spatial transcriptomics and gene regulation. Institution: Pasteur Institute Department: Photonic BioImaging (UTechS PBI) Role: Group Leader (Principal Investigator) His research focuses on quantitative imaging , spatial transcriptomics , and bioimage analysis , with an emphasis on developing computational tools for cell segmentation and RNA localization. He leads projects such as Fish&Chips and autoFISH , and develops open-source software including RNA2seg and Comseg . The recent publications highlight a strong trend in machine learning for image analysis , spatial omics , and high-throughput RNA imaging , particularly using smFISH and point cloud methods. His work bridges biology, computer science, and microscopy. He mentors a team including a PhD student and post-doctoral researchers, contributing to training and collaborative science at the Pasteur Institute.