معرفی
Mart Krupovic is a researcher at the Institut Pasteur in Paris, France, where he leads projects in the Department of Cell Biology and Virology of Archaea. He serves as Principal Investigator (PI) for multiple research initiatives, including the ANR-ENVIRA and Emergence(s) MEMREMA projects, focusing on archaeal membrane remodeling and virus egress mechanisms.
His research interests include archaeal virology, extracellular vesicles, membrane dynamics, structural biology, and viral evolution. His work leverages advanced techniques such as cryo-electron microscopy (cryo-EM), genomics, and biophysical analysis to study extremophilic archaea and their viruses. Recent publications highlight discoveries in viral capsid malleability, DNA-carrying extracellular vesicles, and the structural evolution of archaeal motility appendages.
The trends in his recent publications (2022–2025) reflect a strong emphasis on structural characterization of archaeal systems, particularly viral and surface appendage architectures. His work often bridges evolutionary biology and molecular mechanics, revealing deep homologies between archaeal and bacterial systems, and uncovering novel mechanisms in DNA transfer, membrane remodeling, and virus-host coevolution.
Scientific Awards:
- No awards mentioned in the provided text.
Advising and Grants: Dr. Krupovic has supervised or collaborated with several PhD students and postdoctoral researchers, including Emmanuelle Quemin, Sofia Medvedeva, and Miguel Gomez-Raya-Vilanova. He leads externally funded projects such as ANR-ENVIRA, ANR-FunVesi, and the Emergence(s) MEMREMA project, indicating active grant support for his research.
Labs and Teams: He is a key member of the 'Evolution & Ecology Moléculaire Microbienne' research group at the Institut Pasteur, specifically within the 'Cell Biology and Virology of Archaea' team. His lab employs interdisciplinary approaches combining virology, structural biology, and microbial genomics to study archaeal systems.
