جستجوی استاد راهنمای دانشگاهی

Robert Robersonمشاهده پروفایل

دانشیار

• Cell Biology
• Mycology
• Fungal Morphogenesis
• +۳ مورد دیگر

Robert Roberson is an Associate Professor in the School of Life Sciences at Arizona State University (ASU), specializing in the Cellular and Molecular Biosciences department. He holds a Ph.D. in Plant Biology from the University of Georgia (1989) and an M.Sc. from Stephen F. Austin State University. His research focuses on cytoplasmic order and dynamics in fungal hyphal cells, utilizing advanced bioimaging techniques such as cryo-electron microscopy and confocal laser scanning microscopy. Key research organisms include Neurospora crassa, Allomyces macrogynus, and members of the Zygomycetes. Education: Ph.D., University of Georgia (1989); M.Sc., Stephen F. Austin State University. Research Interests: Fungal cell growth mechanisms, Spitzenkörper dynamics, microtubule and actin cytoskeleton organization, and the application of microscopy to study fungal ultrastructure. His work bridges molecular biology, cell biology, and evolutionary mycology to understand how cellular structures drive fungal morphogenesis. Grants and Collaborations: Principal investigator on NSF-funded projects including the ZyGoLife initiative and studies on cyanobacterial bioenergy. Collaborates with researchers in plant biology, microscopy, and synthetic biology. Teaching: Courses include BIO 495 Undergraduate Research , BIO 504 Bioimaging , and MCB 555 Advanced Molecular & Cellular Science . Service: Serves on editorial boards (e.g., Mycologia ), chairs microscopy-related committees, and advises on federal grant panels (NSF).

Hong-Li Chouمشاهده پروفایل

استاد پژوهش

• RNA Biology
• Plant Molecular Biology
• Post-Transcriptional Regulation
• +۳ مورد دیگر

Hong-Li Chou is an Assistant Research Professor in the Department of Biology at Pennsylvania State University, affiliated with the Assmann Lab. His research focuses on RNA biology, molecular mechanisms of mRNA localization, and plant developmental processes, particularly in rice endosperm and seed storage proteins. His work investigates RNA-binding proteins like OsTudor-SN and RBP-L that regulate mRNA transport and subcellular localization, impacting seed development and storage protein synthesis. Chou also explores liquid-liquid phase separation mediated by RNA multimerization and the structural-functional relationships of RNA molecules. Publications highlight advancements in understanding plant mRNA trafficking pathways, paramural body formation in rice mutants, and applications in biotechnology such as enhancing cellulase expression in transgenic rice. While no awards are explicitly mentioned, his contributions span plant molecular biology, cellular mechanisms, and environmental health studies. Chou collaborates within the Assmann Lab to advance knowledge of post-transcriptional regulation and its implications for plant growth and agricultural biotechnology.

• Cell Biology
• Neuroscience
• Kidney Disease
• +۳ مورد دیگر

Kasturi Roy, PhD, is an Associate Research Scientist in the Department of Internal Medicine Nephrology at Yale School of Medicine, affiliated with the Somlo Laboratory. She holds a PhD in Biotechnology from the University of Calcutta (2014). Her research focuses on cilia biology, neuronal cotransporters (NKCC1/KCC2), and the molecular mechanisms underlying kidney diseases like polycystic kidney disease (PKD) and neurodegenerative disorders such as Alzheimer’s. Her work integrates structural biology, proteomics, and cellular signaling to understand lipid modifications, palmitoylation, and protein interactions in disease contexts. Key research areas include the structural basis of ion transport inhibition by diuretics, cilia-dependent signaling pathways, and the role of Grb2 in cytoskeletal stability and autophagy. Dr. Roy collaborates with prominent researchers like Biff Forbush, Gary Rudnick, and Zhaoxia Sun, contributing to high-impact studies published in Cell , Nature Communications , and Journal of Biological Chemistry . Her publications highlight advancements in serotonin transporter inhibitors, NKCC1 inhibition mechanisms, and the structural dynamics of neuronal transporters. Ongoing projects explore ciliary protein stability, PKD pathogenesis, and the interplay between receptor tyrosine kinases in metabolic and neurological disorders. Dr. Roy’s work bridges basic science and translational medicine, with implications for developing targeted therapies for kidney diseases and neurodegenerative conditions. She is actively involved in the Somlo Laboratory, contributing to interdisciplinary teams studying cilia dysfunction and cystic disorders.

• Neurology
• Alzheimer’s Disease
• Neurodegenerative Disorders
• +۳ مورد دیگر

Yifei Cai is an Associate Research Scientist in the Department of Neurology at Yale School of Medicine, Yale University. Their research focuses on neurodegenerative diseases, particularly Alzheimer’s disease, leveraging proteomics, induced pluripotent stem cell (iPSC) modeling, and spatial imaging techniques to uncover disease mechanisms. Cai’s work addresses axonal pathology, myelin-axon interface vulnerabilities, and therapeutic targets. They have contributed to understanding schizophrenia-related phenotypes in genetic mouse models and the role of microRNAs in neurodegenerative disorders. Research interests include Alzheimer’s disease mechanisms, proteomics applications in neuroscience, iPSC-based disease modeling, and RNA regulation in neurodevelopmental and neurodegenerative processes. Their recent studies highlight advancements in reversing axonal pathologies and identifying molecular pathways critical to disease progression. Collaborations span interdisciplinary approaches, integrating computational methods with experimental biology. Publications since 2013 reflect a trajectory from bioinformatics applications in genetics to specialized neurodegenerative research. No awards or grants are explicitly listed, though their research aligns with major themes in neurology and translational medicine.

• Neurodegenerative Diseases
• Parkinson's Disease
• Neuronal Ceroid-Lipofuscinosis
• +۳ مورد دیگر

Sreeganga Chandra is an Associate Professor in the Departments of Neurology and Neuroscience at the Yale School of Medicine. Her research focuses on synaptic biology and neurodegeneration, particularly Parkinson’s disease (PD) and neuronal ceroid lipofuscinosis (NCL). She investigates how disruptions in synaptic proteostasis contribute to these disorders. Key areas include synapse maintenance mechanisms, presynaptic dysfunction, and the role of proteins like α-synuclein and CSPα. Chandra’s lab employs mouse models, human iPSC-derived neurons, and advanced techniques like proteomics and functional imaging. Notable findings include the identification of synaptic vesicle sorting defects in PD and the role of auxilin in disease progression. She has been recognized for contributions to understanding olfactory deficits in PD and the interplay between endolysosomal pathways and neurodegeneration. Chandra holds a PhD in Chemistry from Purdue University and completed postdoctoral training with Thomas C. Südhof.

• Molecular Biology
• Neurology
• Genetics
• +۴ مورد دیگر

Richard Young, MD is an Associate Clinical Professor in the Department of Pediatrics and Neurology at Yale School of Medicine. He received his MD from Yale University in 1973. His research focuses on molecular mechanisms underlying neurodegenerative diseases, RNA biology, and epigenetic regulation, with recent work exploring protein compartmentalization and microglia roles in Alzheimer’s and multiple sclerosis. Board certified in Pediatrics and Neurology with Special Qualification in Child Neurology, he maintains clinical expertise in pediatric neurology while advancing translational research. Education: MD, Yale University School of Medicine (1973) Research Interests: RNA-mediated regulatory mechanisms in disease Epigenomic modulation in neurodegenerative disorders Protein dynamics and cellular compartmentalization CRISPR-based screening of microglial functions Publications Trends: Recent work emphasizes interdisciplinary approaches combining genomics, epigenetics, and cell biology to address chronic disease mechanisms. Key contributions include defining proteolethargy as a novel disease pathway and characterizing MECP2’s role in neuronal transcription. Early-career studies established foundational knowledge of RNA polymerase II subunit functions in yeast. Awards/Grants: No specific awards/grants listed in available texts. Advising: No trainee names documented here. Labs/Teams: Affiliated with Yale School of Medicine’s research programs in neurodegenerative diseases and molecular medicine.

• Cardiovascular Diseases
• Cell Physiology
• Molecular Biology
• +۳ مورد دیگر

Dr. Jie Liu is a Lecturer at the University of Sydney's Sydney Medical School within the Faculty of Medicine and Health. He is affiliated with the Charles Perkins Centre, focusing on themes like Obesity, Diabetes, and Cardiovascular Disease. His research integrates molecular biology, nanotechnology, and biomedical imaging to explore cardiovascular pathophysiology and cellular mechanisms. Research interests include cardiac electrophysiology, fluorescent probe development, and nanomaterials for medical applications. Key projects involve sinoatrial node function, nucleolar RNA dynamics, and photodynamic therapy using advanced imaging techniques. Dr. Liu's work bridges basic science and translational medicine, addressing challenges in cardiology and cell biology. Recent publications highlight innovations in three-photon imaging, nucleophagy regulation, and biological pacemaker engineering. His studies often employ cutting-edge techniques like single-cell RNA sequencing and super-resolution microscopy. Collaborations span cardiology, materials science, and bioengineering, reflecting interdisciplinary research priorities. No explicit scientific awards are listed, though his prolific publication record indicates recognition in the field. His work contributes to understanding aging effects on cardiac rhythm, nanotechnology-driven diagnostics, and targeted therapy development.

Christine K. Payneمشاهده پروفایل

استاد

• Nanomaterials Science
• Cell Biology
• Biomedical Engineering
• +۳ مورد دیگر

Christine K. Payne is the Yoh Family Professor of Mechanical Engineering and Materials Science at Duke University's Pratt School of Engineering, with a secondary appointment in Chemistry at Trinity College of Arts & Sciences. She holds the Alstadt Chair and leads the Payne Lab, focusing on nanoparticle-cell interactions, protein corona dynamics, and their implications in health and disease. Her research integrates materials science, cell biology, and spectroscopy to study nanoparticle toxicity, autoimmune mechanisms, and allergic responses. Education: PhD in Chemistry from UC Berkeley (2003), BS from the University of Chicago (1998). Research Interests: Cellular uptake mechanisms of nanomaterials, protein corona formation, nanoparticle-induced oxidative stress, and translational applications in biomedicine and environmental health. Key projects include studying titanium dioxide nanoparticles in industrial settings and allergen-nanoparticle synergies. Publications: Recent work explores DNA coronas' resistance to nucleases (Biophysical Journal), TiO₂ nanoparticle toxicity (J. Phys. Chem. B), and allergen-nanotube interactions (ACS Nano). Her studies highlight interdisciplinary approaches to understand nanoparticle-biological interfaces. Awards: Named Bass Professor for Excellence in Teaching and Research (2020), and recipient of NSF grants for machine learning in protein corona prediction and interdisciplinary training programs. Grants: Current funding includes NSF's "Machine Learning for the Protein Corona" (2024-2027) and North Carolina State University's allergy modulation research (2021-2026). She also leads a Burroughs Wellcome Fund training initiative (2024-2025). Labs/Teams: The Payne Lab at Duke emphasizes interdisciplinary training, with projects spanning microscopy, nanotechnology, and cell biology. Collaborations include work with James C. Bonner on allergen corona effects and David S. Pisetsky on DNA-nanoparticle interactions.

• Biophysics
• Soft Matter Physics
• Biomolecular Condensates
• +۳ مورد دیگر

Sam Wilken is a Research Fellow in the Saleh Group at the Department of BioEngineering, University of California, Santa Barbara (UCSB). His work focuses on biomolecular condensates, phase-separated systems, and soft matter physics. He investigates the dynamics of DNA-based liquids, nucleation mechanisms in biomolecular systems, and the interplay between electrostatic interactions and base-pairing in phase separation processes. His research bridges biophysics, materials science, and statistical mechanics. Key areas of exploration include spatial organization of DNA condensates, hyperuniformity in phase-separated systems, and the engineering of DNA droplet properties through surface modifications. Wilken's studies often employ mesoscale self-organization principles and advanced characterization techniques to understand how biological and synthetic systems achieve functional spatial organization. His recent work reveals trends in studying both equilibrium (e.g., nucleation dynamics) and non-equilibrium (e.g., jamming transitions) phenomena in biomolecular and colloidal systems. While no awards are explicitly mentioned, his publications indicate sustained contributions to understanding phase behavior in complex fluids and biological systems. He collaborates within the Saleh Group to advance applications in reconfigurable materials and evolutionary computation-optimized systems.

David J. Waxmanمشاهده پروفایل

استاد

• Genomic and Epigenetic Mechanisms
• Molecular Endocrinology
• Cancer Therapy
• +۴ مورد دیگر

David J. Waxman is a Professor of Biology, Medicine, and Biomedical Engineering at Boston University. He holds a PhD from Harvard University and leads a research program focusing on genomic, epigenetic, and hormonal mechanisms regulating liver gene expression, environmental chemical toxicity, and cancer immunotherapy. His work combines advanced genomic technologies like scRNA-seq and ChIP-seq with mouse models to study sex-differential gene expression, environmental toxin impacts, and anti-tumor immune responses. Research Interests: Genomic/epigenetic control of liver gene expression Hormonal regulation via growth hormone (GH) and nuclear receptors Environmental chemicals and developmental toxicity Immunogenic chemotherapy strategies Non-coding RNA roles in liver physiology Recent Work Trends: Over 150 publications highlight his focus on sex-biased gene networks, metronomic chemotherapy’s immune activation, and environmental chemical-induced epigenetic reprogramming. Key techniques include CRISPR-based epigenetic editing and single-cell transcriptomics. Labs/Teams: Directs a multi-disciplinary lab integrating molecular biology, bioinformatics, and preclinical oncology studies. Collaborates with institutions like Harvard and MIT on translational projects.

Paul Hippenmeyerمشاهده پروفایل

استاد مدعو

• Biomedical Technologies
• Therapeutics Development
• Drug Discovery
• +۴ مورد دیگر

Paul Hippenmeyer is an Adjunct Professor in the Management Department at the University of Missouri’s Robert J. Trulaske Sr. College of Business. He holds a Ph.D. in Cellular and Molecular Biology (St. Louis University, 1984) and an MBA (University of Missouri-St. Louis, 2006). His career spans over 30 years in academia and industry, focusing on biomedical technologies, drug discovery, and technology commercialization. Before academia, Hippenmeyer served as Business Development Director at Washington University in St. Louis (until 2020) and Senior Licensing Associate at the University of Missouri (2009–2015), where he evaluated and licensed biomedical innovations. His industry experience includes roles at Monsanto, Searle, and Pharmacia, where he led oncology research and antiviral drug discovery programs. Notably, he held the Science Fellow title in oncology drug development and directed global collaborations in protease inhibitor research. His research interests emphasize translational medicine, with a focus on therapeutics, diagnostics, and biomarkers. He has authored 20+ peer-reviewed publications and patents, contributing to advancements in cytomegalovirus protease inhibition and recombinant protein production. His work bridges academia and industry, promoting technology transfer and startup mentorship. Hippenmeyer’s publications span viral pathogenesis, drug discovery, and biotechnology. Recent work explores liver disease therapies and cancer biomarkers. He remains active in teaching and advising startups, leveraging his expertise in business intelligence and technology management. Professional contributions include service as Assistant Vice President of the Association of University Technology Managers (AUTM), managing licensing surveys. His career reflects a commitment to advancing biomedical innovation through collaborative research and commercialization.

• Plant Biology
• Circadian Rhythms
• Genetics
• +۳ مورد دیگر

James Ronald is a Research Fellow at the University of York, specializing in plant biology and circadian rhythms. He holds PhDs in Biology and Chemistry and previously served as a Research Associate in Biology. His work focuses on understanding how circadian clocks integrate environmental signals like light and temperature to regulate plant physiology, development, and gene expression. Key areas include epistatic interactions in circadian components (e.g., ELF3, PRR9), phototropism mechanisms, and the molecular basis of plant developmental transitions. Recent research highlights include studies on diurnal gene expression dynamics in Arabidopsis thaliana , the role of ELF4 in temperature signaling between plant organs, and the genetic basis of circadian rhythm entrainment. His publications span topics ranging from light-dependent clock regulation to sucrose metabolism interactions with the circadian system. Dr. Ronald’s work emphasizes systems-level approaches, combining genomic analysis, protein localization studies, and environmental stress experiments. Despite his prolific output, no scientific awards or grants are explicitly listed in the provided texts. His research continues to bridge molecular mechanisms with ecological relevance in plant timing systems.

Jing Liمشاهده پروفایل

استاد

• Computational Biology
• Bioinformatics
• Statistical Genomics
• +۳ مورد دیگر

Jing Li is an Arthur L. Parker Professor in the Department of Computer and Data Sciences at Case School of Engineering and holds a dual appointment as Professor in the Department of Population and Quantitative Health Sciences at the School of Medicine, Case Western Reserve University. She is also affiliated with the Cleveland Institute for Computational Biology. Her research focuses on computational approaches for genomics, bioinformatics, and systems biology, with a strong emphasis on big data analytics. Key interests include computational biology, statistical genomics, machine learning applications in healthcare, and drug repositioning strategies. Her work spans interdisciplinary collaborations, integrating machine learning techniques with biomedical data to address challenges in precision medicine, disease modeling, and drug discovery. Notable projects include developing algorithms for haplotype inference, drug-target interaction prediction, and analysis of genomic variations in health and disease. Publications span topics like SARS-CoV-2 mutation dynamics, wearable technology for postoperative monitoring, and deep learning for medical imaging. Her methodologies often combine computational modeling with high-throughput genomic data to uncover biological mechanisms and clinical insights.

Elizabeth Vierlingمشاهده پروفایل

استاد

• Plant Molecular Biology
• Molecular Chaperones
• Protein Folding
• +۳ مورد دیگر

Elizabeth Vierling is a Distinguished Professor in the Department of Biochemistry and Molecular Biology at the University of Massachusetts Amherst. Her research focuses on molecular chaperones, stress responses, and nitric oxide metabolism in plants. She holds a PhD from the University of Chicago and has conducted postdoctoral research at the University of Georgia. Her lab investigates protein folding mechanisms, small heat shock proteins (sHSPs), and the HSP100 chaperone system. Recent work includes studies on mitochondrial function, nitric oxide regulation, and stress tolerance in plants like Arabidopsis and Synechocystis. Vierling leads an NSF-funded project exploring mitochondrial roles in plant productivity under climate change. Key research themes include protein aggregation/dissagregation, translational regulation during stress, and enzymatic regulation of nitric oxide homeostasis. Her lab employs biochemical, genetic, and structural approaches, with notable contributions to understanding sHSP oligomer dynamics and stress-induced protein interactions. Recent publications highlight mitochondrial-nucleoid interactions, NO signaling in reproduction, and heat tolerance mechanisms. The lab maintains active collaborations and has secured significant funding for interdisciplinary projects linking basic biology to agricultural resilience.

• Urologic Oncology
• Biomarker Development
• Clinical Trial Design
• +۳ مورد دیگر

Fed Ghali, MD, is an Assistant Professor of Urology at the Yale School of Medicine, specializing in urologic oncology with expertise in bladder, ureter, kidney, and testicular cancers. He holds affiliations with Yale Cancer Center, Prostate & Urologic Cancers Program, and Urologic Oncology at Yale School of Medicine. Ghali completed his medical degree at Geisel School of Medicine, residency in Urology at UC San Diego, and a Society of Urologic Oncology fellowship at the University of Washington. His research focuses on clinical trial design, biomarker development for bladder cancer, and improving patient outcomes through personalized therapy. Notable interests include non-muscle invasive bladder cancer recurrence detection via urinary DNA analysis and optimizing treatment protocols for variant histology cancers. He collaborates with institutions nationally to advance therapeutic strategies and biomarker discovery. Ghali emphasizes patient-centered care, balancing high-volume clinical practice with compassionate individualized treatment. He actively participates in Yale's translational research initiatives and clinical trials to bring cutting-edge therapies to patients. His work highlights the integration of surgical innovation, molecular diagnostics, and clinical research in oncology.