معرفی
Christine K. Payne is the Yoh Family Professor of Mechanical Engineering and Materials Science at Duke University's Pratt School of Engineering, with a secondary appointment in Chemistry at Trinity College of Arts & Sciences. She holds the Alstadt Chair and leads the Payne Lab, focusing on nanoparticle-cell interactions, protein corona dynamics, and their implications in health and disease. Her research integrates materials science, cell biology, and spectroscopy to study nanoparticle toxicity, autoimmune mechanisms, and allergic responses.
Education: PhD in Chemistry from UC Berkeley (2003), BS from the University of Chicago (1998).
Research Interests: Cellular uptake mechanisms of nanomaterials, protein corona formation, nanoparticle-induced oxidative stress, and translational applications in biomedicine and environmental health. Key projects include studying titanium dioxide nanoparticles in industrial settings and allergen-nanoparticle synergies.
Publications: Recent work explores DNA coronas' resistance to nucleases (Biophysical Journal), TiO₂ nanoparticle toxicity (J. Phys. Chem. B), and allergen-nanotube interactions (ACS Nano). Her studies highlight interdisciplinary approaches to understand nanoparticle-biological interfaces.
Awards: Named Bass Professor for Excellence in Teaching and Research (2020), and recipient of NSF grants for machine learning in protein corona prediction and interdisciplinary training programs.
Grants: Current funding includes NSF's "Machine Learning for the Protein Corona" (2024-2027) and North Carolina State University's allergy modulation research (2021-2026). She also leads a Burroughs Wellcome Fund training initiative (2024-2025).
Labs/Teams: The Payne Lab at Duke emphasizes interdisciplinary training, with projects spanning microscopy, nanotechnology, and cell biology. Collaborations include work with James C. Bonner on allergen corona effects and David S. Pisetsky on DNA-nanoparticle interactions.
