جست‌وجوی استاد و پژوهشگر

Anne Simonمشاهده پروفایل

استاد

• Zoopoetics
• Ecopoetics
• Environmental Humanities
• +۳ مورد دیگر

Anne Simon is a Research Director at CNRS and Professor at École normale supérieure (ENS-PSL), where she leads the Department of Literatures and Language. She founded and directs the international PhilOfr team (Centre international d’étude de la philosophie française contemporaine) and contributes to research blogs Animots, Pôle Proust, and Prix Recherche au Présent. Ph.D. in Literature (Paris-Sorbonne, 1999) Habilitation à diriger des recherches (Paris-Sorbonne, 2014) Formerly affiliated with THALIM (2001-2010) and CRAL (2010-2021) Her research intersects literature and philosophy through zoopoetics , exploring how animal studies, environmental humanities, and ethics shape literary creation. She examines bodily mutations, gender representations, and the disruptive influence of Proust on 20th-century thinkers like Merleau-Ponty and Deleuze. Her work also bridges ecopoetics and literature-ethology interactions. Recent articles and edited collections (2017-2025) focus on satirical zoomorphism, cross-disciplinary zoopoetics, and ethical dimensions of human-animal relations in Francophone contexts. She has co-organized international colloquiums and contributed to journals like Revue des Sciences Humaines and Contemporary French and Francophone Studies . Professor Simon has taught in EHESS/ENS Masters programs, directed ANR-funded projects (2010-2014), and serves on editorial boards including Romanic Review and Billebaude . She co-founded the Prix Recherche au Présent for doctoral candidates and evaluates for the Prix Jacques Lacarrière .

• Cytokine receptor signaling
• JAK-STAT pathway
• Epigenetic regulation
• +۵ مورد دیگر

Stefan N. Constantinescu is Professor of Cancer Signalling at the University of Oxford's Ludwig Institute for Cancer Research, Head of the Cell Signalling Pole at Université catholique de Louvain’s de Duve Institute, and Director of Research (Honorary) at FRS-FNRS Belgium. He serves on the European Research Council’s advanced grants panels and leads the Constantinescu research group focused on blood cancer mechanisms. His research investigates signaling pathways in myeloid malignancies, particularly how cytokine receptor mutations (JAK-STAT), epigenetic regulators, and chromatin dynamics drive chronic myeloproliferative neoplasms (MPNs) and their progression to acute leukaemia. Key objectives include elucidating mutant calreticulin mechanisms, thrombopoietin receptor dysregulation, and chromosome 21 amplification in blast-phase transformation. His group's publication trends reveal intense focus on MPN pathogenesis through structural biology approaches, with recent work establishing secreted mutant calreticulins as rogue cytokines and identifying DYRK1A as a therapeutic target in blast-phase transformation. The research consistently bridges basic molecular mechanisms with clinical translation in haematological malignancies. Awards and honors include: Full Member of the Royal Academy of Medicine of Belgium President of the Federation of European Academies of Medicine (2021-2024) Professor Constantinescu advises DPhil students including Sara Abdel Malak and Nandini Mozumdar while leading collaborative research across Oxford and Louvain. His group maintains active grants exploring signaling-epigenetic crosstalk in blood cancers, with recent funding supporting chromothripsis and DYRK1A overexpression studies. The team includes postdoctoral fellow Akbar Shahid and utilizes advanced genomic and structural methodologies. The Constantinescu lab operates within Oxford's Ludwig Cancer Research branch, leveraging the Medical Sciences Division's infrastructure for translational cancer research. Current work focuses on targeting epigenetic dysregulation during MPN progression to secondary acute myeloid leukaemia.

• Developmental Biology
• Regenerative Medicine
• Cardiovascular Development
• +۳ مورد دیگر

Mathilda Mommersteeg is an Associate Professor of Developmental and Regenerative Medicine at the University of Oxford's Department of Physiology, Anatomy & Genetics (DPAG), and Deputy Director of Graduate Studies at St Cross College. She holds a PhD from the University of Amsterdam (2009) and conducted postdoctoral research at University College London (UCL), supported by an EMBO fellowship. Her work focuses on understanding molecular mechanisms underlying heart regeneration and development, particularly using zebrafish and Mexican cavefish models. Key research areas include Slit-Robo signaling pathways, cardiac innervation, and the genetic basis of regenerative success. Her research has identified critical roles for genes like Lrrc10 and Runx1 in heart regeneration, and she has pioneered studies on population-specific differences in regenerative capacity between surface and cave-dwelling Mexican cavefish. Mommersteeg's contributions span developmental cardiology, regenerative biology, and comparative genomics, with a focus on translating findings to improve human cardiac repair strategies. Education: PhD in Developmental Biology, University of Amsterdam (2009) Labs/Groups: Mommersteeg Group (Oxford) Grants/Funding: Supported by the British Heart Foundation (BHF) and other initiatives Her recent work emphasizes the interplay between cardiomyocyte proliferation and fibrotic responses in regeneration failure, with studies revealing how genetic and environmental factors influence repair outcomes.

• Cancer Research
• Bioinformatics
• Proteomics
• +۳ مورد دیگر

Dr. Rebecca Poulos is an NHMRC Early Career Fellow and Conjoint Lecturer at the Children’s Medical Research Institute, University of Sydney. Her research focuses on cancer genomics, proteomics, and data science, particularly integrating multiomic data to uncover cancer biomarkers and drug response mechanisms. She holds a BBus, BSc (Hons) with a University Medal, and a PhD from UNSW Sydney. Key research interests include cancer driver mutations, proteogenomics, and machine learning for multi-omics integration. Notable achievements include an NHMRC Early Career Fellowship and the Cancer Institute NSW Rising Star PhD Student Award. Her work spans pediatric cancer proteomics, drug response prediction, and reproducible large-scale proteomics. Recent studies highlight her contributions to cancer pathway modeling (DeePathNet), pediatric cancer molecular signatures, and proteomic stratification of prostate cancer. She leads projects funded by NHMRC and Sydney Cancer Partners, advancing precision medicine through proteomics. Her lab is embedded in the Cancer Data Science Group (ProCan), collaborating on pan-cancer proteomic maps and clinical applications.

Jorge Z. Torresمشاهده پروفایل

استاد

• Biochemistry
• Systems Biology
• Cell Division
• +۵ مورد دیگر

Jorge Z. Torres is a Professor at the University of California, Los Angeles (UCLA) in the Department of Chemistry & Biochemistry. His research focuses on mitotic spindle formation, ubiquitin ligases, and small molecule targeting for cancer therapy. Academic affiliation: UCLA Department of Chemistry & Biochemistry Research areas: Cell division, Systems biology, Chemical biology Research Interests: The Torres lab investigates mitotic spindle assembly mechanisms, disease-linked ubiquitin ligases, and chemical screens for cell division inhibitors. Key work includes proteomic analyses of spindle proteins, characterization of microtubule-associated enzymes, and development of software tools like CANVS for interaction data visualization. Publication Trends: Recent articles emphasize spindle assembly regulation (2025), cilia length modulation (2024), and biochemical mechanisms of ubiquitination (2023). Earlier work covers phospho-regulation (2020), phase separation (2020), and comprehensive reviews on katanin family proteins (2021) and Plk1 inhibition strategies. Lab Activities: The lab develops chemical inhibitors (e.g., MI-181, Leusin-1) using virtual screening and pharmacophore modeling. Techniques include human cell lines, in vitro systems, and multi-omics approaches to map protein interactions and drug effects.

Karen Schindlerمشاهده پروفایل

استاد

• Reproductive Genetics
• Meiosis
• Aneuploidy
• +۱۲ مورد دیگر

Karen Schindler is a Professor in the Department of Genetics at Rutgers University–New Brunswick, within the School of Arts and Sciences. She leads an active research laboratory focused on understanding the molecular regulation of female meiosis, particularly in mouse oocytes, to uncover the causes of aneuploidy, which underlies infertility, miscarriage, and developmental disorders such as Down Syndrome. Her research centers on signal transduction networks in oocyte maturation, with a strong emphasis on protein kinases (especially Aurora kinases A, B, and C) and protein phosphatases, including Haspin and CDC14B. She investigates how these enzymes regulate chromosome segregation, spindle assembly, and cell cycle progression during meiosis. Her lab uses advanced genetic, biochemical, and imaging techniques in mouse models to dissect conserved mechanisms relevant to human reproductive health. The recent publications (2014–2024) show a consistent focus on Aurora kinases, histone modifications, and maternal effect genes. Trends include the functional divergence of Aurora B and C, the role of kinase networks in acentrosomal spindle formation, and the translational implications of mutations linked to aneuploidy. Her work bridges basic cell biology and clinical reproductive medicine. Board of Trustees Award for Excellence in Research (2024–2025) Karen Schindler mentors graduate students in the Molecular Biosciences program at Rutgers. Her lab has been supported by competitive funding, as evidenced by her extensive publication record in top-tier journals. She has developed methods for gene function analysis in meiosis and contributes to both research and education through publications in journals like Journal of Visualized Experiments and The Scientist . She leads the Schindler Lab, which is dedicated to uncovering the mechanisms that make female meiosis error-prone. The lab combines molecular genetics, cell biology, and model organism approaches to explore fundamental questions in gametogenesis and chromosomal stability.

• Cancer Genomics
• Tumor Immunology
• Colorectal Cancer
• +۵ مورد دیگر

Dr. David Church is a researcher at the Centre for Human Genetics, University of Oxford, based at the Henry Wellcome Building of Genomic Medicine. He is affiliated with Brasenose College and collaborates with prominent researchers including Ian Tomlinson and Dr. Claire Palles at Oxford, as well as international collaborators at Leiden University Medical Centre and University of Zurich. Dr. Church's research focuses on tumor-immune system interactions, particularly in cancers with high mutational loads from polymerase proofreading domain mutations. His work demonstrates that ultramutated POLE-mutant colorectal and endometrial cancers have excellent prognoses due to strong anti-tumor T cell responses against numerous neoantigens. His research spans cancer genomics, immunotherapy mechanisms, and molecular classification of gastrointestinal and gynecological cancers. Analysis of Dr. Church's publications reveals consistent focus on mismatch repair-deficient and POLE-mutant cancers across multiple tumor types. His work integrates genomic analysis with immune profiling to understand tumor evolution, immune evasion mechanisms, and biomarker development for immunotherapy response. Key themes include molecular classification systems, tumor microenvironment characterization, and the development of precision medicine approaches for cancer treatment. Dr. Church leads significant collaborative efforts including the RAINBO clinical trial program, which investigates molecular class-directed adjuvant treatment strategies for endometrial cancer through four international clinical trials. His research has direct implications for treatment de-escalation in favorable prognosis subtypes and novel therapeutic approaches for immunotherapy-resistant cancers.

• Cystic Fibrosis
• Lung Cancer
• Cancer Therapeutics
• +۷ مورد دیگر

Judith Coppinger is a Senior Lecturer at RCSI's School of Pharmacy and Biomolecular Sciences, with dual affiliation as Principal Investigator at the National Children’s Research Centre since 2017. Her academic journey includes a PhD in Pharmacology from RCSI (2004), postdoctoral training at the Scripps Research Institute (2005-2011), and faculty roles at UC San Diego (2011-2013) and University College Dublin (2013-2017). Her research focuses on omics-based approaches to uncover dysregulated protein interactions in diseases like cystic fibrosis and cancer, with a particular emphasis on exosome-mediated signaling, kinase inhibitors for CFTR restoration, and BAG3 as a cancer therapeutic target. Key research areas include cystic fibrosis pathophysiology, lung cancer signaling pathways, and translational therapeutics. Her work spans basic science to clinical translation, such as investigating exosomes as biomarkers for disease progression and targeting the PI3K/Akt/mTOR pathway in cystic fibrosis. She has secured major grants including Science Foundation Ireland funding for exosome-based therapies and the Cystic Fibrosis Foundation for EV biomarker studies in CF. Judith has received awards including the Career Development Award (2014), Isenberg Fellowship (2011), and New Investigators Travel Award (2010). Her lab at RCSI collaborates with Trinity College Dublin and the National Children’s Research Centre to advance research in respiratory medicine and cancer biology. Teaching and supervision activities are integral to her role, contributing to training future biomedical researchers.

David Hsiehمشاهده پروفایل

استادیار

• Liver Cancer Research
• Cancer Therapeutics
• Translational Medicine
• +۳ مورد دیگر

David Hsieh, M.D., is an Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center, specializing in Hematology and Oncology. He leads clinical trials for liver cancers, including hepatocellular carcinoma and cholangiocarcinoma, and investigates mechanisms of cancer therapy resistance and treatment biomarkers. His work also addresses biases and processes in scientific research and healthcare policy. Education: Medical Degree: University of Arizona College of Medicine Residency: Internal Medicine at Mount Auburn Hospital Fellowship: Hematology and Oncology at UT Southwestern Medical Center Research Interests: Focuses on translational research in liver cancers, including drug efficacy mechanisms, biomarker development, and clinical trial innovations. Explores systemic biases in oncology trials and healthcare policies affecting drug coverage and accessibility. Engages in investigating racial disparities in cancer outcomes and mutation patterns. Scientific Awards: Early Career Investigator Award, Cancer Prevention and Research Institute of Texas Advising & Grants: Active in clinical trial design and leadership, though specific advising or grant details are not explicitly listed. Collaborates on high-impact trials like IMbrave150 and IMbrave050. Lab/Teams: Member of the Division of Hematology and Oncology at UT Southwestern, contributing to both clinical care and translational research initiatives.

• Hematology
• Oncology
• Immunotherapy
• +۶ مورد دیگر

Emil Lou, MD, PhD, FACP is a Professor of Medicine in the Division of Hematology, Oncology, and Transplantation at the University of Minnesota Medical School. His research focuses on advancing CRISPR-engineered immunotherapies, understanding tumor microenvironment dynamics, and developing AI-driven liquid biopsy platforms for precision oncology. He actively investigates therapeutic resistance mechanisms in gastrointestinal cancers and neuroendocrine neoplasms through molecular and immunological characterization. Broad research areas: Hematology, Oncology, Immunotherapy, CRISPR-Cas9, Liquid Biopsy Clinical focus: Gastrointestinal cancers, neuroendocrine tumors, glioblastoma, and ovarian cancer Key technologies: Multi-omic analysis, AI-based diagnostics, Tumor-Infiltrating Lymphocyte engineering His recent work includes first-in-human trials for CRISPR-edited T-cell therapies and biomarker discovery for immune checkpoint inhibitors. Awards include recognition as a Fellow of the American College of Physicians (FACP).

Lauren Aoudeمشاهده پروفایل

پژوهشگر ارشد

• Precision Oncology
• Cancer Genomics
• Melanoma Research
• +۳ مورد دیگر

Dr. Lauren Aoude is a Senior Research Fellow at the Frazer Institute, University of Queensland, specializing in precision oncology and genomic medicine. Her research integrates genomic sequencing with clinical data to develop prognostic tools and therapeutic strategies for oesophageal adenocarcinoma and melanoma. She holds prestigious fellowships including the NHMRC Emerging Leader Fellowship and leads innovative projects on patient-derived organoid models for personalized cancer treatment. Her research focuses on genomic biomarkers, liquid biopsy applications, and tumor microenvironment characterization, with strong emphasis on translating findings into clinical practice. She coordinates the Master of Medicine Skin Cancer program, mentoring future medical professionals in evidence-based oncology practice. Significant awards include: NHMRC Early Career Fellowship (2016-2021) UQ Amplify Fellowship (2021) NHMRC Emerging Leader Fellowship (2025) Dr. Aoude leads translational research teams exploring ctDNA applications and organoid-based therapy screening, with collaborations extending across international cancer consortia focused on genomic oncology.

Chris Ka-Pun MOKمشاهده پروفایل

استادیار

• Virology
• Immunology
• Respiratory Diseases
• +۳ مورد دیگر

Prof. Chris Ka-Pun MOK is an Assistant Professor at the JC School of Public Health and Primary Care, Chinese University of Hong Kong (CUHK). He holds an honorary position as Assistant Professor at the HKU-Pasteur Research Pole. His research focuses on understanding the interplay between host adaptive immunity and viral determinants of respiratory viruses like influenza and coronaviruses through clinical, virological, and structural approaches. Education: BSc (Chemistry) from Hong Kong University of Science and Technology (HKUST), MPhil and PhD from The University of Hong Kong (HKU). Research interests include pathogenicity of zoonotic viruses, viral immunology in respiratory diseases, and developing prophylactic/treatment options for respiratory infections. He has contributed to high-impact studies on SARS-CoV-2 variants, vaccine efficacy, and cross-reactive antibody responses. Notable awards include recognition as one of the Best papers in Cell Reports (2020) and selection by C&EN’s Year in Chemistry 2020 for groundbreaking work on SARS-CoV-2 epitopes. Prof. MOK is actively involved in outbreak investigations through the Institute Pasteur International Network and serves as an Associate Editor for Frontiers in Immunology and Virology Journal .

• Gastrointestinal Oncology
• Colorectal Cancer
• Pancreatic Cancer
• +۴ مورد دیگر

Michael Cecchini, MD, is an Associate Professor of Medicine (Medical Oncology) at Yale School of Medicine, specializing in gastrointestinal cancers, including colorectal, pancreatic, and bile duct cancers. He is Co-Director of the Colorectal Program in the Center for Gastrointestinal Cancers and Medical Oncology Section Lead for the National Accreditation Program for Rectal Cancer. His clinical focus involves advanced gastrointestinal malignancies, and he leads multiple research trials exploring novel therapies and biomarkers. Dr. Cecchini received his MD from Albert Einstein College of Medicine (2012) and completed residency at Yale New Haven Hospital (2015), followed by a hematology/oncology fellowship (2018). Research interests include DNA repair mechanisms, immunotherapy, and translational oncology. He has received awards such as the Yale Cancer Center Clinical Research Award (2025) and the Young Investigator Award from the Conquer Cancer Foundation. His work spans clinical trials (e.g., perioperative FOLFIRINOX for pancreatic cancer) and genomic analyses (e.g., POLE/POLD1-altered colorectal cancers). Collaborations include studies on ctDNA, AI-driven imaging analysis, and targeted therapies for cholangiocarcinoma. Dr. Cecchini is actively involved in multidisciplinary care, leading teams in hyperthermic intraperitoneal chemotherapy (HIPEC) and the Oligometastatic Cancer Program. He contributes to educational initiatives, including mentoring fellows and teaching medical students. His clinical trials portfolio includes Phase I/II studies evaluating novel agents like ASP3082 and PC14586 for solid tumors.

Yajue Huangمشاهده پروفایل

دانشیار

• Diagnostic Cancer Pathology
• Gynecologic Cancers
• Ovarian Cancer
• +۳ مورد دیگر

Yajue Huang, M.D., Ph.D., serves as Associate Professor of Laboratory Medicine and Pathology and Consultant in the Division of Anatomic Pathology at Mayo Clinic in Rochester, Minnesota. She holds dual leadership roles as Director of the Cytopathology Laboratory and Section Head of Cytopathology since 2018, with primary responsibilities spanning diagnostic cancer pathology and gynecologic oncology research. Her academic foundation includes a Ph.D. in Pharmacology & Toxicology from Philadelphia College of Pharmacy & Science and a Bachelor of Medicine equivalent from Shanghai Jiao Tong University School of Medicine. Clinical training encompassed Pathology Residency/Chief Residency at Temple University Hospital, Surgical Pathology Fellowship at the University of Pennsylvania, Cytopathology Fellowship at Thomas Jefferson University Hospital, and Postdoctoral Research at Fox Chase Cancer Center. Dr. Huang's research centers on gynecologic malignancies with emphasis on ovarian high-grade serous carcinoma, ovarian clear-cell carcinoma, and endometrial cancer. She pioneers diagnostic cytopathology innovations and integrates artificial intelligence to enhance cancer diagnosis accuracy. Her work elucidates mechanisms of cancer development and progression, directly improving clinical management strategies for ovarian cancers through precise diagnostic frameworks. Analysis of her 15 most recent publications reveals dominant themes in gynecologic oncology, particularly molecular characterization of ovarian and endometrial cancers. Key methodological approaches include proteogenomics, computational pathology, and mutational signature analysis, with strong translational focus on biomarker discovery, therapeutic resistance mechanisms, and digital pathology applications for improved diagnostic precision. Her distinguished honors include: Anatomic Pathology Teaching Award (Temple University Hospital, 2011) Golden Apple Award (Temple University Medical School, 2011) Student Travel Award (FASEB Meeting, 1995) Multiple academic excellence awards from Shanghai Jiao Tong University (1986-1992) Dr. Huang actively contributes to professional advancement through executive roles in the Pennsylvania Association of Pathologists and Pathology Society of Philadelphia, while maintaining continuous membership in the American Society of Clinical Pathologists, College of American Pathologists, American Society of Cytopathology, and United States-Canadian Academy of Pathology. She directs Mayo Clinic's Cytopathology Laboratory where her team develops AI-enhanced diagnostic protocols and investigates tumor-stroma interactions in gynecologic cancers, maintaining strong collaborations with gynecologic oncology and molecular diagnostics research groups.

Gilbert Chuمشاهده پروفایل

استاد

• DNA Repair
• Oncology
• Biochemistry
• +۴ مورد دیگر

Gilbert Chu is a Professor of Medicine (Oncology) and Biochemistry at Stanford University , with affiliations to Bio-X , Maternal & Child Health Research Institute , and Stanford Cancer Institute . His career spans molecular biology, oncology, and medical device innovation. Education: A.B. in Physics, Princeton University (1967) Ph.D. in Physics, MIT (1973) M.D., Harvard Medical School (1980) Research Focus: DNA repair mechanisms, hyperammonemia diagnostics, and educational reform. Key contributions include nonhomologous end joining protein complexes , SAM/PAM microarray algorithms , and portable ammonia sensors . Award Highlights: 2024 Oscar Salvatierra Award for Medical Student Service Multiple Kaiser Teaching Awards (2020, 2015, 2014, 2007, 2003) 2018 American Physical Society Fellowship 1973 Giulio Racah Prize Patents: 5 U.S. patents in DNA repair and point-of-care diagnostics (1992-2014). Academic Leadership: Primary mentor in Biochemistry , Biophysics , and Cancer Biology Ph.D. programs; teaches courses like Perspectives on Cancer Care and The Teaching of Biochemistry .