معرفی
Mathilda Mommersteeg is an Associate Professor of Developmental and Regenerative Medicine at the University of Oxford's Department of Physiology, Anatomy & Genetics (DPAG), and Deputy Director of Graduate Studies at St Cross College. She holds a PhD from the University of Amsterdam (2009) and conducted postdoctoral research at University College London (UCL), supported by an EMBO fellowship. Her work focuses on understanding molecular mechanisms underlying heart regeneration and development, particularly using zebrafish and Mexican cavefish models. Key research areas include Slit-Robo signaling pathways, cardiac innervation, and the genetic basis of regenerative success.
Her research has identified critical roles for genes like Lrrc10 and Runx1 in heart regeneration, and she has pioneered studies on population-specific differences in regenerative capacity between surface and cave-dwelling Mexican cavefish. Mommersteeg's contributions span developmental cardiology, regenerative biology, and comparative genomics, with a focus on translating findings to improve human cardiac repair strategies.
- Education: PhD in Developmental Biology, University of Amsterdam (2009)
- Labs/Groups: Mommersteeg Group (Oxford)
- Grants/Funding: Supported by the British Heart Foundation (BHF) and other initiatives
Her recent work emphasizes the interplay between cardiomyocyte proliferation and fibrotic responses in regeneration failure, with studies revealing how genetic and environmental factors influence repair outcomes.
