جستجوی استاد راهنمای دانشگاهی

Dr. Gregor Schuhknecht is a Researcher and incoming Max-Planck Research Group Leader at the Max Planck Institute for Brain Research in Frankfurt, Germany. Starting December 2025, he will lead the Brain Algorithms and Circuits Group, focusing on computational neuroscience and neuronal circuitry in larval zebrafish. His work bridges experimental and computational approaches to understand brain algorithms enabling flexible behaviors. Education PhD in Neuroscience (2014–2019), Institute for Neuroinformatics, University of Zurich and ETH Zurich MSc in Biology (Neuroscience) (2012–2019), ETH Zurich BSc in Biosciences (2009–2012), Heidelberg University His research investigates how synaptic circuitry implements computational algorithms for sensorimotor processing, evidence accumulation, and behavior. Experimental approaches include functional imaging, optogenetics, connectomics, and computational modeling. The group will explore neuronal circuits across scales, from synapse to behavior, with a focus on biophysical properties and dynamic environmental adaptation. Recent publications highlight correlative light/electron microscopy, developmental activity-free circuit formation, and neocortical synapse analysis. Scientific Awards Meselson Prize (2024) Aspirational Neuroscience Award (2023) Best Publication Award (2021) Swiss National Science Foundation Fellowships (2021, 2019, 2018) Gregor Schuhknecht's lab will welcome graduate and postdoctoral researchers starting December 2025, focusing on experimental and computational systems neuroscience. He previously collaborated with Harvard University's Department of Molecular and Cellular Biology and the Department of Moritz Helmstaedter for connectomic analyses.

• Computational Neuroscience
• Systems Neuroscience
• Neuronal Circuitry
• +۴ مورد دیگر

James Briscoe is a Senior Group Leader at The Francis Crick Institute in London, where he leads a research group focused on developmental biology and morphogen signaling. He previously held positions at the Medical Research Council's National Institute for Medical Research, which later became part of the Francis Crick Institute. Education: BSc in Microbiology and Virology from the University of Warwick, UK PhD from Imperial Cancer Research Fund/King's College London Postdoctoral training at Columbia University with Thomas Jessell Dr. Briscoe's research focuses on the molecular and cellular mechanisms of graded signaling by morphogens and the role of transcriptional networks in cell fate specification. His laboratory employs a range of experimental and computational techniques using model systems including mouse and chick embryos and embryonic stem cells. His work has significant implications for understanding developmental processes and their relationship to disease. His recent publications demonstrate a continued focus on morphogen gradients, neural tube development, and computational approaches to understanding cell fate decisions. His research increasingly integrates single-cell technologies and computational modeling to unravel the complexities of developmental patterning. Scientific Awards and Honors: EMBO Young Investigator (2001) EMBO Gold Medal (2008) Elected to EMBO (2009) Fellow of the Academy of Medical Sciences (2019) Fellow of the Royal Society (2019) As Editor-in-Chief of the journal Development since 2018, Dr. Briscoe plays a significant role in shaping the field of developmental biology. His leadership extends to mentoring researchers and contributing to scientific policy discussions, as evidenced by his recent publication 'Science under siege: protecting scientific progress in turbulent times.' Dr. Briscoe's laboratory at the Crick Institute is well-equipped with access to advanced facilities including light microscopy, flow cytometry, genomics, and computational resources, enabling a multidisciplinary approach to developmental biology questions.

• Developmental Biology
• Molecular Signaling
• Transcriptional Networks
• +۴ مورد دیگر

Cristian Gómez Canela is a Full Professor in the Department of Analytical and Applied Chemistry at the School of Engineering, Ramon Llull University (IQS). He serves as Coordinator of the Master's Degree in Analytical Chemistry and is an active member of the Catalan Chemical Society (SCQ), representing SCQ in EuChems-EYCN. His academic journey includes a PhD in Chemistry from the University of Barcelona (2014), followed by postdoctoral research at IDAEA-CSIC and King's College University. Dr. Gómez Canela's research focuses on environmental analytical chemistry, particularly the optimization and validation of analytical methods based on liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and high-resolution mass spectrometry (HRMS) for determining organic pollutants in environmental samples. His work extends to metabolomics applied to aquatic organisms and the analysis of neurotoxic compounds in water systems. His research fingerprint reveals strong expertise in zebrafish models (100%), neurotransmitter analysis (66%), Daphnia magna studies (64%), and neurotoxicity assessment (21%). His recent publications (2024-2025) demonstrate a clear trend toward environmental neurotoxicology, with emphasis on the effects of pharmaceuticals and industrial pollutants on aquatic organisms. His work integrates advanced analytical techniques with biological endpoints to assess environmental risks, particularly focusing on neurological and cardiovascular impacts. The research spans method development for pollutant detection, environmental monitoring, and mechanistic studies of neurotoxic effects. Dr. Gómez Canela leads multiple significant research projects including CHEMIPARK (2024-2027) on passive sampling methodologies for environmental pollutants, GESPA (2022-2025) as part of the Environmental Process Engineering and Simulation Group, and several projects on neuroactive compounds in water systems. He has an impressive research output with 91 scientific publications from 2011-2025 and an h-index of 27 with over 2,000 citations. As a dedicated educator, he contributes to multiple academic programs including the Master in Analytical Chemistry, Master in Pharmaceutical Chemistry, and undergraduate degrees in Chemistry and Chemical Engineering. His research group GESPA represents a multidisciplinary team combining chemical engineering, biotechnology, and chemical analysis to advance environmental sustainability through theoretical and experimental approaches.

• Environmental Chemistry
• Analytical Chemistry
• Mass Spectrometry
• +۵ مورد دیگر

Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.

• Biochemistry
• Systems Biology
• Biological Regulation
• +۸ مورد دیگر

Johannes Larsch is a tenure-track Assistant Professor at the Center for Integrative Genomics within the Faculty of Biology and Medicine at Université de Lausanne (UNIL). His research focuses on understanding the neuronal mechanisms underlying social interactions, using larval zebrafish as a model organism. He employs advanced techniques like virtual reality and optical imaging to study how social signals are processed in the brain. Education: Bachelor of Biology, University of Konstanz, Germany PhD in Neurobiology, Rockefeller University, USA (lab of Cori Bargmann) Postdoc at Max Planck Institute of Neurobiology, Germany (with Herwig Baier) Research interests center on neuronal circuits driving group behavior, social recognition, and the interplay between genetics and environment in shaping behavior. His lab investigates how individual brains coordinate collective social behaviors through studies of neuronal activity and circuit dynamics. Current lab openings include fully funded PhD and PostDoc positions focused on social neuroscience and neurogenomics. Contact: johannes.larsch@unil.ch .

• Neuroscience
• Social Behavior
• Neuronal Circuits
• +۳ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Sophie Sanchez is an Associate Professor at Uppsala University's Department of Organismal Biology, specializing in Evolution and Development. Her research focuses on vertebrate evolution, using advanced imaging techniques like synchrotron microtomography to study fossilized anatomy and developmental processes. She has contributed significantly to understanding sensory organ evolution in jawed vertebrates, early tetrapod development, and the structural adaptations of ancient fish. Key work includes studies on placoderms, osteostracans, and the molecular bases of evolutionary innovations. Her findings bridge paleontology with developmental biology, employing cutting-edge microscopy to reveal hidden biological details in fossils. Publications highlight her expertise in fossil musculature, bone histology, and genomic evolution, with high-impact contributions to journals like Nature and Science . Collaborative projects involve global teams analyzing Devonian and Permian vertebrates, emphasizing interdisciplinary approaches to evolutionary questions.

• Vertebrate Paleontology
• Evolutionary Developmental Biology
• Comparative Anatomy
• +۳ مورد دیگر

Dr. Ting-Feng Lin is an Assistant Professor at the Cell Biology, Neurobiology and Biophysics department within the Faculty of Science at Utrecht University, Netherlands. His research focuses on understanding the mechanisms of learning and memory formation in the cerebellum, particularly how synaptic and intrinsic plasticity mechanisms coordinate to regulate neuronal signaling and behavior. He employs advanced microscopy, optogenetic, and chemogenetic techniques in transparent zebrafish models to study these processes in vivo, with implications for neurodevelopmental disorders like autism spectrum disorder (ASD) and schizophrenia. 2025: Assistant Professor, Utrecht University 2019-2025: Postdoctoral Researcher, University of Chicago 2015-2019: PhD in Neuroscience, Neuroscience Center Zurich (ZNZ) 2010-2014: MS in Physiology, National Taiwan University 2006-2010: BS in Sports Medicine, China Medical University His work investigates how sensory experiences shape cerebellar processing during development, focusing on climbing fiber pathways and their role in sensory prediction errors. His group also studies the interaction between synaptic, intrinsic, and structural plasticity mechanisms in neural circuits, using zebrafish models with genetic modifications (e.g., Grid2 knockout) to model human neurological conditions. Dr. Lin has received scientific recognition including the SfN Trainee Professional Development Award for his work on Purkinje cell plasticity and the JNS Meeting Award for research on parallel fiber ramping activity and LTD. His publications span topics from cerebellar plasticity to voltage-gated K+ channel dynamics, reflecting his interdisciplinary approach to neurobiology.

• Neuroscience
• Neurobiology
• Cerebellar Plasticity
• +۷ مورد دیگر

Raphael Franzini serves as Associate Professor of Medicinal Chemistry at the University of Utah, actively contributing to the Biological Chemistry PhD Program. His research pioneers innovative chemical approaches for therapeutic development, with dual focus on DNA-encoded library technologies and bioorthogonal drug delivery systems. His educational foundation includes an M.S. from the Swiss Federal Institute of Technology (Lausanne) and a Ph.D. from Stanford University. This training underpins his group's multidisciplinary methodology combining organic synthesis, bioconjugation, computational modeling, and advanced imaging techniques. Dr. Franzini's research program centers on two transformative areas: First, advancing DNA-encoded library screening through computational integration to identify leads for challenging targets like Tankyrase and Sirtuin 6, with recent work addressing false negatives in machine learning prediction. Second, developing novel bioorthogonal release chemistry using isonitrile-tetrazine reactions for spatiotemporally controlled drug activation, validated in zebrafish models. His group emphasizes both technological innovation and therapeutic translation, with chemistry designed to minimize off-target effects in solid tumors. Analysis of his 15 most recent publications reveals escalating integration of computational methods with experimental library screening, alongside refinement of bioorthogonal release kinetics. The work spans chemical biology, medicinal chemistry, and pharmaceutical sciences, with growing emphasis on machine learning for library data interpretation and in vivo validation of drug-release systems. Dr. Franzini maintains an active research laboratory that provides comprehensive training in cutting-edge drug discovery methodologies. His group culture prioritizes both scientific innovation and researcher development, with projects spanning from fundamental reaction kinetics to therapeutic applications. The lab's infrastructure supports organic synthesis, molecular imaging, and computational analysis for advancing precision therapeutics.

• Drug Discovery
• Medicinal Chemistry
• Bioorthogonal Chemistry
• +۳ مورد دیگر

Donald Rio holds the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences and is a Professor of Biochemistry, Biophysics, and Structural Biology. He is affiliated with the Division of Biochemistry and Molecular Biology and the Center for Integrative Genetics. His lab focuses on nucleic acid transactions, including transposable element mobilization (P elements) and RNA binding protein mechanisms controlling alternative splicing. Research highlights include studies on THAP9 proteins in humans/zebrafish, cryo-EM structural analysis of transposase-DNA complexes, and splicing regulation in neurodegenerative diseases like ALS and Parkinson’s. His work combines biochemical, genetic, and computational approaches, including the development of the Junction Usage Model (JUM) for splicing analysis. Research interests span transposition mechanisms linked to HIV integration, immune system recombination, and evolutionary genome dynamics. His team investigates how RNA binding proteins like hnRNPA1 influence splicing in disease contexts, with projects involving CRISPR-based models and patient RNA-seq data analysis. Collaborations include studies on splicing accuracy across tissues and age, and the impact of splicing defects in neurodegenerative disorders. Key awards include the Goldman Chair. His lab’s contributions bridge fundamental molecular mechanisms with translational applications in genetic disease modeling and drug discovery. Recent work focuses on isogenic stem cell models (iSCORE-PD) for Parkinson’s research and structural biology insights into transposase function. Grants and projects involve NIH funding for ALS splicing studies and collaborations with institutions like the Buck Institute. His lab actively publishes in top journals such as Genome Research , PNAS , and Nature , with a strong emphasis on cryo-EM and bioinformatic methods.

• Nucleic Acid Transactions
• Transposable Elements
• RNA Binding Proteins
• +۳ مورد دیگر

Dr. Markus Brinkmann is an Associate Professor in the School of Environment and Sustainability at the University of Saskatchewan, Canada, and Director of the Toxicology Centre. He holds the Centennial Enhancement Chair in Mechanistic Environmental Toxicology. His research focuses on exposure and risk assessment modeling, toxicokinetic modeling, and aquatic ecotoxicology, with an emphasis on understanding contaminant effects under realistic environmental conditions. Affiliations: Associate Professor, University of Saskatchewan Director, Toxicology Centre Member, Global Water Futures Program Member, Global Institute for Water Security Education: Ph.D. (Biology) - RWTH Aachen University, Germany (2015) M.Sc. (Ecotoxicology) - RWTH Aachen University, Germany (2011) B.Sc. (Biology) - RWTH Aachen University, Germany (2009) Research Interests: Dr. Brinkmann develops computational models to predict contaminant uptake, effects, and cross-species extrapolation. His work integrates toxicology, environmental chemistry, and hydrology to address challenges like flood-related contaminant remobilization and dioxin-like compound toxicity. Key areas include: Mechanistic toxicology of emerging contaminants (e.g., 6PPD-quinone, PFAS alternatives) Sediment toxicity and bioavailability Wastewater surveillance for public health monitoring Grant Highlights: Global Water Futures Program (2018-2023): Hydrological-exposure models for environmental risk assessment Genome Canada (2016-2020): EcoToxChip for chemical prioritization Banting Postdoctoral Fellowship (2016-2018) Awards: Friedrich-Wilhelm-Award (2016) SETAC GLB Young Scientists Award (2016 PhD, 2012 MSc) Borchers medal (2016) Leadership: He advises on strategic research partnerships between Canada and Germany and collaborates globally on projects like the EcoToxChip and Project House Water . His work bridges academic research with practical environmental management solutions.

• Exposure and risk assessment modelling
• Toxicokinetic modelling
• Aquatic ecotoxicology
• +۳ مورد دیگر

Xenophon Papademetris is a Professor of Biomedical Informatics & Data Science and Radiology & Biomedical Imaging at Yale School of Medicine. He serves as Associate Director of Biomedical Imaging Data Sciences at Yale Biomedical Imaging Institute and directs the Medical Software and Medical Artificial Intelligence Certificate Program. PhD in Electrical and Information Sciences from Yale University (2000) BA from Cambridge University (1994) Postdoctoral Fellowship at Yale University (2002) His research focuses on medical image analysis, machine learning, and biomedical software development. He has developed tools like BioImage Suite Web and contributed to standards committees at the Association for the Advancement of Medical Instrumentation (AAMI). His work spans modalities including MRI, CT, PET, and optical imaging. Recent publications emphasize neuroimaging analysis, explainable AI in healthcare, and multimodal data integration across species. He leads NIH-funded research under the BRAIN Initiative (R24 MH114805) and has authored a textbook on Medical Software published by Cambridge University Press. IEEE Senior Member Yale Brown-Coxe Postdoctoral Fellowship Harding Bliss Prize for Excellence in Engineering He directs the BioImage Suite Project, creating web-based image analysis tools using JavaScript and WebAssembly. His teaching includes both academic courses and a Coursera program on Medical Software with over 14,000 enrollments.

• Medical Image Analysis
• Machine Learning
• Biomedical Software Development
• +۷ مورد دیگر

Chris B. Schaffer is a Professor in the Meinig School of Biomedical Engineering at Cornell University, specializing in developing advanced optical techniques to study neurovascular dynamics in neurological diseases. His lab focuses on Alzheimer’s disease mechanisms, leveraging multiphoton microscopy and in vivo imaging to explore capillary stalling, cerebral blood flow deficits, and their cognitive impacts. He holds a Ph.D. in Physics from Harvard University and postdoctoral training in neuroscience at UC San Diego. Research interests include biomedical imaging instrumentation, neurodegenerative disease modeling, and science education innovation. Awards include AAAS Fellowship (2021), AIMBE Fellowship (2019), and multiple teaching accolades. His work bridges engineering and medicine, with contributions to spinal cord injury studies, epilepsy, and vascular contributions to dementia (VCID). Notable discoveries include identifying neutrophil-induced capillary stalls as a key Alzheimer’s disease mechanism and demonstrating cerebral blood flow improvements can restore memory in mouse models. His lab also develops educational tools emphasizing science as a discovery process, used in K-12 and university settings.

• Biomedical Imaging and Instrumentation
• Bioengineering
• Neuroscience
• +۳ مورد دیگر

Ruben Portugues is a Professor of Brain Circuit Function and Dysfunction at the Institute of Neuroscience, Technical University of Munich (TUM). He is a full member of the Graduate School of Systemic Neurosciences (GSN), an associate and advisory board member of the Munich Center for Neurosciences (MCN), and leads a research group focused on understanding the neural basis of behavior. His lab uses larval zebrafish as a model organism to investigate sensorimotor control, decision-making, and motor learning through whole-brain imaging and circuit analysis. His research interests lie at the intersection of systems neuroscience and behavior. He investigates how brain circuits process sensory information, integrate it with motor output, and enable adaptive and flexible behavior. Key areas include the function of the cerebellum, heading direction networks, sensorimotor transformations, and the neural mechanisms of decision-making. His lab employs cutting-edge techniques including custom-built microscopes, behavioral assays, and computational analysis. The recent publications and preprints from his lab demonstrate a strong trend in decoding distributed neural circuits underlying navigation and decision-making in zebrafish. There is a clear focus on identifying specific brain regions (e.g., interpeduncular nucleus, cerebellum) and cell types involved in processing visual, motor, and spatial information. The work increasingly emphasizes whole-brain functional imaging and the emergence of cognitive-like representations such as allocentric heading direction. FENS-Kavli Network of Excellence (FKNE) PhD Thesis Prize (awarded to student Luigi Petrucco) Ruben Portugues actively mentors PhD students, including current advisees Luigi Petrucco, Ot Prat, and Shuhong Huang, and has successfully graduated Dr. Elena Dragomir and Dr. Vilim Štih. His lab engages in extensive collaborations, hosts visiting researchers, participates in teaching (e.g., CSHL Imaging Course, Cajal Course), and secures resources for advanced research. The lab is known for building its own microscopes and software, fostering technical innovation. The Portugues Lab operates as a dynamic, interdisciplinary team that combines experimental neuroscience with computational and engineering approaches. They regularly hold retreats, participate in scientific events, and contribute to community initiatives like the Munich Brain Day. The lab is preparing to relocate to the Department of Neurobiology and Behavior at Cornell University, marking a new phase in its research trajectory.

• Neuroscience
• Systems Neuroscience
• Behavioral Neuroscience
• +۷ مورد دیگر

Miriam Diamond is a Professor at the Department of Earth Sciences and School of the Environment, University of Toronto. She holds cross-appointments in Chemical Engineering, Dalla Lana School of Public Health, and Physical & Environmental Sciences. PhD in Chemical Engineering (University of Toronto, 1990) MSc in Mining Engineering (Queen’s University, 1984) MSc in Zoology (University of Alberta, 1980) Her research focuses on chemical contaminant fate, transport, and exposure in indoor and urban environments, Arctic regions, and Great Lakes systems. She develops mathematical models , passive sampling methods , and policy frameworks to address pollution from flame retardants, phthalates, PFAS, and microplastics. Recent publications highlight microplastic extraction techniques , sleeping children’s exposure , and polymeric flame retardant risks . Key awards include the Royal Society of Canada Fellowship and 2025 President’s Impact Award . She supervises PhD candidates Anna Shalin , Lin Boynton , and others. Her policy contributions include serving on the Canadian Chemical Management Plan Science Committee and co-chairing the Earth Commissioner initiative.

• Environmental Chemistry
• Pollution & Air Quality
• Chemical Contaminants
• +۶ مورد دیگر