جست‌وجوی استاد و پژوهشگر

• Mood Disorders
• Depression
• Bipolar Disorder
• +۴ مورد دیگر

Todd D. Gould is a Professor in the Department of Psychiatry at the University of Maryland School of Medicine, holding secondary appointments in Neurobiology and Pharmacology. His research laboratory investigates mood disorder pathophysiology and mechanisms of psychiatric medications using multidisciplinary approaches. Education: MD from the University of Virginia Postdoctoral fellowship at the National Institute of Mental Health Laboratory of Molecular Pathophysiology and Experimental Therapeutics Research Focus: Dr. Gould's work centers on understanding how mood stabilizers and antidepressants like lithium and ketamine exert their therapeutic effects, with particular emphasis on ketamine metabolites such as (2R,6R)-hydroxynorketamine. His laboratory employs genetic, pharmacological, biochemical, electroencephalographic, and behavioral methodologies to develop improved animal models for psychiatry and investigate functional consequences of mood disorder susceptibility genes. Key research areas include Depression, Bipolar Disorder, Antidepressant Pharmacology, and synaptic plasticity mechanisms. Analysis of his recent publications (2023-2025) reveals a dominant focus on ketamine's metabolites as rapid-acting antidepressants, exploring their unique synaptic effects independent of NMDA receptor blockade. His work increasingly examines estradiol signaling in stress susceptibility and depression pathophysiology, particularly in male models, while advancing hydroxynorketamine's clinical translation through pharmacokinetic and safety studies. Laboratory: Dr. Gould directs the Gould Lab (www.gouldlab.org), which maintains active collaborations with clinical research groups to bridge translational neuroscience and psychiatric treatment development.

• Neuropharmacology
• Neuroscience
• Neurodegenerative Diseases
• +۸ مورد دیگر

Professor Keith Murphy is a leading academic at University College Dublin , affiliated with the School of Biomolecular and Biomedical Science and the Conway Institute . As head of the UCD Neurotherapeutics Research Group , he pioneers work on drug targets for neurological disorders. Professor of Neuropharmacology (2018–present) Co-Director, UCD Centre for Applied Neuroscience (2015–present) Theme Leader for Neuroscience Research (2011–present) His research spans drug addiction , schizophrenia , multiple sclerosis , and memory consolidation , utilizing animal models , in vivo gene editing , and proteomic analysis . Recent work on cocaine-induced neurodevelopmental damage and midkine's role in memory demonstrates his focus on synaptic plasticity mechanisms. Key scientific contributions include: 2006: Rafaelsen Scholarship for neuropharmacology research 2016: Discovery of REST as hypoxia-responsive repressor 2025: Groundbreaking prenatal cocaine organoid study As an educator , he coordinated modules like Advanced CNS Pharmacology and Professional Career Development , mentoring future biomedical scientists. Current grants include SFI funding (2024–2027) for GDF-15/GFRAL signaling research in neuroprotection.

Scott Haydn Soderlingمشاهده پروفایل

استاد

• Synaptic Biology
• Neurogenetics
• Neurodevelopmental Disorders
• +۴ مورد دیگر

Scott Haydn Soderling is the George Barth Geller Distinguished Professor of Molecular Biology and Chair of the Department of Cell Biology at Duke University . He holds concurrent appointments in Neurobiology and is a member of the Duke Cancer Institute and Duke Institute for Brain Sciences. Ph.D. from University of Washington (1999) Research Interests focus on synaptic biology, neurogenetics, and cytoskeletal dynamics in neurodevelopmental disorders. His work bridges molecular mechanisms of synaptic plasticity with translational studies of conditions like autism, epilepsy-aphasia syndrome, and schizophrenia. Recent Publications highlight tripartite synaptomics, actin regulation in synapses, and chemico-genetic tools to map astrocyte-neuron interactions. Key themes include: Synaptic proteomics in neurological diseases Ciliary signaling pathways WASHC4 and lysosomal dysfunction CRISPR-based cell fate engineering Scientific Awards include Duke University's 2020 University Distinguished Professorship and funding from the Chan Zuckerberg Initiative , National Institutes of Health , and HHMI . Grants (2024-2029) cover topics like neurobiology training, chromatin dysregulation in neurodevelopmental disorders, and proteomic analysis of presynaptic physiology. He mentors programs in biomedical sciences and neuroscience.

Dimitri Michael Kullmannمشاهده پروفایل

استاد

• Synaptic transmission
• Neuronal circuit excitability
• Epilepsy mechanisms
• +۷ مورد دیگر

Dimitri Michael Kullmann serves as Professor of Neurology at University College London within the Queen Square Institute of Neurology, specifically in the Research Department of Epilepsy. His distinguished career spans over three decades since establishing his laboratory at the Institute of Neurology in 1992, following clinical training at St Thomas' Hospital and postdoctoral research with Roger Nicoll at UCSF. His educational background includes a Bachelor of Arts in Physiological Sciences from Oxford University (1979), a Doctor of Philosophy from Oxford (1984), and a Bachelor of Medicine/Bachelor of Surgery from the University of London (1986). He has held significant positions including MRC Senior Clinical Fellow (1997-2007) and MRC Clinician Scientist Fellow (1992-1997). Fellow of the Royal Society (2018) Fellow of the Academy of Medical Sciences Fellow of the Royal College of Physicians Member of the Academia Europaea Kullmann's research focuses on fundamental mechanisms of synaptic transmission, computational properties of neuronal circuits, and alterations in neuronal excitability in epilepsy. His laboratory has made landmark discoveries including silent synapses, glutamate spillover, presynaptic GABAA receptors in the cortex, and human epilepsy caused by K+ and Ca2+ channel mutations. He has pioneered several gene therapy approaches for focal epilepsy, some of which are being prepared for clinical translation. His publication record demonstrates consistent high-impact research across neuroscience, neurology, and molecular medicine, with recent work spanning from basic synaptic mechanisms to clinical applications for epilepsy treatment. His 2024-2025 publications reveal a strong focus on gene therapy for epilepsy, neural circuit dynamics, channelopathies, and innovative neurotechnologies. American Epilepsy Society Basic Science Research Prize (2023) Baly Medal from the Royal College of Physicians (2017) University Gold Medal from London University (1986) Kullmann actively supervises PhD students funded by Wellcome and MRC, and lectures on MSc courses at the Institute of Neurology and to undergraduate Neuroscience students at UCL. His collaborative network includes researchers such as Michael Hanna, Henry Houlden, James Jepson, and Matthew Walker, reflecting the interdisciplinary nature of his work bridging basic neuroscience and clinical neurology.

Gulcan Akgulمشاهده پروفایل

استادیار

• Neuroscience
• Developmental Neuroscience
• Cellular Neuroscience
• +۲ مورد دیگر

Gulcan Akgul serves as Assistant Professor of Research in Neuroscience at the Brain and Mind Research Institute, Weill Cornell Medical College since 2021, contributing to Cornell University's neuroscience enterprise through molecular and cellular investigations of neural circuit development. Her academic preparation includes: Ph.D. from State University of New York at Stony Brook (2012) B.S. from Bilkent University, Turkey (2004) Dr. Akgul's research centers on inhibitory interneuron biology, with sustained investigation into parvalbumin-expressing subtypes across cortical and hippocampal regions. Her work examines chemokine-mediated differentiation (Cxcl14), AMPA receptor dynamics, microglial-synaptic interactions, and pathological mechanisms in neurodevelopmental disorders like lissencephaly. This multidisciplinary approach bridges molecular neuroscience, neural development, and systems-level network function through electrophysiological, genetic, and anatomical methodologies. Analysis of her publication history (2010-2024) reveals three dominant research trajectories: (1) developmental specification of cortical interneuron subtypes, (2) synaptic regulation by glial and immune mechanisms, and (3) pathological hyperexcitability in neurodevelopmental disease models. Her work consistently appears in high-impact neuroscience journals including Cell Reports , eLife , and Journal of Neurophysiology , demonstrating methodological rigor in cellular and circuit-level analyses. As a core member of the Brain and Mind Research Institute, Dr. Akgul operates within Weill Cornell Medical College's collaborative neuroscience ecosystem, utilizing institutional resources for advanced molecular and electrophysiological investigations of neural circuit formation and function.

Uri Asheryمشاهده پروفایل

استاد

• Neuroscience
• Molecular Neuroscience
• Neurodegenerative Diseases
• +۵ مورد دیگر

Prof. Uri Ashery is a Professor at the Sagol School of Neuroscience, Tel Aviv University, where he leads research on molecular mechanisms of learning and memory and their links to neurodegenerative diseases such as Alzheimer's and Parkinson's. His work spans molecular neuroscience, synaptic plasticity, and neurodegenerative disease mechanisms, with specific focus on hippocampal mossy fiber synapses, hyperbaric oxygen therapy effects in Alzheimer's models, and alpha-synuclein aggregation in Parkinson's disease. The laboratory employs multidisciplinary methodologies including electrophysiology, super-resolution microscopy (dSTORM/STED), molecular biology, animal behavior studies, and computational modeling to correlate molecular changes with synaptic function. Recent publications demonstrate consistent investigation into protein aggregation pathologies in Parkinson's disease, neuroinflammatory mechanisms in Alzheimer's models, and fundamental synaptic transmission processes involving proteins like Tomosyn, Munc13-1, and DOC2B. Key themes include therapeutic interventions for neurodegeneration and molecular underpinnings of synaptic plasticity. No scientific awards are documented in the provided materials. Details regarding student supervision and research grant funding are not specified in the available information. The research laboratory operates as a multidisciplinary team utilizing advanced techniques including multi-electrode arrays, super-resolution imaging, and transgenic animal models to investigate synaptic dysfunction in neurodegenerative conditions, with emphasis on identifying early biomarkers and developing therapeutic strategies for Parkinson's and Alzheimer's diseases.

Johanne Egge Rinholmمشاهده پروفایل

دانشیار

• Neuroscience
• Neurophysiology
• Cell Biology
• +۳ مورد دیگر

Johanne Egge Rinholm is an Associate Professor at the University of Oslo's Section of Physiology. Her research focuses on oligodendrocyte biology, myelin physiology, and metabolic regulation in the nervous system, particularly investigating lactate signaling, mitochondrial dynamics, and oxidative stress. Institution: University of Oslo Academic Rank: Associate Professor Research Interests include: brain metabolism, ischemic brain injury, mitochondrial function in oligodendrocytes, neuroglial interactions, and lactate receptor (HCAR1) mechanisms. She has pioneered studies on lactate's role in neuroprotection and angiogenesis. Recent Publications highlight her work on: neurodevelopmental epigenetics (2023), HCAR1-mediated microglial activation (2022), mitochondrial dysfunction in metabolic disorders (2021), and long-standing expertise in oligodendrocyte physiology dating to 2007. Teaching includes courses in Molecular Medicine and Physiology (MED1100/MED2200) covering membrane transport, reproduction, and neuroenergetics. Research Groups : Active member of the Oligodendrocyte Group, contributing to projects on transplanted brain organoids and metabolic regulation in white matter.

Svend Davangerمشاهده پروفایل

استاد

• Brain and nervous system
• Synapses
• Synaptic plasticity
• +۷ مورد دیگر

Svend Davanger is a Professor at the Section of Anatomy, Department of Molecular Medicine, Faculty of Medicine, University of Oslo. He has held this position since 2008, following previous appointments as Associate Professor at the Department of Anatomy, University of Oslo (2003-2008) and at the Department of Anatomy and Cell Biology, University of Bergen (1997-2003). His research focuses on the neural mechanisms underlying brain function, with particular emphasis on synaptic organization and plasticity in the hippocampus. Davanger received his Cand. med. degree from the University of Oslo in 1988 and his Dr. med. in 1995. He completed a postdoctoral fellowship at Stanford University's Department of Molecular and Cellular Physiology (1995-1997). As a licensed physician since 1995, he has clinical experience including work at the Specialist Hospital for Epilepsy, Rikshospitalet/Oslo University Hospital (2001-2003). His primary research investigates synaptic plasticity - the fundamental mechanism for learning and memory. He examines how synapses change under various conditions including stress, epilepsy, and meditation practices. His work focuses on specific proteins like Arc, AMPA and NMDA receptors, and SNARE complex components. A distinctive aspect of his research program bridges basic neuroscience with contemplative practices, particularly studying the neural correlates of meditation. His laboratory employs advanced techniques including electron microscopy, immunocytochemistry, and animal models to elucidate molecular mechanisms of synaptic communication. Analysis of his recent publications (2016-2025) reveals a consistent focus on molecular and cellular mechanisms of synaptic function, with progression from basic mechanisms to alterations in disease states. A notable trend is the increasing investigation of meditation's effects on brain structure, culminating in large-scale collaborative efforts like the ENIGMA-Meditation consortium. His work demonstrates how specific proteins regulate synaptic communication and plasticity in both normal and pathological conditions. Professor Davanger actively collaborates with researchers worldwide, including Jeremy Henley at the University of Bristol, Nanyin Zhang at Penn State University, and Andrew Bean at the University of Texas. His research is organized through several key projects conducted within the Brain Plasticity and Synaptic Plasticity research groups at the University of Oslo. As an educator, Davanger teaches MED1100 (Medical Studies, Module 1) and MED2200 (Medical Studies, Module 2) at the University of Oslo. His clinical background in epilepsy and neuroscience informs his teaching approach, providing students with both theoretical knowledge and practical clinical perspectives on neurological function.

Suzanne Paradisمشاهده پروفایل

استاد

• Synapse Development
• Neural Circuits
• Neurological Disorders
• +۶ مورد دیگر

Suzanne Paradis is a Professor of Biology at Brandeis University and an affiliated faculty member of the Neuroscience Program and the Benjamin and Mae Volen National Center for Complex Systems. Her research focuses on defining the molecular and genetic programs underlying synapse development and neuronal connectivity, particularly in relation to neurological disorders such as epilepsy and autism spectrum disorders. Education: Ph.D., Harvard University B.A., Cornell University Research Interests: The Paradis Lab investigates molecular mechanisms of synapse formation and circuit connectivity using biochemical, molecular, genetic, and electrophysiological approaches. Key areas include the roles of genes like Rem2 and Sema4D in regulating dendritic morphology, inhibitory synapses, and seizure suppression. Current work explores translating these findings into therapies for acute seizures. Selected Research Trends: Her recent publications highlight the interplay between semaphorins, GTPases, and kinases in synapse development, with a focus on rapid protein-induced synaptogenesis and its therapeutic potential for neurological disorders. Scientific Awards: Thomas A. King Faculty Ally Award (2022) Sloan Research Fellow (2009-2011) Smith Family Award (2008-2011) Basil O'Connor Starter Scholar (2009-2011) Career Development Award, Society for Neuroscience (2007) Grants and Collaborations: Her work has been supported by grants from the Alfred P. Sloan Foundation, Smith Family Foundation, March of Dimes, and Society for Neuroscience. She collaborates with researchers in neurophysiology, computational modeling, and translational neuroscience. Lab Ethos: The Paradis Lab emphasizes a diverse and inclusive environment, fostering teamwork and knowledge-sharing to advance understanding of neural network mis-wiring in disease states.

• Neuroscience
• Memory Consolidation
• Hippocampus
• +۷ مورد دیگر

Zhang Xiaomin is an Assistant Professor of Neuroscience at the Brain Research Institute, University of Zurich. Her research focuses on understanding the cellular and circuitry mechanisms underlying episodic memory consolidation in the hippocampus, with particular relevance to early-onset Alzheimer's disease. She employs advanced in vivo electrophysiological recordings and optical tools to investigate single-neuron dynamics, neuronal population coding properties, and the role of neuromodulation during spatial memory consolidation. Her educational background includes: Bachelor's degree in Biomedicine from China Master's degree in Neuroscience from China Ph.D. from University of Heidelberg, Germany under Prof. Andreas Draguhn Postdoctoral fellowship at Institute of Science and Technology, Austria under Prof. Peter Jonas Dr. Zhang's research primarily investigates how episodic memories, which initially are fragile, become consolidated for long-term retention. She has established in vivo whole-cell patch-clamp recording techniques in head-fixed behaving animals to study memory consolidation mechanisms. Her work bridges cellular neuroscience with cognitive function, focusing on how disruptions in these processes contribute to Alzheimer's disease pathology. The laboratory employs cutting-edge methodologies including advanced electrophysiology, optical tools, and computational approaches to understand neural coding during memory formation. Analysis of her publication record reveals a strong focus on hippocampal function, particularly dentate gyrus circuitry and granule cell dynamics. Her research trajectory shows progression from basic cellular mechanisms to more complex network-level questions, with increasing emphasis on computational approaches and disease models. The publications demonstrate expertise in both experimental neuroscience and computational analysis, with significant contributions to understanding how neural circuits process spatial information and consolidate memories. Her scientific achievements have been recognized through prestigious awards: SNSF Prima Fellowship Synapsis Foundation Career Development Award Dr. Zhang leads the Laboratory of Memory Consolidation at the University of Zurich, where she mentors a diverse research team including multiple PhD students and research assistants. Her group continues to investigate the neuronal mechanisms underlying impaired episodic memory formation, with the ultimate goal of identifying potential therapeutic targets for Alzheimer's disease and related memory disorders. The laboratory maintains active collaborations with other neuroscience research groups at the Brain Research Institute and beyond.

• Neurodevelopment
• Inhibitory Synapse Formation
• Autism Spectrum Disorders
• +۵ مورد دیگر

Rochelle Hines, Ph.D. , is an Associate Professor in the Department of Psychology at the University of Nevada, Las Vegas (UNLV). Her laboratory investigates how inhibitory synapses form, stabilize, and malfunction during brain development, with the overarching goal of identifying novel therapeutic avenues for autism, schizophrenia, and developmental epilepsies. Education Ph.D. in Neuroscience, University of British Columbia, Vancouver, Canada (2009) Postdoctoral Fellowship, Tufts University School of Medicine, Boston, MA (2015) Research Interests Dr. Hines’s research integrates molecular genetics, biochemistry, high-resolution microscopy, behavioral phenotyping, and electrophysiology to dissect the mechanisms governing inhibitory synapse maturation. By manipulating key synaptic proteins in mouse models, her team interrogates how disruptions in inhibitory signaling contribute to neurodevelopmental disorders. Core themes include: Molecular scaffolding of GABAergic synapses via collybistin and neuroligin-2 Functional specialization of GABA(A) receptor subunits in cortical and hippocampal circuits Translational biomarkers and therapeutic targets for epilepsy and autism Publication Trends Across 38 peer-reviewed articles since 2006, Dr. Hines’s work has progressed from fundamental discoveries in synaptic protein trafficking to preclinical evaluations of pharmacological modulators (e.g., TSPO ligands, micronized caffeine). Recent high-impact studies (2021–2025) emphasize multi-system analyses combining EEG, behavioral, and molecular readouts to bridge cellular mechanisms with circuit-level dysfunction. Laboratory & Collaborations The Hines Group at UNLV houses state-of-the-art facilities for confocal and electron microscopy, in vivo EEG/EMG recordings, and mouse behavioral testing. Active collaborations span Tufts University, University of British Columbia, and international consortia focused on neurodevelopmental genomics and bio-electronic therapeutics. Funding & Grants While specific grant identifiers are not listed, the consistent publication output and patent filings (e.g., therapeutic compounds for neurodevelopmental disorders, 2025) indicate sustained extramural funding from NIH, NSF, and private foundations.

• Neuroscience
• Synaptic Plasticity
• Ion Channels
• +۳ مورد دیگر

Prof. Ryuichi Shigemoto is a Principal Investigator leading the SINCHAIS project (2016-2021), funded by the European Research Council's Advanced Grant under Horizon 2020. The project focuses on visualizing single channel subunit composition in neurons using advanced electron microscopy techniques, aiming to uncover mechanisms linking synaptic plasticity to behavior. Research Interests: Ion channel subunit composition, synaptic efficacy regulation, optogenetic stimulation, electron tomography, and phosphoinositide-mediated ion channel regulation. Team Members: Pradeep Bhandari (PhD Student): EM localization of calcium channels Kohgaku Eguchi (Postdoc): EM localization and function of calcium channels Felipe Fredes (Postdoc): AMPA receptor subunit composition in hippocampal synapses Marijo Jevtic (PhD Student): Development of EM-tag labeling methods Shigekazu Tabata (Postdoc): Reactive-tag system for NMDA receptor analysis

Anja Meissnerمشاهده پروفایل

دانشیار

• Cardiovascular Disease
• Vascular Biology
• Neurodegeneration
• +۶ مورد دیگر

Anja Meissner is a Senior Lecturer and Associate Professor in Biomedical Engineering at Lund University, Sweden. She serves as Principal Investigator at the Wallenberg Centre for Molecular Medicine (WCMM) and contributes to multidisciplinary research on Parkinson's disease through MultiPark. Her work focuses on sphingosine-1-phosphate (S1P) signaling in cardiovascular diseases, particularly hypertension, stroke, and heart failure. Role: Senior Lecturer & Associate Professor Institution: Lund University Department: Division for Biomedical Engineering Meissner's research explores: S1P signaling in vascular-immune interactions Mechanisms of hypertension and neurodegeneration Therapeutic targeting of CFTR and S1P pathways Sex-specific cardiovascular responses to dietary stressors Her recent publications demonstrate: Translational S1P research from experimental models to clinical applications Therapeutic strategies for reversing hypertension and heart failure complications Sex-based differences in vascular pathophysiology Novel connections between CFTR, S1P, and neuroinflammation Meissner coordinates research infrastructure at Life Science Microfluidics and organizes the WCMM Research School. Her work aligns with UN Sustainable Development Goals for cardiovascular health and neurodegenerative disease research.

Nelson Rebolaمشاهده پروفایل

پژوهشگر

• Neuroscience
• Neurophysiology
• Synaptic Transmission
• +۴ مورد دیگر

Nelson Rebola is a Junior Team Leader and Principal Investigator (PI) at the Paris Brain Institute (ICM), affiliated with CNRS. His research focuses on understanding how cellular and network mechanisms in the brain enable sensory perception and context-dependent processing. Education: Biochemistry (University of Lisbon, 2002), Biology (University of Coimbra, 2008). Rebola's work investigates the flexibility of sensory systems in varying behavioral contexts, such as wakefulness states, and how this adaptability underpins healthy brain function and disorders like schizophrenia and depression. His team employs a multidisciplinary approach, combining electrophysiology, two-photon imaging, optogenetics, and computational modeling in mouse models. Key research areas include: Synaptic transmission and calcium dynamics Neuronal circuit modulation in pathological states Context-dependent cortical processing Neurological disorder biomarkers Scientific contributions include seminal work on synaptic plasticity, NMDA receptor dynamics, and lipid-mediated potassium channel regulation. Awards include an EMBO Long-Term Fellowship. Candidates interested in joining his lab can contact him at nelson.rebola@icm-institute.org . Open positions are available for Master, PhD, and Postdoctoral researchers.

Jimcy Platholiمشاهده پروفایل

استادیار

• Neuroscience
• Neuroinflammation
• Alzheimer's Disease
• +۷ مورد دیگر

Jimcy Platholi is an Assistant Professor of Neuroscience at Weill Cornell Medical College, affiliated with the Brain and Mind Research Institute. Their research focuses on neuroinflammation in neurodegenerative diseases, synaptic transmission mechanisms, and protein phosphatase regulation. Ph.D. (2008) and B.A. (1997) from Weill Cornell Graduate School of Medical Sciences M.A. (1999) from New York University Current research examines neuroinflammatory processes in perimenopausal Alzheimer's disease models , with a focus on hippocampal region-specific alterations. Earlier work investigated anesthetic effects on sodium channels (Na v 1.3) and synaptic spine dynamics. Recent publications demonstrate expertise in neurodegenerative mechanisms , with emphasis on Alzheimer's disease , cerebral amyloid angiopathy , and neuroinflammatory biomarkers . Earlier studies explored protein phosphatase regulation and neurogenetic pathways in auditory development and schizophrenia. Active as a Principal Investigator since 2019, they have secured multiple NIH grants for research on synaptic mechanisms of general anesthetics and neuroinflammatory processes in neurodegenerative diseases.