Uri Ashery

Prof. Uri Ashery is a Professor at the Sagol School of Neuroscience, Tel Aviv University, where he leads research on molecular mechanisms of learning and memory and their links to neurodegenerative diseases such as Alzheimer's and Parkinson's.

His work spans molecular neuroscience, synaptic plasticity, and neurodegenerative disease mechanisms, with specific focus on hippocampal mossy fiber synapses, hyperbaric oxygen therapy effects in Alzheimer's models, and alpha-synuclein aggregation in Parkinson's disease. The laboratory employs multidisciplinary methodologies including electrophysiology, super-resolution microscopy (dSTORM/STED), molecular biology, animal behavior studies, and computational modeling to correlate molecular changes with synaptic function.

Recent publications demonstrate consistent investigation into protein aggregation pathologies in Parkinson's disease, neuroinflammatory mechanisms in Alzheimer's models, and fundamental synaptic transmission processes involving proteins like Tomosyn, Munc13-1, and DOC2B. Key themes include therapeutic interventions for neurodegeneration and molecular underpinnings of synaptic plasticity.

No scientific awards are documented in the provided materials.

Details regarding student supervision and research grant funding are not specified in the available information.

The research laboratory operates as a multidisciplinary team utilizing advanced techniques including multi-electrode arrays, super-resolution imaging, and transgenic animal models to investigate synaptic dysfunction in neurodegenerative conditions, with emphasis on identifying early biomarkers and developing therapeutic strategies for Parkinson's and Alzheimer's diseases.