جست‌وجوی استاد و پژوهشگر

Scott Chandlerمشاهده پروفایل

استاد

• Neuroscience
• Neurophysiology
• Movement Disorders
• +۳ مورد دیگر

Scott Chandler is a Professor in the Department of Integrative Biology and Physiology at the University of California, Los Angeles (UCLA). His research focuses on understanding the central nervous system's control of rhythmic movements and neurodegenerative diseases like ALS. B.S., Neurobiology, University of California, Berkeley Ph.D., Physiology/Neurophysiology, University of California, Los Angeles (1979) Chandler's research explores how small brainstem neuronal networks generate rhythmic movements (e.g., mastication, respiration) and how ion channels contribute to these processes. His lab investigates early ALS-related neuronal dysfunction using transgenic mouse models, aiming to identify molecular targets for drug therapies. 2023 study on GABA inhibition and L-type calcium currents in ALS mouse jaw neurons 2020 work on single-cell RNA-seq in ALS brainstem analysis 2019 publications on resurgent sodium currents and circuit-specific ALS impairments 2015 studies on sensory neuron enrichment and membrane homeostasis in ALS 2007-2009 work on Kv1 channels and Nav1.6 sodium currents in trigeminal neurons Chandler's lab combines electrophysiological recordings, computational modeling, and bioinformatics to unravel the cellular mechanisms underlying movement control and neurodegeneration.

Alexander Pietrasمشاهده پروفایل

دانشیار

• Cancer Stem Cells
• Brain Tumors
• Therapeutic Resistance
• +۷ مورد دیگر

Alexander Pietras is an Associate Professor and Senior Lecturer at Lund University's Division of Translational Cancer Research within the Faculty of Medicine and Lund University Cancer Centre (LUCC). His research focuses on therapeutic resistance in glioblastoma multiforme (GBM) , aiming to identify strategies targeting cancer stem cells and microenvironmental control mechanisms . Research Highlights: Investigates radiation-resistant stem-like cells using mouse models and human glioma cultures. Studies hypoxia , DLK1 signaling , and CD44-HIF-2α interactions in tumor phenotypes. Develops novel therapeutic approaches for malignant brain tumors through microenvironmental targeting . Supervised Students: Rosberg, R. (2020–present): Dissertation on cell-cell interactions in glioma resistance. Pantazopoulou, V. (2017–2021): Dissertation on FIH-1 in GBM. Scientific Activities: Co-organized LUCC-CNS webinars on drug delivery and glioma recurrence (2024–2025). Presented at LUCC-SUHCCC Day (2024) on radiotherapy-induced microenvironmental changes .

Naoto Hoshiمشاهده پروفایل

دانشیار

• Neuroscience
• Molecular Biology
• Ion Channels
• +۵ مورد دیگر

Naoto Hoshi, PhD, is an Associate Professor in the Department of Physiology & Biophysics at the University of California, Irvine (UCI) School of Medicine. His research focuses on molecular mechanisms of ion channel regulation, particularly KCNQ (M-type) potassium channels, calmodulin dynamics, and kinase/phosphatase interactions. Research Themes: Neuronal excitability and epilepsy Protein phosphorylation in channel function Calmodulin and PIP2 signaling Modulation by endogenous compounds (e.g., DHEAS, hydrogen sulfide) His work has revealed how CK2 and PP1 anchored to KCNQ2 complexes dynamically regulate channel activity, impacting memory consolidation and seizure pathology. Collaborative studies span neurology, reproductive physiology, and cardiovascular research. Grants: R01 NS49119 (NIH/NINDS) T32 HD007430 (NIH/NICHD) R01 NS067288 (NIH/NINDS) Dr. Hoshi's lab employs advanced electrophysiology, molecular biology, and pharmacology to investigate channelopathies and develop novel neuromodulatory therapies.

• Neuroscience
• Physiology
• Cellular Neuroscience
• +۵ مورد دیگر

Professor Andrew Moorhouse serves as Professor of Physiology and Horizons Professor of Medical Sciences (Education Focused) at the School of Medical Sciences within the Faculty of Medicine and Health at the University of Sydney. His dual appointment reflects his significant contributions to both neuroscience research and physiology education. With an active research program spanning over two decades, Professor Moorhouse maintains strong international collaborations, particularly with Japanese research institutions as evidenced by his extensive publication record. Professor Moorhouse's research interests center on cellular and molecular neuroscience with particular emphasis on microglia-neuron interactions, ion channel physiology, and neural plasticity mechanisms. His work investigates how microglia modulate synaptic function, how astrocytes influence pain pathways, and the role of chloride transporters like KCC2 in neural circuit function. More recently, he has made substantial contributions to physiology education reform in Australia, leading multiple projects to establish consensus on core physiological concepts through the Delphi method. Analysis of his publication trends reveals a clear evolution from fundamental neuroscience research toward integrated approaches combining cellular mechanisms with systems-level physiology and educational frameworks. While his earlier work (2003-2015) focused primarily on ion channel biophysics and receptor physiology, his recent publications (2019-2024) demonstrate expanding interests in neural circuit function, pain mechanisms, and physiology education. His research consistently appears in high-impact journals including Nature Communications, Science Advances, and Journal of Neuroscience. Professor Moorhouse has been actively involved in physiology education reform in Australia, contributing to multiple collaborative papers on core concepts in physiology education. His work with Australian colleagues has systematically unpacked and validated fundamental physiological concepts including homeostasis, integration, cell-cell communication, and the structure-function relationship across various physiological systems. His research program demonstrates significant collaborative activity with both Australian and international colleagues, particularly from Japan. While specific grant information isn't provided in the available text, his extensive publication record across multiple high-impact journals suggests sustained research funding. Professor Moorhouse appears to work within a neuroscience research group focusing on glial cell function, neural plasticity, and pain mechanisms, with strong connections to both Australian physiology education networks and Japanese neuroscience laboratories.

Igor Vorobyovمشاهده پروفایل

استادیار

• Computational Biophysics
• Ion Channels
• GPCR Modeling
• +۲ مورد دیگر

Igor Vorobyov is Assistant Professor in Physiology and Membrane Biology at UC Davis. His computational lab studies drug interactions with ion channels (hERG, NaV1.5, CaV1.2) and GPCRs using molecular dynamics to predict drug-induced arrhythmias and develop neurocardiovascular simulators. Publications focus on β-adrenergic receptor dynamics, PIP2 regulation of potassium channels, and AlphaFold-enhanced hERG modeling.

Pablo Casillas-Espinosaمشاهده پروفایل

دانشیار

• Epilepsy Research
• Neurology
• Biomarkers
• +۶ مورد دیگر

Pablo Casillas-Espinosa is an Associate Professor (Research) in the Department of Neuroscience at Monash University's School of Translational Medicine and an NHMRC Early Career Fellow. He holds an MD from the University of Guadalajara, Mexico, and a PhD from the University of Melbourne. His research focuses on epilepsy biomarkers, disease-modifying therapies, and preclinical models of traumatic brain injury (TBI), stroke, and neurodegenerative disorders. He employs multi-omics and computational approaches to identify novel treatments, including stem cell and drug repurposing strategies. His work has led to one patent (PCT/US2017/000097) and ongoing clinical trials, such as the SELECT Trial evaluating sodium selenate for drug-resistant temporal lobe epilepsy. Key areas of expertise include biomarker discovery, post-traumatic epilepsy (PTE), and translational drug development. He has secured competitive grants and international awards, including the American Epilepsy Society Young Investigator Award (2016) and the ILAE Latin America Travel Grant (2020). He serves as Global Secretary of the Young Epilepsy Section of the International League Against Epilepsy (ILAE) and leads collaborations across multiple institutions. Research activities include over 50 publications and 17 projects, with a focus on harmonizing preclinical data, neuroimaging (MRI/DTI/PET), and advanced computational methods. His lab investigates genetic and molecular determinants of epilepsy, leveraging congenic rat strains and chronic animal models to understand epileptogenesis. Media coverage highlights breakthroughs like a potential new drug for brain trauma in epilepsy patients.

Brent Hillمشاهده پروفایل

استاد

• Cardiovascular Physiology
• Bone Biology
• Estrogen Effects on Vascular and Skeletal Systems
• +۳ مورد دیگر

Brent Hill, Ph.D., is a Professor and Chair of the Biology Department at the University of Central Arkansas (UCA). He joined UCA in 2003. His research focuses on the impact of female sex hormones, particularly estrogen, on cardiovascular and skeletal systems, including estrogen's effects on calcium regulatory proteins in vasculature and bone biophysical properties. He teaches courses such as Cardiovascular Physiology, Cell Biology, and Biology for General Education. Education: B.A., Biology, Luther College, 1993 M.S., Veterinary Physiology & Pharmacology, Iowa State University, 1995 Ph.D., Medical Physiology, University of Missouri, 2000 Research Interests: Dr. Hill’s work investigates how estrogen influences calcium-regulatory proteins in blood vessels and bone strength. Key questions include estrogen’s role in vascular calcium channel regulation and its effects on bone structure under conditions like simulated microgravity. His studies combine molecular biology, pharmacology, and biomechanical analyses. His publications highlight advancements in understanding estrogen’s non-genomic effects on coronary arteries and bone health. Dr. Hill is also an advocate for integrating physiology into undergraduate curricula, emphasizing hands-on teaching methods like the frog heart preparation for vascular studies.

• Electrophysiology
• f-MRI modeling
• Bioinformatics
• +۷ مورد دیگر

Dr. Keun Hang Yang is a Professor in the Department of Biological Sciences at Schmid College of Science and Technology, Chapman University. Her research focuses on electrophysiology, neuroscience, and pharmacology, with particular expertise in ion channel function and cannabinoid pharmacology. She maintains an active research program investigating the interactions between natural compounds, pharmaceuticals, and neuronal signaling pathways. Dr. Yang received her Bachelor of Science from Ewha Womans University, followed by a Master of Science and Ph.D. from George Mason University. Her educational background in biological sciences has provided the foundation for her interdisciplinary research approach that bridges molecular pharmacology, neuroscience, and computational biology. Dr. Yang's research interests span multiple domains of neuroscience and pharmacology. She specializes in electrophysiology techniques to study ion channel function, particularly focusing on ligand-gated and voltage-gated channels. Her work in cannabinoid pharmacology investigates how phytocannabinoids and endocannabinoids interact with neuronal receptors. She also applies computational approaches to model complex biological systems and has expertise in bioinformatics for analyzing large biological datasets. Additional research areas include the study of flavonoids and other natural compounds on neuronal function, neuropharmacology of pain and psychiatric disorders, and the relationship between environmental factors and health . Analysis of Dr. Yang's recent publications reveals a strong focus on ion channel pharmacology, particularly examining how cannabinoids, flavonoids, and other compounds modulate the function of ligand-gated ion channels such as nicotinic acetylcholine receptors and 5-HT3 receptors. Her work often employs Xenopus oocyte expression systems and mammalian cell models to investigate molecular mechanisms. A significant portion of her research examines drug interactions, particularly how natural compounds might influence the effects of pharmaceuticals. Her publication record demonstrates a consistent trajectory of high-impact research in neuropharmacology with increasing focus on translational applications. Dr. Yang actively collaborates with numerous researchers both within Chapman University and internationally. Her work often involves interdisciplinary teams combining expertise in molecular biology, electrophysiology, and computational modeling. While specific grant information isn't detailed in the available materials, her extensive publication record suggests successful funding from various research sources. She has likely mentored numerous graduate and undergraduate students through Chapman University's research programs, contributing to the development of the next generation of scientists in neuroscience and pharmacology.

• Cardiovascular Pharmacology
• Atrial Fibrillation Mechanisms
• Calcium Handling and Signaling
• +۴ مورد دیگر

Dobrev Dobromir is a Full Professor and Director of the Institute of Pharmacology at the Faculty of Medicine, University Duisburg-Essen (Germany). He also holds adjunct professorships at Baylor College of Medicine (USA) and the Montreal Heart Institute (Canada). His research focuses on molecular mechanisms of atrial fibrillation, calcium handling, cardiac inflammation, and drug discovery for arrhythmias. He has authored over 400 peer-reviewed articles and serves as Editor-in-Chief of International Journal of Cardiology: Heart and Vasculature . Education and career highlights include roles as Chair of Experimental Cardiology at Heidelberg University (2010-2012), Postdoctoral Fellow at Dresden University of Technology (1994-1999), and leadership in the Transatlantic Networks of Excellence in Cardiovascular Research (2007-2013). He has received prestigious awards including an Honorary Doctorate from Carol Davila University (2022), Fellowships from the Heart Rhythm Society (FHRS, 2022), and multiple teaching awards (2021). His research bridges basic science and clinical applications, emphasizing inflammatory pathways in atrial remodeling and identifying novel therapeutic targets. He actively contributes to professional organizations including the European Society of Cardiology (ESC), serving as Chair-Elect of its Cardiovascular Pharmacotherapy Working Group. Dr. Dobrev’s work has been published in high-impact journals like Nature Reviews Cardiology , Circulation , and The Lancet , reflecting his global influence in cardiovascular research.

Weihong Linمشاهده پروفایل

استاد

• Neurobiology
• Chemical Sensory Systems
• Olfactory Physiology
• +۳ مورد دیگر

Weihong Lin is a Professor in the Department of Biological Sciences at the University of Maryland, Baltimore County (UMBC). His research focuses on the neurobiological mechanisms underlying chemical sensory systems, particularly olfactory functions and their modulation in response to environmental challenges such as electronic cigarette exposure. He holds a Ph.D. from Colorado State University and has conducted postdoctoral research at the University of Colorado Health Sciences Center and Colorado State University. Education : Ph.D., Colorado State University, 1999 Postdoc, University of Colorado Health Sciences Center, 2003 Postdoc, Colorado State University, 2000 M.S., Zhongshan University, 1988 B.S., Zhongshan University, 1982 Research Interests : Dr. Lin's lab investigates sensory detection mechanisms in the nose, including odor-evoked responses, modulatory networks maintaining olfactory function, and the impact of chemical exposures (e.g., electronic cigarette constituents) on sensory systems. Techniques include transgenic mouse models, electrophysiology, calcium imaging, and behavioral assays. Recent Work Trends : Recent studies emphasize e-cigarette-induced olfactory dysfunction, TRPM5-expressing microvillous cell roles in epithelial homeostasis, and neurotrophin regulation under chemical stress. Research bridges molecular mechanisms with behavioral outcomes in mice. Teaching : Courses include Neurobiology (BIOL 451/651), Cell Biology (BIOL 303), and specialized topics like Chemical Communication and Brain Disorders (BIOL 490/690). Labs/Teams : Directs the Weihong Lin Lab, focusing on olfactory neurobiology and environmental health impacts. Collaborates with institutions like Colorado State University and the University of Colorado on sensory systems research.

Nashaat Gergesمشاهده پروفایل

استاد

• Neuroscience
• Pharmacology
• Synaptic Plasticity
• +۴ مورد دیگر

Nashaat Gerges, PhD, BPharm is a Professor and Chair of the Department of Biopharmaceutical Sciences at the Medical College of Wisconsin (MCW). He holds a secondary appointment as an Associate Professor in the Department of Cell Biology, Neurobiology and Anatomy at MCW. Previously, he served as Associate Director of the Neuroscience Research Center (2010–present). His research focuses on cellular/molecular mechanisms of learning and memory, synaptic plasticity, and neurodegenerative diseases like Alzheimer’s. He has secured over 10 grants (9 as PI) from NIH, Alzheimer’s Association, and others. His work has been published in Nature Communications , Nature Neuroscience , and Journal of Neuroscience , among others. Education: PhD in Pharmacology (University of Houston, 2002), BPharm (University of Assiut, 1995), with postdoctoral training at University of Michigan and University of Houston. Research employs electrophysiology, biochemistry, and microscopy to study synaptic proteins in hippocampal slices. Key interests include neurogranin’s role in calmodulin dynamics, PTEN’s synaptic function in Alzheimer’s models, and polyglutamine aggregation resistance in Dictyostelium. Awards include Alzheimer’s Association Investigator of the Year (2012) and Rho Chi Honor Society membership. He has trained over 10 years in teaching medical/graduate students, emphasizing self-directed learning and innovative pedagogy. Labs/Teams: Leads a lab focused on synaptic plasticity mechanisms using advanced imaging and electrophysiological techniques. Collaborates with multidisciplinary teams on neurodegenerative disease research.

Rachel C Mylesمشاهده پروفایل

استاد

• Ventricular Arrhythmias
• Cardiac Electrophysiology
• Inherited Cardiac Conditions
• +۴ مورد دیگر

Professor Rachel C Myles is the Chair of Cardiac Electrophysiology at the University of Glasgow’s School of Cardiovascular and Metabolic Health, and an Honorary Consultant Cardiologist in the West of Scotland Inherited Cardiac Conditions Service. She holds a first-class degree in Physiological Sciences from the University of Oxford and trained in medicine at Guy’s and St. Thomas’ before completing a PhD in experimental electrophysiology under Prof Godfrey Smith. Her research combines clinical expertise in inherited arrhythmias with experimental work investigating arrhythmia mechanisms in heart failure and cardiomyopathy. Key areas include ventricular arrhythmia initiation, calcium handling defects, and therapeutic target identification. She has held a Wellcome Trust Intermediate Fellowship to establish her independent lab and currently leads projects on cardiac tissue engineering, cardiotoxicity screening in cardio-oncology, and electrophysiological biomarkers for sudden death risk stratification. Education: MB ChB from Guy’s/King’s/St Thomas’ Medical School; DPhil in Cardiovascular Physiology from University of Glasgow. Research focuses on cellular mechanisms underlying ventricular arrhythmias, particularly the role of repolarization alternans and ryanodine receptor dysfunction. Her group uses optical mapping, stem cell-derived models, and computational approaches to bridge cellular findings with clinical arrhythmia outcomes. Notable contributions include defining adrenergic receptor subtype roles in arrhythmia promotion and developing methods to assess myocardial infarction models in small animals. Recent work highlights include engineering heart tissues for cardiac repair, identifying IL-6 as a prognostic marker in heart failure, and investigating hypothermia’s dual effects on arrhythmia risk. Over 35 peer-reviewed papers published in journals like Circulation Research and Cardiovascular Research, with grants from BHF, Wellcome Trust, and Academy of Medical Sciences. Supervised students Eleanor Dickson-Murray (palmitoylation studies) and Kyle Shead (cardio-oncology toxicity screening). Grants/Awards: Wellcome Trust Intermediate Fellowship (2015-2020), multiple BHF Project Grants (2010-2025), Academy of Medical Sciences Starter Grant (2013-2015).

Toby Allenمشاهده پروفایل

استاد

• Computational Biophysics
• Ion Channels
• Membrane Transport Phenomena
• +۴ مورد دیگر

Professor Toby Allen is a computational biophysicist at RMIT University (School of Science, City Campus Australia). His work focuses on membrane transport phenomena, ion channel mechanisms, and computational modeling of biological systems. He holds an ORCID 0000-0002-3521-7950 and is open to supervising Masters/PhD students. PhD, Australian National University (1998) Revson Fellow & Keck Fellow, Cornell University (2001-2004) Assistant Professor, UC Davis (2004-2009) Vice Chancellor’s Senior Research Fellow, RMIT University (2011-present) Research spans Biophysics , Computational Modeling , and Membrane Protein Dynamics . Key areas include: Ion channel selectivity mechanisms Membrane transport of charged molecules Computational pharmacology of ion channels Structural dynamics of ATPases Role of membrane electrostatics in transport Scientific contributions recognized through: Revson Fellowship , Cornell University Keck Fellowship , Cornell University NSF Career Award , UC Davis Chancellor’s Fellow , UC Davis His group receives funding from the Australian Research Council , NHMRC , NIH , and supercomputing agencies. Teaching responsibilities include Statistical Physics and Electromagnetism courses.

Ari Berkowitzمشاهده پروفایل

استاد

• Behavioral Neurobiology
• Spinal Cord Physiology
• Motor Control
• +۳ مورد دیگر

Ari Berkowitz is a Presidential Professor and Director of Graduate Studies for biology programs at the University of Oklahoma's School of Biological Sciences. He also directs the Cellular & Behavioral Neurobiology Graduate Program. His research focuses on how the nervous system selects and generates appropriate behaviors, using the turtle spinal cord as a model to study rhythmic limb movements like scratching and swimming. Education: Ph.D., Neurosciences, Washington University (1993) A.B., Chemistry, University of Chicago (1984) Research Interests: Berkowitz investigates spinal cord networks controlling limb movements in turtles, focusing on how multifunctional and specialized neurons coordinate behaviors. His work reveals shared and distinct neural circuits for swimming, scratching, and flexion reflexes. Awards & Grants: President's Associates Presidential Professorship (2015-present) Multiple NSF and Oklahoma Center awards for spinal interneuron research Capranica Foundation Award in Neuroethology (1995) Teaching: Teaches courses like Behavioral Neurobiology, Human Physiology, and Diversity of Biological Sex Characteristics. Engages in outreach through neuroscience demonstrations at museums. Labs/Teams: Leads the Berkowitz Lab, focusing on spinal cord neural circuitry and motor behavior control.

• Cell Biology
• Physiology
• Ubiquitylation
• +۹ مورد دیگر

Daniela Rotin is a Professor at the University of Toronto, affiliated with the Temerty Faculty of Medicine, and holds appointments in the Department of Biochemistry and the Department of Physiology. She is a senior scientist in the Cell Biology Program at The Hospital for Sick Children (SickKids) in Toronto, where her research focuses on ubiquitin ligases, particularly the Nedd4 family, and their roles in cellular regulation, epithelial physiology, and disease. Her research interests include cell biology, physiology, ubiquitylation, endocytosis, cystic fibrosis, autophagy, epithelial biology, ion channel regulation, and protein trafficking. She has made significant contributions to understanding the regulation of the epithelial sodium channel (ENaC) by ubiquitin ligases such as Nedd4-2, and the discovery of primate-specific splice isoforms like Nedd4-1(NE), which regulates autophagy in response to nutrient availability. Her recent publications highlight a strong trend in molecular mechanisms of ubiquitin ligase activity, stress signaling (e.g., p38-MAPK, WNK kinases), and cellular responses to osmolarity and ion imbalances. Her work integrates cell biology, biochemistry, and physiology to uncover novel regulatory pathways in health and disease, with implications for cystic fibrosis, hypertension, epilepsy, and cancer. Dr. Rotin has not been noted to have received specific scientific awards in the provided text, but her high citation metrics (h-index 33, i10-index 48, over 4,700 citations) reflect significant scholarly impact. She collaborates extensively with researchers at SickKids, the University of Toronto, and international institutions. She advises a research team studying ubiquitin-mediated proteostasis, and her lab has secured funding for projects on ENaC regulation, autophagy, and organoid models of epithelial disease. She leads a research group that utilizes advanced techniques including CRISPR-Cas9, proteomics, and iPSC-derived organoids. Dr. Rotin is actively involved in research through her laboratory at SickKids, where she investigates the molecular basis of protein trafficking, cellular stress responses, and the pathophysiology of epithelial disorders. Her team includes postdoctoral fellows, graduate students, and research associates working on ubiquitin ligases and their roles in development and disease.