Andrew DeVilbiss

Andrew DeVilbiss, Ph.D., serves as an Instructor (academic rank equivalent to Lecturer) in the Department of Internal Medicine at UT Southwestern Medical Center, where he is a member of the Division of Hematology and Oncology. He joined the faculty in 2024 following a postdoctoral fellowship at UT Southwestern's Children's Research Institute.

Education:

• Dual bachelor's degrees in Biochemistry and Cellular and Molecular Biology from the University of Wisconsin
• Ph.D. in Philosophy from the University of Wisconsin
• Postdoctoral fellowship at UT Southwestern Medical Center's Children's Research Institute

Dr. DeVilbiss' research program centers on the molecular and metabolic regulation of hematopoiesis, with particular emphasis on hematopoietic stem cell biology, erythroid maturation, and leukemogenesis. His work integrates transcriptional regulation, epigenetics, and metabolism to dissect how genetic networks control blood cell development and disease. Key investigations include the role of GATA factors, chromatin modifiers, and metabolic pathways such as ascorbate metabolism and redox regulation in stem cell function and blood disorders.

Analysis of his publication record (2013-2025) reveals an evolving research trajectory from foundational studies on transcriptional mechanisms in hematopoiesis toward contemporary investigations of metabolic regulation in stem cells. Recent work (2021-2025) demonstrates significant focus on ascorbate deficiency, redox sensors (KEAP1), and autophagy in stem cell quiescence, self-renewal, and aging, with implications for neutropenia, T cell dysfunction, and acute myeloid leukemia. His publications span high-impact journals including Blood, Science Immunology, and Cell Stem Cell.

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