جست‌وجوی استاد و پژوهشگر

Huiqing Zhouمشاهده پروفایل

استادیار

• Epitranscriptomics
• RNA Modifications
• Nucleic Acid Chemistry
• +۴ مورد دیگر

Huiqing (Jane) Zhou is an Assistant Professor of Chemistry at Boston College, affiliated with the Morrissey College of Arts and Sciences and the Chemistry Department. Her research focuses on developing technologies to map and modulate RNA chemical modifications (epitranscriptome) in mammalian systems. She employs interdisciplinary approaches including directed evolution, biochemistry, mass spectrometry, and structural biology to study the regulatory mechanisms of these modifications in gene expression and disease. Education: B.S., Nankai University Ph.D., Duke University Research Interests: Her lab explores how RNA modifications influence transcript stability, interactions, and expression, with applications in disease modeling and gene therapy. Key areas include base-resolution mapping of modifications, engineering tools for modification manipulation, and understanding dysregulated epitranscriptomes in diseases like Alzheimer’s. Publications: Her work spans publications in Nature Methods , Biochemistry , and Nucleic Acids Research , focusing on reverse transcriptase evolution, Hoogsteen base pairing dynamics, and RNA modification detection technologies. Awards: 2017 Chicago Fellows Fellowship. Lab & Funding: Supported by Boston College and grants from the National Institutes of Health (NIGMS, NCI). Her lab develops cutting-edge tools to visualize and modulate RNA modifications, aiming to identify novel drug targets and advance gene therapy strategies.

Elaine Frawleyمشاهده پروفایل

دانشیار

• Bacterial Pathogenesis
• Metal Homeostasis
• Antimicrobial Resistance
• +۳ مورد دیگر

Dr. Elaine Frawley is an Associate Professor of Biology at Rhodes College, where she leads the Frawley Lab focusing on bacterial survival mechanisms during host infection. Her research emphasizes how pathogens like Salmonella Typhimurium adapt to nitrosative stress and metal ion imbalances, particularly manganese and zinc homeostasis. She collaborates with the Peterson and Bea labs on novel antimicrobial compound development. Education: PhD in Biology and Biomedical Sciences from Washington University (2010), BA in Biology from Washington University (2003). Research interests include bacterial metal transport systems, nitric oxide defense strategies, and antimicrobial resistance mechanisms. Current projects investigate manganese's role in stress resistance and screen wasp venom-derived peptides for antimicrobial activity. Publications highlight work on MntP/YiiP efflux pumps, EMP peptide toxicity, and NsrR regulon stress responses. Her lab actively involves undergraduate researchers in both basic science and applied drug discovery projects. Grants and funding support collaborative drug discovery efforts targeting efflux pump mechanisms. She maintains interdisciplinary connections through Rhodes College's Biochemistry and Environmental Studies programs.

Abhinandan Chowdhuryمشاهده پروفایل

پژوهشگر

• Toxicology
• Venom Research
• Bioanalytical Techniques
• +۲ مورد دیگر

Abhinandan Chowdhury is a Researcher at The University of Queensland's School of Biological Sciences, specializing in venom toxicology and therapeutic development. His work focuses on small molecule enzyme inhibitors to neutralize snake venom effects, supported by industry collaborations like Ophirex. He employs advanced bioanalytical techniques including Electric Cell-substrate Impedance Sensing (ECIS), StarMax Coagulation Analyzer, and Thromboelastography (TEG 5000) under Good Laboratory Practices (GLP) standards. Education: PhD in Biological Sciences, The University of Queensland (2023) Research Focus: Dr. Chowdhury investigates venom-induced coagulopathies and neurotoxic mechanisms across global snake species, with emphasis on enzyme inhibitor therapeutics (e.g., varespladib). His research bridges academic discovery and clinical translation, utilizing cellular models and human plasma assays to develop complementary treatments for antivenom limitations. Publication Trends: Analysis of his 15 most recent publications (2021-2025) reveals consistent focus on venom coagulotoxicity and inhibitor efficacy across viperid/elapid species. Key themes include ontogenetic venom variation, taxon-selective pathophysiology, and cross-species antivenom neutralization challenges, predominantly targeting African, Australian, and Palearctic snakes. Research Leadership: He manages complex laboratory operations, mentors students, and directs instrumentation for high-throughput venom analysis. His industry partnerships demonstrate commitment to translating biochemical findings into real-world snakebite solutions, particularly through small molecule therapeutic development.

• Virology
• Ebola Virus Research
• Lassa Fever Virus
• +۳ مورد دیگر

James Morgan Cunningham is an Associate Professor of Medicine (Microbiology and Molecular Genetics) at Brigham and Women's Hospital, affiliated with Harvard Medical School. His research focuses on viral entry mechanisms, particularly for Ebola and Lassa viruses, with a focus on developing antiviral therapies and understanding host-pathogen interactions. He has held part-time academic roles since at least 2024, as noted in his most recent publications. Research Interests: Dr. Cunningham's work spans viral pathogenesis, antiviral drug discovery, and the structural biology of viral glycoproteins. He has made significant contributions to understanding how cholesterol metabolism and cellular receptors (like LAMP1) influence viral entry. His research also explores the biochemical basis of Ebola glycoprotein activity during outbreaks and the development of small molecule inhibitors targeting enveloped viruses. Grants & Collaborations: He has secured NIH funding for projects like the New England Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (2003-2015) and studies on small molecule inhibitors for viral entry (2014-2019). Notable collaborations include work with Sean Whelan on Ebola virus entry and Dennis Kasper on biodefense strategies. Publications: His work spans over three decades, with key contributions to understanding Ebola virus glycoprotein proteolysis (Science, 2005), Lassa fever virus cholesterol dependency (2018), and co-authorships with leaders in virology like Kartik Chandran and Kartik Chandran. Recent studies (2024) explore NAD metabolome changes in severe COVID-19 cases.

• Electrocatalysis
• Sustainable Chemistry
• Material Design
• +۳ مورد دیگر

Prof. Nikolay Kornienko leads a research group at the University of Bonn's Institute of Inorganic Chemistry focused on sustainable energy conversion. His work develops catalytic materials for converting renewable electricity and abundant molecules into valuable chemicals. Research pillars: 1) Designing electrocatalysts from molecular to heterogeneous systems for small molecule activation; 2) Innovating electrochemical routes for chemical/fuel production; 3) Developing operando spectroscopy to visualize catalytic processes in real-time. Key research areas include CO2 utilization for chemical synthesis, nitrogen fixation, and developing novel battery technologies. Publications demonstrate focus on sustainable pathways for chemical manufacturing and energy conversion.

Rachel Martinمشاهده پروفایل

استاد

• Analytical Chemical Biology
• Physical Chemistry
• Chemical Physics
• +۳ مورد دیگر

Rachel Martin is a Professor in the Department of Chemistry at the University of California, Irvine (UCI). Her research focuses on analytical chemical biology , physical chemistry , and chemical physics , with a particular emphasis on protein structure, stability, and dynamics. She investigates molecular chaperones, lens crystallins, and extremophilic enzymes, often employing NMR spectroscopy and computational modeling. Dr. Martin's work integrates biophysical chemistry with instrumentation development, such as NMR probe fabrication and automated testing systems. She also explores educational innovations, including specifications grading in chemical biology courses. Her research has implications for understanding protein aggregation in aging, cold adaptation mechanisms, and enzyme function in extreme environments. Recent projects include studying deamidation effects on γ-crystallins, radiation resistance in lens proteins, and collaborative efforts in protein crystallization and structure determination. Her lab leverages open-source tools and maker methodologies for experimental instrumentation.

Kabirul Islamمشاهده پروفایل

دانشیار

• Epigenetics
• Organic Synthesis
• Bioorganic Chemistry
• +۶ مورد دیگر

Kabirul Islam is an Associate Professor in the Department of Chemistry at the University of Pittsburgh, affiliated with the Dietrich School of Arts and Sciences. His research focuses on chemical approaches to understand epigenetic mechanisms in human biology and disease, integrating organic synthesis, bioorganic chemistry, and structural biology. Key projects include developing chemoproteomic tools like interaction-based protein profiling (IBPP) and allele-specific chemical genetics to study epigenetic regulators. Research interests span epigenetic protein interactions, metabolic-epigenetic links (e.g., 2-ketoglutarate-dependent demethylases), and precision medicine targeting epigenetic drivers of cancer and obesity. The Islam Lab employs synthetic chemistry, protein engineering, and advanced spectroscopic methods to modulate and interrogate chromatin modifications. Publications highlight contributions to TET enzyme analysis, histone demethylase inhibition, and photochemical tools for interactome profiling. Ongoing work explores allele-specific modulation of epigenetic machinery and boron-based oligonucleotide delivery systems. Lab activities include mentoring graduate and undergraduate students, postdoctoral researchers, and collaborations across chemistry, biology, and materials science. The group actively seeks to bridge chemical innovation with biomedical applications, emphasizing translational research in epigenetic therapies.

• Synthetic Chemistry
• Fluorescent Sensors
• Molecular Self-Assembly
• +۳ مورد دیگر

Dr. Senjuti Halder is a Research Fellow in the School of Chemistry at the University of St Andrews. Her research focuses on synthetic chemistry, molecular self-assembly, and the development of fluorescent sensors for anions, biomolecules, and environmental contaminants. She specializes in designing functional materials such as aggregation-induced emission (AIE) luminogens and bis-urea-based receptors, with applications in biomedical and environmental detection systems. Her work includes studies on the aggregation behavior of small molecules, solvent-tunable properties, and interactions with biological systems like human serum albumin. She has explored biomineralization processes directed by whey proteins and developed novel sensors for hypochlorite, hydrazine, and sulfite using cyanine and Schiff base chemistries. Dr. Halder’s research also involves crystallographic analysis of water clusters and halide encapsulation within molecular frameworks. Her publications span from 2018 to 2024, emphasizing interdisciplinary approaches at the interface of chemistry, materials science, and analytical techniques. She contributes to advancing sensing technologies and understanding fundamental molecular interactions in aqueous and physiological conditions.

• Malaria Research
• Parasitology
• Drug Development
• +۳ مورد دیگر

Dr. Danny Wilson is an Externally-Funded Research Fellow (C) at the University of Adelaide, affiliated with the School of Biological Sciences within the Faculty of Sciences, Engineering and Technology. His research focuses on understanding the unique biology of single-cell parasites like malaria (Plasmodium spp.) and Toxoplasma gondii, aiming to develop novel vaccines and drug treatments. He has secured significant grants and fellowships, including the NHMRC Peter Doherty Early Career Fellowship and multiple DAAD/Universities Australia-Germany collaborations. His work employs advanced techniques such as gene editing, fluorescence microscopy, and proteomic analysis to study parasite invasion mechanisms and identify therapeutic targets. The lab also investigates the efficacy of azithromycin analogues and other small molecules against malaria and Toxoplasma, with a focus on overcoming drug resistance. Dr. Wilson has been awarded several prestigious fellowships, including the Hospital Research Foundation Mid-career Fellowship and the University of Adelaide Beacon Fellowship. These accolades reflect his contributions to malaria research and drug development. In terms of grants and funding, he has served as Chief Investigator (CIA), Lead-CI, or Co-CI on projects from NHMRC, ARC, DAAD/Universities Australia-Germany, and the South Australian Sheep Industry Fund. His research has also been supported through collaborations with international institutions and industry partners. Dr. Wilson is actively involved in teaching, including lectures on Infection and Immunity A, Biomedical Science, and mentoring undergraduate students. He is eligible to supervise Masters and PhD students, fostering the next generation of researchers in malaria and parasitology. His laboratory is equipped with advanced microscopy systems, such as the Oxford Nano-imager NIM 4 and Imaris software, enabling cutting-edge analysis of parasite biology. These tools are critical for his work in mapping subcellular structures and identifying drug targets.

• Pharmacology
• Drug Discovery
• Cancer Research
• +۳ مورد دیگر

Gregory Thatcher is a Professor in the Department of Pharmacology and Toxicology at the University of Arizona's College of Pharmacy, affiliated with the Skaggs Pharmaceutical Sciences Center. He holds a PhD from the University of Toronto (1986) and a BSc from the University of Manchester (1981), with postdoctoral experience at the University of Sheffield and Oxford University. His research focuses on small molecule therapeutics, drug discovery, and translational medicine. Dr. Thatcher founded a campus-wide drug discovery center at the University of Illinois at Chicago (UIC) in 2013, advancing academic drug discovery in the Chicagoland region. He launched a biotech startup in 1997, advancing an Alzheimer’s drug to clinical trials. His NIH-funded research (since 2003 via NCI, NIA, NHLBI, NIAID) has produced over 170 publications and numerous patents. Two compounds, Rintodestrant and TTC-352, reached Phase 1 clinical trials for metastatic breast cancer in 2019. He maintains a lab actively involved in developing novel therapeutic strategies, with a focus on oncology and neurodegenerative diseases. His work bridges academia and industry, emphasizing translational research and clinical impact.

Harald Adeمشاهده پروفایل

استاد

• Organic Electronics
• Materials Science
• Photovoltaics
• +۳ مورد دیگر

Harald Ade is the Goodnight Innovation Distinguished Professor of Physics at North Carolina State University (NCSU) , leading the Organic and Carbon Electronics Laboratory . He has been a faculty member since 1992 and became Full Professor in 2001, with notable roles including Director of the Graduate Program in Physics (2006–2013). His expertise lies in developing advanced characterization techniques like NEXAFS microscopy and X-ray scattering to study organic electronic materials, particularly for solar cell applications. Education: Graduate of Stony Brook University. Awards include NSF Young Investigator Award, APS Fellow, and Clarivate Analytics Highly Cited Researcher (2017–2018). His research focuses on polymer morphology, photovoltaic device stability, and sustainable materials for energy applications. External engagements include advisory roles at the Advanced Light Source and BESSY-II Synchrotron. Research interests span organic electronics, nanomaterials, and X-ray-based analytical methods. Over 150+ publications highlight contributions to high-efficiency solar cells and novel instrumentation. His work bridges materials science and energy technology, emphasizing practical applications of fundamental discoveries. Key Techniques: NEXAFS microscopy, R-SoXS, X-ray dichroism Focus Areas: Organic photovoltaics, polymer morphology, materials characterization Grants: ~$14.5M in total research funding Current projects explore eco-friendly solvents, device stability, and novel light-harvesting materials. His lab collaborates globally on synchrotron-based studies and industry partnerships.

Francesco Gentileمشاهده پروفایل

استادیار

• Computer-Aided Drug Discovery
• Deep Learning in Drug Discovery
• Structure-Based Virtual Screening
• +۳ مورد دیگر

Francesco Gentile is an Assistant Professor in the Department of Chemistry and Biomolecular Sciences at the University of Ottawa, Faculty of Science. His research focuses on computational strategies for drug discovery, leveraging AI and deep learning to accelerate virtual screening and target unconventional drug targets such as protein-protein interactions. He leads the Gentile Lab, which investigates cancer drug resistance and develops tools like DockBox and Deep Docking for structure-based drug discovery. Education: PhD in Computational Physics from the University of Alberta (2014-2019), postdoctoral training at the Vancouver Prostate Centre under Art Cherkasov. Awards include Alberta Innovates Scholarship and CIHR Fellowship. Research interests span AI-driven drug discovery, chemical space exploration, and synergistic therapies for cancer. The lab collaborates with the Ottawa Institute of Systems Biology and AI4Science@uOttawa. Key publications include work on SARS-CoV-2 protease inhibitors, LRRK2 domain targeting, and AI in early-stage drug discovery. Over 20 students and postdocs have been advised, with active projects in PROTAC design and computational modeling. Lab members include postdocs, graduate students, and undergraduates from diverse backgrounds. Current tools developed include Pose Ensemble GNNs and PROTACable pipelines.

Alberto Celmaمشاهده پروفایل

پژوهشگر

• Environmental Chemistry
• Analytical Chemistry
• Environmental Toxicology
• +۳ مورد دیگر

Alberto Celma is a Researcher at the Division of Environmental Organic Chemistry and Ecotoxicology, Swedish University of Agricultural Sciences (SLU). His work focuses on developing analytical tools for monitoring organic micropollutants in aquatic environments using high-resolution mass spectrometry (HRMS) and ion mobility separation. Key research areas include stormwater pollution, toxicity assessment, and effect-directed analysis. Celma leads projects such as NecroPOPs (human burial site impacts) and SAFESTORM (stormwater toxicity), emphasizing sustainable water management and circular economy applications. Research interests span environmental chemistry, analytical method development, and public health applications of wastewater-based epidemiology. His contributions include advancing non-target screening protocols, optimizing HRMS workflows, and studying new psychoactive substances (NPS) in wastewater. Celma collaborates internationally through initiatives like NORMAN and ESAR-Net, promoting standardized approaches in environmental analysis. Key Projects: NecroPOPs, PMT-hotspots, SAFESTORM, Residues to Best Use (Biochar) Labs: POPs Lab (specializing in persistent organic pollutants) Grants/Advising: Primary Investigator (PI) on multiple EU-funded projects; no formal advisee list provided.

• Asteroid mineralogy
• Planetary science
• Space weathering
• +۵ مورد دیگر

Thais Mothe-Diniz is a Researcher and Adviser at the Faculty of Natural Sciences, NTNU, holding roles such as Research Adviser in the NV Faculty Administration and Admin Coordinator for the FME-Hydrogeni Project. She specializes in asteroid mineralogy and surface composition, with expertise in EU project management. Her research focuses on asteroid family dynamics, spectroscopic analysis, and planetary science. PhD in Astronomy (2002, mineralogy of small planets) MSc in Astrophysics (1998, Celestial Mechanics) Bachelor in Pure Mathematics (1994, Maxwell's equations) Research interests include asteroid mineralogy, space weathering processes, and the structural analysis of asteroid families. She has extensive experience in coordinating international projects like REVITALISE and SisAl Pilot, and manages NTNU's collaborations with institutions like Jotun and the Paris Observatory. Publications span asteroid taxonomy, volatile detection (e.g., ice on 24 Themis), and compositional studies of basaltic asteroids in the outer main belt. Her work bridges observational astronomy and planetary formation theories, with contributions to missions like NASA's Dawn targeting Ceres and Vesta. Notable competencies include certified conflict mediation (Red Cross), project leadership, and technical skills in Linux/macOS systems.

Thet Thet Htarمشاهده پروفایل

مدرس ارشد

• Medicinal Chemistry
• Organic Synthesis
• Natural Products
• +۵ مورد دیگر

Dr. Thet Thet Htar is a Senior Lecturer at the Malaysia School of Pharmacy, Monash University, specializing in medicinal chemistry and molecular imaging. She holds a PhD from Cardiff University and has been actively involved in academic research since 2004. Her work focuses on small molecule synthesis, molecular docking, and drug design targeting breast cancer and antiviral agents. Education: BPharm (Honours) from Cardiff University (1999), PhD in Medicinal Chemistry from Cardiff University (2004). Research interests include estrogen receptor-targeted fluorescent probes, GPER-1 ligand interactions, and natural product-based drug discovery. She has led projects such as the development of breast cancer imaging probes and studies on curcumin’s therapeutic potential. Key scientific contributions span over 40 publications, including work on anti-leishmanial agents, SARS-CoV-2 inhibitors, and phytochemical screening. She actively collaborates on interdisciplinary projects, including clinical trials for wound care and drug delivery systems. Teaching commitments include medicinal chemistry and pharmaceutical sciences at the undergraduate level. She has supervised seven PhD students and one Master’s student since 2017, contributing to both academic and clinical research advancements.