جستجوی استاد راهنمای دانشگاهی

Jeff Gehlhausen, MD, PhD, is an Assistant Professor in Dermatology at Yale School of Medicine , specializing in complex autoimmune skin conditions like cutaneous lupus, dermatomyositis, and vasculitis. His research integrates immune system biology with clinical practice, focusing on autoimmune inflammatory skin diseases using patient-derived samples and mouse models. Education: MD and PhD from Indiana University, postdoctoral fellowship with Akiko Iwasaki (Yale), internship at Vanderbilt, residency at Yale. Research Themes: Type I interferons in pathology, endogenous retroelements in autoimmunity, and clinical trials like the LISTEN Study for Long COVID. Scientific Awards: 2024 Top Doctors List (Yale Medicine) 2025 Women’s Health Research at Yale Pilot Project Program Award Collaborations: Sarika Ramachandran, Akiko Iwasaki, Christine Ko, Fotios Koumpouras, Alicia Little, Jennifer McNiff. Leadership: Principal Investigator of the Gehlhausen Lab, with affiliations to the Autoimmune Skin Disease Program and Psoriasis Treatment Program at Yale Medicine.

• Autoimmune Diseases
• Dermatology
• Connective Tissue Diseases
• +۷ مورد دیگر

Alicia Little, MD, PhD, is an Assistant Professor of Dermatology at Yale School of Medicine (Yale University) and Director of the Yale Vulvar Dermatology Clinic. She leads interdisciplinary management of vulvar dermatological conditions and maintains clinical expertise in autoimmune/inflammatory skin diseases including cutaneous lupus, dermatomyositis, lichen sclerosus, psoriasis, and atopic dermatitis. Her education includes: Undergraduate: Amherst College (Chemistry & Neuroscience) Medical School: Yale University School of Medicine Research Fellowship: Immunobiology, Yale University Internship: Yale-New Haven Hospital (Internal Medicine) Dr. Little's research focuses on immunopathological mechanisms in autoimmune skin diseases, particularly T-cell mediated processes in cutaneous lupus. She investigates hypoxia-inducible factors in disease pathogenesis and develops targeted therapies. Recent work explores comorbidities in lichen sclerosus and dermatological manifestations of COVID-19 infections/vaccines. Her publications demonstrate consistent focus on: autoimmune dermatoses (especially lupus and lichen sclerosus), therapeutic innovation, epidemiological patterns, and COVID-19 skin manifestations. Article keywords frequently involve immunodermatology, pathogenesis, and clinical-translational research. Dr. Little directs the Vulvar Dermatology Clinic and collaborates with the Craft Lab and Autoimmune Skin Disease Program. She serves on the Janeway Society and has received research grants from the Colton Center for Autoimmunity.

• Autoimmune Skin Diseases
• Women's Skin Health
• Inflammatory Dermatology
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Goran Micevic is an Assistant Professor at Yale School of Medicine and Yale Cancer Center , leading a research group focused on melanoma immunobiology and inflammatory skin diseases. His work bridges epigenetic mechanisms with immune response regulation in cutaneous malignancies. Board-certified in Dermatology and Dermatopathology (2024) Affiliated with Molecular Medicine, Pharmacology, and Physiology Program Member of Janeway Society and Hamburg House Affiliates Research interests include: Epigenetic regulation in melanoma formation Immune checkpoint modulators (PD-1/PD-L1) Epigenetics-Immunology crosstalk Prognostic methylation signatures T-cell exhaustion in melanoma Therapeutic targeting of DNMT3B Clinical interests span cutaneous malignancies, atopic dermatitis, alopecia areata, and psoriasis. His lab employs mouse models, single-cell sequencing, and CRISPR technology to explore next-generation cancer immunotherapies. Scientific awards include: Dermatology Foundation Career Development Award (2023) Ruth L. Kirschstein Fellowship (2019) Yale's Selma & Karl Folkers Prize (2018) Milton Winternitz Prize (2018) Students include co-mentored graduate researcher Maya Deshmukh . Recent grants include support from the Skin Cancer Foundation (2023) for epigenetic immunotherapy research.

• Melanoma Epigenetics
• Skin Immunobiology
• Cancer Immunotherapy
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Erin Molloy is an Assistant Professor in the Department of Computer Science at the University of Maryland, College Park. She holds appointments in UMIACS (University of Maryland Institute for Advanced Computer Studies) and the Center for Bioinformatics and Computational Biology (CBCB). Her research focuses on developing efficient algorithms for phylogenetic tree reconstruction, leveraging distributed-memory systems and genomic data analysis. She earned her Ph.D. in Computer Science from the University of Illinois at Urbana-Champaign in 2020 and completed a postdoctoral fellowship at UCLA's Machine Learning and Genomics Lab. Research interests include computational methods for evolutionary biology, scalable phylogenetics, high-performance computing for genomics, and applications in metagenomics, cancer genomics, and microbial ecology. Her lab, the Molloy Lab, emphasizes interdisciplinary approaches combining algorithm design, statistical guarantees, and parallel computing. Key collaborations include work with Mihai Pop (UMIACS Director) on metagenomic taxon identification, Brantley Hall on microbiome gene functions, and Michael Cummings on phylogeny estimation methodologies. She is funded by the NSF CAREER Award, USDA grants, and the NCI-UMD Partnership Program. Advising includes PhD students in CS, AMSC, and BISI programs. Current projects explore cell lineage tree reconstruction, species tree estimation under low-homoplasy models, and algorithmic improvements for large genomic datasets. The lab actively participates in conferences like ISMB/ECCB and workshops on phylogenomics.

• Bioinformatics and Computational Biology
• Phylogenetics
• Algorithms for Genomics
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Jonathan Perreault is an Associate Professor and holder of the Chair in Nanobiophotonics at the Armand-Frappier Health Biotechnology Center, National Institute of Scientific Research (INRS). His research focuses on understanding RNA's role in gene regulation, particularly in bacteria, including riboswitches, small RNAs, and their applications in biosensors and environmental biotechnology. He holds a B.Sc. and Ph.D. in Biology/Biochemistry from Université de Sherbrooke and completed a postdoctoral fellowship at Yale University. His research interests include microbiology, biochemistry, and RNA biology, with a focus on non-coding RNAs' regulatory roles in bacterial processes such as motility and biofilm formation. His team uses bioinformatics, molecular biology, and biophysics to discover novel RNAs and study their functions in environmental and pathogenic contexts. Publications highlight advancements in RNA structure-function relationships, metagenomic approaches to RNA discovery, and applications in wastewater treatment and viral expression strategies. His work bridges fundamental RNA biology with practical applications in biotechnology and environmental science. Dr. Perreault’s lab collaborates on projects involving RNA-based biosensors and environmental microbiology. His expertise spans from bench science to computational tools for RNA analysis, contributing to both academic and applied research outcomes.

• Microbiology
• Biochemistry
• RNA Biology
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Jelena Erceg is an Assistant Professor in the Department of Molecular and Cell Biology / Genetics and Genomics at the University of Connecticut. She holds a Ph.D. from EMBL/University of Heidelberg and completed a postdoctoral fellowship at Harvard Medical School. Her research focuses on understanding multi-scale genome organization and gene regulation in diploid organisms, particularly exploring how genome architecture influences cell fate and disease. She employs advanced genomic and single-molecule imaging techniques, including super-resolution microscopy, to study chromosomal interactions in development and disease contexts. Her work integrates experimental and computational approaches, as seen in studies on chromosome pairing in Drosophila embryos and the functional implications of 3D genome landscapes. Key contributions include insights into homolog pairing dynamics, centromere structure, and the role of ultraconserved elements in genome organization. Dr. Erceg's lab also develops innovative imaging tools for haplotype visualization and structural genomic analysis. Selected publications highlight her exploration of evolutionary genomic mechanisms, disease-related structural variations, and the interplay between chromosomal architecture and gene regulation. Her research bridges fundamental biology with translational applications in understanding genetic disorders.

• Genome Organization
• Gene Regulation
• 3D Chromosome Architecture
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Steven Zimmerly is a Professor in the Department of Biological Sciences at the University of Calgary, Faculty of Science. His research focuses on group II introns' catalytic RNA properties, retroelement behavior, and evolutionary implications. He holds a B.A. in Chemistry from Goshen College (1986) and a Ph.D. in Biophysics from Yale University (1992). Research interests include the self-splicing mechanisms of group II introns, their mobility strategies, structural diversity, and evolutionary relationships. Notably, his work revealed how some introns insert after transcriptional terminators to avoid disrupting host genes. Zimmerly has contributed to databases tracking mobile group II introns and elucidated their roles in horizontal gene transfer and parasitic genomic dynamics. He has been recognized with the GREAT Supervisor Award (2018), AHFMR Senior Scholar (2003), and AHFMR Scholar (1998). Courses taught include BCEM 413 (Laboratory Techniques II) and CMMB 451 (Molecular Analysis of Biological Systems). Over 15 key publications span RNA structure-function studies, retroelement evolution, and bacterial genomic analyses. Grants & Funding: Not explicitly listed in the text. Labs/Teams: Research group focuses on RNA biology and molecular evolution; collaborates widely (e.g., with Lambowitz, Doulatov, and others).

• RNA Biology
• Molecular Genetics
• Evolutionary Biology
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Claude Perreault is a Full Professor at the Université de Montréal, affiliated with the Faculty of Medicine and the Department of Medicine. He leads research at the Institut de recherche en immunologie et en cancérologie (IRIC). His work focuses on T-cell biology, immunotherapy, and cancer research, particularly targeting tumor-specific antigens and improving immune system function. He has supervised numerous PhD and Master's students and holds several grants from organizations like the Canadian Cancer Society and the Terry Fox Research Institute. Research Interests: Perreault’s research explores T-cell development, immune self-tolerance, and cancer immunotherapy. Key areas include understanding thymus function, MHC class I antigen presentation, and developing vaccines against cancers like leukemia and ovarian cancer. His lab investigates how non-canonical translation and transposable elements influence immune responses and tumor antigen discovery. Grants & Collaborations: He leads projects funded by the Canadian Institutes of Health Research (CIHR), Terry Fox Foundation, and industry partners. Notable collaborations include developing therapeutic vaccines and studying tumor-specific antigens in acute myeloid leukemia (AML) and lymphoblastic leukemia (ALL). Awards: He received the Prix Léo-Pariseau (2011) for contributions to science communication. His work has been highlighted in multiple media outlets, emphasizing breakthroughs in immunotherapy and cancer vaccines. Labs & Teams: Perreault’s lab at IRIC integrates proteogenomics, immunology, and clinical translation. He collaborates with teams like ThéCell (Therapeutic Cell Network) and the Montreal Cancer Consortium (MCC), advancing personalized cancer immunotherapy.

• Immunology
• Cancer Research
• T-cell Biology
• +۷ مورد دیگر

Jennifer Erwin is an Assistant Professor of Neurology and Neuroscience and an Investigator at the Lieber Institute for Brain Development (LIBD) in Baltimore, MD. Her research integrates molecular neuroscience with human stem cell models and computational approaches to understand the role of retroelements and somatic mosaicism in brain development and disease. Her research focuses on developmental neuroscience , cellular and molecular mechanisms in the brain, and the neurobiology of disease . Specifically, she investigates how gene-by-environment interactions contribute to psychiatric and neurodegenerative disorders through the activity of retroelements such as LINE-1 and SVA, which can cause somatic mosaicism in neurons. This work has implications for understanding schizophrenia, aging, and rare disorders like X-linked Dystonia Parkinsonism. The Erwin lab employs a multidisciplinary approach combining human induced pluripotent stem cell (iPSC) models , postmortem human brain tissue analysis , and bioinformatics to uncover novel molecular pathways. The overarching goal is to identify targets for neuroprotective therapies in brain disorders where genetic and environmental factors converge. She is affiliated with the Neuroscience Training Program , indicating her involvement in mentoring graduate students. While no specific awards or publications are listed in the profile, her research program is centered on innovative mechanisms in brain disease, suggesting active grant support and scholarly output. Jennifer Erwin leads a research laboratory at the Lieber Institute for Brain Development, located at 855 N. Wolfe Street, Baltimore, MD, in the Rangos Building. The lab focuses on retrotransposon biology and its impact on neural diversity and disease susceptibility.

• Developmental Neuroscience
• Cellular and Molecular Neuroscience
• Neurobiology of Disease
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Christine J. Ko, MD is Professor of Dermatology and Pathology at Yale School of Medicine. She is board certified in dermatology with a specialty certificate in dermatopathology. Dr. Ko primarily works in the Division of Dermatopathology, where she renders diagnoses for skin biopsies sent from Yale Dermatology Associates and other Connecticut dermatology practices. She specializes in Transplant Dermatology, providing care for organ transplant patients who are on immunosuppressive medications and at higher risk for skin cancer. Professor of Dermatology (Primary Appointment) Professor of Pathology (Secondary Appointment) Member of Cutaneous Granulomatous Disorders Program Participant in Genomics, Genetics, and Epigenetics research Yale Cancer Center member Dr. Ko received her undergraduate degree from Princeton University (1995) and her medical degree from New York University School of Medicine (1999). She completed her internship at UCLA (2000), dermatology residency at University of California, Irvine (2003), and a postdoctoral fellowship at UCLA (2004). Her primary research focus centers on distinguishing diseases that present similarly both clinically and microscopically. Dr. Ko has published extensively in clinical dermatology and dermatopathology, including authoring books such as "Dermatology: Visual Recognition and Case Reviews," "Dermatology Essentials," and "Dermatopathology: Diagnosis by First Impression." She is particularly interested in skin cancer mechanisms, especially squamous cell carcinoma and keratoacanthoma, and has collaborated with researchers in Genetics and Dermatologic Surgery. More recently, she has explored cognitive bias in medical diagnosis, publishing a two-part series on the topic. Analysis of Dr. Ko's recent publications reveals a strong emphasis on dermatopathology, skin cancer pathology (particularly squamous cell carcinoma), transplant dermatology, and diagnostic methodology. Her work demonstrates extensive collaboration with transplant surgeons like Bohdan Pomahac and Martin Kauke-Navarro, as well as dermatopathologists like Jennifer McNiff and Keith Choate. The breadth of her research spans from molecular genetics of skin disorders to clinical decision-making processes in dermatology. Dr. Ko serves as a Sub Investigator for the clinical trial "Molecular Markers of UV Exposure and Cancer Risk in Skin" and is involved with the Women's Health Research at Yale (WHRY) Pilot Project Program. Her approach emphasizes the importance of correlating clinical and microscopic findings for accurate diagnosis, particularly for complex cases. She is affiliated with multiple research programs including the Cutaneous Granulomatous Disorders Program, Skin & Kidney Cancer Program, Surgical Pathology, and Yale Dermatology Associates. Her work in transplant dermatology has contributed significantly to understanding rejection patterns in facial vascularized composite allografts and long-term outcomes in face transplantation.

• Dermatology
• Dermatopathology
• Skin Cancer Research
• +۵ مورد دیگر

Ning Jiang is a Professor at the Genetics & Genome Sciences Program within the College of Natural Science at Michigan State University . His research focuses on transposable elements, genome diversification, and computational biology in plant systems.

• Transposable Elements
• Genome Diversification
• Computational Biology
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Dr. Ben Barron-Millar is a researcher at Newcastle University , specializing in immunology and hepatic diseases. His work spans rheumatoid arthritis, primary biliary cholangitis, and cancer biology, with collaborations across multiple disciplines including medical proteomics and developmental biology. Research Focus: Investigating endogenous retroelement activation in autoimmune pathogenesis (2025) Exploring bile acid therapies for liver disease and cognitive dysfunction (2023) Developing molecular tools for stratifying liver disease progression (2021-2016) Key Collaborations: Active in multi-institutional studies, particularly in chemokine signaling in cancer metastasis (2021) and kinase-targeted therapies in inflammation (2021).

• Immunology
• Rheumatology
• Hepatology
• +۳ مورد دیگر

Professor Miguel Branco serves as Professor of Genome Regulation and Centre Lead for Genomics and Child Health at the Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London. His research centers on epigenetic mechanisms governing transposable elements and their functional impact on genome stability, development, and disease pathogenesis. He holds a Biochemistry degree from the University of Lisbon and completed his PhD at the MRC Clinical Sciences Centre in London under Prof. Ana Pombo, investigating genome spatial organization. Postdoctoral work with Prof. Wolf Reik at the Babraham Institute focused on DNA hydroxymethylation in embryonic stem cells. His laboratory employs epigenomic profiling and molecular techniques to dissect dual roles of transposable elements: (1) repression mechanisms in somatic tissues and developmental contexts, and (2) evolutionary co-option as gene regulatory elements. Key investigations include TE-derived enhancer functions in placental evolution and oncogenesis, with emphasis on DNA modification pathways and stem cell models. Publication analysis reveals consistent focus on transposable element regulation through epigenetic mechanisms, particularly DNA methylation/hydroxymethylation dynamics. Research spans cancer biology (leukemia enhancer formation), developmental systems (trophoblast/placental models), and fundamental genome regulation principles using embryonic stem cell paradigms. His scientific recognition includes: Next Generation Fellowship from the Centre for Trophoblast Research (University of Cambridge) Sir Henry Dale Fellowship from the Wellcome Trust and Royal Society He supervises PhD candidates including Darren Taylor and leads research funded through competitive fellowships. The lab maintains active collaborations within the Blizard Institute and international epigenetics consortia, with ongoing projects examining TE contributions to enhancer landscapes in mammalian trophoblast lineages. Housed within the Blizard Institute's Centre for Genomics and Child Health, the Branco Lab operates as part of QMUL's Centre for Epigenetics. The team investigates TE regulation across developmental timepoints using multi-omics approaches, with particular emphasis on primate and rodent placental models to understand evolutionary and pathological implications.

• Epigenetics
• Transposable Elements
• Genome Regulation
• +۳ مورد دیگر

Fotios Koumpouras, MD, is an Associate Professor of Medicine (Rheumatology) at Yale School of Medicine, where he serves as Director of the Yale Lupus Program and Director of Education and Training in Rheumatology. His expertise lies in systemic lupus erythematosus (SLE), clinical trials, and rheumatology education. He leads a multidisciplinary team focusing on SLE care, research, and wellness, and has developed innovative programs such as the Yale Rheumatology-Biobank and the rheumatology-dermatology clinic. Dr. Koumpouras is actively involved in major SLE clinical trials, including those evaluating novel biologics and therapeutic targets. Education: BS, University at Albany, 1994 MD, St. George’s University School of Medicine, 2000 Residency, Stony Brook University Hospital, 2003 Chief Residency, Stony Brook University Hospital, 2004 Fellowship, Yale University School of Medicine, 2006 Investigative Fellowship, Yale University, 2007 Research Interests: Dr. Koumpouras focuses on SLE pathogenesis, biomarkers, and clinical trial development. His work includes studies on interferons, cytokines, and novel therapeutic targets such as DNASE1/DNASE1L3 biologics. He collaborates with immunologists and dermatologists to explore cutaneous lupus and stromal niches. Awards: Physician Scientist Development Award (American College of Rheumatology, 2006) Resident of the Year (Stony Brook University, 2003) Patients' Choice 5th Anniversary Award (2015) Clinical Trials: Dr. Koumpouras leads trials evaluating therapies for SLE, including VIBRANT (VIB4920 for Lupus Nephritis) and the Yale Lupus Biorepository. He is part of the Lupus Clinical Investigators Network (LuCIN), accelerating new therapies. Labs/Teams: His team includes collaborations with immunologists (e.g., Akiko Iwasaki) and rheumatology researchers. The Yale Lupus Program integrates clinical care, research, and education.

• Systemic Lupus Erythematosus (SLE)
• Rheumatology
• Clinical Trials
• +۵ مورد دیگر

Sasha Zhernakova is a Professor at the University of Groningen's Faculty of Medical Sciences, affiliated with the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI) and Translational Immunology Groningen (TRIGR). Her research focuses on gut microbiome dynamics, genetics, and their implications for human health, particularly metabolic and immune-related conditions. Education & Affiliations: Primary affiliation: Faculty of Medical Sciences/UMCG Research groups: 3GI and TRIGR Research Interests: Her work explores the interplay between the gut microbiome and host genetics, with emphasis on metabolic health, inflammatory diseases, and geographic influences on microbial diversity. Key areas include genome-wide association studies (GWAS), microbiome composition across lifespans, and translational immunology applications. Articles Trends: Recent publications highlight population-based studies on microbiome-metabolic health links, global genetic structures of gut microbes, and viral elements in Faecalibacterium species. Her work bridges basic science with clinical implications, emphasizing translational applications. Awards: Recipient of the Gamow Award (2022), recognizing outstanding contributions to molecular biology and genetics. Advising & Grants: Supervised 14 PhD/MSc students, including Marjolein Klaassen's thesis on inflammatory bowel diseases. Secured grants for pediatric allergy research (e.g., 1.5M EUR funding in 2024). Labs & Teams: Leads interdisciplinary teams at 3GI and TRIGR, collaborating internationally on microbiome projects. Active in initiatives like the Human Microbiome Action Consortium.

• Gut Microbiome
• Genetics
• Microbiome
• +۳ مورد دیگر