معرفی
Jennifer Erwin is an Assistant Professor of Neurology and Neuroscience and an Investigator at the Lieber Institute for Brain Development (LIBD) in Baltimore, MD. Her research integrates molecular neuroscience with human stem cell models and computational approaches to understand the role of retroelements and somatic mosaicism in brain development and disease.
Her research focuses on developmental neuroscience, cellular and molecular mechanisms in the brain, and the neurobiology of disease. Specifically, she investigates how gene-by-environment interactions contribute to psychiatric and neurodegenerative disorders through the activity of retroelements such as LINE-1 and SVA, which can cause somatic mosaicism in neurons. This work has implications for understanding schizophrenia, aging, and rare disorders like X-linked Dystonia Parkinsonism.
The Erwin lab employs a multidisciplinary approach combining human induced pluripotent stem cell (iPSC) models, postmortem human brain tissue analysis, and bioinformatics to uncover novel molecular pathways. The overarching goal is to identify targets for neuroprotective therapies in brain disorders where genetic and environmental factors converge.
She is affiliated with the Neuroscience Training Program, indicating her involvement in mentoring graduate students. While no specific awards or publications are listed in the profile, her research program is centered on innovative mechanisms in brain disease, suggesting active grant support and scholarly output.
Jennifer Erwin leads a research laboratory at the Lieber Institute for Brain Development, located at 855 N. Wolfe Street, Baltimore, MD, in the Rangos Building. The lab focuses on retrotransposon biology and its impact on neural diversity and disease susceptibility.
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