معرفی
Nicola Micali is an Associate Research Scientist in the Department of Neuroscience at the Yale School of Medicine, part of Yale University. He leads research in the Rakic Lab, focusing on neural stem cell biology, corticogenesis, and the molecular mechanisms underlying brain development across species. His work integrates molecular genetics and developmental biology to study radial glial cells, neural fate specification, and species-specific differences in brain development.
Dr. Micali holds a PhD in Genetics, Molecular, and Cellular Biology from the University of Milan and completed postdoctoral training at the Lieber Institute for Brain Development (LIBD) and the San Raffaele Scientific Institute. His research interests include neurodevelopmental disorders modeled using pluripotent stem cells, transcriptomic analysis of neocortical development, and the role of growth factors like FGF2 and BMPs in neural differentiation.
He collaborates with institutions such as the LIBD, Johns Hopkins Medical School, and AstraZeneca Neuroscience, advancing translational research in schizophrenia and autism. His studies on primate brain evolution, radial glial cell metabolism, and neural stem cell fate progression have contributed to understanding cortical disorders and evolutionary biology.
Key projects include analyzing regional brain specification in rodents, non-human primates, and humans, and dissecting the genetic programs driving neural stem cell differentiation. His work bridges basic science and clinical applications, aiming to uncover mechanisms underlying neurological conditions and improve disease modeling strategies.
