معرفی
Keri Martinowich is a Senior Investigator and Director of Translational Neuroscience at the Lieber Institute for Brain Development (LIBD) and an Associate Professor in the Departments of Psychiatry and Neuroscience at Johns Hopkins University School of Medicine. She leads an interdisciplinary research program focused on understanding molecular and genetic mechanisms underlying neuropsychiatric disorders such as schizophrenia, depression, PTSD, and autism.
Her research integrates animal models with human postmortem brain studies, using advanced techniques including single-nucleus and spatially resolved transcriptomics, viral transgenesis, and circuit-level manipulation to identify cell-type-specific gene expression patterns and their functional roles in behavior. Her lab develops open-access tools for data exploration and emphasizes reproducibility and data sharing.
Dr. Martinowich's recent publications reveal trends across cognitive and computational neuroscience, with a strong emphasis on neural circuits, gene regulation, and translational psychiatry. Her work spans molecular neuroscience, systems-level analysis, and behavior, often focusing on BDNF signaling, fear, social behavior, and cortical-subcortical circuitry. She actively mentors graduate students and postdoctoral researchers, many of whom have advanced to PhD programs and faculty positions.
- Electrophysiology and attention circuits (locus coeruleus–prefrontal cortex)
- Spatial transcriptomics in human brain regions (locus coeruleus, prefrontal cortex)
- BDNF mechanisms in maternal behavior, aggression, and fear memory
- Cell-type-specific signatures in reward and stress circuits
She has no explicitly listed scientific awards in the provided text, but her leadership, high-impact publications, and NIH-level research program indicate significant recognition in the field.
Dr. Martinowich advises a diverse team of graduate students, postdocs, and research associates affiliated with programs in Neuroscience, BCMB, CMM, and Human Genetics at Johns Hopkins. Her lab has secured substantial funding to support cross-species studies integrating molecular profiling with behavioral neuroscience. She collaborates extensively with experts in bioinformatics, genomics, and psychiatry.
Her laboratory at the Lieber Institute for Brain Development in Baltimore is a hub for translational neuroscience, combining wet-lab experimentation with computational analysis. The team develops interactive dashboards for public data access and focuses on identifying novel therapeutic targets for psychiatric disorders. Current directions include refining spatial transcriptomic methods and reverse-translating human genetic findings into causal animal models.
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