جست‌وجوی استاد و پژوهشگر

Loren Williamsمشاهده پروفایل

استاد

• Biochemistry
• Origins of Life
• Ribosome Evolution
• +۳ مورد دیگر

Loren Williams is a Professor at the School of Chemistry and Biochemistry at Georgia Institute of Technology. He leads the Williams Lab, focusing on RNA/DNA folding, ribosome origins, and chemical evolution. He is Director of the NASA-funded Center for the Origins of Life (COOL) and former Director of the RiboEvo Center. Education : B.Sc. in Chemistry, University of Washington (1981) Ph.D. in Physical Chemistry, Duke University (1985) NIH Postdoctoral Fellow under Alex Rich, MIT Biology Department (1988-1992) Research Interests center on reconstructing ancient ribosomal structures through phylogeny, evolutionary theory, biophysics, and bioinformatics. He explores how sequence, covalent damage, anti-cancer drugs, and proteins modulate RNA/DNA folding. His work bridges early Earth environments with life’s emergence, emphasizing water’s role and metal ion interactions. Article Trends (2018-2025): Interdisciplinary focus on ribosome evolution (e.g., Asgard archaea, LUCA), prebiotic chemistry (depsipeptides, thioesters), and molecular interactions (RNA-metal, G-quadruplexes). Recurring themes include combinatorial chemical systems, evolutionary modeling, and astrobiological implications. Scientific Awards : NSF CAREER Award (1995-1998) Sigma Xi Best Paper (1997) Petit Institute "Above and Beyond" Awards (2012, 2021) Georgia Tech Faculty Mentor Awards (2013, 2022) AAAS and ISSOL Fellowships Vasser Woolley Instruction Award (2019) Advising & Grants : Mentored students like Chiaolong Hsiao (Sigma Xi Best Thesis 2009). Leads NASA-funded initiatives (COOL, PCE3) and explores SARS-CoV-2 testing kit design.

Ronald S. Johnsonمشاهده پروفایل

استاد

• RNA polymerase mechanisms
• Transcription reaction mechanisms
• Gene expression regulation
• +۳ مورد دیگر

Ronald S. Johnson is a Professor in the Department of Biochemistry and Molecular Biology at the Brody School of Medicine, East Carolina University. His research program focuses on the molecular mechanisms of transcription by Escherichia coli RNA polymerase, employing advanced biochemical and biophysical techniques to investigate gene expression regulation. Dr. Johnson's research interests center on transcription reaction mechanisms, with particular emphasis on RNA polymerase function. His laboratory investigates structural, thermodynamic, and kinetic parameters across all stages of transcription including promoter binding, initiation, promoter clearance, elongation, and termination. Current work focuses on nucleotide addition cycles and transcription fidelity mechanisms. Analysis of recent publications reveals a consistent focus on RNA polymerase kinetics using fluorescence spectroscopy and rapid kinetic methods. The research trajectory shows progression from fundamental binding studies to increasingly sophisticated analyses of conformational changes during nucleotide incorporation cycles, with significant contributions to understanding transcriptional fidelity mechanisms. Dr. Johnson employs a multidisciplinary approach combining: Fluorescence spectroscopy Stopped-flow and quench-flow kinetics Enzymatic assays Protein chemistry Molecular biology techniques His laboratory maintains active research in transcriptional mechanisms with regular publications in high-impact journals including the Journal of Molecular Biology and PLoS One , demonstrating sustained productivity in elucidating fundamental biochemical processes.

Matjaz Barboricمشاهده پروفایل

پژوهشگر

• Transcription Elongation
• RNA Polymerase II
• Gene Expression Regulation
• +۷ مورد دیگر

Matjaz Barboric is a University Researcher in the Department of Biochemistry and Developmental Biology at the University of Helsinki, where he serves as a Supervisor in the Doctoral Programme in Biomedicine. His research is supported by multiple active projects funded by the Academy of Finland, Cancer Foundation, Sigrid Jusélius Foundation, and Magnus Ehrnrooths Foundation, with research extending through 2028. Dr. Barboric's research program focuses on the fundamental mechanisms of metazoan gene transcription by RNA polymerase II, particularly investigating regulatory factors that modulate transcription at the elongation level. His laboratory studies key cyclin-dependent kinases that stimulate RNAPII elongation and phosphorylate the C-terminal domain of Rbp1 at Serine 2. Using biochemical, genetic, and systems biology approaches, his team explores how transcription elongation connects to pre-mRNA processing events like alternative splicing through Ser2-P CTD modification. A critical aspect of his work examines how deregulation of RNAPII elongation control contributes to cancer development and investigates the significance of transcription elongation kinases in embryonic development. Analysis of Dr. Barboric's publication record spanning over two decades reveals consistent focus on transcriptional regulation mechanisms, with recent work increasingly connecting fundamental transcription processes to cancer biology. His research demonstrates strong interdisciplinary connections between basic molecular mechanisms and clinical applications, particularly in identifying how transcriptional dysregulation contributes to disease states and potential therapeutic targets. Dr. Barboric currently leads multiple research projects including 'Combinatorial targeting of transcriptional kinases in cancer' funded by the Academy of Finland (2024-2028), multiple Cancer Foundation projects (2024-2026), and the M&GC. Ehrnrooth Foundation project (2025). He serves as a supervisor for doctoral students in the Biomedicine program, with documented supervision of research on 'Regulation of Pol II polymerase transcriptional response to DNA damage by RBM7 and P-TEFb' in 2020.

• Molecular Biology
• Epigenetics
• Proteomics
• +۳ مورد دیگر

Tim Liebner serves as a Postdoctoral Research Fellow at the Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, within the Choudhary Group. His work focuses on molecular mechanisms of epigenetic regulation and cardiac physiology. His research spans epigenetics , chromatin biology , and cardiovascular molecular mechanisms , with emphasis on histone modifications, enhancer function, and HDAC6 signaling pathways. Key investigations include acetylation dynamics in transcription regulation and HDAC6's role in cardiac myofibril mechanics. Recent publications in Nature Communications , Nature Genetics , and Journal of Clinical Investigation demonstrate significant contributions to understanding transcriptional control and heart function. Collaborative work includes international teams studying p300/CBP complexes and cardiac diastolic mechanisms. Laboratory work is conducted within the Choudhary Group at CPR, leveraging proteomics and molecular biology approaches to dissect protein modification networks in disease contexts.

• Developmental Biology
• Neurobiology
• RNA Regulation
• +۵ مورد دیگر

Eugenia Olesnicky is a Professor in the Department of Biology within the College of Letters, Arts & Sciences at the University of Colorado Colorado Springs. Her academic journey includes a Ph.D. in Developmental Genetics from New York University (2007), post-doctoral training at Princeton University's Department of Molecular Biology (2009-2011), and additional post-doctoral work at the University of Colorado Denver Health Sciences Center's Department of Craniofacial Biology (2007-2009). Dr. Olesnicky's research focuses on the fundamental question of how neurons establish and maintain their specialized structures and functions. Her work centers on post-transcriptional gene regulation mechanisms, particularly mRNA localization and local protein translation, which play critical roles in neuronal morphogenesis and neural circuit formation. Using Drosophila as a primary model system, her lab investigates RNA binding proteins, with special emphasis on the splicing factor Caper, to understand their roles in neurodevelopment. Analysis of her publication record from 2004-2023 reveals a consistent research trajectory in RNA regulation and neural development. Her work spans from basic mechanisms of transcription and DNA adducts to sophisticated analyses of RNA-binding proteins in neuronal development across multiple model organisms. Recent publications demonstrate an increasing focus on the multifaceted roles of the Caper protein in neuromuscular development, reproductive output, and aging processes. Dr. Olesnicky actively mentors students at both undergraduate and graduate levels, requiring foundational knowledge in molecular biology and genetics. Her lab website lists current research projects investigating RNA binding proteins necessary for neuronal morphogenesis, utilizing molecular genetic and biochemical approaches, behavior analyses, and confocal microscopy.

• Genome Organization
• Epigenetics
• Chromatin Structure
• +۵ مورد دیگر

Dr. Andrew Klocko is an Assistant Professor in the Department of Chemistry & Biochemistry within the College of Letters, Arts & Sciences at the University of Colorado Colorado Springs. His research program focuses on understanding the three-dimensional organization of the genome in the filamentous fungus Neurospora crassa , with particular emphasis on how heterochromatic regions form a distinct bundle and how this architecture influences gene regulation. Dr. Klocko's research interests center on genome organization, chromatin structure, and epigenetic regulation. His lab investigates the macromolecular components that establish and maintain the non-stochastic organization of the Neurospora genome, where heterochromatic regions strongly interact to form a bundle while euchromatic regions loop out. This work has implications for understanding fundamental principles of eukaryotic genome architecture and gene expression control. His publication record shows consistent output since 2009, with recent high-impact papers in journals including PNAS, BMC Genomics, and FEMS Microbiology Reviews. The research trajectory demonstrates a progression from molecular mechanisms of transcription regulation to sophisticated analyses of three-dimensional genome organization. As an active researcher with publications through 2025, Dr. Klocko maintains a productive laboratory investigating fundamental questions in genome biology using Neurospora crassa as a model system. His work bridges molecular biology, genetics, and genomics to uncover principles of nuclear architecture that may be conserved across eukaryotic organisms.

Samantha Dealمشاهده پروفایل

استادیار

• Neurobiology
• Genetics
• Developmental Biology
• +۵ مورد دیگر

Dr. Samantha Deal is an Assistant Professor of Biology in the Department of Biology at Mercer University's College of Liberal Arts and Sciences, where she joined in August 2025. Her research focuses on understanding the role of mitochondria in sleep disruption during aging using the fruit fly (Drosophila melanogaster) as a model organism. Education: IRACDA Postdoctoral Fellow, University of Pennsylvania Ph.D. in Developmental Biology, Baylor College of Medicine B.S., North Carolina State University Dr. Deal's research centers on the intersection of mitochondria, sleep, and aging. She investigates how mitochondrial dysfunction contributes to age-related sleep decline, with particular focus on the mitochondrial polymerase PolG1. Her lab also explores rare human mitochondrial disease genes using Drosophila models to understand their functional consequences. She teaches introductory biology, development, genetics, and neurobiology courses. Dr. Deal's publication record shows a consistent focus on using Drosophila models to study neurodevelopment, neurodegeneration, and the genetic basis of sleep and behavior. Her work bridges basic genetic research with potential clinical applications in understanding rare human diseases. Her laboratory, the Deal Lab, employs various techniques including Drosophila Activity Monitoring systems and fluorescent reporters to study mitochondrial structure and function in relation to sleep. The lab's research has implications for understanding age-related sleep disorders and mitochondrial diseases.

Holger Bierhoffمشاهده پروفایل

دانشیار

• Epigenetics
• Aging Research
• Non-coding RNA
• +۶ مورد دیگر

Holger Bierhoff serves as an Associate Group Leader at Friedrich Schiller University Jena with an associated position at the Leibniz Institute on Aging (FLI), operating from the Center for Molecular Biomedicine (CMB). His research group maintains a guest status collaboration with FLI while being primarily based at the university. Professor Bierhoff's research focuses on epigenetics of aging, specifically investigating how non-coding RNAs form RNA:DNA triplex structures to regulate chromatin landscape. His lab has developed novel molecular tools to detect and characterize these triplex structures genome-wide, examining how they compete with protein binding or alternative nucleic acid structures at target sites. Current work explores connections between ribosome biogenesis, nucleolar function, and aging processes using human and mouse cell models. His publication record shows consistent high-impact output, with multiple significant papers in 2024 including research on RNA:DNA triplexes as epigenetic communication mechanisms, rRNA synthesis and longevity in C. elegans, and breast cancer mechanisms. His work appears in prestigious journals such as Nature Communications, Cell Reports, and Nucleic Acids Research. Professor Bierhoff leads two major funded projects: AgingComb (funded by European Regional Development Fund) investigating genomic alterations through high-throughput DNA analysis, and 'Nucleolus as a target' (funded by European Social Fund) developing nucleolar changes as biomarkers for healthy aging. Both projects involve interdisciplinary collaborations between university researchers and clinical partners. His lab maintains active supervision of doctoral, master's, and bachelor students, creating a collaborative research environment focused on cutting-edge epigenetic mechanisms in aging. The group is embedded within the Zentrum für Alternsforschung Jena (ZAJ) and the Leibniz Research Alliance Resilient Ageing, providing students with access to advanced facilities and interdisciplinary networks.

• Epigenetics
• Chromatin Biology
• Environmental Epigenetics
• +۴ مورد دیگر

Daphne Selvaggia Cabianca is a Group Leader at the Cabianca Lab , affiliated with Helmholtz Munich under the Functional Epigenetics (IFE) group . Her research focuses on understanding how environmental inputs modulate chromatin state, spatial organization, and function using the model organism C. elegans . Research Interests Epigenetic responses to environmental stress Chromatin 3D organization and gene regulation Nutrient and temperature effects on chromatin Stress memory mechanisms Key Techniques CRISPR-Cas9 genetic editing ChIP, DamID, ATACseq RNAseq and organismal stress assays Her work explores the interplay between environmental stimuli and chromatin dynamics across life stages, from development to aging. This research has implications for diseases like obesity, type 2 diabetes, and cancer with strong environmental links. Recent publications highlight her contributions to understanding fasting-induced chromatin reorganization, ferroptosis suppression in neuronal development, and environmental stress memory mechanisms. Collaborative lab members include doctoral researchers and postdocs working on various aspects of chromatin biology and C. elegans genetics. Lab Members Iratxe Estivariz (Postdoc) Fernanda Pabst (Doctoral Researcher) Carole Zaratiegui (Doctoral Researcher) Yuri D'Alessio (Doctoral Researcher) Lorenz Pudelko (Doctoral Researcher)

• Structural Biology
• Chemokine Signaling
• Macrophage Migration Inhibitory Factor (MIF) Family
• +۸ مورد دیگر

Dr. Elias Lolis is a Professor of Pharmacology at Yale School of Medicine with multiple affiliations across Yale University including the Biochemistry, Quantitative Biology, Biophysics and Structural Biology program; Developmental Therapeutics; Yale Cancer Center; and the Yale Combined Program in the Biological and Biomedical Sciences (BBS). He serves as the Faculty Director of the Office for Postdoctoral Affairs and his department's Director of Graduate Studies. Dr. Lolis received his BA in Chemistry from Columbia College and PhD in Chemistry from MIT, with postdoctoral training at Rockefeller University. His research focuses on understanding the biology, structure, mechanism of action, and pharmacology of proteins in physiology and pathophysiology, particularly chemokines and the macrophage migration inhibitory factor (MIF) family in disease contexts. His lab employs a multidisciplinary approach including structural biology (X-ray crystallography and NMR), molecular dynamics, high throughput screening, mutational analysis, yeast genetics, and CRISPR/Cas9 mouse models. Specific projects include: Chemokine-chemokine receptor (GPCR) structures High throughput screening for small molecule agonists and antagonists Yeast genetics to study chemokine-receptor interactions Mechanism of receptor activation for macrophage migration inhibitory factor Identification of MIF substrates and structure of MIF-ligand complexes Dr. Lolis has made significant contributions to the field, receiving awards including the Pharmaceutical Manufacturers Association Faculty Development Award, the Donaghue Young Investigator Award, and the GlaxoWellcome Award in Drug Discovery. He is the founder of the Yale Macromolecular X-ray Facility and co-founder of the Yale Keck Bioinformatics Resource. As an educator and mentor, Dr. Lolis has trained more than 25 postdoctoral associates, seven PhD students, and numerous undergraduate and minority students. He serves as his department's Director of Graduate Studies and is actively involved in diversity and inclusion initiatives at Yale. His research shows strong translational potential with applications to cancer, inflammation, and infectious diseases.

• V(D)J recombination
• Somatic hypermutation
• Antibody Diversity
• +۵ مورد دیگر

David G. Schatz is the Waldemar Von Zedtwitz Professor of Immunobiology and Professor of Molecular Biophysics and Biochemistry at Yale University, where he serves as Chair of the Department of Immunobiology at the Yale School of Medicine. His research focuses on the molecular mechanisms that generate diversity in the immune system's antigen receptors, particularly V(D)J recombination and somatic hypermutation. Dr. Schatz is best known for the discovery of RAG1 and RAG2 proteins, which revolutionized our understanding of how the adaptive immune system generates its extraordinary receptor diversity. Dr. Schatz's research interests include: Mechanisms of V(D)J recombination Somatic hypermutation Evolutionary origins of RAG proteins Antibody diversity and formation Gene rearrangement in lymphocytes Molecular biology of immune receptor assembly Analysis of Dr. Schatz's recent publications (2021-2026) reveals a sustained and growing impact in immunology. His work spans structural biology, evolutionary studies, and molecular mechanisms, with particular emphasis on RAG protein function, regulation of somatic hypermutation, and the evolutionary history of the adaptive immune system. His research has significant implications for understanding immune disorders, lymphoid cancers, and the fundamental processes of immune receptor diversity, with numerous publications appearing in top journals including Nature, Science, and Nature Reviews Immunology. Dr. Schatz has received numerous prestigious awards including: Paul Ehrlich and Ludwig Darmstaedter Prize (2023) Election to the National Academy of Medicine (2019) Election to the National Academy of Sciences (2018) Fellow of the American Association for the Advancement of Science (2016) Member of the American Academy of Arts and Sciences (2014) As an educator, Dr. Schatz has served as Director of Graduate Studies and Graduate Admissions for Immunobiology and as a member of the Executive Committee of the Biological and Biomedical Sciences (BBS) Program. He has been active as an editor and reviewer, serving as Co-Editor of the journal Immunity and on editorial boards of multiple journals. His laboratory continues to be highly productive, with ongoing projects examining the molecular details of RAG function, the regulation of somatic hypermutation, and the evolutionary history of the adaptive immune system, maintaining numerous collaborations both within Yale and internationally.

• RNA-Protein Complexes
• Gene Expression
• Noncoding RNAs
• +۷ مورد دیگر

Joan Steitz is the Sterling Professor of Molecular Biophysics and Biochemistry at Yale School of Medicine, where she has made groundbreaking contributions to RNA biology. She leads the Steitz Lab, which is affiliated with multiple Yale research centers including the Yale Cancer Center, Yale Stem Cell Center, and the Center for RNA Science and Medicine. Yale School of Medicine, Department of Molecular Biophysics and Biochemistry (Primary) Yale Cancer Center Yale Stem Cell Center Yale Combined Program in the Biological and Biomedical Sciences (BBS) Center for RNA Science and Medicine Dr. Steitz earned her BS from Antioch College (1963) and PhD from Harvard University (1967), followed by postdoctoral work at the Medical Research Council Laboratory of Molecular Biology in Cambridge, England. She joined Yale as an assistant professor and progressed to become a Sterling Professor, one of Yale's highest academic honors. Her research focuses on RNA-protein complexes, particularly small nuclear ribonucleoproteins (snRNPs) that play critical roles in pre-mRNA splicing. The lab investigates how these complexes recognize intron signals and assemble into functional spliceosomes. Recent work has explored stress-induced transcriptional readthrough, RNA stability mechanisms involving poly(A) tails, and the functions of viral noncoding RNAs from herpesviruses. Analysis of Dr. Steitz's recent publications reveals a strong emphasis on RNA structure-function relationships, viral-host interactions, and the molecular mechanisms of RNA processing. Her work spans structural biology, virology, and molecular genetics, with applications to understanding human diseases including cancer. Warren Alpert Prize (2021) Wolf Prize in Medicine (2021) Watson Prize (2021) Medal Prize Lecture (2021) Honorary Doctor of Science (2021) Dr. Steitz actively mentors students and postdocs, with numerous trainees appearing as co-authors on her publications. Her lab maintains strong collaborations across Yale and with international researchers, as evidenced by her extensive publication record. She has also been a prominent advocate for gender diversity in STEM fields, co-authoring influential papers on improving representation of women in science. The Steitz Lab maintains active research programs in RNA structure, splicing mechanisms, viral noncoding RNAs, and stress responses, with ongoing projects examining how RNA-protein interactions govern gene expression in both normal and disease states.

Juri Rappsilberمشاهده پروفایل

استاد

• Proteomics
• Mass Spectrometry
• Protein Structure
• +۴ مورد دیگر

Prof. Juri Rappsilber is a Professor at the Technical University of Berlin's Institute of Biotechnology and Group Leader of Research Unit E in the UniSysCat Cluster of Excellence. His affiliations include Visiting Professorship at Kyoto University (2017, JSPS Fellow) and Senior Research Fellowships at the Wellcome Trust (2009-2019). He leads the Rappsilber Laboratory, focused on developing mass spectrometry technologies to study protein structure and interactions. Research interests center on proteomics , crosslinking mass spectrometry , and protein-network analysis . Key areas include: Functional protein networks through co-regulation studies Chromatin dynamics and mitotic chromosome composition In-cell structural proteomics integrating deep learning Development of bioorthogonal catalysis for medical applications His publication record demonstrates consistent output in high-impact journals, with recent work emphasizing: Structural mechanisms of protein complexes (γ-tubulin, condensin) Crosslinking MS methodology innovation and error control Integration of AI with experimental structural biology Catalytic processes in bioinorganic systems Awards and honors: EMBO Membership (2021) BSPR Lectureship (2014) Einstein Professorship (2011) Wellcome Trust Senior Research Fellow (2009-2019) Marie Curie Excellence Fellow (2005-2010) He actively advises doctoral students, including DAAD Hilde-Domin Program recipients, and secures substantial funding through ERC Synergy Grants, Wellcome Trust awards, and national initiatives. The lab focuses on developing anti-cancer therapeutics and sustainable chemistry solutions while pursuing Green Lab Certification.

• Cryo-electron microscopy
• Virus Structure and Assembly
• Bacteriophages
• +۵ مورد دیگر

Dr. Terje Dokland is a Professor in the Department of Microbiology at the University of Alabama at Birmingham (UAB), where he has been a faculty member since 2004. He also holds appointments as Senior Scientist at the O'Neal Comprehensive Cancer Center (since 2022) and as Scientist at the Center for Biophysical Sciences and Engineering (since 2008). Dr. Dokland established and directs the UAB cryo-EM facility, which is part of the O'Neal Comprehensive Cancer Center's Structural Biology Shared Resource and houses advanced equipment including a Thermo Fisher Glacios 2 microscope and a Talos F200C microscope. Dr. Dokland received his Bachelor's and Master's degrees in biology from the University of Oslo, Norway, followed by a PhD at the European Molecular Biology Laboratory in Heidelberg, Germany (1989-1993). He completed postdoctoral training at Purdue University (1994-1998) before holding an independent research position at the Institute of Molecular Agrobiology in Singapore (1998-2004). His research focuses on the structure and function of bacteriophages, particularly their role in mobilizing pathogenicity islands in Staphylococcus aureus, and more recently on the structure of the streptococcal ribosome. His laboratory specializes in applying cryo-electron microscopy to determine high-resolution structures of viral components and bacterial systems. Recent publications (2023-2025) demonstrate continued productivity in structural virology, with multiple papers in high-impact journals describing the architecture of bacteriophage components and their interactions with bacterial hosts. His work has important implications for understanding bacterial pathogenesis and developing novel antimicrobial strategies. Graduate School Dean's Award for Excellence in Mentorship (2011) ASM distinguished lecturer (2017-2019) Organizer of the FASEB Virus Structure and Assembly Conference (2022) Permanent member of the MSFC study section (2013-2019) Dr. Dokland actively mentors graduate students and postdoctoral researchers, serving on numerous dissertation committees across multiple departments. His grant portfolio includes continuous NIH funding since 2008, with current support for ribosome structure research and cryo-EM facility operations. He teaches advanced courses in structural biology and cryo-electron microscopy, contributing significantly to UAB's graduate training programs in microbiology and structural biology.

• RNA virology
• Coronavirus research
• Viral replication mechanisms
• +۴ مورد دیگر

Professor Yu Chen is a Principal Investigator and Professor at Wuhan University's College of Life Sciences, leading research at the State Key Laboratory of Virology since December 2016. With a PhD in Microbiology from Wuhan University (2003-2009), Dr. Chen has established a prominent research program focused on RNA virus molecular mechanisms, particularly coronaviruses. Research interests center on viral RNA methylation processes, coronavirus replication strategies, and host-pathogen interactions. The lab investigates SARS-CoV-2 variants, viral entry mechanisms through ACE2 receptors, and development of broad-spectrum antivirals targeting RNA modification enzymes. Recent work examines interferon signaling pathways and adenovirus-related pediatric hepatitis. Publication analysis reveals consistent high-impact output with 34 documented works, including 15 publications since 2020 in journals such as Nature, PNAS, and Cell Insight. Research demonstrates strong translational impact in SARS-CoV-2 diagnostics, antiviral development, and viral transmission mechanisms. Dr. Chen serves as peer reviewer for prestigious journals including Nature Biotechnology and Nature Communications. The lab maintains active collaborations across virology research groups, with consistent co-authorship patterns indicating productive international partnerships. As Principal Investigator at the State Key Laboratory of Virology, Dr. Chen oversees research utilizing advanced BSL-3 facilities for working with live viruses, genomics platforms, and structural biology resources. The lab trains approximately 8-12 graduate students working on interconnected projects in RNA virology.