معرفی
Dr. Andrew Klocko is an Assistant Professor in the Department of Chemistry & Biochemistry within the College of Letters, Arts & Sciences at the University of Colorado Colorado Springs. His research program focuses on understanding the three-dimensional organization of the genome in the filamentous fungus Neurospora crassa, with particular emphasis on how heterochromatic regions form a distinct bundle and how this architecture influences gene regulation.
Dr. Klocko's research interests center on genome organization, chromatin structure, and epigenetic regulation. His lab investigates the macromolecular components that establish and maintain the non-stochastic organization of the Neurospora genome, where heterochromatic regions strongly interact to form a bundle while euchromatic regions loop out. This work has implications for understanding fundamental principles of eukaryotic genome architecture and gene expression control.
His publication record shows consistent output since 2009, with recent high-impact papers in journals including PNAS, BMC Genomics, and FEMS Microbiology Reviews. The research trajectory demonstrates a progression from molecular mechanisms of transcription regulation to sophisticated analyses of three-dimensional genome organization.
As an active researcher with publications through 2025, Dr. Klocko maintains a productive laboratory investigating fundamental questions in genome biology using Neurospora crassa as a model system. His work bridges molecular biology, genetics, and genomics to uncover principles of nuclear architecture that may be conserved across eukaryotic organisms.
