جستجوی استاد راهنمای دانشگاهی

Xuefei Huangمشاهده پروفایل

استاد

• Carbohydrate Chemistry
• Molecular Imaging
• Nanoparticle Technology
• +۳ مورد دیگر

Xuefei Huang is a Professor in the Departments of Biomedical Engineering and Chemistry at Michigan State University (MSU), serving as Associate Chair for Research in the Chemistry Department. He earned his Ph.D. from Columbia University and previously worked at the University of Toledo. His research integrates synthetic chemistry, biology, and engineering to develop advanced tools for disease diagnosis and treatment, with a focus on carbohydrate chemistry, molecular imaging, and targeted drug delivery. Education: Ph.D., Columbia University Bachelor's degree, University of Science and Technology of China Research Interests: His work emphasizes the synthesis and application of carbohydrates, particularly in developing vaccines, anti-cancer therapies, and diagnostic nanoparticles. Key areas include glycoconjugate vaccines, nanoparticle-based drug delivery systems, and immunotherapies targeting cell surface carbohydrates. The Huang Lab employs interdisciplinary approaches, combining organic synthesis, molecular imaging, and virology. Research Trends in Publications: Recent work focuses on carbohydrate-based vaccines (e.g., SARS-CoV-2, Salmonella), glyco-nanoparticle design for imaging and surgery guidance, and structure-activity relationships in heparin/heparan sulfate oligosaccharides. Labs & Teams: The Huang Lab collaborates across disciplines to advance biomedical innovations, with a focus on translational applications in oncology, infectious diseases, and nanotechnology.

C. Nick Paceمشاهده پروفایل

استاد

• Protein Structure
• Biochemistry
• Molecular Biology
• +۴ مورد دیگر

C. Nick Pace is a Distinguished Professor and Regents Professor at Texas A&M University’s School of Medicine, affiliated with the Department of Molecular & Cellular Medicine. He joined the faculty in 1968 and has held visiting roles at Osaka University (1992) and the MRC Centre in Cambridge (1982). His research focuses on protein structure-function relationships, including how amino acid sequences influence folding, stability, solubility, and biological activity. Key themes include predicting protein behavior from sequences and understanding denatured state interactions. Education: PhD in Biochemistry, Duke University (1966) BS in Chemistry, University of Utah (1962) Research emphasizes protein ionization, pH effects, and engineering solutions to enhance protein solubility and stability. Recent work explores beta-turn optimization and long-range interactions in denatured proteins. Over 50 years of contributions to structural biology include pivotal studies on ribonuclease Sa and pK value analysis. Awards: Regents Professor, McMullin Professor of Genetics. Notable Collaborations: Postdoctoral work with Charles Tanford (Duke), Gordon Hammes (Cornell), Tom Creighton, and Alan Barrett (Cambridge).

Felix Jonasمشاهده پروفایل

استادیار

• Biochemistry
• Gene Regulation
• Transcription Factors
• +۴ مورد دیگر

Prof. Dr. Felix Jonas is an Assistant Professor of Biochemistry at the School of Science, Constructor University Bremen, Germany. He leads research on the biochemistry of gene regulation , focusing on molecular mechanisms governing transcription factor function and chromatin dynamics in Saccharomyces cerevisiae . His work integrates CRISPR-Cas9, Next-Generation Sequencing, and computational data analysis. Education: B.Sc. in Molecular Life Sciences (University of Luebeck), M.Sc. in Biology: Cell Biology (ETH Zurich), Ph.D. in Bioengineering (Imperial College London) Work Experience: Postdoc/Senior Postdoc at Weizmann Institute of Science (2017-22), Visiting Student at Weizmann Institute (2015-16), International Program Associate at RIKEN (2011) Teaching: General Biochemistry (CH-100-B), Introduction to Bioinformatics (JTMS-10), Current Topics in Life Sciences (CA-BCCB-801), Advanced Biochemistry II - Molecular Genetics (CO-403-A) His research explores transcription factor target search , histone dynamics , and chromatin structure-function relationships . Recent publications highlight discoveries in nucleosome replacement, protein disorder grammar, and histone acetylation impacts on replication. Articles emphasize interdisciplinary approaches to eukaryotic gene regulation and systems biology. Visit his lab’s PhD recruitment page or watch his Fragile Nucleosome Talk for deeper insights into his work.

Nediljko Budisaمشاهده پروفایل

استاد

• Synthetic Biology
• Xenobiology
• Genetic Code Engineering
• +۷ مورد دیگر

Nediljko Budisa is a Professor and Tier 1 Canada Research Chair in Chemical Synthetic Biology and Xenobiology at the University of Manitoba's Faculty of Science, Department of Chemistry. His research program focuses on expanding the fundamental biochemical capabilities of living systems through genetic code engineering and synthetic biology approaches. Dr. Budisa's research spans multiple cutting-edge areas in synthetic biology, with particular emphasis on genetic code expansion , non-canonical amino acid incorporation , and protein engineering . His laboratory employs both classical biochemical techniques and advanced computational methods to develop orthogonal translation systems, engineer novel enzymes, and create synthetic cells with expanded biochemical repertoires. His work bridges chemistry, biology, and engineering to address fundamental questions about life processes while developing practical applications in biotechnology and medicine. Analysis of Dr. Budisa's publication record reveals a consistent trajectory of innovation in genetic code engineering, with recent work increasingly integrating machine learning approaches for protein design. His research spans from fundamental studies of protein structure-function relationships to applied research in metabolic engineering and antiviral strategies, demonstrating the versatility of synthetic biology approaches. Tier 1 Canada Research Chair in Chemical Synthetic Biology and Xenobiology Dr. Budisa leads an active research program supported by his Canada Research Chair position, with extensive collaborations across Canada and internationally. His work has resulted in numerous patents and commercial applications in biotechnology. He actively participates in the synthetic biology community through initiatives like Prairie iGEM BioExM and has delivered public lectures on methodological challenges in expanded genetic code research. His research is conducted through the Chemical Synthetic Biology and Xenobiology laboratory at the University of Manitoba, where his team explores the social, cultural, educational, ethical and philosophical aspects of synthetic biology alongside technical innovations, reflecting a comprehensive approach to advancing this transformative field.

Nicolas Bordenaveمشاهده پروفایل

دانشیار

• Food Science
• Nutritional Biochemistry
• Starch Research
• +۲ مورد دیگر

Associate Professor Nicolas Bordenave is a cross-appointed member at the School of Nutrition Sciences, University of Ottawa, focusing on molecular interactions between macronutrients and phytonutrients in food systems. His research explores how these interactions affect glycemic response and phenolic bioavailability in cereal, fruit, and vegetable-based systems. Education: Ph.D. in Food Science (specific institution not mentioned in text) Prior Roles: Research positions at PepsiCo (Chicago, UK) and postdoctoral training at Purdue University's Whistler Center Professional Involvement: Board member of Feeding Tomorrow (IFT Foundation), contributor to Radio Canada's Moteur de recherche program His research spans starch/phenolic interactions , nutritional functionality , and biodegradable packaging materials , with applications in metabolic health and food formulation . Recent publications highlight trends in beta-glucan viscosity , starch digestibility , and phytonutrient delivery . Scientific contributions include methodological advancements in glycemic response assessment and chitosan-based packaging . Key collaborations include work with researchers at Purdue, PepsiCo, and industry partners. His lab investigates macronutrient-phytonutrient interactions , nutritional biochemistry , and functional food design . Current projects align with improving metabolic health through optimized food structures.

Ping Zhouمشاهده پروفایل

دانشیار

• Neurovascular Biology
• Alzheimer's Disease
• Cerebral Amyloid Angiopathy
• +۵ مورد دیگر

Ping Zhou is an Associate Professor of Research in Neuroscience at the Brain and Mind Research Institute, Weill Cornell Medical College, where he has been conducting groundbreaking research since 2013. His work focuses on understanding the molecular mechanisms underlying neurovascular dysfunction in Alzheimer's disease and other neurodegenerative conditions. Dr. Zhou received his Ph.D. from the University of Illinois at Urbana-Champaign in 1991 and completed his undergraduate studies at Nanjing University in China in 1982. His educational background provided the foundation for his extensive research career in neuroscience and neurovascular biology. Dr. Zhou's research interests center on neurovascular coupling, cerebral amyloid angiopathy, and mitochondrial mechanisms of neuroprotection. His laboratory investigates how ApoE4 contributes to neurovascular dysfunction, the role of border-associated macrophages in white matter injury, and the neuroprotective functions of prohibitin through S-nitrosylation. His work bridges basic molecular mechanisms with translational applications for treating neurodegenerative diseases. Analysis of Dr. Zhou's recent publications reveals a strong focus on the intersection of neuroinflammation and neurovascular dysfunction in Alzheimer's disease. His work increasingly incorporates single-cell and epigenetic approaches while maintaining a strong emphasis on mitochondrial function and oxidative stress pathways. The research shows a clear progression from basic mechanisms of neurovascular coupling to more complex investigations of macrophage interactions and genetic risk factors like ApoE4. Dr. Zhou currently serves as Principal Investigator on the NINDS-funded project "Role of prohibitin nitrosylation in its neuroprotective functions" (2022-2027) and as Co-Investigator on two additional NINDS grants: "ApoE4, neurovascular injury and cognitive impairment" (2022-2027) and "Dietary sodium, neurovascular dysfunction and cerebrovascular risk" (2021-2026). These projects reflect his continued focus on molecular mechanisms of neuroprotection and vascular contributions to cognitive impairment. While the available information doesn't specify his laboratory structure, Dr. Zhou's extensive publication record spanning over two decades suggests leadership of a productive research team focused on neurovascular biology and neurodegeneration mechanisms.

Shawn Chenمشاهده پروفایل

استادیار

• Deep learning
• Computational biology
• Bioinformatics
• +۳ مورد دیگر

Shawn Chen is an Assistant Professor of Computer Science at Hamilton College, focusing on deep learning and its applications in computational biology and bioinformatics. His research emphasizes protein structure prediction, determination, and function prediction. Educational Background: Ph.D., University of Missouri-Columbia M.A., University of Missouri-Columbia B.S., Anhui Polytechnic University, Wuhu, China Shawn's work bridges deep learning with computational biology , particularly in enhancing protein structure prediction through cryo-EM map enhancement, graph neural networks, and genome-scale modeling tools. His publications reflect expertise in AI-driven structural validation, protein complex quality assessment, and dataset creation for computational methods. Recent trends in his research include leveraging long-tail gene ontology terms for protein function prediction, integrating equivariant graph neural networks for 3D structure refinement, and advancing template-free prediction via deep ranking algorithms. He is accessible via email at schen3@hamilton.edu and located in Taylor Science Center, Room 2016.

Emil Marklundمشاهده پروفایل

استادیار

• Molecular Biology
• Biochemistry
• Biophysics
• +۳ مورد دیگر

Emil Marklund is an Assistant Professor at Stockholm University's Department of Biochemistry and Biophysics, leading his research group in exploring molecular recognition mechanisms and sequence-structure-function relationships in biological macromolecules. His lab combines high-throughput biophysical measurements with computational modeling to achieve quantitative understanding of molecular interactions. Research focuses include: High-throughput analysis of molecular binding specificity Computational modeling of macromolecular interactions Structural biology and biophysics of protein-DNA/RNA systems In 2025, the lab received a prestigious Future Research Leader grant (SEK 15 million over five years) from the Swedish Foundation for Strategic Research, which will support both research and leadership development. Contact: emil.marklund@dbb.su.se

Mark F Reynoldsمشاهده پروفایل

دانشیار

• Inorganic Biochemistry
• Heme-Based Gas Sensing Proteins
• Bioremediation
• +۳ مورد دیگر

Mark F Reynolds is an Associate Professor at the Department of Chemistry and Biochemistry, Saint Joseph’s University. He earned a BA in Chemistry from Grinnell College (1993) and a PhD in Inorganic Chemistry from the University of Wisconsin-Madison (1999), followed by postdoctoral work at the University of Minnesota. His research focuses on heme-based gas sensing proteins that regulate biological processes like blood pressure and nitrogen fixation. He pioneered studies on the oxygen-sensing FixL protein in alfalfa and soybean agriculture and discovered the heme-responsive ion channel in human Slo1 BK channels. Collaborations with Dr. Toshi Hoshi’s lab at the University of Pennsylvania advanced understanding of heme signaling. Recent publications highlight bioremediation of industrial dyes via heme protein catalysis (2024), conformational dynamics in FixL oxygen sensing (2024), and structural analysis of Mn(II) enzyme active sites (2005). Scientific awards include the 2022 ACS Excellence in College Teaching Award . He has directed the Office of Fellowships at Saint Joseph’s University, mentoring students to secure Fulbright , Goldwater , and NSF fellowships. His outreach includes urban nutrition education projects and media appearances on NPR and in Science Daily .

• Molecular Biology
• CRISPR-Cas Systems
• Microbial Genetics
• +۳ مورد دیگر

Professor Lennart Randau is a leading researcher in the field of Genetics at Philipps University of Marburg, affiliated with the Faculty of Biology. His work is conducted in conjunction with the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, where he investigates molecular mechanisms underlying CRISPR-Cas systems and related biotechnological applications. Research focus on CRISPR-Cas evolution and inhibition mechanisms Investigates structural and functional diversity of prokaryotic defense systems Active in developing genome engineering tools from microbial systems His recent publications highlight CRISPR-Cas transitions from natural immunity to synthetic biology applications, with particular emphasis on anti-CRISPR proteins and transposon-associated gene integration mechanisms. Professor Randau's laboratory employs interdisciplinary approaches combining molecular biology, biochemistry, structural biology, and genomics to unravel the complexities of microbial genetic defense systems and their potential applications in biotechnology.

• Endocytosis
• Neurons
• Membrane Trafficking
• +۲ مورد دیگر

Peter McPherson, PhD, is a Professor in the Department of Neurology and Neurosurgery at McGill University 's Faculty of Medicine and Health Sciences . He is based at the Montreal Neurological Institute (MNI), where his laboratory is part of the MNI’s Neurodegenerative Disease Research Group. University: McGill University School: Faculty of Medicine and Health Sciences Department: Department of Neurology and Neurosurgery Lab Affiliation: Brain Tumour Research Centre, Montreal Neurological Institute Research Focus : Dr. McPherson’s lab investigates molecular mechanisms regulating endosomal membrane trafficking and its role in neurological disorders. Key areas include: Clathrin-coated pit/vesicle dynamics in neurons Links between trafficking defects and neurodevelopmental/neurodegenerative diseases (e.g., Parkinson’s, ALS, ARSACS, glioblastoma) Antibody validation via YCharOS initiative with industry partners Structural and functional characterization of trafficking proteins Recent Trends : Publications emphasize antibody validation protocols (2024-2025), α-synuclein pathology in Parkinson’s, and DENND5A/RAB35 mutations in epileptic encephalopathy. Collaborative work spans lysosomal positioning , autophagy regulation , and C9orf72/SMCR8 complexes in inflammation. Labs & Teams : The lab operates at the Montreal Neurological Institute in the Brain Tumour Research Centre , collaborating with 14 antibody manufacturers and knockout cell line providers through YCharOS. The team uses biochemical, molecular, structural, and cellular approaches to study endo/lysosomal pathways.

Sunil Thomasمشاهده پروفایل

استاد پژوهش

• Translational Research
• Vaccine Development
• Immunotherapy
• +۶ مورد دیگر

Sunil Thomas, PhD , is a Research Professor at the Lankenau Institute for Medical Research (LIMR), with a distinguished career in translational science. His work bridges microbiology, immunology, molecular biology, and cell biology to develop diagnostic tools and vaccines for diseases affecting millions globally. He has held academic titles at LIMR since 2012, including Research Assistant Professor, Research Associate Professor, and now Research Professor. Current roles: Research Professor (2022–Present), Editor of Vaccine Design: Methods and Protocols (Springer-Nature), and Visiting Professor at Temple University (2017). Education: BSc in Botany (Kerala University), MSc in Biotechnology (Cochin University of Science and Technology), PhD in Environmental Biotechnology (Cochin University), and Postdoctoral Fellowship at Mount Sinai School of Medicine. Research interests encompass translational studies on immunotherapies for ulcerative colitis and Alzheimer’s disease, focusing on Bin1 monoclonal antibodies. He has pioneered structure-based vaccines for ehrlichiosis, modeled SARS-CoV-2 membrane proteins, and developed diagnostic tools like the ELISA kit for T-cell lipid rafts and Eastern Blotting for post-translational modifications. His lab investigates antibody uptake mechanisms and gut-brain axis interactions using animal models. Recent publications highlight his work on viral protein structure (Camp Hill, Borealpox, Oropouche), microbiome analysis in ICUs, diet-immunotherapy interactions, and advancements in AI-driven vaccine design. He has also contributed to understanding SARS-CoV-2 pathogenesis, monoclonal antibody therapies, and microbiome-host health connections. Patents include methods for disease treatment, Ehrlichia diagnostics, biosimulator technology, heat shock protein peptides, and vaccines against ehrlichiosis. Commercialized products like the IDO1 monoclonal antibody are now diagnostic probes in cancer research.

Klaus B. Tenbergeمشاهده پروفایل

استاد

• Molecular Cytology
• Plant-Pathogen Interactions
• Electron Microscopy
• +۳ مورد دیگر

PD Dr. Klaus B. Tenberge is a Professor in the Department of Botany at the University of Münster, Germany. His research focuses on molecular cytology of plant-pathogen interactions and cell wall biology , with a particular emphasis on Claviceps purpurea infections in rye and Botrytis cinerea interactions with tomato/bean plants. He has supervised numerous doctoral and state examination theses since 1992 and serves on the Münster State Examination Office for biology teaching positions. Education: Biology and Mathematics at University of Münster (First State Examination, Doctorate, Habilitation in Botany) Contact: Schlossplatz 7, Münster | tenberg@uni-muenster.de His research projects analyze host-pathogen dynamics using light/electron microscopy , immunogold labeling , and in situ hybridization , targeting mechanisms like cell wall degradation , active oxygen species , and scavenging enzymes . Key collaborations include work on Claviceps and Botrytis systems with DFG and EU funding. He contributes to scientific societies (German Botanical Society, German Society for Electron Microscopy) and peer-review for journals such as Molecular Plant Pathology and New Phytologist . Recent teaching includes modules on field biology , plant biodiversity , and electron microscopy .

Peter Cloteمشاهده پروفایل

استاد

• Computational Biology
• Bioinformatics
• Synthetic Biology
• +۶ مورد دیگر

Peter Clote is a Professor of Biology at Boston College, with research focusing on computational biology , bioinformatics , synthetic biology , and RNA molecular design . His work integrates RNA thermodynamics , folding kinetics , and machine learning to develop algorithms for RNA structure prediction and functional design. He holds a Sc.B. from MIT , a Ph.D. from Duke University , and a Doctorat d'Etat from University of Paris VII . Research Interests : Computational biology, synthetic biology, RNA folding algorithms, structural motifs, molecular evolution, and proteomics. Awards : Guggenheim Fellow in Applied Math (2013-2014). Collaborations : Extensive partnerships with institutions including MIT, University of Paris-Sud, CSIC Madrid, and European Bioinformatics Institute. Publication Trends : His work emphasizes RNA structural networks , kinetic modeling , thermodynamic algorithms , and synthetic RNA design , contributing to understanding RNA's role in gene regulation and synthetic biology applications.

Lynn Kamerlinمشاهده پروفایل

استاد

• Computational Biophysics
• Molecular Evolution
• Enzyme Engineering
• +۱۲ مورد دیگر

Lynn Kamerlin is a Professor at the Georgia Institute of Technology and co-leads the Kamerlin Laboratory, which operates across Georgia Tech and Lund University. Her work integrates computational chemistry and biophysics to address fundamental questions in enzyme evolution, catalysis, and protein design. Education MNatSc in Chemistry, University of Birmingham (UK) PhD in Chemistry, University of Birmingham (UK) Her research spans computational biophysics , focusing on mechanistic biochemistry , protein evolution , and enzyme engineering . Key methodologies include machine learning , molecular dynamics simulations , EVB/QM/MM modeling , and natural language models for protein structure prediction. Recent publications highlight trends in AI-driven enzyme design , conformational dynamics , and mechanistic studies of phosphoryl transfer reactions . Tools like WatCon and Q-RepEx demonstrate her commitment to method development in computational biology. Scientific Awards Georgia Research Alliance Eminent Scholar (2022-Present) Wallenberg Scholar (2020-2024) ERC Starting Grant (2012-2017) Wallenberg Academy Fellowship (2014-2019, prolonged 2019-2024) Young Academy of Europe Chair (2014-2015) Fellow of the Royal Society of Chemistry (2017) Her lab collaborates with experimental groups worldwide, leveraging enhanced sampling techniques and structural bioinformatics to engineer enzymes with tailored properties. Grants from the Swedish Research Council and European Research Council underpin her research on enzyme evolution and catalytic mechanisms. Current projects include computational design of thermostable enzymes , allosteric modulators for biomedical targets, and modular protein scaffolds . The lab also investigates non-canonical amino acid incorporation and FAIR data principles in biomolecular simulations.