Mark F Reynolds

Mark F Reynolds is an Associate Professor at the Department of Chemistry and Biochemistry, Saint Joseph’s University. He earned a BA in Chemistry from Grinnell College (1993) and a PhD in Inorganic Chemistry from the University of Wisconsin-Madison (1999), followed by postdoctoral work at the University of Minnesota.

His research focuses on heme-based gas sensing proteins that regulate biological processes like blood pressure and nitrogen fixation. He pioneered studies on the oxygen-sensing FixL protein in alfalfa and soybean agriculture and discovered the heme-responsive ion channel in human Slo1 BK channels. Collaborations with Dr. Toshi Hoshi’s lab at the University of Pennsylvania advanced understanding of heme signaling.

Recent publications highlight

• bioremediation of industrial dyes via heme protein catalysis (2024),
• conformational dynamics in FixL oxygen sensing (2024),
• and structural analysis of Mn(II) enzyme active sites (2005).

Scientific awards include the 2022 ACS Excellence in College Teaching Award. He has directed the Office of Fellowships at Saint Joseph’s University, mentoring students to secure Fulbright, Goldwater, and NSF fellowships. His outreach includes urban nutrition education projects and media appearances on NPR and in Science Daily.