Lynn Kamerlin

Lynn Kamerlin is a Professor at the Georgia Institute of Technology and co-leads the Kamerlin Laboratory, which operates across Georgia Tech and Lund University. Her work integrates computational chemistry and biophysics to address fundamental questions in enzyme evolution, catalysis, and protein design.

• Education
  • MNatSc in Chemistry, University of Birmingham (UK)
  • PhD in Chemistry, University of Birmingham (UK)

Her research spans computational biophysics, focusing on mechanistic biochemistry, protein evolution, and enzyme engineering. Key methodologies include machine learning, molecular dynamics simulations, EVB/QM/MM modeling, and natural language models for protein structure prediction.

Recent publications highlight trends in AI-driven enzyme design, conformational dynamics, and mechanistic studies of phosphoryl transfer reactions. Tools like WatCon and Q-RepEx demonstrate her commitment to method development in computational biology.

• Scientific Awards
  • Georgia Research Alliance Eminent Scholar (2022-Present)
  • Wallenberg Scholar (2020-2024)
  • ERC Starting Grant (2012-2017)
  • Wallenberg Academy Fellowship (2014-2019, prolonged 2019-2024)
  • Young Academy of Europe Chair (2014-2015)
  • Fellow of the Royal Society of Chemistry (2017)

Her lab collaborates with experimental groups worldwide, leveraging enhanced sampling techniques and structural bioinformatics to engineer enzymes with tailored properties. Grants from the Swedish Research Council and European Research Council underpin her research on enzyme evolution and catalytic mechanisms.

Current projects include computational design of thermostable enzymes, allosteric modulators for biomedical targets, and modular protein scaffolds. The lab also investigates non-canonical amino acid incorporation and FAIR data principles in biomolecular simulations.