جست‌وجوی استاد و پژوهشگر

• Plant Pathology
• Microbial Genetics
• Plant-Microbe Interactions
• +۳ مورد دیگر

Dr. Jessica Erickson is a Junior Group Leader at the University of Tübingen’s Center for Integrative Biological Signaling Studies (ZMBP), within the Department of General Genetics. Her research focuses on bacterial pathogens’ manipulation of plant apoplast environments, particularly through secreted proteins like those from Xanthomonas . She leads the Bacterial Apoplast Modulators Lab, studying virulence mechanisms and plant immune responses. Academically, she holds a Ph.D. from Martin Luther University Halle-Wittenberg and postdoctoral experience at the Leibniz Institute of Plant Biochemistry. Her career includes independent project leadership funded by the DFG’s Walter Benjamin Program. Current projects leverage molecular biology, biochemistry, and computational approaches, using Arabidopsis and Nicotiana benthamiana as model systems. Research interests include effector protein function, microtubule dynamics, and stromule formation in plant cells. Her lab collaborates broadly, with publications in PLOS Pathogens , Plant Cell Physiol , and Plant Physiology . Open positions exist for bachelor/master’s theses, emphasizing plant-bacteria interaction studies. Key grants include DFG support for her independent research and infrastructure for multiplex gene editing. The lab’s future work aims to dissect how bacterial proteins reprogram plant apoplast environments to enable disease progression.

Narcis Fernandez Fuentesمشاهده پروفایل

دانشیار

• Bioinformatics
• Structural Bioinformatics
• Protein Design
• +۵ مورد دیگر

Narcis Fernandez-Fuentes is an Associate Professor at the Institute of Biological, Environmental & Rural Sciences (IBERS) at Aberystwyth University. He was previously a Lecturer at the Leeds Institute of Molecular Medicine (2007-2011) and a Research Associate at Albert Einstein College of Medicine (2004-2007). He holds an M.Sc. in Biotechnology and a Ph.D. in Computational Biology from Universitat Autonoma de Barcelona. His work spans Bioinformatics, Structural Bioinformatics, and Plant Bioinformatics, focusing on protein structure prediction, biomolecular interactions, and computational approaches to plant breeding. Protein design and structure-to-function relationships Peptide-based modulation of protein interactions Genomic analysis of abiotic stress responses in plants SNPs modeling and functional impact assessment Recent articles highlight expertise in computational peptide design for SARS-CoV-2, ulvan lyase characterization, and structural modeling of inflammasomes and protein families. His grants include projects funded by the Welsh Government, BBSRC, and Covestro. Marie Curie Training Fellowship EMBO and FEBS Short Term Fellowships Boehringer Ingelheim Fonds Fellowship

B. Mark Eversمشاهده پروفایل

استاد

• Gastrointestinal Surgery
• Oncology
• Cancer Biology
• +۳ مورد دیگر

B. Mark Evers is a Professor of Surgery at the University of Kentucky , serving as the Director of the Markey Cancer Center and Mark McDowell Cancer Foundation Chair. He specializes in gastrointestinal surgery and oncology, with a focus on cancer biology and metabolic disorders. Dr. Evers holds the prestigious Fellow of the American College of Surgeons (FACS) distinction. Education: MD from the University of Tennessee, Memphis (summa cum laude). Completed residency at the University of Louisville and a fellowship in surgical research at the University of Texas Medical Branch. Research: Dr. Evers' work spans tumor metabolism, intestinal cell biology, and the role of neurotensin in cancer progression. Key areas include glycogen-driven lung adenocarcinoma initiation, neurotensin's impact on atherosclerosis, and radiosensitization strategies for pancreatic neuroendocrine tumors. His studies also address geographic disparities in cancer outcomes, particularly in Appalachian Kentucky. Leadership Roles: Physician-In-Chief, Oncology Service Director, Markey Cancer Center Member of the MD/PhD Program Internal Advisory Committee Key Contributions: Over 160 peer-reviewed publications, including high-impact studies on tumor microenvironment modulation and metabolic reprogramming in cancer therapy. Active in translational research to bridge molecular insights with clinical practice.

• Medicinal Chemistry
• Chemical Biology
• Drug Discovery
• +۷ مورد دیگر

Ben Morrow is a Senior Research Fellow in Medicinal Chemistry at Monash University, affiliated with the Faculty of Pharmacy and Pharmaceutical Sciences. His research focuses on the development of chemical probes and therapeutic agents targeting cancer and oxidative stress pathways. His research interests include Medicinal Chemistry , Chemical Biology , Redox Biology , Drug Discovery , and Epigenetics . He develops innovative tools such as mitochondria-targeted redox probes and inhibitors of protein-protein interactions, particularly in cancer-related targets like KAT6A/B and WDR5. The recent publication trends show a strong emphasis on targeted cancer therapies, bioactivation studies of drug candidates, and advanced imaging techniques for monitoring oxidative stress. His work bridges fundamental chemical design with biological application, contributing significantly to both chemical probe development and preclinical therapeutic discovery. While no specific scientific awards are listed in the provided text, his work has been referenced in at least 15 patents and picked up by multiple news outlets, indicating translational impact. Dr. Morrow collaborates extensively with large interdisciplinary teams, as evidenced by co-authorship on high-author-count papers, though specific grants or student supervision details are not mentioned. His work contributes to UN Sustainable Development Goals related to good health and well-being. He is involved in collaborative research networks focused on drug discovery and chemical biology, working with experts in structural dynamics, toxicology, and cancer biology. His research outputs are highly cited, particularly his 2012 paper in the Journal of the American Chemical Society, which has over 120 citations.

Panagiotis Xynogalosمشاهده پروفایل

پژوهشگر

• Cardiac Electrophysiology
• Ion Channels
• Cardiac Implantable Electronic Devices (CIEDs)
• +۳ مورد دیگر

Panagiotis Xynogalos is a Senior Physician and Medical Director at Heidelberg University Hospital (UKHD), affiliated with the Department of Cardiology, Angiology, and Pulmonology. He leads the Pacemaker Surgery unit and the Siebeck II/von Weizsäcker Ward, while also serving as a Research Associate in the Ag Ion Channel Signaling Complexes group. His clinical roles include managing cardiac rhythm implants and invasive electrophysiology procedures. Dr. Xynogalos holds a PhD in molecular cardiology (2015) from Heidelberg University, focusing on Kir2.x potassium channels. His research spans cardiac electrophysiology, ion channel pharmacology, and device-associated complications. He is a member of the Deutsche Gesellschaft für Kardiologie (DGK) and European Society of Cardiology (ESC). Key contributions include studies on verapamil's effects on Kir2.3 channels, radiation impacts on CIEDs, and telemedicine acceptance for arrhythmia patients. His work bridges clinical electrophysiology with molecular mechanisms, emphasizing translational research in arrhythmia management.

Stefan Knappمشاهده پروفایل

استاد

• Pharmaceutical Chemistry
• Cancer Biology
• Epigenetics
• +۳ مورد دیگر

Stefan Knapp is a Professor of Pharmaceutical Chemistry at Goethe University, leading research into small molecules targeting epigenetic mechanisms and cancer cell proliferation. His work emphasizes translational research, open science, and collaboration, exemplified by his role in managing the EUbOPEN consortium, which secured €65.8 million in funding. He focuses on developing therapies through partnerships with industry, prioritizing efficiency and transparency to accelerate drug discovery. Knapp's research interests include kinase inhibitors, molecular glues, and targeted protein degradation, with applications in oncology and neurodegenerative diseases. His achievements include EMBO membership (2018) and pioneering open-science initiatives to share data and reagents rapidly. Knapp's lab employs cutting-edge methods like native Taylor dispersion-MS and fragment-based screening to identify novel therapeutic targets. Collaborative efforts span international networks, reflecting his belief in global teamwork for scientific advancement. Key projects include therapeutic targeting of NPM1c in AML and inhibition of LRRK2 in Parkinson's disease. Grants and funding highlight his success in securing resources for transformative research, while his open-access approach aims to reduce redundant efforts and expedite medical breakthroughs. Knapp's interdisciplinary work bridges academia and industry, focusing on ethical and socially impactful science with direct clinical applications.

Karen Gregoryمشاهده پروفایل

دانشیار

• Allosteric Modulation of G Protein-Coupled Receptors
• Drug Discovery
• Molecular Modeling
• +۳ مورد دیگر

Karen Gregory is an Associate Professor in the Department of Drug Discovery Biology at Monash University. Her research focuses on allosteric modulation of Class C G protein-coupled receptors (GPCRs), particularly targeting neuropsychiatric and metabolic disorders. She leads projects on drug discovery for epilepsy, osteoporosis, and asthma, with expertise in molecular modeling and ligand design. Key collaborations include studies on adenosine A1 receptor modulators for drug-resistant epilepsy and investigations into metabotropic glutamate receptor signaling. Her work contributes to UN Sustainable Development Goals related to health and innovation. Gregory has received recognition such as the NHMRC Overseas Biomedical Research Fellowship (2011-2015) and the NARSAD-Maltz Young Investigator Award (2010). She supervises projects at the Gregory Laboratory and participates in academic committees like the MPGPCR organizing committee. Her recent publications (2024) explore topics like GRM1 mutations, adenosine system roles in epilepsy, and trace amine receptor variants. She holds grants totaling over $2 million for drug discovery initiatives. Labs/Teams: Gregory Laboratory, collaborating with teams in Melbourne Magnetic Resonance Facility and drug discovery alliances.

Jon Robbinsمشاهده پروفایل

استاد

• Neuroscience
• Cellular Neurophysiology
• Ion Channel Regulation
• +۵ مورد دیگر

Dr. Jon Robbins is a Reader in Neuroscience Education and Head of the Department of Neuroscience Education at King's College London, within the Institute of Psychiatry, Psychology & Neuroscience. He leads the Education Lead role for the Division of Neuroscience and is affiliated with the Wolfson Sensory, Pain and Regeneration Centre. His academic career includes a PhD in Cellular Neuroscience from the University of London (1987) and a BSc from University College London (1982). Research interests focus on ion channel regulation by signaling pathways and microbial toxins, employing electrophysiology and microfluorimetry. Key topics include proton-activated ion channels, neuronal-semiconductor interfaces, and lipidated peptides. Collaborations include work with Prof. Julian Naglick (King's College London) and Dr. Richard Killick (King's College London). Publications highlight contributions to fungal toxin mechanisms (e.g., Candidalysin) and ion channel physiology (e.g., KCNQ2 potassium channels). Projects funded include CMOS electrode development for biosensors and studies on astrocyte ion channels. Awards and grants are extensive but not explicitly listed in the provided materials. He advises on grants and serves on editorial boards, including roles with IUPHAR and 'Integrated Pharmacology' textbooks. His lab's work bridges basic neuroscience with translational applications in neurotechnology and disease mechanisms.

Sefer Badayمشاهده پروفایل

استادیار

• Bioinformatics
• Computational Biology
• Molecular Dynamics Simulation
• +۳ مورد دیگر

Sefer Baday is an Assistant Professor at Istanbul Technical University's Informatics Institute, Department of Informatics Applications , holding a PhD from the University of Basel (2013). His interdisciplinary research bridges computational biology, structural bioinformatics, and drug discovery. Education: PhD (Computational Biology, University of Basel), MA (Computational Sciences, Koç University), Licence (Chemical Engineering, Bogazici University) Positions: Assistant Professor (2015–present, Istanbul Technical University); Research Assistant (2014–2015, University of Cambridge; 2009–2014, University of Basel) Research Interests: Focus on computational modeling of biological systems, including: Mechanistic studies of ion channels (Ryanodine receptors) Machine learning for molecular docking acceleration Force field optimization for drug interactions Peptide engineering for therapeutic applications Antiviral and anticancer drug development Plant nutrient transport mechanisms Publication Trends : Recent work (2021–2025) emphasizes molecular docking , CHARMM force field , machine learning , and drug repurposing , with applications in cardiovascular disease , cancer , and virology . Earlier studies (2007–2016) focused on protein folding , ammonium transport , and biomaterials . Projects : Leading six funded initiatives, including: GPX4 Ligand Recognition (2025–2027, BAP) Ryanodine Receptor Inhibitors (2020–2023, TUBITAK) Enzalutamide Resistance (2017–2020, TUBITAK) Alzheimer's Enzyme Inhibitors (2017–2020, BAP) Stapled Peptide Linkers (2016–2017, TUBITAK) Collaborations span institutions like University of Cambridge, University of Basel, and Koç University, with co-authors in Turkey, Switzerland, and Germany. Methodologies include molecular dynamics simulations , machine learning , and CHARMM force field development. Techniques : Expert in computational approaches to protein structure-function relationships, ligand binding, and nanomaterial design, with applications in drug discovery and regenerative medicine.

Lisa McConlogueمشاهده پروفایل

استاد پژوهشی

• Neurodegeneration
• Protein Misfolding
• Alzheimer's Disease
• +۵ مورد دیگر

Lisa McConlogue is a Research Professor at the University of California, San Francisco, where she leads the McConlogue Laboratory focused on neurodegeneration mechanisms and therapeutic development. Her research investigates protein misfolding disorders including Alzheimer's disease, Parkinson's disease, and Lewy body dementias, with particular expertise in intrinsically disordered proteins like alpha-synuclein. Dr. McConlogue's education includes a B.A. in Mathematics (1973), M.S. in Medical Physics (1975), and Ph.D. in Medical Physics (1978) from UCLA, followed by postdoctoral training in Somatic Cell Genetics at UCSF (1985). Her primary research examines the pathogenic mechanisms of alpha-synuclein misfolding and identifies therapeutic chaperones that block neurodegeneration. Current work focuses on Hsp70's non-canonical engagement with alpha-synuclein, which shows promise for treating multiple neurodegenerative diseases. She has secured NIH funding as Principal Investigator for projects including 'Small-Molecule Pharmacological Chaperones to Prevent Synuclein Transmission' (2015-2018). McConlogue's publication record demonstrates consistent focus on protein misfolding mechanisms, therapeutic targeting, and disease models across neurodegenerative conditions. Her recent work emphasizes structural biology approaches to alpha-synuclein modulation and chaperone-based interventions.

Andrew Gewirtzمشاهده پروفایل

استاد

• Innate Immunity
• Microbiome
• Intestinal Inflammation
• +۲ مورد دیگر

Andrew Gewirtz is a Regents’ Professor and Distinguished University Professor at Georgia State University's Institute for Biomedical Sciences, where he conducts pioneering research on innate immunity, the gut microbiome, intestinal inflammation, and metabolic disorders including obesity and diabetes. His work centers on understanding how pro-inflammatory pathways protect against microbes and become dysregulated in disease states, with primary focus on the intestinal epithelium as a critical host-microbe interface. Education: Ph.D. in Biochemistry, Boston University School of Medicine, 1996 Dr. Gewirtz's research investigates how the intestinal epithelium maintains homeostasis through antimicrobial production and immune cell recruitment, and how disruptions lead to chronic inflammation. His laboratory has established fundamental connections between Toll-like receptor signaling (particularly TLR5), gut microbiome composition, and metabolic syndrome. Key discoveries include demonstrating that TLR5 deficiency causes dysbiosis leading to obesity and colitis, and identifying flagellin as a critical microbial factor driving inflammatory responses. His publication record (2005-2012) reveals consistent focus on host-microbe interactions, with dominant themes in TLR5 signaling, Proteobacteria-driven inflammation, and the microbiome's role in metabolic disease. The work predominantly employs mouse models to dissect molecular mechanisms linking innate immunity to gut barrier function and systemic inflammation. Scientific Awards: Regents’ Professor Distinguished University Professor Dr. Gewirtz maintains an active research program with extensive collaborations across immunology and microbiome research. His laboratory at Georgia State's Petit Science Center generates foundational insights into inflammatory pathways, with implications for treating inflammatory bowel disease, obesity, and diabetes. While specific grant details aren't provided, his high-impact publications indicate substantial research support. His laboratory focuses on experimental models of gut inflammation, microbial community analysis, and molecular dissection of epithelial-immune interactions, directly contributing to translational applications in inflammatory and metabolic disorders.

• Cancer Biology
• Immunology
• Molecular Systems Biology
• +۲ مورد دیگر

Stein F. is an active researcher at the German Cancer Research Center (DKFZ), contributing to oncology-focused studies with multi-disciplinary collaborations. Research spans cancer biology, molecular systems, and translational medicine. Research Focus: Work encompasses RNA-binding protein dynamics, intracellular signaling networks, and immuno-oncology. Recent studies explore: Cardio-oncology care models integrating cardiology and cancer management Epigenetic modulation of tumor immunogenicity High-content imaging platforms for cellular signaling analysis Publications: Articles demonstrate consistent focus on molecular oncology mechanisms and clinical translation, with recent emphasis on immunogenic neoepitopes and signaling pathway profiling.

Dakshina (Moody) Jandhyalaمشاهده پروفایل

استادیار

• Bacterial Pathogenesis
• Toxin-Mediated Diseases
• Cell Death Signaling
• +۴ مورد دیگر

Dakshina Jandhyala is a Research Assistant Professor at the University of Houston College of Pharmacy's Department of Pharmacological and Pharmaceutical Sciences. She directs the Core Research Laboratories & Facilities, focusing on bacterial toxin mechanisms and inflammatory signaling. Ph.D., Molecular Biology, University of Houston B.S., Biology, University of Texas Her research investigates how bacterial and plant toxins damage ribosomes to trigger cell death and inflammation, while exploring gut microbiota interactions and probiotic modulation of intestinal immunity. Recent publications analyze ZAK kinase's role in toxin signaling, 3D renal models for Stx2 toxicity, and ER stress responses to Subtilase toxin. 2013 Tufts Collaborates! Grant 2012 Charlton Research Grant 2011 NIH/Tufts CTSI Grant As a journal reviewer for 8+ publications, she contributes to peer review in microbiology and pharmacology fields.

• Cellular Neuroscience
• Electrophysiology
• Ion Channels
• +۳ مورد دیگر

James Kenyon is a Professor and Director of the Institute for Neuroscience at the University of Nevada, Reno. He can be contacted at jlkenyon@med.unr.edu and is affiliated with the Institute for Neuroscience in Reno, Nevada. His research focuses on ion channels , calcium signaling , and neuronal excitability , particularly in smooth muscle and gastrointestinal systems. Studies include the role of mitochondria in calcium regulation, temperature effects on neuronal calcium buffering, and phosphorylation mechanisms modulating potassium and chloride channels. Analysis of his 15 most recent articles reveals expertise in gastrointestinal physiology , neurophysiology , and computational modeling . Key themes include calcium-activated chloride channels , Kv channel regulation , and smooth muscle contractility in health and disease models like colitis.

• Cardiology
• Pharmacology
• Neurophysiology
• +۳ مورد دیگر

Dr. Robert Harvey is a Professor and Chair of Pharmacology at the University of Nevada, Reno School of Medicine . His research focuses on understanding the interplay between the autonomic nervous system and cardiac function, particularly how sympathetic and parasympathetic stimulation influence arrhythmias and sudden cardiac death. He has extensively studied cardiac myocyte signaling mechanisms , neurotransmitter effects , and cAMP compartmentation using experimental and computational approaches. Education : B.S. in Pharmacy from Drake University, Ph.D. in Pharmacology from Northwestern University Dr. Harvey's research explores autonomic regulation of cardiac activity and has contributed to understanding neurotransmitter signaling in heart disease. His work spans disciplines including cardiology , neurophysiology , and cell biology , with recent studies analyzing mitochondrial signaling , interstitial cell function , and ion channel dynamics . Recent publication trends show emphasis on cardiac arrhythmias , autonomic nervous system , calcium signaling , and epigenetic factors in cardiovascular disease. His collaborative work involves institutions across the United States and Europe, with studies in mouse models , human physiology , and computational modeling .