Karen Gregory

Karen Gregory is an Associate Professor in the Department of Drug Discovery Biology at Monash University. Her research focuses on allosteric modulation of Class C G protein-coupled receptors (GPCRs), particularly targeting neuropsychiatric and metabolic disorders. She leads projects on drug discovery for epilepsy, osteoporosis, and asthma, with expertise in molecular modeling and ligand design.

Key collaborations include studies on adenosine A1 receptor modulators for drug-resistant epilepsy and investigations into metabotropic glutamate receptor signaling. Her work contributes to UN Sustainable Development Goals related to health and innovation.

Gregory has received recognition such as the NHMRC Overseas Biomedical Research Fellowship (2011-2015) and the NARSAD-Maltz Young Investigator Award (2010). She supervises projects at the Gregory Laboratory and participates in academic committees like the MPGPCR organizing committee.

Her recent publications (2024) explore topics like GRM1 mutations, adenosine system roles in epilepsy, and trace amine receptor variants. She holds grants totaling over $2 million for drug discovery initiatives.

Labs/Teams: Gregory Laboratory, collaborating with teams in Melbourne Magnetic Resonance Facility and drug discovery alliances.