جست‌وجوی استاد و پژوهشگر

• Bioinformatics
• Genomics
• Cancer Research
• +۵ مورد دیگر

Leila Taher is a researcher at the Institute of Biomedical Informatics, TU Graz. Her work focuses on integrating computational methods with genomic data to study cancer biology, epigenetic regulation, and comparative oncology. She has developed tools like T3E and DNA-DDA for analyzing transposable elements and 3D chromatin structure. Her research spans canine and feline cancer models, immune mechanisms, and functional genomics. Key projects include designing targeted NGS panels for canine lymphoma and exploring synergistic drug combinations for B-cell lymphoma. Her interdisciplinary approach bridges bioinformatics, veterinary medicine, and human health. Education and affiliations are not explicitly detailed in the text, but her long-term contributions to genomics (publications span 2003–2024) suggest advanced academic training. Collaborations involve molecular biology, computational biology, and clinical oncology teams. She leads research in areas such as chromatin architecture prediction, enhancer function, and immune cell regulation. Her lab's tools have been applied to study autoimmune diseases, developmental biology, and translational medicine. Research themes include: (1) Developing algorithms for genomic analysis, (2) Investigating epigenetic mechanisms in cancer, (3) Translating canine models to human oncology, and (4) Exploring gene regulatory networks in development. Recent work emphasizes reproducibility in NGS pipelines and the role of repetitive elements in functional genomics.

• RNA Folding
• Computational Biology
• Bioinformatics
• +۳ مورد دیگر

Stefan Badelt holds a PhD and Magister degree in Theoretical Chemistry, currently active within the Faculty of Chemistry at an Austrian institution (likely University of Vienna based on academic conventions). His research spans computational RNA biology, bioinformatics, and molecular engineering with continuous publication output from 2011 through projected 2025 activities. RNA Folding (100%) Protein Secondary Structure (67%) Transcription Processes (45%) Circular RNA Mechanics Alu Element Biology His research focuses on cotranscriptional RNA folding dynamics, developing computational tools like DrForna for visualization and DrTransformer for heuristic folding prediction. Recent work critically examines deep learning limitations in RNA structure prediction while advancing nearest-neighbor energy models. His fingerprint reveals strong specialization in RNA polymerase II dynamics and non-pseudoknotted structural systems. Publication trends show consistent output in high-impact bioinformatics journals, with 2022-2023 featuring significant algorithmic contributions. His work bridges computational methods with experimental validation, particularly in RNA folding pathways and DNA strand-displacement systems. While no specific awards are documented, his publications demonstrate substantial scholarly impact with multiple papers exceeding 10 Mendeley readers and significant citation metrics. Badelt actively mentors students through collaborative projects, evidenced by co-authored publications with Laurenz Miksch and others. His research receives support through computational biology grants enabling development of tools like the commit-and-delay model for RNA dynamics. Future work includes domain-level design of cotranscriptional folding pathways presented at upcoming 2024-2025 conferences. He operates within the Theoretical Chemistry research ecosystem, collaborating closely with Ivo Hofacker's group on RNA bioinformatics. Current activities focus on exact coarse-grained dynamics modeling and pseudoknot-free pathway design, positioning his lab at the intersection of computational biology and molecular engineering.

Andrea Tanzerمشاهده پروفایل

پژوهشگر

• RNA Biology
• Transcriptomics
• Non-Coding RNA
• +۴ مورد دیگر

Andrea Tanzer is a researcher at the Max Perutz Labs, Department of Biochemistry and Cell Biology. Her work focuses on RNA biology, particularly RNA structure and function, non-coding RNA, and bioinformatics tools for genomic analysis. She leads the RNALands project (2015–2019), developing methods for RNA folding landscape analysis. Her research contributes to understanding RNA editing mechanisms, epigenetic regulation, and host-pathogen interactions. Key research interests include RNA structure prediction, transcriptome-wide analyses, and the role of RNA modifications in gene regulation. Tanzer has presented on topics such as RNA bioinformatics, structureomics, and G-quadruplexes in RNA. Her work bridges computational methods and experimental biology, with applications in both fundamental science and biomedical diagnostics. Notable contributions include the RNAxplorer tool for RNA structure sampling and collaborations on the GENCODE project. Media highlights include coverage of her work on mouse genome applications for human diagnostics.

Martin Pichlerمشاهده پروفایل

استاد

• Non-Coding RNA Biology
• Cancer Biology
• Colorectal Cancer
• +۹ مورد دیگر

Martin Pichler is a Full Professor for Translational Oncology at the Faculty of Medicine, University Augsburg, Germany. He holds academic and leadership roles at the Medical University of Graz, including Associated Professor, Head of the Research Unit for Non-Coding RNA and Genome Editing in Cancer, and Research Managing Director of the Division of Oncology. His research focuses on altered expression of non-coding RNAs in human cancers (colorectal, breast, kidney), exploring mechanisms in metastasis, stem cell formation, and tumor metabolism, alongside clinical outcome research and biomarker development. Current Affiliation: University Augsburg (2023–present) Primary Affiliation: Medical University of Graz Education: Medicine (2000–2006), Medical University of Graz Molecular Biology (2004–2009), University of Graz Research interests integrate molecular mechanisms of non-coding RNAs in cancer progression and personalized biomarker studies. His team develops RNA research tools, bioinformatic methods, and genome-editing techniques. Former academic positions include Assistant Professor (2013–2015) and Research Fellow (2013–2015) at MD Anderson Cancer Center, and postdoctoral/residency roles at Medical University of Graz. Key collaborators and advisees include Katharina Jonas (DK-MCD project) and Felix Prinz, both graduated students.

Michael Thomas Wolfingerمشاهده پروفایل

پژوهشگر

• RNA Structure
• Bioinformatics
• Computational Biology
• +۴ مورد دیگر

Michael Thomas Wolfinger is affiliated with the Faculty of Computer Science and the Research Group Bioinformatics and Computational Biology . His work focuses on RNA structure, bioinformatics, and virology. Notable research includes studies on RNA secondary structures in pathogens like Zika virus, flaviviruses, and mechanisms of RNA stability. Conducts research on viral RNA structures and their interactions with host proteins. Develops computational frameworks for genomic data analysis in viral lineage designation. Recent projects include the Design of synthetic RNase-resistant RNA structures (2022–2025), funded by research grants. His work contributes to UN Sustainable Development Goals related to health and innovation. Key collaborations involve institutions studying tick-borne flaviviruses and Aedes albopictus vectors. He has presented findings at multiple scientific conferences via poster presentations.

Manel Estellerمشاهده پروفایل

استاد

• Human cancer
• Histone modifications
• Neurological disorders
• +۲ مورد دیگر

Manel Esteller is a prominent academic and researcher currently serving as the Director of the Josep Carreras Leukaemia Research Institute (IJC), Chair of Genetics at the School of Medicine, University of Barcelona, and a Research Professor at the Catalan Institution for Research and Advanced Studies (ICREA). His work bridges genetics, epigenetics, and cancer research. Research interests include: Epigenome and epitranscriptome mapping in normal and transformed cells Interactions between epigenetic modifications and non-coding RNAs Development of epigenetic drugs for cancer therapy DNA methylation and its role in human cancer Histone modifications and their implications in disease He has received numerous prestigious awards, including the Narcís Monturiol Medal (2020) and multiple European Research Council grants. His editorial roles include being Editor-in-Chief of Epigenetics and Associate Editor for several high-impact journals. He also directs The Cancer Genome Atlas (TCGA) project for Cancer of Unknown Primary (CUP) at the NCI-NIH.

Annick Harel-Bellanمشاهده پروفایل

استاد پژوهشی

• Cell differentiation and cancer
• Small RNAs
• Cell proliferation
• +۲ مورد دیگر

Annick Harel-Bellan serves as Research Professor at the French Alternative Energies and Atomic Energy Commission (CEA), leading the Laboratory of Epigenetics and Cancer within the Institute of Biology and Technology Saclay and the Unit of Integrative Biology and Molecular Genetics. Her career spans over three decades of research on molecular mechanisms governing cell proliferation and differentiation, with a focus on cancer pathogenesis. Her primary research integrates epigenetics, small RNA biology, and transcriptional regulation to investigate how cellular differentiation pathways are disrupted in cancer. She examines the balance between proliferation and differentiation at molecular levels, particularly through epigenetic modifications and non-coding RNA networks, seeking to elucidate fundamental processes underlying tumor development. Dr. Harel-Bellan has been honored with significant awards including: Fogarty fellowship (1986-1988) Prize from the "Ligue du Val de Marne" (1994) Prize from the "Ligue de l'Essonne" (1999) Prize from the Ligue de Paris (Olga Sain) (2001) Prize Rosen Foundation de la Recherche Médicale (2002) Membership in EMBO Membership in Academia Europaea She has maintained continuous leadership at CNRS/CEA since 1988, progressing from heading Transcriptional Regulations groups to directing the Epigenetics and Cancer Laboratory since 1999, establishing a sustained research program in molecular oncology.

Eduard C. Hurtمشاهده پروفایل

استاد

• Nuclear pore complex
• Nucleocytoplasmic transport
• Ribosome biogenesis
• +۶ مورد دیگر

Eduard C. Hurt is a Full Professor (C4) at Heidelberg University's Faculty of Biosciences, Department of Biochemistry, where he has served since 1995. He directed the Heidelberg University Biochemistry Center (BZH) from 2003–2005. Previously, he was a Group Leader at EMBL Heidelberg (1987–1994) and a postdoc at the University of Basel. His PhD was completed at the University of Regensburg. Hurt's research focuses on fundamental cellular mechanisms including: Nuclear pore complex architecture and nucleocytoplasmic transport Transcription-coupled mRNA export and ribosome biogenesis Chromatin organization, sumoylation, and ubiquitination pathways Nuclear envelope dynamics and membrane biogenesis Analysis of his 15 most recent publications reveals strong emphasis on structural biology of nuclear transport complexes, mechanistic studies of ribosome assembly/export, and mRNA quality control at nuclear pores. His work integrates yeast genetics, biochemistry, and advanced microscopy. Awards & Honors: Gottfried Wilhelm Leibniz Prize (2001) Feldberg Prize (2007) Elected Member: Leopoldina (2003), Academia Europaea (2007) He leads research groups at BZH focusing on nuclear pore complexes and ribosome biogenesis, collaborating internationally on structural biology projects. His lab utilizes biochemical reconstitution, CRISPR-based genomics, and cryo-EM to study macromolecular assemblies.

Ann Dalyمشاهده پروفایل

استاد

• Pharmacogenomics
• Liver Disease
• Drug-Induced Liver Injury
• +۷ مورد دیگر

Professor Ann Daly is a distinguished researcher and academic at Newcastle University's Faculty of Medical Sciences, where she serves as Professor of Pharmacogenetics within the Translational and Clinical Research Institute. With over 40 years of academic experience at Newcastle University, she has established herself as a leading expert in pharmacogenetics, particularly focusing on liver disease and drug-induced liver injury. Her research has significant implications for personalized medicine and clinical pharmacology. Professor Daly completed her BA and PhD in Biochemistry at the University of Dublin in 1978 and 1982 respectively. She conducted postdoctoral research at the University of Geneva and Trinity College Dublin before joining Newcastle University, where she progressed from Research Associate to her current Professorial position. She was elected Fellow of the British Pharmacological Society in 2012 and became a Member of Academia Europaea in 2023. Her research interests center on pharmacogenetic studies of novel human genetic polymorphisms, their functional significance, and relationship to drug therapy outcomes, adverse drug reactions, and liver diseases. She coordinates the iDILIC network on genetics of drug-induced liver injury and contributes to several major international projects including TransBioLine, LITMUS, GenomALC, and OPPM. Her work bridges fundamental genetic research with clinical applications to develop personalized treatment approaches. Analysis of her recent publications reveals a strong focus on non-alcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated steatotic liver disease (MASLD), with particular emphasis on genetic and molecular mechanisms, biomarker discovery, and the role of pharmacogenomics in understanding disease progression and treatment response. Her research increasingly incorporates multi-omics approaches, integrating transcriptomic, proteomic, and metabolomic data to understand complex disease pathways. 2019 American Association for the Study of the Liver. Hyman J. Zimmerman Hepatotoxicity State-of-the-Art Lecture 2017 International Society for the Study of Xenobiotics (ISSX), Award for Major Scientific Contributions in the field of Xenobiotics in the European Region 2012 Fellow of the British Pharmacological Society 2009 British Pharmacological Society Australasian Visitor scholarship Professor Daly actively contributes to the scientific community through leadership roles including Chair of the European Society of Pharmacogenomics and Personalised Therapy (2023-2024), Vice-chair of the IUPHAR Pharmacogenetics subcommittee (2018-2023), and membership on the Pharmacovigilance Expert Advisory Group for the Commission on Human Medicines, MHRA. She serves as Senior Editor for the British Journal of Clinical Pharmacology and on the editorial boards of several leading pharmacology journals. Her research is supported by multiple international collaborations and funding sources focused on translating genetic discoveries into clinical practice.

Bozzoni Ireneمشاهده پروفایل

استاد

• Mechanism and regulation of non coding RNA function in mammalian cells
• Role of non coding RNA in gene expression control
• Long non coding RNA
• +۱ مورد دیگر

Irene Bozzoni is a Full Professor of Molecular Biology at the University of Rome, specializing in non-coding RNA research. Her work explores the regulatory mechanisms of non-coding RNA in mammalian cells, their role in gene expression control, and their therapeutic applications in diseases like Duchenne Muscular Dystrophy. Current: Full Professor of Molecular Biology, University of Rome Past: Associate Professor (1986-1994), Staff Scientist (1980-1986), Research Fellow (1978-1980) at CNR, Rome Her research focuses on long non-coding RNAs, microRNA biogenesis, and RNA-based therapies. Publications highlight RNA-gene interactions, muscle differentiation, and molecular circuitries in diseases. Scientific honors include Accademia Nazionale dei Lincei Prizes (2003, 2006), the Sapienza Ricerca Award (2010), and memberships in EMBO and Academia Europaea.

• RNA binding proteins
• Epigenetics
• Root architecture
• +۵ مورد دیگر

Martin Crespi is a CNRS Researcher at the Institute of Plant Sciences Paris-Saclay (IPS2) since 2018 and has led the "Regulatory RNAs in root plasticity" team since 2003. He served as Director of IPS2 (2015-2024), Director of the Plant Genomics Unit (2014-2015), and held leadership roles at CNRS institutions since 1994. Current Position: Researcher, CNRS, IPS2 Leadership: 14-member team (7 permanent) His research focuses on non-coding RNAs, epigenetics, and root development, exploring how riboregulators interact with splicing/chromatin factors to modulate root adaptability. His work bridges plant molecular biology, symbiosis, and environmental stress responses. Recent publications highlight his contributions to understanding RNA-mediated regulation in Arabidopsis and Medicago truncatula, covering topics like alternative splicing, chromatin looping, and miRNAome plasticity. These studies integrate genomics and molecular biology to decode root-soil interactions. Scientific Awards: Prix Dr. Pedro Berdoy (Argentina), National Society of Experimental Biology Award (Argentina) He has supervised 18 PhD students, 43 postdocs, and 14 Masters while leading 61 projects (including 9 EU grants and 7 Marie Curie grants) and participating in over 30 international scientific committees or review panels.

• Molecular Biology
• Biochemistry
• Cell Biology
• +۶ مورد دیگر

Eleonora Candi is a Full Professor in Molecular Biology at the Department of Experimental Medicine, University of Rome Tor Vergata, and Head of the Biochemistry laboratory at IDI-IRCCS hospital in Rome, Italy. Her research focuses on epithelial development, programmed cell death (apoptosis), and the roles of p63, microRNAs, and long non-coding RNAs in skin biology and squamous cell carcinomas. PhD (1995, Rome) in Skin Biochemistry BSc (1991, Rome) in Biology Her expertise spans epithelial differentiation, cancer epigenetics, and transgenic mouse models. She previously held roles as Assistant and Associate Professor at the same university, with fellowships at NIAMS-NIH (USA) and European laboratories. Her editorial roles include Editor-in-Chief of Discover Oncology and membership on multiple journal editorial boards. Alternate of the Shadow Committee for Horizon Europe (2019–2020) Telethon Research Fellow (1999–2001) ECDO Academy Member (2012–present) Dr. Candi has contributed to 158 scientific articles with an H-index of 53, focusing on p63's oncogenic roles and epigenetic regulation in epithelial cancers. She uses biochemical, molecular, and animal model approaches to study cancer cell fate and therapeutic strategies.

Eric Westhofمشاهده پروفایل

استاد

• Nucleic Acid Stereochemistry
• RNA Structural Biophysics
• RNA Bioinformatics
• +۲ مورد دیگر

Professor Eric Westhof at the University of Strasbourg is a leading expert in nucleic acid stereochemistry, RNA structural biophysics, and bioinformatics. He has developed critical computational tools for RNA modeling and crystallographic refinement, including pioneering all-atom tertiary models of catalytic RNAs validated by experimental studies. Positions: Director of CNRS Unit 'Architecture and Reactivity of RNA', Director of CNRS Institute of Molecular and Cellular Biology (IBMC), Vice-President for Research at University of Strasbourg Editorial Roles: Executive Editor of RNA and Nucleic Acids Research His research focuses on RNA sequence-structure evolution and functional dynamics. Key contributions include geometric classifications for RNA base pairs and molecular modeling of ribozymes. Scientific honors include the Jacques MONOD Prize, Structural Biochemistry Chair from Institut Universitaire de France, Fellowships from AAAS and Institute of Physics, and memberships in EMBO, Academia Europaea, and multiple national academies. Grants: Human Frontier Science Program (1997-2000, 2005-2008), European Union projects Leadership: President of RNA Society (2005), President of Société française de Biochimie (2004-2009), EMBO Publications Committee Chair

Cisca Wijmengaمشاهده پروفایل

استاد

• Autoimmune diseases
• Genome of the Netherlands
• Microbiome
• +۸ مورد دیگر

Cisca Wijmenga is a Full Professor of Human Genetics at the University Medical Centre Groningen (UMCG), University of Groningen, since 2007. She served as Rector Magnificus of the University of Groningen from September 2019 to 2023 and held an Adjunct Professorship in Medicine at the University of Oslo (2016-2019). Her research focuses on autoimmune diseases, celiac disease, and integrative genomics. Key affiliations: University of Groningen, UMCG, University of Oslo Research Interests : Dr. Wijmenga's work spans human genetics, genome-wide association studies, and microbiome research, with emphasis on biomarker discovery, non-coding RNA, and biobanking. Her scholarship contributes to understanding genetic factors in autoimmune disorders and population genomics (e.g., Genome of the Netherlands project). Scientific Awards & Honors : 2022 Galjaard Lifetime Achievement Award 2019 European Society of Human Genetics (ESHG) Award 2018 United European Gastroenterology Research Prize 2015 Spinoza Prize (Netherlands' highest scientific award) 2012 ERC Advanced Award (CD-LINK) 2012 Dutch Royal Academy of Arts and Sciences (KNAW) Membership 2005 VICI Award (NWO) 1993 Cum Laude PhD from Leiden University Medical Center As a member of the Academy of Europe (elected 2013), she continues to influence global genetics research.

• RNA Biology
• RNA Synthesis
• RNA Degradation
• +۴ مورد دیگر

David Tollervey is a Professor of RNA Biology and Wellcome Principal Research Fellow at the Wellcome Centre for Cell Biology , University of Edinburgh. He has held this position since 1997 and served as Director of the Centre from 2011 to 2021. His academic journey includes postdoctoral training at UC San Francisco and a PhD in Genetics from the University of Cambridge. Research Interests: Tollervey specializes in RNA biology, focusing on RNA synthesis, degradation, and surveillance mechanisms. His work explores ribosome synthesis, non-coding RNAs in disease, and the interplay between RNA and protein synthesis. Key contributions include defining exosome function and RNA interactome mapping. Education: BSc (Hons) in Microbiology, University of Edinburgh (1973–1977) PhD in Genetics, University of Cambridge (1977–1980) Awards & Honours: Fellow of the Royal Society (2004) President of the RNA Society (2007–2008) Biochemical Society Novartis Medal (2016) Fellow of the Academy of Medical Sciences (2022) Labs & Teams: Leads the RNA Biology group at the Wellcome Centre, focusing on mechanistic and functional studies of RNA processing. Collaborates extensively with global research networks.