جست‌وجوی استاد و پژوهشگر

Ferdinandy Péterمشاهده پروفایل

استاد

• Molecular mechanisms of cardioprotection
• Translational cardiovascular sciences
• Cardiovascular pharmacology
• +۳ مورد دیگر

Péter Ferdinandy is a Professor of Pharmacology and former Vice Rector for Science & Innovations at Semmelweis University, Budapest. He concurrently holds a part-time professorship in Biochemistry at the University of Szeged. His roles include leading the Department of Pharmacology and Pharmacotherapy at Semmelweis and directing the Cardiovascular Research Group at Szeged. He is also the founder and CEO of Pharmahungary Group, a biotech company focused on R&D. Dr. Ferdinandy’s research focuses on molecular mechanisms of cardioprotection in comorbidities, translational cardiovascular sciences, and drug cardiotoxicity. His work bridges basic science and clinical applications, with emphasis on ischemia/reperfusion injury, diabetic cardiomyopathy, and immune checkpoint inhibitor-induced cardiotoxicity. Key achievements include being listed as a Highly Cited Researcher (2014–2024) and receiving the 1999 Young Investigator Award. He has held leadership roles in international societies, including chairing the ESC Working Group on Cellular Biology of the Heart and serving as president of the ISHR European Section. His educational background includes medical training, a PhD, and an MBA. He has contributed to over 200 publications, focusing on cardioprotective microRNAs (protectomiRs), drug development, and cardiovascular pharmacotherapy strategies. Current research explores therapeutic targets for heart failure and biomarkers for drug-induced cardiotoxicity.

Victoria Gossمشاهده پروفایل

پژوهشگر

• Respiratory Medicine
• Lipidomics
• Translational Medicine
• +۳ مورد دیگر

Dr. Victoria Goss PhD serves as Head of the Early Diagnosis and Translational Group at the University of Southampton, focusing on respiratory and metabolic research with clinical applications. Her work bridges laboratory science and patient care through translational approaches to respiratory disorders. Her research centers on lipid metabolism in respiratory diseases , particularly examining surfactant phospholipid kinetics in ventilated children, cellular phosphatidylcholine dynamics in ARDS, and lipidomic profiling in asthma. Key interests include pediatric pulmonology , asthma stratification , and early diagnostic biomarkers for conditions like pancreatic cancer. Her methodology integrates advanced lipidomics with clinical observational studies to identify treatable traits in chronic respiratory diseases. Analysis of her 10 most recent publications (2018-2024) reveals consistent focus on lipid-based mechanisms across respiratory conditions, with increasing emphasis on translational applications including diagnostic protocols (MecROX, DEPEND studies) and asthma endotyping. Her work frequently employs mass spectrometry lipid profiling and cellular kinetics analysis in both pediatric and adult populations. Current research initiatives include the MecROX study on oxidative stress in ventilated patients and DEPEND study for pancreatic cancer screening. She actively collaborates with European consortia like U-BIOPRED, reflecting her integration within international respiratory research networks.

Ulrich Eiselمشاهده پروفایل

استاد

• Neuroimmunology
• Alzheimer's Disease
• Neurodegenerative Disorders
• +۳ مورد دیگر

Ulrich Eisel is a Professor at the University of Groningen, Faculty of Science and Engineering, leading the Eisel Lab focused on Molecular Neurobiology and Neuroimmunology. His research investigates the role of TNF receptors in neurodegenerative diseases like Alzheimer’s and Parkinson’s, emphasizing translational therapies. He holds roles as course coordinator for Neuroscience Research and Molecular and Cellular Neuroscience, and lectures on Neurobiology and Aging. Education: PhD from Justus-Liebig-University Giessen and Tübingen (Germany), postdoctoral training at the NIH. His work integrates behavioral biology with neuroimmunology, exploring inflammatory pathways in disease progression. He serves on scientific advisory boards for BRAINS and Alzheimer Nederland, and chairs the BCN program committee. Research highlights include TNFR2 agonist therapies for Alzheimer’s and remyelination studies in MS models. Collaborations span global institutions, focusing on immune-neural interactions and drug development. Advising: Supervised 14 students and leads projects like 'Peripheral targeting of TNFR1' and 'ARTOS clinical development.' His lab aims to bridge basic science with clinical applications, addressing aging-related neurological disorders.

• HIV/AIDS Research
• Virology
• Immunology
• +۳ مورد دیگر

Andrew J. Henderson is a Professor at the Boston University Chobanian & Avedisian School of Medicine, holding roles as Assistant Dean of Graduate Medical Sciences and Co-Director of the BU PREP post-bac program. His primary research focuses on cellular mechanisms regulating HIV replication and transcription, with emphasis on T cell signaling, latency, and inflammatory processes. He earned his B.S., M.S., and Ph.D. in Microbiology from the University of California, Riverside. Research Interests: Dr. Henderson investigates how T cell signals and transcriptional machinery control HIV expression, particularly mechanisms underlying latency and viral persistence. His lab explores pathways involving CD28 costimulation, RNA polymerase II elongation, and chromatin modifications. These studies provide insights into broader topics like signal transduction, immune dysfunction, and inflammatory disorders. Key Contributions: His work includes identifying transcriptional checkpoints (e.g., NELF and Pcf11 factors), characterizing opioid use’s impact on HIV reservoirs, and developing CRISPR-based tools for HIV repression. He has also contributed to training programs in Liberia and Uganda through initiatives like the BU-UL Partnership and Fogarty grants. Awards: Notable recognitions include the Boston SciCafe Award, NIH study section leadership, and postdoctoral fellowships from the Leukemia Society of America and Aaron Diamond Foundation. Grants & Labs: Active grants include NIH-funded investigations into HIV latency, opioid effects on reservoirs, and global health partnerships (e.g., BULEEVR in Liberia). His lab collaborates with institutions like the Providence/Boston CFAR and the BU CTSI.

Wendy A. Goodmanمشاهده پروفایل

استادیار

• Immunology
• Endocrinology
• Gastroenterology
• +۷ مورد دیگر

Wendy A. Goodman, PhD is an Assistant Professor in the Department of Pathology at the Case Western Reserve University School of Medicine . She is also a Member of the Immune Oncology Program at the Case Comprehensive Cancer Center. Her research focuses on the role of steroid hormones (e.g., estrogens, androgens, progesterone) in immune regulation, particularly in mucosal tissues (e.g., intestinal mucosa) and maternal-fetal interface tissues (e.g., decidua). She employs preclinical mouse models and primary human cells/tissues to study mechanisms underlying immune homeostasis, chronic inflammation, and autoimmunity. Dr. Goodman’s education includes a Bachelor of Arts in Biology (2001) and a PhD in Pathology/Immunology (2010), both from Case Western Reserve University. Her research interests emphasize non-classical roles of sex hormones in adaptive and innate immune responses, including T-cell differentiation, regulatory T cell function, and immune cell/epithelial crosstalk. She investigates how local environmental cues in the gut and pregnancy tissues shape protective vs. pathogenic immune responses. Her work is supported by significant grants including an NIH/NIDDK R01 (2021-2026) and the March of Dimes Ohio Collaborative (2020-current) . Notable awards include the Michael E. Lamm Teaching Award (2018) and multiple Best Abstract Awards at conferences like FASEB GI Summer Conference (2017) and Advances in IBD (2015). She collaborates with institutions like Cincinnati Children’s Medical Center on pregnancy-related immune studies. Dr. Goodman has advised numerous research projects but no formal students are listed. Her lab actively explores estrogen/progesterone crosstalk during pregnancy, hormonal control of myeloid cells, and mechanisms driving IBD sexual dimorphism. Professional memberships include the American Association of Immunologists, Crohn’s and Colitis Foundation, and American Gastroenterological Association.

• Regenerative Lung Engineering
• Cell-to-Cell Communication Networks
• Systems Biology
• +۵ مورد دیگر

Dr. Micha Sam Brickman Raredon is an Assistant Professor in the Department of Anesthesiology at Yale School of Medicine. He leads the Raredon Laboratory, focused on regenerative lung engineering, systems biology, and bioengineered tissues. His work integrates computational tools like NICHES and Connectome to study cell-cell communication networks in lung tissue. Dr. Raredon holds MD/PhD degrees from Yale and a master's from MIT in Materials Science. His research spans lung vascular networks, fibrosis mechanisms, and translational applications in regenerative medicine. He is affiliated with the Vascular Biology and Therapeutics Program, Program in Translational Biomedicine, and Yale Combined Program in the Biological and Biomedical Sciences (BBS). Education: MD/PhD Yale University (2022/2021), MS Yale Engineering (2020), MPhil Yale (2020), MS MIT (2014), BS Yale & Cambridge (2011). Research Interests: Engineering functional lung tissues, decoding lung microvascular niches, single-cell systems biology, and applying machine learning to tissue regeneration. Key projects include developing algorithms for cell-cell interaction analysis and engineering patient-specific lung tissues. Recent work addresses hypoxia-induced cardiopulmonary damage and fibrotic lung diseases. Publications reflect interdisciplinary focus on lung biology, vascular integrity, and computational methods. Awards include the Draper Fellowship for tissue fabrication innovation and the Yale MD/PhD Thesis Prize. His lab collaborates with leading figures like Drs. Kaminski, Niklason, and Medzhitov. Advising and Grants: Mentors students in translational research. Lab develops ventilator splitting systems for disaster medicine and bioengineered lung models. Active in NIH-funded projects on lung regeneration and fibrosis. Labs/Teams: Raredon Lab at Yale Vascular Biology Program. Collaborations span Yale's Systems Biology, Immunobiology, and Biomedical Engineering departments.

• Pathology
• Oncology
• Hepatology
• +۵ مورد دیگر

Dr. Wenyi Luo is an Assistant Professor of Pathology at Yale School of Medicine, specializing in Anatomic Pathology and GI Pathology. He holds roles such as Director of the Immunohistochemistry Lab and has previously served at the University of Oklahoma Health Sciences Center (OUHSC) as Assistant Professor and Surgical Pathology Rotation Director. His research focuses on liver and gastrointestinal pathology, oncology, and cellular mechanisms in diseases like hepatocellular carcinoma and pancreatic cancer. Education: MD from Peking University Health Science Center (2004), PhD in Genetics from University of Alabama Birmingham (2010), and postdoctoral training at UAB and MD Anderson Cancer Center. Board certified in Anatomic and Clinical Pathology. Research interests include cancer biology, necroptosis regulation, liver fibrosis, and therapeutic strategies for cholestasis and cholangiopathy. His work integrates molecular pathology with clinical outcomes, emphasizing translational applications. Notable contributions include studies on macrophage-cancer cell interactions in pancreatic cachexia and miRNA roles in adipogenesis. Collaborations span hepatology, oncology, and metabolic disorders. He has no listed awards but maintains an active publication record in high-impact journals like Cancer Cell and Gastroenterology . Labs/Teams: Involved in gastrointestinal and liver pathology research at Yale, contributing to interdisciplinary projects in cancer biology and liver disease mechanisms.

• Metabolic Disorders
• Hepatology
• Lipid Metabolism
• +۳ مورد دیگر

Dr. Yingdong Zhu is a Researcher in the Department of Pediatrics at Yale School of Medicine, Yale University. His work focuses on metabolic disorders, particularly nonalcoholic steatohepatitis (NASH), lipid metabolism, and atherosclerosis. He investigates molecular mechanisms involving transcription factors (e.g., ATF3, HNF4α), miRNAs, and retinoic acid receptors in metabolic and liver diseases. His research integrates hepatocyte, adipocyte, and macrophage biology to elucidate pathways linking metabolic dysfunction to cardiovascular and hepatic pathologies. Research interests include: Adipose-liver crosstalk in metabolic disorders Molecular regulation of NASH progression Role of retinoid signaling in atherosclerosis MicroRNA-mediated liver disease mechanisms No specific awards or grants are listed, but his contributions are evident through recent publications in metabolic and hepatic research. Advising roles or lab affiliations are not explicitly stated in available texts.

Diana Tavares Ferreiraمشاهده پروفایل

استادیار

• Cellular and molecular mechanisms of axonal integrity
• RNA transport and regulation
• Computational neuroscience
• +۳ مورد دیگر

Diana Tavares Ferreira is an Assistant Professor of Neuroscience at the University of Texas at Dallas (UTD) within the School of Behavioral and Brain Sciences . Her research focuses on understanding cellular and molecular mechanisms underlying axonal integrity in sensory neurons, particularly in neuropathies and neurodegenerative diseases. Education & Training: Postdoctoral Researcher in Neuroscience at UTD (2023) PhD in Neuroscience from the University of Sheffield, UK (2018) PharmD/MS in Pharmaceutical Sciences from the University of Coimbra, Portugal (2013) Research Interests: RNA transport dynamics in distal axons Role of non-coding RNAs (e.g., miRNAs) in sensory neuron function Computational integration of multi-omics data (single-cell, spatial transcriptomics) Mechanisms of axon-soma communication and axonal regeneration Her lab, the Axon Biology and Neuroinformatics Lab , combines experimental and computational approaches to decode how RNA regulation impacts nerve health and disease. Awards & Recognition: Peter J. Dyck Abstract Prize (2022) for diabetic neuropathy research Catalyst Studentship (2016) from the Higher Education Funding Council for England Grants & Funding: Data Core UTD PRECISION Pain Center (National Institute of Neurological Disorders and Stroke, 2022–2027) Dr. Ferreira is currently accepting graduate students and collaborates on projects involving spatial transcriptomics and translational control in chronic pain mechanisms.

• Inflammation and cancer
• Novel biomarkers for therapy efficacy and resistance
• Translational cancer research
• +۳ مورد دیگر

Prof. Klaus Schulze-Osthoff serves as Director and Chair of the Department of Molecular Medicine at the University of Tübingen, Germany, a position he has held since 2008. He maintains dual affiliation as a Research Fellow at the German Cancer Research Center (DKFZ) in Heidelberg since 2012 and acts as Spokesperson for the German Consortium for Translational Cancer Research (DKTK) at the Tübingen Partner Site. Previously, he directed the Institute of Molecular Medicine at the University of Düsseldorf (2001-2008) and served as Scientific Director of the Comprehensive Cancer Center in Tübingen (2009-2013). His research spans critical areas in molecular oncology with particular emphasis on: Inflammation and cancer interactions Novel biomarkers for therapy efficacy and resistance Translational cancer research bridging basic science and clinical applications Tumor immunology mechanisms Tumor cell senescence as antitumor mechanism Apoptosis and cell death pathways Analysis of his publication history reveals a clear research trajectory: foundational work (1990s) establishing mitochondrial roles in apoptosis and caspase functions, followed by therapeutic applications (2000s) demonstrating caspase relevance in cancer treatment, and recent focus (2010s) on tumor cell senescence mechanisms including the identification of novel NF-κB co-activators and development of the world's first senescence PET tracer for clinical imaging. His scientific leadership has been recognized through: Steering committee membership at the National Center for Tumor Diseases (2021-present) Board membership in Cluster of Excellence IFIT (2019-present) Multiple Research Grant Awards from German Cancer Aid Foundation (2016, 2005, 2002) German University Medical Innovation Award (2008) Scientific advisory roles for pharmaceutical companies including Pfizer His research program has successfully translated basic discoveries into clinical applications, particularly through biomarker development for therapy monitoring and the creation of novel imaging techniques. He has secured sustained funding from major German research foundations and maintains active collaborations across European research institutions. His laboratory continues to investigate molecular mechanisms of tumor cell senescence and apoptosis with direct relevance to cancer therapy development. The Molecular Medicine Department he leads at Tübingen focuses on translating fundamental discoveries into clinical applications, with particular expertise in developing diagnostic tools like the senescence PET tracer currently in patient trials, and identifying novel therapeutic targets in tumor immunology and cell death pathways.

• Immunology
• Pediatric Gastroenterology
• Inflammatory Bowel Disease
• +۷ مورد دیگر

Janneke Samsom is a Full Professor in the Department of Pediatrics at Erasmus MC, a leading academic medical center in the Netherlands. Her work is centered at the intersection of pediatric immunology and gastroenterology, with a strong emphasis on understanding immune dysregulation in inflammatory bowel diseases. Her research interests include mucosal immunology , T-cell differentiation , inflammatory bowel disease (IBD) , Crohn’s disease , regulatory and pathogenic T cells , and the discovery of biomarkers for treatment response . She investigates how memory T cells and plasma proteins can be profiled to define patient immunotypes, enabling personalized therapeutic strategies. The recent trend in her publications shows a strong focus on integrating proteomic and immunophenotypic data to predict disease progression and treatment outcomes in both pediatric and adult IBD. Her work spans from fundamental immunology to clinical translation, including case studies in rare immune disorders. Inflammatory Bowel Disease (IBD) Crohn's Disease Ulcerative Colitis T-cell Immunology Biomarker Discovery Pediatric Autoimmune Disorders She has supervised numerous junior researchers and students, contributing to a robust body of supervised academic work. Her collaborative network extends across Europe, with active research partnerships in immunology and gastroenterology. Dr. Samsom leads a research group focused on pediatric immune-mediated gastrointestinal diseases, contributing significantly to both national and international research initiatives.

• Cell Biology
• Molecular Biology
• Mitochondrial Biology
• +۵ مورد دیگر

Dr. Danilo Faccenda is a Lecturer in Biochemistry at the University of Hertfordshire's Department of Clinical, Pharmacological and Biological Sciences, within the School of Life and Medical Sciences. His research focuses on mitochondrial function's role in disease pathways, particularly cellular stress responses and mitochondria-nucleus communication in neurobiology and gastrointestinal inflammation. BSc Cell and Molecular Biology (University of Bologna, 2007) MSc Molecular Biotechnologies (University of Bologna, 2011) PhD Cell Biology (Royal Veterinary College, University of London, 2016) Research interests include mitochondrial ultrastructure/function relationships, homeostasis signaling pathways, and age-related disease mechanisms. Current projects investigate retrograde signaling pathways in neuronal cells and mitochondria's role in gastrointestinal inflammatory conditions. He leads a UKRI-funded project exploring nucleus-associated mitochondria in cellular signaling (2024–2027). Recent publications analyze mycotoxin impacts on gut health and lung cancer recurrence factors post-surgery. His work combines molecular biology, cellular pathology, and translational medicine approaches.

Elisa Gomez Perdigueroمشاهده پروفایل

عضو هیئت علمی

• Immunology
• Developmental Biology
• Cell Biology
• +۹ مورد دیگر

Elisa Gomez Perdiguero is a Permanent Researcher at the Institut Pasteur in Paris, affiliated with the Membrane, Cytoskeleton and Cell Division unit. She leads the research group focused on the development, maintenance, and functions of tissue-resident macrophages, with a particular emphasis on their embryonic origins and roles in homeostasis and tissue repair. Her work bridges immunology, developmental biology, and cell biology, and she is the Principal Investigator of the ERC-funded project 'ResidentMacroPhage'. Her research primarily investigates the role of yolk sac-derived erythro-myeloid progenitors (EMPs) in generating tissue-resident macrophages such as microglia, Kupffer cells, and Langerhans cells, which self-maintain independently of hematopoietic stem cells (HSCs). She uses mouse and zebrafish models, along with advanced techniques like flow cytometry, lineage tracing, and transgenesis, to explore the ontogeny and functional specialization of macrophages during development and in response to injury. The trends in her recent publications highlight a consistent focus on developmental hematopoiesis, macrophage heterogeneity, and the interplay between macrophages and endothelial cells. Her work has demonstrated the critical role of early macrophage waves in shaping immune and vascular development, with implications for regenerative medicine and inflammatory diseases. Scientific awards and recognitions include: ERC-2016-StG _ResidentMacroPhage – Development, Maintenance and Functions of Resident Macrophages She has actively mentored numerous PhD students and postdoctoral researchers, including Lorea Iturri, Rebeca Ponce Landete, Alina Sommer, and others. Her lab has received funding from major programs such as LabEx Revive and the IP Stem Cell Initiative, supporting research in regenerative biology and medicine. She is currently recruiting for fully funded postdoctoral and PhD fellowships. Elisa Gomez Perdiguero's team collaborates within transversal programs such as 'Mother and Child Health' and participates in the broader Institut Pasteur ecosystem focused on precision medicine and open science.

Lucie Pedutoمشاهده پروفایل

پژوهشگر

• Cancer biology
• Immunology
• Stromal microenvironment
• +۱۱ مورد دیگر

Lucie Peduto is a Principal Investigator and Structure Manager at the Institut Pasteur in Paris, where she leads a research team investigating the role of stromal and perivascular cells in immunity, inflammation, regeneration, and cancer. Her work focuses on understanding how the stromal microenvironment regulates intestinal homeostasis, tumor progression, and immune responses. Her research interests include: Cancer biology and tumor microenvironment Intestinal immunity and barrier function Mesenchymal and perivascular stromal cells Inflammation and fibrosis Regenerative mechanisms and tissue repair Immune cell-stromal cell crosstalk The recent publications highlight a strong focus on stromal regulation in immunity and cancer, with particular emphasis on PDGFRα+ mesenchymal cells, intestinal barrier integrity, and macrophage interactions. Her work integrates genetic models, organoid systems, and immunological assays to dissect molecular and cellular mechanisms in vivo. Scientific awards and recognitions: ERC Proof of Concept Grant 2023 Dr. Peduto supervises several postdoctoral fellows and PhD students, indicating an active mentoring and training role. She leads multiple funded projects, including ERC-CoG-PERIF on perivascular cells in inflammation and regeneration. Her research is supported by major initiatives at the Institut Pasteur, including the Cancer Initiative and stem cell programs. She collaborates with other leading immunologists and cell biologists at the institute and internationally.

• Cancer Biology
• Thrombosis and Hemostasis
• Melanoma
• +۴ مورد دیگر

Alexander Bauer is a researcher at the Clinic and Polyclinic for Dermatology and Venereology within the University Medical Center Hamburg-Eppendorf (UKE). His work focuses on the intersection of oncology , thrombosis , and endothelial cell interactions in cancer progression. Key Research Areas: Cancer cell-blood cell interactions von Willebrand factor (VWF) in metastasis Immunothrombotic mechanisms in melanoma Brain metastasis microenvironment Notable Collaborations: ADOReg skin cancer registry International translational cancer research teams Major Contributions: Elucidated VWF's dual role in tumor cell arrest and metastatic colonization Identified MMP9's impact on blood-brain barrier integrity Demonstrated immunothrombosis as a therapeutic avenue in melanoma