معرفی
Lucie Peduto is a Principal Investigator and Structure Manager at the Institut Pasteur in Paris, where she leads a research team investigating the role of stromal and perivascular cells in immunity, inflammation, regeneration, and cancer. Her work focuses on understanding how the stromal microenvironment regulates intestinal homeostasis, tumor progression, and immune responses.
Her research interests include:
- Cancer biology and tumor microenvironment
- Intestinal immunity and barrier function
- Mesenchymal and perivascular stromal cells
- Inflammation and fibrosis
- Regenerative mechanisms and tissue repair
- Immune cell-stromal cell crosstalk
The recent publications highlight a strong focus on stromal regulation in immunity and cancer, with particular emphasis on PDGFRα+ mesenchymal cells, intestinal barrier integrity, and macrophage interactions. Her work integrates genetic models, organoid systems, and immunological assays to dissect molecular and cellular mechanisms in vivo.
Scientific awards and recognitions:
- ERC Proof of Concept Grant 2023
Dr. Peduto supervises several postdoctoral fellows and PhD students, indicating an active mentoring and training role. She leads multiple funded projects, including ERC-CoG-PERIF on perivascular cells in inflammation and regeneration. Her research is supported by major initiatives at the Institut Pasteur, including the Cancer Initiative and stem cell programs. She collaborates with other leading immunologists and cell biologists at the institute and internationally.
