جست‌وجوی استاد و پژوهشگر

• Immunology
• Hematology
• Molecular Biology
• +۳ مورد دیگر

Dr. Reiner Mailer is a researcher at the Institute of Clinical Chemistry and Laboratory Medicine within the University Medical Center Hamburg-Eppendorf (UKE), affiliated with the Medical Faculty at the University of Hamburg. His work bridges immunology, hematology, and cardiovascular research with a focus on molecular mechanisms. PhD in Natural Sciences ( Dr. rer. nat. ) ORCID: 0000-0001-8279-3355 Research Interests span immunology (particularly thromboinflammatory processes), molecular biology of vascular systems, and mechanisms of T-cell-mediated thrombosis. He investigates how polyphosphates regulate vascular immunity and clotting, and explores novel anticoagulant therapies. Recent Publications analyze NET formation in sepsis, thrombogenicity of magnesium stents, FOXP3 isoform dynamics, phosphodiesterase roles in lymphatics, and thromboinflammatory pathways in cardiovascular diseases, with a recurring focus on immune-thrombosis interactions. Professional Memberships include the European Society for Immunodeficiencies , German Society for Immunology , and Society for Thrombosis and Hemostasis Research , reflecting his interdisciplinary expertise. Laboratory Affiliation is with the Institute of Clinical Chemistry and Laboratory Medicine at UKE, a hub for translational research connecting biochemical mechanisms to clinical diagnostics and therapies.

Carsten Schultzمشاهده پروفایل

استاد

• Chemical Biology
• Biochemistry
• Cellular Signaling
• +۳ مورد دیگر

Carsten Schultz is a Professor and Chair at Oregon Health & Science University (OHSU) in the Department of Chemical Physiology & Biochemistry. He co-founded Araxa Bioscience GmbH (2019) and SiChem GmbH (2001), and previously held senior scientist and group leader roles at EMBL Heidelberg (2001-2019). He has served as Associate Editor for Chemical Science since 2015 and contributed to over 180 publications in top-tier journals including Nature, Science, and Angewandte Chemie. His research focuses on lipid signaling , phosphoinositide dynamics , and optical uncaging techniques to study cellular processes. He has developed chemical tools for live-cell imaging and signal transduction, with applications in exocytosis , metabolic regulation , and inflammatory diagnostics . 2013: Metropolregion RN Innovation Price 2012: Heidelberg Molecular Life Science Award 1993-1996: DFG Habilitation Fellowship His editorial roles span ChemBioChem, ACS Chemical Biology, and Current Methods in Chemical Biology. He has supervised 27 PhD students and 33 postdocs, with 9 patents to his name.

Melanie Markمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Cerebellar Disorders
• +۴ مورد دیگر

Prof. Dr. Melanie Mark is a faculty member at Ruhr University Bochum, affiliated with the Faculty of Biology and Biotechnology and the Department of General Zoology and Neurobiology . She leads the Behavioral Neurobiology Group , focusing on the cerebellum's role in neurological disorders like ataxia, stress-induced dystonia, and absence epilepsy, as well as the serotonergic system's regulation of aggression and cerebellar contributions to fear and anxiety. Research Highlights: Developed transgenic mouse models for Episodic Ataxia type 2 and Spinocerebellar Ataxia type 6. Investigated RGS2 overexpression and P/Q-type calcium channel knockout in serotonergic neurons to study aggression. Explored cerebellar mechanisms in fear conditioning using optogenetics and pharmacology. Academic Contributions: Active in teaching (e.g., courses in Behavioral Neurobiology, Neuroscience, and Experimental Medicine). Collaborates with the International Graduate School of Neuroscience and Research Department of Neuroscience . Techniques: Optogenetics Genetic modeling Pharmacology Synaptic transmission analysis Email: melanie.mark@ruhr-uni-bochum.de | ORCID

Felix Meissnerمشاهده پروفایل

پژوهشگر

• Systems Immunology
• Proteomics
• Inflammation Regulation
• +۳ مورد دیگر

Felix Meissner is a Principal Investigator at the Institute of Innate Immunity (University Hospital Bonn), leading the Department of Systems Immunology and Proteomics since 2021. He studied biochemistry at the Free University of Berlin and Scripps Institute, earned a PhD at MPI for Infection Biology, and conducted postdoctoral research at MPI of Biochemistry and UCSF. Education : Biochemistry (Free University of Berlin, Scripps Institute); PhD (MPI for Infection Biology) Career : Postdoc (MPI Biochemistry, UCSF); Independent Group Leader (MPI Martinsried); Department Head (III Bonn since 2021) His research focuses on immune signaling circuits that regulate inflammation using mass spectrometry proteomics , with applications in chronic diseases and cancer . The lab has pioneered unbiased secretomics and EASI-tag technologies for quantitative proteomics. Recent publications reveal trends in spatial proteomics for cancer subtyping, intercellular communication networks in immunity, and apoptosis regulation in chemotherapy response. Collaborative DFG-funded projects (SFB 1335, SFB 1454) and BMBF grants support his work. The lab team includes PhD students like Diana Fink , postdocs such as Felix Weiss , and alumni like Jingyuan Cheng . Based at the Biomedical Center (BMZ 2) in Bonn, his group also operates at MPI Martinsried .

Noelia Alonso Gonzalezمشاهده پروفایل

استاد

• Immunology
• Macrophage Biology
• Inflammation Research
• +۴ مورد دیگر

Prof. Dr. Noelia Alonso Gonzalez is a Professor at the University of Münster's Faculty of Medicine, where she leads the Alonso Gonzalez Group focused on "Mechanisms of Macrophage Plasticity" at the Institute of Immunology. She joined the university in 2017 as a Researcher and became a Junior Group Leader in 2018 through the Gerty Cori Programme, a career development initiative within the "Cells in Motion" research network designed to promote gender equality in science. Her research investigates how inflammation resolves before becoming chronic or life-threatening, with particular emphasis on macrophages - immune cells that eliminate dead cells and produce tissue-repair molecules. She studies how different macrophage populations recognize and adapt to inflammatory processes across various organs, employing state-of-the-art genomics, imaging approaches, and in vivo disease models. Her work combines transcriptional regulation studies with cellular imaging to understand macrophage-lymphocyte interactions during development and inflammation. Dr. Alonso Gonzalez's publications reveal a consistent focus on macrophage biology, with recent work expanding into neuroimmunology, thrombosis, and infectious disease complications. Her research shows strong interdisciplinary connections between immunology, molecular biology, and tissue-specific inflammatory responses, with particular emphasis on lipid metabolism, transcription factor regulation, and cellular plasticity. Humboldt Research Fellowship recipient (2017) Active participant in the "Cells in Motion" interdisciplinary research center Supervisor in the CiM-IMPRS Graduate Programme Recipient of third-party funding for Collaborative Research Centers As both a scientist and mother of two young children, Dr. Alonso Gonzalez actively engages with university childcare services while advocating for equitable sharing of family responsibilities. She serves as a role model for junior scientists, particularly women, encouraging them to pursue leadership positions in academic research despite societal expectations about gender roles.

• Diabetes research
• Pancreatic beta cells
• Insulin secretion
• +۴ مورد دیگر

Professor Michele Solimena is a leading researcher at the DZD-Paul-Langerhans-Institute Dresden (PLID), which operates at the Carl Gustav Carus University Hospital of the Technische Universität Dresden. His work focuses on advancing our understanding of pancreatic beta cell biology and diabetes pathophysiology through multiple research initiatives. His research interests span several critical areas including diabetes research, pancreatic beta cell function, insulin secretion mechanisms, metabolic diseases, cell biology, regenerative medicine, and endocrinology. Professor Solimena employs advanced molecular, biophysical, and genomic approaches to investigate fundamental processes in islet cell biology. His publication record demonstrates a consistent focus on next-generation sequencing of islet cells, molecular mechanisms of insulin secretion, stress responses in beta cells, and regenerative approaches for diabetes treatment. His work bridges basic science with translational applications, particularly in the areas of islet cell transplantation and novel therapeutic strategies for metabolic diseases. Professor Solimena has received significant research funding through the German Research Foundation (DFG), including ongoing projects on next-generation sequencing of human islet cells and participation in International Research Training Groups focused on metabolic diseases. His previous work includes leadership in the Center for Regenerative Therapies Dresden and contributions to graduate education in biomedicine. His research program represents a significant contribution to diabetes science, with implications for understanding disease mechanisms and developing novel therapeutic approaches for metabolic disorders.

• Immunology
• Stem Cell Biology
• Hematopoiesis
• +۵ مورد دیگر

Claudia Waskow is a Professor at Friedrich Schiller University Jena, working within the Faculty of Biosciences at the Institute of Biochemistry and Biophysics. Her research focuses on immunological processes, stem cell biology, and molecular mechanisms underlying various cellular functions. Her primary research interests include immunology, stem cell biology, hematopoiesis, epigenetics, immunodeficiencies, molecular biology, cell biology, and regenerative medicine. Dr. Waskow investigates mechanisms of homeostatic proliferation of peripheral T cells, cellular and molecular components of functional niches for hematopoietic stem cells, and treatment approaches for primary immunodeficiencies through gene-edited lymphoid progenitor cells. Her work bridges fundamental biological processes with potential clinical applications, particularly in understanding immune system development and function. Dr. Waskow has received significant research funding through the German Research Foundation (DFG), managing both ongoing and completed projects. Her current research includes investigating the mechanisms of homeostatic proliferation of peripheral T cells in the absence of the epigenetic regulator SETD1A. Previously, she has led projects examining dendritic cell development in growth factor receptor mutant mice, functional niches for hematopoietic stem cells, and the cellular origin of osteoclasts. She has also participated in the Center for Regenerative Therapies Dresden (CRTD) and managed subprojects related to inflammatory circuits and immunogenicity prediction.

• Immunology
• Gastroenterology
• Hepatology
• +۶ مورد دیگر

Prof. Dr. Samuel Huber is a leading academic in gastroenterology and immunology at the University of Hamburg's Faculty of Medicine, serving as Director of the I. Department of Medicine and Head of Molecular Gastroenterology and Immunology. His work focuses on immune-mediated diseases of the gastrointestinal tract and liver, particularly inflammatory bowel diseases (IBD), primary sclerosing cholangitis (PSC), and hepatocellular carcinoma (HCC). He has pioneered research on cytokine networks (e.g., IL-22, IL-10, IFNγ) and microbiota interactions in disease pathogenesis. Roles: Director, Head of Molecular Gastroenterology & Immunology, Medical Specialist in Internal Medicine/Gastroenterology Affiliations: University Medical Center Hamburg-Eppendorf (UKE), Academy of Biomedical and Health Sciences Research interests include T cell plasticity, tumor immunology, and regenerative processes in the liver and gut. Key achievements include elucidating the role of IL-22 in cancer metastasis and the protective effects of microbiota-derived metabolites on chemotherapy efficacy. Recipient of prestigious awards such as the ERC Consolidator Grant (2019) and Theodor-Frerichs-Preis (2017). His lab investigates translational approaches to autoimmune liver diseases and leverages single-cell technologies to model IBD and HCC progression. Current projects address liver metastasis mechanisms, microbiota-host interactions, and immune checkpoint therapies' safety in chronic liver diseases. Collaborates with the European Liquid Biopsy Society (ELBS) on liquid biopsy diagnostics for hepatocarcinogenesis.

Argyris Papantonisمشاهده پروفایل

استاد

• Epigenetics
• Genome Architecture
• Chromatin Folding
• +۲ مورد دیگر

Argyris Papantonis is Professor of Translational Epigenetics at the University Medical Center Göttingen, Germany, leading a research group at the Institute of Pathology. His work focuses on understanding how genome architecture in 3D nuclear space regulates gene expression during cellular responses to developmental cues, disease states, and aging processes. The laboratory investigates chromatin folding dynamics using advanced genomic and imaging approaches. Research interests include epigenetic regulation of gene expression, chromatin topology dynamics during cellular differentiation, nuclear organization principles, and mechanisms of cellular senescence. The group develops methods to study spatial genome organization and its functional consequences. Recent publications reveal fundamental insights into CTCF/cohesin-mediated chromatin looping, enhancer-mediated gene activation mechanisms, epigenetic drivers of cellular aging, and the role of genome architecture in cancer biology. This work combines computational genomics with experimental approaches to develop predictive models of cellular behavior. Dr. Papantonis maintains collaborations across computational, molecular, and clinical disciplines and has developed specialized techniques for studying active transcription sites and chromatin interactions in mammalian cells.

• Pharmacology
• Cellular Signal Transduction
• Inflammation
• +۳ مورد دیگر

Prof. Dr. Günther Weindl is a Professor at the Pharmaceutical Institute, University of Bonn. His research focuses on experimental pharmacology and cellular signal transduction, particularly understanding molecular mechanisms of drugs involved in inflammatory and immunological processes. Current investigations examine immunomodulatory drug characterization, Toll-like receptor modulators, synthetic peptides, autophagy regulation, and lysosomotropic drug mechanisms. Research interests span pharmacology, inflammation biology, and cellular signaling pathways, with emphasis on developing therapeutic strategies for inflammatory diseases. Work integrates immunopharmacology concepts with molecular characterization of drug-receptor interactions. Publications demonstrate consistent focus on inflammatory pathways and immunomodulation, with recent work exploring oxidative stress responses, TLR signaling inhibition, peptide-mediated wound healing, and glucocorticoid interactions.

Daniela Yildizمشاهده پروفایل

استاد

• ADAM Proteases
• Inflammatory Diseases
• Pharmacology
• +۵ مورد دیگر

Daniela Yildiz is a Professor of Molecular Pharmacology at Saarland University, affiliated with the Center for Molecular Signaling and the Preclinical Center for Molecular Signal Processing (PZMS). Her research focuses on ADAM proteases in inflammatory diseases, particularly their roles in lung and cardiovascular pathologies, with emphasis on developing targeted therapies and reducing reliance on animal models. Appointed as University Professor (2024) Junior Professor at Saarland University (2018-2024) Education: RWTH Aachen (Diploma, 2005; PhD, 2009) Research interests span: ADAM protease functions in infectious and chronic inflammation Organoids and organ-on-a-chip for personalized drug testing Inter-organ communication via extracellular vesicles Gender-sensitive biology in disease susceptibility Proteolytic enzyme regulation in immunology Scientific contributions include: DFG-funded project on tissue-specific ADAM protease roles BMBF grant (16LW0140K) Key publications on ADAM10/ADAM17 in inflammation and infection Students and team members include: PhD candidates: Ahmad Aljohmani, Mariana Guedes MD/PhD students: Moritz Jesel, Noah Andres Recent graduates: Thea Katharina Funke (MD/PhD), Hakon Heinze (MD/PhD) Her group collaborates internationally through strategic alliances like the University of the Greater Region and Transform4Europe, maintaining labs at Saarland University Hospital (Homburg) and Campus Saarbrücken.

Isabelle Heinischمشاهده پروفایل

پژوهشگر

• Biology Education
• Higher Education Evaluation
• Allergy & Asthma Research
• +۳ مورد دیگر

Dr. Isabelle Heinisch ist eine akademische Mitarbeiterin in der Abteilung Biologie an der Pädagogische Hochschule Schwäbisch Gmünd . Mit umfassender Erfahrung in Hochschuldidaktik und biomedizinischer Forschung verbindet sie ihre Expertise in der Entwicklung qualitativer und quantitativer Evaluationsinstrumente in der Biologiedidaktik. Sie ist seit April 2022 an der Pädagogischen Hochschule tätig und führte zuvor Projekte zur biodiversitätsbezogenen Kommunikation sowie in der Hochschuldidaktik durch. Gentechnik Humanbiologie Biologiedidaktik Hochschuldidaktik Evaluationsmethoden Allergie- und Asthmaforschung Ihre Forschungsschwerpunkte umfassen die Entwicklung von Evaluationsinstrumenten in der Biologiedidaktik, mit besonderem Fokus auf kompetenz- und outcome-orientierte Lehrmethoden. In der Biomedizin untersuchte sie die Regulation von Apoptose durch CD137-Rezeptoren sowie deren Rolle bei allergischen Erkrankungen. Aktuelle Arbeiten befassen sich mit biodiversitätsfördernden Maßnahmen im Obstbau. Die 15 wichtigsten Publikationen zeigen eine Entwicklung von grundlegenden biomedizinischen Arbeiten (2000-2002) über hochschuldidaktische Projekte (2012-2016) bis hin zu angewandten Agrarwissenschaften (2021). Die Arbeiten decken Themen von Apoptosemechanismen über Lehrmethoden bis zu nachhaltiger Landwirtschaft ab. Ihre akademische Laufbahn umfasst Tätigkeiten an renommierten Institutionen wie der University of Edinburgh und dem Schweizer Institut für Allergie- und Asthmaforschung. Sie betreute Bachelorarbeiten zu Themen wie ergotherapeutischen Schulungen älterer Menschen und der interprofessionellen Zusammenarbeit in Krankenhäusern.

Benno Kuropkaمشاهده پروفایل

پژوهشگر

• Proteomics
• Mass Spectrometry
• Quantitative Proteomics
• +۴ مورد دیگر

Benno Kuropka is a Researcher in the Freund Group at the Freie Universität Berlin ’s Department of Biology, Chemistry, Pharmacy , specializing in proteomics and mass spectrometry . He joined the group in 2016 after completing his postdoctoral research at Bayer Pharma AG. His work focuses on quantitative proteomics , protein-protein interactions , and intact protein mass analysis . Education: Studied Biochemistry at Freie Universität Berlin (B.Sc.), conducted his Ph.D. under Dr. Eberhard Krause (FMP Berlin) and Prof. Christian Freund, and completed postdoctoral studies at Bayer Pharma AG. Research Interests : Kuropka’s research integrates mass spectrometry with structural biology to investigate protein dynamics, immune signaling (T cell biology), and antimicrobial resistance mechanisms. He also contributes to the Core Facility BioSupraMol and the SFB 958 project, managing high-resolution mass spectrometry instruments. Awards & Grants : No awards explicitly listed, but his contributions to collaborative projects (e.g., SFB 958) reflect sustained research excellence. Labs & Teams : Leads proteomics initiatives in the Freund Group, collaborating with interdisciplinary teams on projects involving protein interactomes and drug resistance.

Johanna Schottمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Immunology
• Gene Expression Regulation
• +۳ مورد دیگر

Johanna Schott is a Researcher in the Division of Biochemistry at the Mannheim Institute for Innate Immunoscience, part of the Medical Faculty Mannheim at Heidelberg University. Her work focuses on understanding the dynamics of mRNA expression during innate immune responses, particularly how transcription, mRNA processing, and translation interact under inflammatory conditions. She develops experimental and computational methods to dissect post-transcriptional regulatory mechanisms. Her research interests include molecular biology, immunology, and translational control, with emphasis on how ribosomal loading and CDK1 signaling influence protein synthesis. Key projects explore the role of mRNA modifications and RNA-binding proteins like Roquin in regulating immune responses. Her most recent studies highlight CDK1’s role in coupling cell proliferation with protein synthesis, revealing its impact on 5’TOP mRNA translation and interactions with LARP1. This work bridges cell cycle regulation and translational control, offering insights into cellular homeostasis and potential therapeutic targets. Despite her significant contributions, no scientific awards or grants are explicitly listed in the provided materials. She collaborates with teams at the Center for Molecular Biology of Heidelberg University and the DKFZ-ZMBH Alliance, contributing to a multidisciplinary research environment.

• Immunology
• T cell biology
• Inflammation
• +۵ مورد دیگر

Nicola Gagliani is a Professor at the Universitätsklinikum Hamburg-Eppendorf (UKE), where he leads research at the Institute of Inflammation and Carcinogenesis. His work focuses on the intersection of immunology, inflammation, and cancer development, with particular expertise in T cell biology, gut immunity, and the microbiome's role in disease processes. Over the past decade, he has established himself as a leading researcher in understanding how immune responses shape inflammatory conditions and cancer progression. His research interests span several interconnected domains within immunology: T cell biology and plasticity - Investigating how T cells differentiate, adapt, and function in various tissue environments Gut-liver axis immunology - Exploring the complex immune interactions between the gastrointestinal tract and liver Microbiome-immune system crosstalk - Understanding how commensal bacteria shape immune responses and disease outcomes Cancer immunology - Examining how immune responses influence tumor development and treatment efficacy Autoimmune mechanisms - Studying the pathological processes underlying conditions like inflammatory bowel disease and primary sclerosing cholangitis Analysis of his recent publications reveals a strong focus on tissue-specific immune responses, particularly in the gut and liver. His work increasingly incorporates advanced techniques like single-cell CRISPR screening and spatial transcriptomics to unravel the complexity of immune cell behavior in different disease contexts. A notable theme is the investigation of how environmental factors, particularly diet and the microbiome, influence immune cell function and disease progression. His research has significant translational potential, with several studies directly addressing therapeutic implications for cancer treatment and inflammatory conditions. Professor Gagliani has received substantial research funding, as evidenced by his involvement in multiple collaborative projects including: SFB 1648/1 C03: Actionable metabolite supplements to improve treatment response in pancreatic cancer Tracking adaptation of naïve T cells to distinct organs to decode organ-specific immune diseases IT-COVID-19 – Identification of immunological therapy options for Covid-19 lung disease SFB 1328 A14 SFB 841 - P4 - 3. Förderung His research group appears to be highly collaborative, with frequent co-authorship across multiple institutions and disciplines. While specific student names aren't listed in the provided information, his position as a professor suggests he mentors doctoral students and postdoctoral researchers in immunology and related fields. His laboratory likely focuses on cellular and molecular immunology techniques to investigate tissue-specific immune responses in both health and disease states.