جست‌وجوی استاد و پژوهشگر

Leslie Chanمشاهده پروفایل

استادیار

• Drug Delivery
• Biomaterials Development
• Chemical Biology
• +۵ مورد دیگر

Dr. Leslie Chan is an Assistant Professor in the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology's College of Engineering and Emory University School of Medicine. Her research program integrates core and emerging principles from drug delivery, biomaterials development, and chemical biology to engineer diagnostic and therapeutic solutions for infectious disease, microbiome dysbiosis, and inflammatory diseases. Dr. Chan received her educational training from prestigious institutions: B.S. in Biomedical Engineering from Georgia Tech (2009) Ph.D. in Bioengineering from the University of Washington (2015) with Professor Suzie Pun Postdoctoral training at Massachusetts Institute of Technology with Professor Sangeeta Bhatia Dr. Chan's research focuses on immunoengineering and nanomedicine, with additional interests in smart materials, infectious disease, microbiome, and inflammation. Her lab uses molecular and nanoscale engineering to develop biosensing and drug delivery strategies to address gastrointestinal diseases, infections, and autoimmune disorders. The lab is housed in the Petit H. Parker Institute for Bioengineering and Bioscience (IBB) on the Georgia Tech campus, where they are part of a vibrant, collaborative research community. Her recent publications demonstrate a strong focus on activity-based diagnostics for infectious disease and microbiome health, nanoscale materials for detecting and treating infections, and engineering synthetic breath biomarkers for respiratory disease. Her work spans from fundamental biomaterials development to translational applications for clinical impact. Dr. Chan has been recognized with significant awards including: NIH K99/R00 Pathway to Independence Award Caltech Young Investigator Lecturer Award in Engineering and Applied Sciences Dr. Chan is actively mentoring graduate students including Jaibyung Choi, Vishal Manickam, and Khoi Le. Her lab is currently developing biosensing and drug delivery strategies for gastrointestinal disease, ingestible probes for breath-based detection of gastrointestinal diseases, and probes for breath-based detection of respiratory disease. The Chan Lab is also hiring postdoctoral fellows and research technicians with backgrounds in drug delivery, biomaterials, chemistry, or related areas.

• Cardiovascular Inflammation
• Neuro-immune crosstalk
• Bioelectronic Medicine
• +۵ مورد دیگر

Peder Olofsson is a Professor at Karolinska Institutet's Department of Medicine, Solna, leading the Inflammation Neuroscience research group. He holds dual appointments as Professor in Bioelectronic Medicine at Karolinska and previously served at the Feinstein Institute for Medical Research (2015–2023). His work focuses on neuro-immune interactions in cardiovascular diseases, combining immunology, neuroscience, and bioengineering. Education: MD and PhD from Karolinska Institutet (2008) Docent qualification in Medicine (2018) Research Interests: Dr. Olofsson investigates neural regulation of inflammation using bioelectronic medicine approaches. His lab explores how peripheral nerves control vascular inflammation and atherosclerosis, with breakthrough discoveries on vagus nerve stimulation's role in resolving inflammation. Key focus areas include neuroimmune interfaces, bioelectronic therapies, and developing non-invasive nerve stimulation technologies. Publications: Recent work highlights include landmark studies in Science , Nature , and Proceedings of the National Academy of Sciences , emphasizing inflammation resolution mechanisms and neural pathways in cardiovascular disease. Awards: Recipient of the Swedish Heart and Lung Foundation's Large Research Grant (2023) for pioneering work on nerve signals in atherosclerosis. Grants/Teams: Collaborates with engineers from KTH and Linköping University through MedTechLabs. Current projects involve developing bioelectronic devices and AI-driven therapies. Lab members include PhD students Wanmin Dai, Ting Liu, and Qi Guo, supervised by assistant professors Laura Tarnawski and Vladimir Shavva. Labs/Teams: Leads the Inflammation Neuroscience Team within the Division of Cardiovascular Medicine. Key collaborations include the Feinstein Institute and University of Bonn.

Wen Luمشاهده پروفایل

استادیار

• Cytoskeleton
• Developmental Biology
• Neurobiology
• +۴ مورد دیگر

Wen Lu, PhD is a Research Assistant Professor in the Department of Cell and Developmental Biology at Northwestern University's Feinberg School of Medicine. Her primary research focuses on cytoskeletal regulation and molecular motor coordination in super-large cells including oocytes and neurons, utilizing Drosophila melanogaster as a model organism. She employs high-resolution live microscopy, genetic engineering, optogenetics, and pharmacological manipulations to investigate microtubule and F-actin dynamics in cellular development and regeneration. Her educational background includes a BS from Peking University (2004) and a PhD from The University of Chicago (2010), followed by postdoctoral training at Northwestern University Feinberg School of Medicine. Dr. Lu maintains active affiliations with the American Society for Cell Biology (2019-2024) and the Genetics Society of America (2022-2023), and serves on the FlyBase Community Advisory Group since 2014. Research interests center on cytoskeletal dynamics in cellular polarization, with particular emphasis on oocyte specification, growth mechanisms, and neuronal regeneration after injury. Her work bridges developmental biology and neurobiology through innovative imaging techniques that reveal molecular transport mechanisms in cellular systems. Current investigations explore microtubule movement regulation and the interplay between cytoskeletal elements during critical developmental processes. Publication trends demonstrate strong interdisciplinary focus spanning cell biology, neurobiology, and imaging sciences, with recent work increasingly incorporating translational elements in ophthalmology and oncology. Her articles reveal consistent methodological innovation in live-cell imaging and genetic manipulation techniques applied to fundamental biological questions. Winner 2025 Drosophila Art Contest, The FlyStuff / Genesee Scientific Team Winner of CDB Graphic Design Contest, CDB Special Events Committee (2024) Winner in Category 2, Microscopy Image Competition 2024, ProteinTech Group 2nd Prize in Published Category, Microscopy Today Micrograph Awards (2024) BINA 2022 Image Contest- People's Choice Award, BioImaging North America Dr. Lu serves on the FlyBase Community Advisory Group and maintains industry relationships including ownership in Quantum Music LLC. Her laboratory work integrates advanced microscopy with genetic models to address fundamental questions in cellular organization, with potential implications for understanding developmental disorders and neurodegenerative conditions.

Curtis Huttenhowerمشاهده پروفایل

استاد

• Computational Biology
• Bioinformatics
• Human Microbiome
• +۴ مورد دیگر

Dr. Curtis Huttenhower is a Professor of Computational Biology and Bioinformatics at Harvard T.H. Chan School of Public Health , with dual appointments in the Department of Biostatistics and Department of Immunology and Infectious Diseases . His research focuses on computational methods for microbial community analysis, human microbiome public health implications, and machine learning applications in genomics. Education: B.S. (2000) from Rose-Hulman Institute of Tech, M.S. (2003) from Carnegie Mellon, Ph.D. (2008) from Princeton Major grants: NIH R21CA299494 (cancer virome), U24HL175772 (HVP consortium), OT2CA297578 (early-onset colorectal cancer prevention) His work spans functional metagenomics , microbiome diagnostics , and structured biological knowledge in machine learning . Recent studies include strain-level microbiome mapping and microbiome links to depression, diabetes, and cardiovascular disease . He contributes to open-source tools like MaAsLin and WAAFLE , and leads the Human Microbiome Project sub-cohort for inflammatory bowel disease microbiome characterization.

Vijay Kumarمشاهده پروفایل

استادیار

• Tumor Immunology
• Immunotherapy
• Innate Immunity
• +۳ مورد دیگر

Vijay Kumar, PhD, serves as an Assistant Professor in the Department of Surgery at Morehouse School of Medicine, where he directs the Laboratory of Tumor Immunology and Immunotherapy. His research focuses on tumor immunology and immunotherapy with emphasis on innate immune mechanisms and the tumor microenvironment. His academic background includes: PhD in Immunology and Medical Microbiology from Panjab University MSc in Toxicology from Hamdard University BSc in Botany, Zoology, and Chemistry from DAV College Dr. Kumar's research centers on understanding immune dysregulation in cancer, particularly through Toll-like receptors and macrophage biology. His work explores how inflammation and immune homeostasis influence tumor progression, aiming to develop novel immunotherapeutic strategies. Recent editorial contributions demonstrate expertise in translating fundamental immunological concepts into clinical applications, with significant focus on methodological advances in immune protocols. His publication record (2017-2024) reveals consistent scholarly output in immunological mechanisms, showing evolution from foundational topics like sepsis and vaccines toward contemporary cancer immunology. Key trends include historical perspectives on immunological discoveries (e.g., 140 years of macrophage research, 30 years of Toll-like receptor studies) and methodological frameworks for immune homeostasis in tumor contexts. No scientific awards were mentioned in the provided documentation. Information regarding student advising, grant funding, or specific mentorship activities was not provided in the available text, though his faculty position implies involvement in academic supervision within the Department of Surgery. Dr. Kumar leads the Laboratory of Tumor Immunology and Immunotherapy, which investigates immune cell interactions within the tumor microenvironment. The lab's work integrates historical immunological perspectives with modern therapeutic approaches, focusing on restoring immune homeostasis as a strategy for cancer treatment.

Qibin Zhangمشاهده پروفایل

استاد

• Analytical Biochemistry
• Biological Mass Spectrometry
• Proteomics
• +۳ مورد دیگر

Qibin Zhang is a Professor of Chemistry and Co-Director of the Center for Translational Biomedical Research at the University of North Carolina at Greensboro (UNCG), where he leads the Zhang Research Group in the Department of Chemistry & Biochemistry within the College of Arts and Sciences. His laboratory develops cutting-edge mass spectrometry technologies for proteomics, lipidomics, and metabolomics with applications in disease biomarker discovery and clinical diagnostics. Dr. Zhang's primary research interests focus on developing more accurate, sensitive, and higher throughput measurement capabilities for biomolecules. His work centers on three main areas: Proteomics : Temporal plasma proteomics for Type 1 diabetes progression, cell-specific and spatial tissue proteomics, immunopeptidome analysis for novel T1D autoantigens, antimicrobial peptides, and glycated proteome in diabetic complications Lipidomics : Tissue-specific global lipidomics, high-resolution ozone-induced dissociation mass spectrometry, advanced analysis of glycosphingolipids, and lipid glycation in diabetes Metabolomics : Tryptophan catabolism, oxylipins and inflammation, fatty acid and energy metabolism, and chemical isotope labeling-based metabolomics Analysis of Dr. Zhang's recent publications (2022-2024) reveals a strong focus on translational biomedical applications, particularly in diabetes research and exercise physiology. His work demonstrates expertise in both method development (improved mass spectrometry techniques, data processing software) and biological applications (disease mechanisms, nutritional interventions). The research consistently bridges analytical chemistry with clinical applications, showing particular strength in spatial proteomics and lipidomics approaches. Dr. Zhang teaches advanced analytical chemistry courses including CHE 632/732 Advanced Analytical Chemistry, CHE 633/733 Bioanalytical Chemistry, and CHE 431/531 Instrumental Analysis. His laboratory is equipped with state-of-the-art instrumentation including Thermo QExactive HF, TSQ Quantiva, LTQ-Orbitrap with ETD, nano-LC and UPLC systems, and a Leco GC-TOF mass spectrometer. The Zhang Research Group currently includes four postdoctoral research fellows working across various aspects of proteomics, lipidomics, and metabolomics research.

Chengxue Helena Qinمشاهده پروفایل

پژوهشگر ارشد

• Translational Pharmacology
• Cardiovascular Disease
• GPCR Biology
• +۳ مورد دیگر

Dr Helena Qin is a Senior Research Fellow at Monash University's Monash Institute of Pharmaceutical Science (Drug Discovery Biology Theme) and holds adjunct roles at the Baker Heart and Diabetes Institute and the University of Melbourne. She leads the National Heart Foundation Future Fellow laboratory, focusing on developing novel therapies for cardiovascular diseases through translational pharmacology and GPCR biology. Educated at the University of Melbourne, she earned a B.Biomed, PhD in Pharmacology, and First Class Honours in Medicinal Chemistry. Her research emphasizes formyl peptide receptors (FPRs) and their role in inflammation resolution, with nearly 40 publications in top journals. Key achievements include identifying FPRs' therapeutic potential against cardiovascular diseases and pioneering biased agonist drug design. Awarded prestigious fellowships (National Heart Foundation, JDRF, Baker Institute), her work addresses UN SDG 3 (Good Health) and 9 (Industry/Innovation). Major grants include NHMRC, National Heart Foundation, and Diabetes Australia funding. She actively mentors students and leads projects on GPCR-targeted therapeutics and pro-resolving medicines for cardiovascular and diabetic vascular conditions.

• Inflammation
• Immunity
• Cardiovascular Disease
• +۵ مورد دیگر

Dr. Heather L. Wilson is a Senior Lecturer in Immunity & Cardiovascular Disease at the School of Medicine and Population Health, University of Sheffield. With a DPhil in Pharmacology from Oxford and postdoctoral experience in immune cell biology, she specializes in macrophage dysfunction in aging and inflammatory diseases. Research: her work explores how macrophage function declines with age, exacerbates atherosclerosis, and drives autoimmune responses in diseases like lupus. She investigates human primary blood cells and uses zebrafish models to study IL-1β mechanisms. Teaching: she leads the MBChB Phase 3a Student Selected Component, co-deploys the MSc Reproductive Medicine Social Aspects module, and trains PhD/MSc students in cardiovascular cell biology. Grants: BBSRC, MRC, British Heart Foundation, Horizon 2020 Marie Curie ITN, Vivensa Foundation Awards: RCUK Fellowship (2005-2010), Fellow of the Higher Education Academy

Ahmet Coskunمشاهده پروفایل

استادیار

• Spatial Biology
• Single Cell Biotechnology
• Spatial Omics
• +۹ مورد دیگر

Dr. Ahmet Coskun is an Assistant Professor of Biomedical Engineering at Georgia Institute of Technology and Emory University, where he holds the Bernie-Marcus Early-Career Professorship. He directs the Single Cell Biotechnology and Spatial Omics Laboratory, an interdisciplinary program focused on multiparameter imaging of single cells within their spatial context. His work bridges the fields of bioengineering, computational biology, and systems biology to address fundamental challenges in cancers, immunology, and pediatric diseases. Dr. Coskun received his PhD from the University of California, Los Angeles (UCLA) working with Aydogan Ozcan. He completed postdoctoral training at the California Institute of Technology with Long Cai and served as an Instructor at Stanford University with Garry Nolan. His educational background has provided him with a strong foundation in both engineering principles and biological systems. Dr. Coskun's research lies at the nexus of multiplex bioimaging, microfluidic biodynamics, and big data biocomputation. His laboratory pursues three main research thrusts: spatial genomics (using seqFISH and correlation FISH methods), spatial proteomics (using CODEX technology combined with super-resolution imaging), and spatial metabolomics (using computational and isotope barcoding approaches with MIBI). His team develops machine learning algorithms to analyze the resulting high-dimensional imaging datasets, creating image-based 'omic technologies to reveal the spatial nature of biological systems. Their work has significant implications for understanding therapeutic response variability and cellular organization in health and disease. NSF CAREER Award 2024 NIH R35 MIRA Award 2023 BMES-CMBE Rising Star Award 2023 American Lung Association Innovation Award 2022 Student Recognition of Excellence in Teaching: Class of 1934 CIOS Award NIH K25 Award Burroughs Wellcome Fund CASI Award Dr. Coskun leads an interdisciplinary research team comprising PhD students from Bioengineering, Electrical and Computer Engineering, Mechanical Engineering, and Biomedical Engineering programs. His lab has been supported by numerous federal and private grants, including funding from multiple NIH institutes (NIA, NIAID, NCI, NIDCR, OD, and ORIP), Wellcome LEAP, Burroughs Wellcome Fund, NSF CMaT, American Cancer Society IRG, Multi-cellular engineered living systems (M-CELS), and Regenerative Medicine Center. In addition to his research, Dr. Coskun leads outreach programs through BioCrowd Studio, which engages K12 and undergraduate students through interactive virtual media and distributed biokits. The Single Cell Biotechnology and Spatial Omics Laboratory is strategically positioned at the forefront of spatial biology research. The lab benefits from advanced technologies including super-resolution microscopy, imaging mass spectrometry, combinatorial molecular barcoding, and machine learning to enhance the information capacity of cellular data. The team's innovative approaches to spatial multi-omics profiling have positioned them as leaders in understanding cellular heterogeneity and organization within tissues.

• Pharmacology
• Chemotherapy
• Cytofluorimetry
• +۳ مورد دیگر

Sabrina Pacor is an Associate Professor in Applied Biology (BIO/13) at the University of Trieste , where she teaches Pharmacology in the Pharmacy LM and STB BSc programs. With over 30 years of research experience in experimental oncology and host defense peptides, she has made significant contributions to studying antimicrobial peptides (AMPs) and their interactions with bacterial membranes. Her research focuses on: Direct antimicrobial activity of AMPs against Gram-positive and Gram-negative bacteria Indirect immunomodulatory effects of host defense peptides Development of drug delivery systems using nanomaterials (carbon nanotubes, gold nanoparticles) Mechanistic studies of ruthenium-based antimetastatic drugs She leads extensive cytofluorimetry research using flow cytometry platforms, particularly for evaluating: Cytotoxicity (necrosis/apoptosis, proliferation index) Modulation of host biological responses (chemotaxis, phagocytosis, ROS production) Peptide-bacterial membrane interactions through fluorescent labeling Her recent work demonstrates trends in: Proline-rich antimicrobial peptides against ESKAPE pathogens Hybrid antibiotic design (peptide-aminoglycoside conjugates) Structure-activity relationships in membranolytic peptides Evolutionary insights into defensin and cathelicidin families Prof. Pacor has co-authored over 100 peer-reviewed publications and actively mentors students, having supervised: 70 experimental/thesis reviews for Pharmacy/CTF Master's students 20 Bachelor's degree theses

Ben Maozمشاهده پروفایل

استاد

• Biomedical Engineering
• Nanotechnology
• Neuroscience
• +۴ مورد دیگر

Prof. Ben Maoz is a Professor at the Department of Bio-Medical Engineering , The Iby and Aladar Fleischman Faculty of Engineering , Tel Aviv University . He directs the MaozLab, which pioneers interdisciplinary research in neuroengineering, microphysiological systems, and nanoscale therapeutic delivery. His lab integrates engineering principles with neuroscience to model human diseases and develop translational technologies. Research Focus Prof. Maoz's research spans: Organ-on-Chip Platforms : Developing modular microfluidic systems (e.g., neurovascular units, PNS-CNS models) for disease modeling and drug screening. Nanoneuroengineering : Designing brain-targeted nanocarriers (liposomes, dendriplexes) for siRNA and antibody delivery in neurodegenerative disorders like Parkinson's. Medical Devices : Creating implantable sensors, nanogenerators for sensory restoration, and tools for traumatic brain injury analysis. Cellular Mechanobiology : Investigating biomechanical forces in tissues using magnetoresponsive hydrogels and 3D cultures. Publication Trends His recent work (2023-2025) emphasizes: Advanced drug delivery systems for neurological applications (e.g., siRNA to neurons, alpha-synuclein-targeting antibodies). Innovative organ-on-chip platforms for studying cancer metastasis, viral entry, and neuro-immune interactions. Biomaterials and nanotechnologies addressing sensory restoration, cellular contractility, and super-resolution imaging. Laboratory & Collaborations The MaozLab employs microfabrication, molecular biology, and in vitro modeling to tackle challenges in brain health, with collaborations spanning oncology, virology, and gastroenterology.

James C. Loمشاهده پروفایل

دانشیار

• Cardiometabolic diseases
• Cardiovascular biology
• Adipose tissue function
• +۳ مورد دیگر

James C. Lo, M.D., Ph.D., is the Rohr Family Clinical Scholar and Associate Professor of Medicine at Weill Cornell Medical College . As a physician-scientist, he directs a basic research laboratory investigating the molecular basis of cardiometabolic diseases. 2023 : Rohr Family Clinical Scholar 2023 : Associate Professor of Medicine, Weill Cornell Medical College 2021 : Assistant Professor of Medicine, Weill Cornell Medical College Education: 2006 - M.D., University of Chicago Pritzker School of Medicine 2004 - Ph.D., University of Chicago 1998 - B.S., University of Chicago Dr. Lo's research focuses on molecular mechanisms of metabolic diseases with emphasis on: Cardiovascular biology in diabetes and obesity Adipose tissue function and thermogenesis Pancreatic islet physiology in metabolic stress Inter-organ communication networks Novel therapeutic targets for diabetes Cardiac complications in metabolic disorders Complement system in endocrine regulation His lab employs single-cell RNA-seq , genetic models , and multi-omics approaches to study: β cell subpopulations in diabetes Complement receptor signaling Adipose-liver-heart cross-talk Extracellular vesicle-mediated dysfunction Sex-dependent metabolic regulation Scientific Contributions: First to identify adipsin's role in β cell protection Discovered complement system's role in islet function Defined adipose tissue as SARS-CoV-2 target Elucidated mechanisms of obesity-induced arrhythmias Developed cross-species models of metabolic stress Research Funding: Currently holds 8 major grants as Principal Investigator or Key Personnel, including: $2.1M - NIH/NHLBI Mechanisms of Obesity-induced Atrial Fibrillation (2025-2028) $2.8M - NIH/NIDDK NAD+ Metabolism in β Cell Dysfunction (2025-2030) $1.5M - AHA Obesity-Driven Atrial Fibrillation (2024-2027) $1.2M - AHA Zebrafish Heart Regeneration (2023-2026) His laboratory team at the Belfer Research Building (New York, NY) includes post-doctoral fellows, Ph.D. students, medical students, and research technicians working in a collaborative environment.

• DNA Repair Mechanisms
• Cancer Biology
• Genome Stability
• +۳ مورد دیگر

J. Ross Chapman is a Professor of Genome Maintenance Biology at the University of Oxford, holding positions at the MRC Molecular Haematology Unit (part of the Radcliffe Department of Medicine) and the Wellcome Centre for Human Genetics. He is a Cancer Research UK (CRUK) Career Development Fellow, Lister Institute Research Fellow, and EMBO Young Investigator Programme member. His research focuses on DNA repair mechanisms, particularly the balance between accurate and mutagenic repair pathways in cancer and immune systems. Key affiliations include the Francis Crick Institute and previous roles at the University of Sussex and Gurdon Institute. Education and Career Path: Started as a Research Assistant at the MRC Genome Damage and Stability Centre (2002), earned his PhD in Steve Jackson’s lab (2006), and held postdoctoral roles at Simon Boulton’s lab (2010). Established his independent group at Oxford in 2013, becoming an Associate Professor in 2017 and moving to the MRC Unit in 2020. Research Interests: Investigates genetic recombination mechanisms, DNA double-strand break (DSB) repair pathways, and their roles in immune system development and cancer. Recent work explores how faulty repair mechanisms drive cancer and immune disorders, targeting vulnerabilities for therapies like PARP inhibitors. Publications: Recent studies include discoveries on Shieldin/CST complex roles in DNA repair, BLM-BRCA1 interactions, and chronic inflammation in leukemia. His work bridges basic biology with clinical applications, such as drug resistance mechanisms in BRCA-deficient cancers. Awards: CRUK CDF, Lister Fellowship, EMBO Young Investigator Programme membership, and recognition for contributions to DNA repair research. Lab Team: Includes postdoctoral researchers (e.g., Ashleigh King, My Khanh Pham), DPhil students, and technical staff. Collaborates on projects like PARP inhibitor efficacy and immune system DNA repair dynamics.

Ellis Patrickمشاهده پروفایل

دانشیار

• Bioinformatics
• Biomedical Data Science
• Statistical Bioinformatics
• +۶ مورد دیگر

Associate Professor Ellis Patrick is an applied statistician and bioinformatician affiliated with the University of Sydney's School of Mathematics and Statistics, the Westmead Institute for Medical Research, and the Sydney Precision Data Science Centre. His research focuses on developing bioinformatics tools to analyze high-dimensional biomedical data, with applications in disease treatment, precision medicine, and understanding molecular drivers of conditions like Alzheimer’s, MS, and cancer. He holds a PhD from the University of Sydney and postdoctoral experience at Harvard Medical School and The Broad Institute. Education: PhD in statistical bioinformatics from the University of Sydney. Postdoctoral training included joint appointments at Brigham and Women’s Hospital, Harvard Medical School, and The Broad Institute of MIT and Harvard. Research Interests: Specializes in statistical bioinformatics, spatial omics, and high-dimensional data analysis, with emphasis on translational research in infectious diseases, organ transplantation, cardiovascular disorders, neurodegeneration, and oncology. His work combines computational methods with clinical data to uncover disease mechanisms and improve therapeutic strategies. Grants & Collaborations: Recent grants include PrecisionGO (MRFF-funded), White matter lesion transcriptomics (National MS Society), and studies on coronary artery disease and graft failure prediction. Collaborates widely with medical researchers, leveraging interdisciplinary teams to tackle complex health challenges. Labs & Teams: Leads the Bioinformatics Cluster at the Sydney Precision Data Science Centre, integrating computational and experimental approaches to advance precision health initiatives.

David Munnمشاهده پروفایل

استاد

• Tumor Immunology
• Immune Suppression
• Cancer Immunotherapy
• +۹ مورد دیگر

David Munn is a Professor at the Medical College of Georgia at Augusta University, with joint appointments in the Department of Pediatrics: Hematology/Oncology, Georgia Cancer Center, Pathology, Medicine, Biochemistry and Molecular Biology, and Cellular Biology and Anatomy. He serves as Co-Director of the Pediatric Immunotherapy Program, leading translational research in tumor immunology and immune suppression. His research focuses on the molecular mechanisms tumors use to evade immune detection, particularly through the IDO and BTK pathways. Key areas include: Regulation of regulatory T cells (Tregs) and tolerogenic dendritic cells in the tumor microenvironment Development of small-molecule inhibitors targeting immune checkpoints Design and immune monitoring of clinical trials combining IDO inhibitors with chemotherapy and radiation First-in-children trials for pediatric brain tumors His recent publications highlight work on BTK-IDO-mTOR axis inhibition, IDO inhibitor trials in melanoma, and mechanisms of immunosuppression in glioblastoma and aging. His research is supported by the National Institutes of Health and charitable foundations. Scientific contributions and service include: Published in high-impact journals including Science Immunology , Nature Immunology , and Immunity Chair, GCC Internal Promotion and Tenure Advisory Committee (2020) Chair, GCC PRMC (Protocol Review and Monitoring Committee) (2020) Member, GCC Director Search Committee (2019) Reviewer for professional journals (since 2015) Dr. Munn mentors a research team including postdoctoral fellows and research associates, and leads the Munn Lab at the M. Bert Storey Research Building. His work bridges fundamental immunology and clinical application, advancing novel immunotherapies for both adult and pediatric cancers.