معرفی
Dr. Ahmet Coskun is an Assistant Professor of Biomedical Engineering at Georgia Institute of Technology and Emory University, where he holds the Bernie-Marcus Early-Career Professorship. He directs the Single Cell Biotechnology and Spatial Omics Laboratory, an interdisciplinary program focused on multiparameter imaging of single cells within their spatial context. His work bridges the fields of bioengineering, computational biology, and systems biology to address fundamental challenges in cancers, immunology, and pediatric diseases.
Dr. Coskun received his PhD from the University of California, Los Angeles (UCLA) working with Aydogan Ozcan. He completed postdoctoral training at the California Institute of Technology with Long Cai and served as an Instructor at Stanford University with Garry Nolan. His educational background has provided him with a strong foundation in both engineering principles and biological systems.
Dr. Coskun's research lies at the nexus of multiplex bioimaging, microfluidic biodynamics, and big data biocomputation. His laboratory pursues three main research thrusts: spatial genomics (using seqFISH and correlation FISH methods), spatial proteomics (using CODEX technology combined with super-resolution imaging), and spatial metabolomics (using computational and isotope barcoding approaches with MIBI). His team develops machine learning algorithms to analyze the resulting high-dimensional imaging datasets, creating image-based 'omic technologies to reveal the spatial nature of biological systems. Their work has significant implications for understanding therapeutic response variability and cellular organization in health and disease.
- NSF CAREER Award 2024
- NIH R35 MIRA Award 2023
- BMES-CMBE Rising Star Award 2023
- American Lung Association Innovation Award 2022
- Student Recognition of Excellence in Teaching: Class of 1934 CIOS Award
- NIH K25 Award
- Burroughs Wellcome Fund CASI Award
Dr. Coskun leads an interdisciplinary research team comprising PhD students from Bioengineering, Electrical and Computer Engineering, Mechanical Engineering, and Biomedical Engineering programs. His lab has been supported by numerous federal and private grants, including funding from multiple NIH institutes (NIA, NIAID, NCI, NIDCR, OD, and ORIP), Wellcome LEAP, Burroughs Wellcome Fund, NSF CMaT, American Cancer Society IRG, Multi-cellular engineered living systems (M-CELS), and Regenerative Medicine Center. In addition to his research, Dr. Coskun leads outreach programs through BioCrowd Studio, which engages K12 and undergraduate students through interactive virtual media and distributed biokits.
The Single Cell Biotechnology and Spatial Omics Laboratory is strategically positioned at the forefront of spatial biology research. The lab benefits from advanced technologies including super-resolution microscopy, imaging mass spectrometry, combinatorial molecular barcoding, and machine learning to enhance the information capacity of cellular data. The team's innovative approaches to spatial multi-omics profiling have positioned them as leaders in understanding cellular heterogeneity and organization within tissues.
