معرفی
Seung Ha Nam is an Assistant Professor in the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine, affiliated with the Graduate School of Medical Sciences. She leads the Nam Lab, which focuses on the genetic and non-genetic drivers of cancer through single-cell multi-omics technologies. Her research integrates genomics, transcriptomics, and cellular identity to study hematopoietic neoplasms and clonal evolution.
Her research interests lie at the intersection of cancer biology, genomics, and molecular pathology. She develops and applies single-cell multi-omics methods such as Genotyping of Transcriptomes to simultaneously profile somatic mutations and whole transcriptomes in thousands of single cells. Her work has revealed how somatic mutations alter hematopoietic stem cell differentiation and how cell identity modulates the effects of these mutations. Current projects include studying inflammation's role in clonal hematopoiesis, non-genetic modifiers of mutation effects, and cell fate decisions in blood cancers.
The trend in her research, though specific articles are not listed, centers on advancing single-cell technologies to unravel the complexity of cancer evolution, particularly in hematopoietic systems. Her work emphasizes multi-modal data integration to capture heritable dimensions of cancer cells—including genetic, transcriptomic, epigenetic, and spatial features.
She has received several prestigious scientific awards, including:
- American Society for Clinical Investigation Young Physician-Scientist Award (2021)
- Burroughs Wellcome Fund Career Awards for Medical Scientists (2020)
- NIH Director's Early Independence Award (2020)
- K08 Clinical Investigator Award, NHLBI (2020)
- Alpha Omega Alpha (2013)
- Howard Hughes Medical Institute-NIH Research Scholars Program (2011)
Dr. Nam mentors in a research-intensive environment and is supported by major grants such as the NIH K08 and the NIH Director's Early Independence Award, which enable her independent research program. She was trained as a physician-scientist with clinical fellowships in Hematopathology and Molecular Genetics Pathology, and she contributes to the molecular hematopathology service at Weill Cornell Medicine.
She leads the Nam Lab, a collaborative and diverse research team focused on making fundamental discoveries with translational impact in cancer. The lab is dedicated to understanding the determinants of genotype-to-phenotype relationships in blood cancers and fostering a compassionate, discovery-driven scientific community.
