معرفی
Qibin Zhang is a Professor of Chemistry and Co-Director of the Center for Translational Biomedical Research at the University of North Carolina at Greensboro (UNCG), where he leads the Zhang Research Group in the Department of Chemistry & Biochemistry within the College of Arts and Sciences. His laboratory develops cutting-edge mass spectrometry technologies for proteomics, lipidomics, and metabolomics with applications in disease biomarker discovery and clinical diagnostics.
Dr. Zhang's primary research interests focus on developing more accurate, sensitive, and higher throughput measurement capabilities for biomolecules. His work centers on three main areas:
- Proteomics: Temporal plasma proteomics for Type 1 diabetes progression, cell-specific and spatial tissue proteomics, immunopeptidome analysis for novel T1D autoantigens, antimicrobial peptides, and glycated proteome in diabetic complications
- Lipidomics: Tissue-specific global lipidomics, high-resolution ozone-induced dissociation mass spectrometry, advanced analysis of glycosphingolipids, and lipid glycation in diabetes
- Metabolomics: Tryptophan catabolism, oxylipins and inflammation, fatty acid and energy metabolism, and chemical isotope labeling-based metabolomics
Analysis of Dr. Zhang's recent publications (2022-2024) reveals a strong focus on translational biomedical applications, particularly in diabetes research and exercise physiology. His work demonstrates expertise in both method development (improved mass spectrometry techniques, data processing software) and biological applications (disease mechanisms, nutritional interventions). The research consistently bridges analytical chemistry with clinical applications, showing particular strength in spatial proteomics and lipidomics approaches.
Dr. Zhang teaches advanced analytical chemistry courses including CHE 632/732 Advanced Analytical Chemistry, CHE 633/733 Bioanalytical Chemistry, and CHE 431/531 Instrumental Analysis. His laboratory is equipped with state-of-the-art instrumentation including Thermo QExactive HF, TSQ Quantiva, LTQ-Orbitrap with ETD, nano-LC and UPLC systems, and a Leco GC-TOF mass spectrometer. The Zhang Research Group currently includes four postdoctoral research fellows working across various aspects of proteomics, lipidomics, and metabolomics research.
