جست‌وجوی استاد و پژوهشگر

Jason Steinمشاهده پروفایل

دانشیار

• Genetics of brain structure and development
• Neural progenitor cell models
• Computational biology
• +۳ مورد دیگر

Jason Stein, PhD, is an Associate Professor in the Department of Genetics at the University of North Carolina School of Medicine and a member of the UNC Neuroscience Center. His work focuses on uncovering how genetic variation impacts brain structure, development, and neuropsychiatric disease risk. Stein’s lab employs neural progenitor cell models, organoid systems, and computational approaches to study gene regulation during neurogenesis. He has received notable awards including the Yang Family Biomedical Scholars Award and NIH grants for projects exploring gene-environment interactions in Alzheimer’s disease and autism spectrum disorder. His research combines advanced imaging techniques like MRI and genomics to map genetic effects on brain phenotypes. Key contributions include identifying common genetic variants influencing brain functional networks and developing cortical organoid models to study autism-related brain overgrowth. Stein collaborates widely, leveraging interdisciplinary teams to address translational challenges in neurogenetics. Education: Doctorate in Genetics (PhD) Labs/Teams: Stein Lab (UNC School of Medicine) Grants & Funding: NIA U01 Grant for gene-environment modeling NIMH R01 for autism organoid studies NC Biotechnology Center Flash Grant for electrophysiological organoid devices Stein actively mentors graduate students and postdocs, emphasizing translational research. Recent work highlights include developing novel imaging platforms for organoid analysis and advancing ethical frameworks for organoid research involving human biospecimens.

Veronique Chotteauمشاهده پروفایل

استاد

• Bioprocess Engineering
• Biopharmaceutical Production
• Perfusion Technology
• +۳ مورد دیگر

Veronique Chotteau is a Professor and Principal Investigator of the Cell Technology group at KTH Royal Institute of Technology's Department of Industrial Biotechnology. She leads the VINNOVA Competence Centre for Advanced BioProduction (AdBIOPRO), focusing on continuous bioprocessing of mammalian cells for biopharmaceuticals, viral vectors, and therapeutic cells. Her research emphasizes perfusion technology, mathematical modeling (kinetic and metabolic flux analysis), and process optimization. Active in projects like 'Data-Limited Learning of Complex Dynamical Systems,' she explores AI-driven bioprocess control. She directs AdBIOPRO’s efforts in high-cell-density perfusion and continuous manufacturing. Her work integrates bioreactor design, process intensification, and novel separation technologies (e.g., magnetic beads). Teaching includes courses on animal cell culture, drug development, and systems analysis. Over 50 peer-reviewed publications span bioprocess modeling, metabolic engineering, and bioreactor optimization. Her lab develops tools like microfluidic cartridges and Raman-based analytics for real-time process monitoring. Key collaborations include Digital Futures (a KTH-Stockholm University-RISE initiative) and industry partners for translational bioprocess solutions. Her research addresses challenges in scalable production of complex biologics under data-limited conditions.

Ana Francisca Osório de Almeida Coelho e Silvaمشاهده پروفایل

پژوهشگر

• Chemical Engineering
• Biotechnology
• Biomaterials
• +۴ مورد دیگر

Ana Francisca Osório de Almeida Coelho e Silva is a Junior Researcher at the Department of Chemistry, University of Aveiro, Portugal. Her research focuses on chemical engineering, biotechnology, and green chemistry with emphasis on biomarker detection, biopharmaceutical purification, and environmental applications of ionic liquids. She holds a PhD in Chemical Engineering (2018) and has conducted postdoctoral work in Europe and Canada. Education: PhD in Chemical Engineering, University of Aveiro (2018) MSc in Biotechnology, University of Aveiro (2012) with a year abroad at La Sapienza University of Rome BSc in Biotechnology, University of Aveiro (2010) Research Interests: Development of ionic-liquid-based aqueous biphasic systems for biomarker detection and biopharmaceutical purification Enantioselective separation of chiral drugs using chiral ionic liquids Valorization of pharmaceutical waste via sustainable extraction methods Adsorption of cytostatic drugs from urine using supported ionic liquids Awards: Best PhD thesis in Chemical Engineering (Iberoamerican Congress, 2018) Advising & Grants: Current PhD students: Maria Inês Costa de Sousa and Maria Silvina Marques Mendes Principal Investigator of FCT-funded project PTSURVIVE (PTDC/EMD-TLM/3253/2020) Co-PI of mVACCIL (EXPL/BII-BTI/0731/2021) Recipient of Scientific Employment Stimulus grant CEECIND/03076/2018 Labs & Affiliations: Active in CICECO - Aveiro Institute of Materials, collaborating on projects like IgYPurTech (ERC) and IonCytDevice (POCI).

Brandon Greeneمشاهده پروفایل

استادیار

• Biomedical Sciences
• Biologically Inspired Chemistry & Physics
• Energy, Catalysis & Green Chemistry
• +۷ مورد دیگر

Brandon Greene is an Assistant Professor in the Department of Chemistry & Biochemistry at the University of California, Santa Barbara (UCSB), with a joint appointment in Biomaterials Science and Engineering (BMSE). He leads the Greene Lab, which focuses on understanding non-equilibrium redox reactions in biological systems, particularly in water. His research bridges chemistry, biology, and physics to address challenges in bioenergy, biogeochemistry, and human health. Dr. Greene holds a B.S. in Chemistry from Washington State University (2009) and a Ph.D. in Chemistry from Emory University (2015), where he studied bioinorganic cofactors and photocatalysis. He completed postdoctoral research at Harvard University and MIT, investigating ribonucleotide reductase mechanisms under Daniel G. Nocera and JoAnne Stubbe. His research emphasizes redox biology, including phosphorus redox cycling, electron bifurcation, and thiyl radical enzymes. The lab employs protein engineering, spectroscopy, electrochemistry, and structural analysis. Recent work includes developing phosphite quantitation assays and elucidating mechanisms of enzyme inhibition. The Greene Lab has trained numerous students, including graduate and undergraduate researchers, who have pursued careers in academia, industry, and medicine. Notable alumni include Clara Bailey (EPFL postdoc) and Juan Carlos Caceres (MIT postdoc). Dr. Greene teaches CHEM 259 (Bioenergetics) and actively mentors through grants and outreach programs.

• Plant Pathology
• Agricultural Science
• Mycology
• +۱۰ مورد دیگر

Timothy Miles is an Assistant Professor and Extension Specialist at Michigan State University (MSU), part of the Department of Plant, Soil and Microbial Sciences within the College of Agriculture & Natural Resources. His work focuses on diseases of hops, blueberries, grapes, and other berry crops, with expertise in mycology, genomics, pathogen detection, and molecular diagnostics. He holds a B.S. in Biology from Western Michigan University and a Ph.D. in Plant Pathology from MSU. Miles’ research integrates field studies and molecular tools to address crop disease challenges, particularly fungicide resistance and sustainable management practices. Education: B.S., Biology, Western Michigan University, 2005 Ph.D., Plant Pathology, Michigan State University, 2011 Research Interests: Miles investigates fungal pathogens affecting specialty crops, emphasizing molecular diagnostics for rapid pathogen identification and fungicide resistance monitoring. His work includes developing diagnostic assays for pathogens like Erysiphe necator (grape powdery mildew) and Pseudoperonospora humuli (hop downy mildew). He also explores host resistance mechanisms and the impact of fungicides on microbial communities in crops. Recent studies highlight the role of genomics in understanding pathogen population dynamics and resistance evolution. Advising & Grants: Miles mentors numerous graduate and undergraduate students, with over 30 co-authored publications involving student researchers. His work is supported by grants from Project GREEEN (Michigan Initiative for Sustainable Agriculture) and industry collaborations. He leads the Small Fruit and Hop Pathology program at MSU, providing extension services to growers on disease management strategies. Labs & Teams: Miles collaborates with the USDA-ARS Crop Improvement and Protection Research Unit and the MSU Plant Pathology Lab. His team develops field-ready diagnostic tools and integrates molecular data with agronomic practices to improve crop resilience.

Patricia Pietrantonioمشاهده پروفایل

استاد

• Insect Toxicology
• Insect Physiology
• Vector Biology
• +۳ مورد دیگر

Patricia V. Pietrantonio is a Professor in the Department of Entomology at Texas A&M University and Texas A&M AgriLife Research Fellow. Her research focuses on insect toxicology and physiology using biochemical, molecular, and cellular approaches, targeting arthropod control mechanisms with emphasis on G protein-coupled receptors. Research interests span: Novel targets for arthropod control G protein-coupled receptor pharmacology Insecticide resistance in disease vectors High-throughput screening of chemical libraries Physiology of invasive mosquitoes and ticks Publications primarily focus on molecular mechanisms of insecticide resistance, neuropeptide receptor characterization, and innovative control strategies for disease vectors, with recent work emphasizing tick kinin receptors and mosquito kdr mutations. Awards and service include: Texas A&M AgriLife Research Fellow President of the Acarological Society of America (2022) Editorial Board: Insect Biochemistry and Molecular Biology Editorial Board: Archives of Insect Biochemistry and Physiology Former Associate Editor of Pest Management Science Has graduated 9 PhD students, 3 M.S., 1 M.Ag. students, and trained 19 post-docs and 12 international visiting scientists. Current service includes TAMU senator (2023-2024) and Chair of Tenure and Promotion Committee. Leads the Pietrantonio Lab researching arthropod endocrinology and molecular toxicology, collaborating with national and international teams on vector control strategies.

• Integrated Pest Management
• Entomology
• Insect Physiology
• +۶ مورد دیگر

Caixing Xiong is an Assistant Research Scientist in the Department of Entomology at Texas A&M University, affiliated with the College of Agriculture & Life Sciences and Texas A&M AgriLife Research. Her research focuses on integrated pest management (IPM) strategies, particularly targeting agricultural pests through molecular and biological approaches. Education: B.S. in Agriculture, China Agricultural University M.S. in Entomology, Auburn University Ph.D. in Entomology, Texas A&M University Research Interests: Development of sustainable pest control methods using neuropeptide receptors and small molecules Functional analysis of tick and mosquito signaling pathways Optimization of crop protection through rhizobacteria and microbial interactions High-throughput screening of G protein-coupled receptors for novel ligands Advising & Grants: No formal advisees listed, but her work is supported by Texas A&M AgriLife Research initiatives focusing on vector biology and agricultural pest management. Labs/Teams: Part of the Department of Entomology research group at Texas A&M, collaborating with AgriLife’s pest management and molecular biology teams.

• Synthetic Biology
• Genetic Engineering
• Biomedical Engineering
• +۵ مورد دیگر

Elizabeth Gardner is an Assistant Research Professor in the Department of Bioengineering at Rice University. She leads the Genetic Design and Engineering Center (GDEC), focusing on scalable DNA assembly pipelines, robotic automation, and next-generation sequencing to develop plasmid libraries for applications in protein engineering, cellular reprogramming, and clinical research. The GDEC is supported by CPRIT funding and collaborates with the Texas Medical Center. Education: Ph.D. in Bioengineering, University of Texas at Austin (2022) B.Sc. in Bioengineering, Pennsylvania State University (2015) Research interests include synthetic biology, genetic engineering, and biomedical applications. Her work spans drug discovery, virology, and immunology, leveraging yeast-based biosensors and CRISPR technologies. Recent publications highlight advancements in cannabinoid receptor engineering, SARS-CoV-2 antibody research, and orthogonal gene expression systems. Advising and Funding: Recipient of CPRIT funding for the GDEC Collaborations with the Texas Medical Center Labs/Teams: Director of the Genetic Design and Engineering Center (GDEC), Rice University.

Joshua Pierceمشاهده پروفایل

استاد

• synthetic chemistry
• chemical biology
• drug discovery
• +۳ مورد دیگر

Joshua Pierce is the Howard J. Schaeffer Distinguished Professor of Chemistry and University Faculty Scholar at North Carolina State University (NC State), where he also serves as Executive Director of the Integrative Sciences Initiative. He leads the Pierce Group, focusing on synthetic chemistry approaches to chemical biology and drug discovery, particularly targeting natural products and their biological mechanisms. His research develops novel reactions to synthesize complex molecules, aiming to identify drug leads for combating bacterial resistance and biofilm formation. Education: B.S. (2003) and Ph.D. (2008) in Chemistry from the University of Pittsburgh. Research Interests: Synthetic organic chemistry, natural product synthesis, antimicrobial agents, drug delivery systems, and the design of heterocyclic scaffolds for therapeutic applications. His group employs innovative synthetic strategies to address challenges in chemical biology, including the development of compounds targeting Staphylococcus aureus biofilms and vancomycin resistance. Publications: Over 60 peer-reviewed articles, with recent work emphasizing biofilm inhibition, prodrug design, and enantioselective syntheses. His research frequently appears in journals like Journal of the American Chemical Society , ACS Medicinal Chemistry Letters , and Chemical Communications . Labs/Teams: Director of the Pierce Group within the Department of Chemistry, collaborating with NC State's Integrative Sciences Initiative to bridge chemistry with biomedical applications. Grants & Funding: Awards supporting his work on antimicrobial agents and drug delivery systems, though specific grants are not detailed in the provided texts.

Simon Youngمشاهده پروفایل

مدرس

• Molecular Biology
• Microbiology
• Parasitology
• +۷ مورد دیگر

Dr. Simon Young is an Associate Lecturer in Biochemistry/Molecular Biology and Virology/Microbiology at the School of Biology, University of St Andrews. His research focuses on lipid metabolism in parasites, particularly Trypanosoma brucei (the causative agent of Human African Sleeping Sickness), and drug discovery for neglected tropical diseases. He leads Wellcome Trust-funded projects targeting novel antiparasitic drug candidates. His work integrates molecular biology, microbiology, and parasitology to understand parasite survival mechanisms and develop therapeutic strategies. Research interests include the role of lipid metabolism in parasitic diseases, host-parasite interactions, and the development of combination therapies for antibiotic-resistant pathogens. Notable contributions include studies on adipose tissue as a reservoir for Trypanosoma brucei and investigations into β-lactam therapies for Pseudomonas aeruginosa infections. Dr. Young has collaborated with institutions like the University of Edinburgh on tsetse fly symbiont research and has authored over 15 peer-reviewed articles in journals such as Cell Host & Microbe and Molecular Microbiology . His research aligns with UN Sustainable Development Goal 3 (Good Health and Well-being) by addressing global health challenges through innovative drug discovery approaches.

• Chemical Biology
• Cancer Biology
• Signal Transduction
• +۱۰ مورد دیگر

Kevan Shokat is a Professor in the Department of Cellular and Molecular Pharmacology at the University of California San Francisco (UCSF), where he leads a research group focused on chemical biology, kinase signaling, and targeted cancer therapies. His work bridges pharmacology, biochemistry, and oncology, with a strong emphasis on developing novel inhibitors for previously 'undruggable' targets like KRAS. His research interests center on signal transduction pathways in cancer, particularly the roles of Ras, mTOR, and kinase networks. He pioneered chemical genetic approaches using analog-sensitive kinases to map substrate networks and identify drug targets. His lab investigates mechanisms of drug resistance, oncogenic signaling, and the development of covalent inhibitors for mutant KRAS variants (e.g., G12C, G12D). He also explores mTOR modulation in cancer and neurodegeneration, and has contributed significantly to understanding kinase regulation and proteome dynamics. His recent publications highlight a strong trend in targeting oncogenic GTPases, developing chemical probes for spatial signaling, and uncovering resistance mechanisms in kinase inhibitors. The work spans structural biology, chemical probe design, and systems-level proteomics, often in collaboration with clinical and translational teams. Dr. Shokat has received numerous scientific honors, though specific awards are not listed in the text. His editorial roles and high-impact publications suggest recognition as a leader in chemical biology. He advises numerous students and postdoctoral researchers, as evidenced by his extensive co-authorship network. His lab also secures significant research grants, particularly in cancer drug discovery and kinase biology, though specific grants are not detailed. His laboratory is part of the UCSF academic and research ecosystem, collaborating across departments and institutions to advance chemical biology and therapeutic development.

• Malaria
• Cancer
• Nanoparticles
• +۳ مورد دیگر

Magdalena Plebanski is an internationally-recognized Adjunct Professor in Immunology at Monash University's Alfred Hospital. Her research focuses on developing affordable vaccines and treatments for malaria, cancer, and allergic diseases using innovative nanoparticle technologies. She has pioneered synthetic non-inflammatory nanoparticles for vaccine applications and contributed to understanding cancer immunology through clinical trials in leukemia and ovarian cancer. Her career includes significant contributions from Oxford University and collaborations across multiple institutions. She leads >50 patents across 10 families, founding biotech companies. With over 150 peer-reviewed publications in top journals like Nature and Science , her work aligns with UN SDGs for health and innovation. Plebanski has secured grants from NHMRC and international bodies, leading projects like the TBV malaria vaccine and ovarian cancer immunity studies. Her research emphasizes translational medicine, diagnostics, and immunotherapy advancements. Key Projects: Multiplex Ovarian Cancer Diagnostic, TBV Malaria Vaccine, Immunity-Ovarian Cancer Link Awards: Not explicitly listed but implied by her international recognition and patent success Labs/Teams: Collaborates with multidisciplinary teams in nanotechnology, immunology, and oncology

Tu Nguyen-Dumontمشاهده پروفایل

دانشیار

• Genomics
• Bioinformatics
• Cancer
• +۵ مورد دیگر

Tu Nguyen-Dumont is an Associate Professor of Genomic Medicine and Bioinformatics and Head of Clinical Genomics at Monash University's School of Translational Medicine. She holds an honorary appointment in the Department of Clinical Pathology at The University of Melbourne and is a Victorian Cancer Agency Mid-career Research Fellow (2022-2026). Her work focuses on cancer susceptibility genomics, high-throughput sequencing, and translational bioinformatics, contributing to UN Sustainable Development Goals related to health and innovation. Education: PhD in Molecular Biology-Oncogenetics from Université Claude Bernard Lyon 1 (2010) Postdoctoral Fellowship at the Genetic Epidemiology Laboratory, University of Melbourne (2011) Research Interests: Her expertise spans cancer genomics, pharmacogenomics, and precision medicine. Current projects include leveraging genomic data for personalized clinical management and advancing public health genomics. She leads initiatives like the Clinical Genomics group, aiming to integrate genomic medicine into clinical care. Awards & Grants: Victorian Cancer Agency Mid-career Research Fellowship (2022-2026) NHMRC Synergy Grant (2022-2026) MRFF Genomics Health Futures Mission Grant (2021-2025) National Breast Cancer Foundation Career Development Fellowship (2017-2021) Labs & Collaborations: Her team collaborates on projects like population genomic screening for cancer prevention and precision immunotherapies for 'cold' cancers. The Clinical Genomics group works to translate genomic discoveries into clinical applications, emphasizing cancer genomics and pharmacogenomics.

Martin Viklundمشاهده پروفایل

استاد

• Acoustofluidics
• Ultrasound Technology
• Biophysics
• +۴ مورد دیگر

Martin Viklund is a Professor at the Division for Biophysics (SciLifeLab), Department of Applied Physics, KTH Royal Institute of Technology. He leads the Wiklund Lab, focusing on acoustofluidics—the application of ultrasound in lab-on-a-chip devices for cell manipulation and 3D tissue engineering. His research includes acoustic trapping, acoustophoresis, and microfluidic systems for biomedical applications. Education: Bachelor's in Engineering Physics, Lund Institute of Technology (1993–1998) PhD in Physics, KTH Royal Institute of Technology (1999–2004) Postdoc at Fraunhofer Institute for Biomedical Engineering, Berlin (2004–2005) Research Interests: Acoustofluidics, 3D cell culture, micro-tissue engineering, ultrasound-based cell manipulation, and biomedical device development. His work emphasizes non-invasive methods for cell handling and tumor modeling. Awards: 2008: Göran Gustavsson Foundation Young Researcher Award 2014: KTH Teacher of the Year 2017: STINT Fellow Grants & Administration: Program Director for Engineering Physics at KTH (2017–present) Head of the Division for Biophysics (2024–present) Recipient of grants from the Swedish Research Council, Wallenberg Foundation, and others totaling over 40 million SEK. Labs & Teams: The Wiklund Lab at SciLifeLab, Gamma-3, specializes in acoustic tools for biomedical research. Collaborations include institutions in Japan, the U.S., and Europe.

Richard Meekمشاهده پروفایل

پژوهشگر ارشد

• Eukaryotic Glycobiology
• Carbohydrate-active Enzymes
• Post-translational Modifications
• +۳ مورد دیگر

Dr. Richard Meek is a Senior Research Fellow at the University of Southampton, specializing in eukaryotic glycobiology and carbohydrate-processing enzymes. His work intersects structural enzymology with neurodegenerative disease research, focusing on post-translational modifications and cell signaling networks. Key affiliations include the Plants and Food Security group, Neuroscience Institute for Life Sciences , and the ChemLife Network . His research addresses the roles of glycosylation defects in diseases like Primary Familial Brain Calcification. Glycosylation and neurodegeneration : Investigates how defective carbohydrate-processing enzymes drive neurodegenerative disorders. Fundamental glycobiology : Explores enzyme mechanisms through chemical tools and structural analysis. Recent publications highlight advancements in O-GlcNAc transferase inhibition, cryo-EM enzyme structures, and macrocyclic peptide therapeutics. He supervises PhD students Jacob Willcox (SoCoBio) and Nicole Elise James (Biological Sciences), accepting applications for new advisees. Contact: R.W.Meek@soton.ac.uk