جستجوی استاد راهنمای دانشگاهی

• Synthetic Biology
• Molecular Biology
• Cell Biology
• +۳ مورد دیگر

Prof. Barbara Di Ventura is a Full Professor at the University of Freiburg's Faculty of Biology, specializing in synthetic biology and optogenetics. She leads the Molecular and Cellular Engineering group, now part of the Centre for Biological Signalling Studies (BIOSS) and the Excellence Cluster CIBSS. Her research integrates molecular biology, synthetic biology, and mathematical modeling to study spatiotemporal control in cells. She holds an ERC Consolidator Grant (2020) for developing cancer therapies using synthetic biology. Di Ventura is also active in academic leadership, serving on boards of the German Association for Synthetic Biology (GASB) and the European Synthetic Biology Society (EUSynBioS). Education: PhD in Molecular Biology from EMBL Heidelberg, postdoctoral studies at the ZMBH under Victor Sourjik, and a brief period as a visiting scientist at the Max Planck Institute in Marburg. Research focuses on optogenetic tools, bacterial systems (e.g., MinC-MinD complex in E. coli), and interdisciplinary approaches. She advises iGEM teams and has developed web servers like Int&in for protein engineering. Awards include the ERC grant and leadership roles in major synthetic biology initiatives. Grants and Projects: Current work includes the ERC-funded targeted cancer therapy project and collaboration in Engineered Living Materials (ELMs) portfolios. Her lab emphasizes precision control of biological processes using light and mathematical modeling.

Owen Rackhamمشاهده پروفایل

دانشیار

• Systems Biology
• Bioinformatics
• Cellular Reprogramming
• +۳ مورد دیگر

Dr. Owen Rackham is an Associate Professor in Systems Biology at the University of Southampton, jointly appointed since 2020. He holds a PhD in Complexity Sciences and previously served as an MRC Career Development Fellow at Imperial College London (2012–2015) and Senior Research Fellow at Duke-NUS Medical School (2015–2016). He co-founded Mogrify Ltd., a cell therapy spin-out company commercializing his computational tools for cell reprogramming. His research focuses on integrating computational approaches with experimental biology to understand cellular reprogramming and disease mechanisms. Key areas include: Cell fate control via computational modeling High-throughput sequencing analysis Data-driven drug discovery Current projects involve: AI-driven cell-type expansion (BBSRC-funded) Epigenetic mechanisms in early-life adversity Multidisciplinary spatial biology platforms He leads the Cell and Molecular Medicine theme at the Alan Turing Institute and has published extensively in top journals like Nature and Nature Machine Intelligence. His work has led to patent applications and licensing partnerships.

• Oral Pathology
• Biomechanics
• Finite Element Analysis
• +۳ مورد دیگر

Dr. Babak Sarrafpour is a Lecturer in the Discipline of Oral Surgery, Medicine and Diagnostics at the University of Sydney's Faculty of Medicine and Health. He holds a PhD from the University of Sydney (2013) and completed a postdoctoral fellowship in New York before returning to Sydney in 2016. His research focuses on mechanical stress in tooth development, oral pathology, and finite element analysis. He has pioneered studies on tooth eruption mechanisms, mandibular cyst expansion, and biomechanical modeling of dental structures. Education: PhD in Biomechanics, University of Sydney (2013) Postdoctoral Fellowship, New York, USA (2014–2015) His work integrates computational models (FEA) with experimental systems to explore bone remodeling, cyst formation, and the role of mechanical forces in oral diseases. He has developed innovative teaching methods, including eNotebooks and Smart Sparrow platforms for Clinico-Pathological Enquiry-Based Learning (CPEBL). Recent projects include studies on bacterial adhesion mechanics and oral submucosal fibrosis mechanisms. Key Awards: 2016 NSW Fresh Science Nominee 2009–2013 Faculty Scholarship for International Students, University of Sydney Dr. Sarrafpour collaborates widely, with grants from the Australian Dental Research Foundation and industry partners. His work has been featured in media for discoveries like the role of chewing forces in tooth eruption and AI-driven dental education tools.

Hugo Darrasمشاهده پروفایل

استادیار

• Ant Genetics
• Social Evolution
• Reproductive Systems
• +۵ مورد دیگر

Dr. Hugo Darras is an Assistant Professor at Johannes Gutenberg University Mainz since 2023, leading the Group Darras focused on genetic systems and social evolution in ants. Previously a Postdoctoral Researcher at the University of Lausanne (2017-2023), he earned his PhD from Université Libre de Bruxelles (2017) and MSc from AgroParisTech (2011). Research Group: Group Darras studies unusual reproductive strategies in ants Email: Not publicly listed Research Interests: Dr. Darras investigates transitions between genetic systems in ants, including social hybridogenesis , double-clonality , and male chimerism . His work integrates population genetics, genomics, and cytology to explore how haplodiploidy and social organization facilitate these systems. Article Trends: His recent publications highlight genetic mechanisms in invasive ant species, epigenetic regulation in sex determination, and genomic consequences of hybridogenetic reproduction. Key themes include reproductive anomalies, thermal adaptation, and lncRNA functions. Group Members: Current advisees include PhD students Chuanxin Yu and Ina Köhler (co-supervised with Martelli Lab), and Master’s students Lena Fröhlich, Emilia Maria Romero Pineda, and Teo Danja Llazo. Labs & Teams: Affiliated with the Institute of Organismic and Molecular Evolution at JGU Mainz, his lab collaborates internationally on ant genomics and reproduction.

Woochan Jangمشاهده پروفایل

دانشگاهی

• Neuroscience
• Stem Cell Biology
• Developmental Biology
• +۳ مورد دیگر

Woochan Jang is a Research Assistant Professor at Tufts University School of Medicine, affiliated with the Department of Developmental, Molecular and Chemical Biology. He holds a Ph.D. from the University of Missouri (1997) and has held academic appointments in the School of Medicine since 2007. His research focuses on olfactory stem cell biology, neural regeneration, and mechanisms of aging in sensory systems. Key areas include understanding stem cell activation, multipotency, and the regenerative capacity of olfactory tissues. His work explores how injury and aging affect neural stem cells, with a particular emphasis on transcriptional regulation (e.g., p63, Ascl1) and signaling pathways (e.g., Notch, retinoic acid). He investigates functional recovery in olfactory circuits after damage and the molecular basis of olfactory dysfunction in diseases like schizophrenia. Jang’s studies utilize in vitro models (neurospheres) and in vivo transplantation to assess stem cell behavior and engraftment potential. Grants: Multiple NIH grants (2009–2019) funded studies on age-related olfactory loss mechanisms and anatomical bases of olfactory dysfunction. Affiliations: Tufts University School of Medicine, Department of Developmental, Molecular and Chemical Biology; previously in Anatomy and Cellular Biology. Publications highlight his expertise in stem cell dynamics, neuroregeneration, and olfactory system biology, with notable contributions to understanding globose basal cells and reserve neural stem cell populations.

George Gamowمشاهده پروفایل

استاد

• Astrophysics
• Nuclear Physics
• Cosmology
• +۴ مورد دیگر

George Gamow was a renowned theoretical physicist and professor at George Washington University (1934–1956), known for pioneering work in astrophysics, cosmology, and genetics. He developed the Big Bang theory’s physical framework, contributed to nuclear physics, and explored the genetic code. His annual theoretical physics conferences brought top scientists like Bohr, Einstein, and Feynman to Washington. Education: Studied at Odessa's Novorossiya University and Leningrad University, with fellowships at Copenhagen and Cambridge. Escaped Soviet oppression via defection in 1933. Became a U.S. citizen in 1939. Research focused on stellar energy mechanisms, nucleosynthesis, cosmic background radiation prediction, and DNA-protein coding. His popular science books (e.g., One, Two, Three... Infinity ) inspired future scientists. Awards: 1956 Kalinga Prize (UNESCO) for science communication. Advised key students like Ralph Alpher (Big Bang nucleosynthesis) and Charles Critchfield (thermonuclear reactions). Collaborated with Edward Teller, Niels Bohr, and Francis Crick. Led research at Carnegie Institution, advised U.S. military, and later taught at University of Colorado (1956–1968). Left a legacy blending bold theoretical work with public science education.

• Chemical Biology
• Medicinal Chemistry
• Natural Products Chemistry
• +۲ مورد دیگر

Tim Moritz Weber serves as a Research Fellow at Vrije Universiteit Amsterdam's Faculty of Science, Department of Chemistry and Pharmaceutical Sciences, with dual affiliation to the Amsterdam Institute of Molecular and Life Sciences (AIMMS). His research integrates chemical synthesis with biological applications, focusing on developing novel therapeutic and agricultural compounds through interdisciplinary methodologies. His primary research interests encompass Chemical Biology, Medicinal Chemistry, Natural Products Chemistry, Synthetic Organic Chemistry, and Pharmaceutical Sciences. He specializes in creating bioactive molecules—including prodigiosin derivatives for anticancer applications and nematode-targeting agents—using chemoenzymatic synthesis, click chemistry, and biotinylation techniques. His work emphasizes overcoming drug resistance in cancer therapy and developing sustainable solutions for agricultural parasitology through combinatorial approaches with natural products. Analysis of his recent publications reveals a cohesive trajectory in molecular design and biological evaluation. His research consistently bridges synthetic organic chemistry with practical applications, particularly in engineering noncanonical amino acids for protein modification, optimizing biotin-based molecular probes, and enhancing prodiginine derivatives for dual anticancer and antiparasitic activity. Key innovations include water-soluble ligand design, late-stage functionalization strategies, and combinatorial treatments leveraging natural product synergies. Dr. Weber operates within AIMMS, VU Amsterdam's premier research institute for molecular and life sciences, which provides advanced infrastructure for collaborative work across chemistry, biology, and pharmacology. This environment supports his interdisciplinary projects involving multi-institutional teams focused on translating chemical innovations into biological solutions.

Patrick O’Donoghueمشاهده پروفایل

دانشیار

• Genetic Code Expansion
• Programmed Protein Modification
• Protein Modifications in Disease
• +۳ مورد دیگر

Patrick O’Donoghue is an Associate Professor of Chemistry and Biochemistry at the University of Western Ontario, holding the Canada Research Chair (Tier 2) in Chemical Biology. He leads research on proteome diversity and its role in cancer and neurodegeneration. His lab develops methods for programmed protein modification and investigates mistranslation in live cells. Key research areas include genetic code expansion, protein modification signaling, and neurodegenerative disease pathways linked to tRNA mutations. Education: PhD from University of Illinois at Urbana-Champaign; Postdoctoral Fellow at Yale University. Awards include NSF Biological Informatics Fellowship and PhRMA Foundation Informatics Fellowship. Teaching includes courses like Biochemistry/Chemistry 4415B and 9703. Recent publications focus on tRNA variants in disease, Akt1 phosphorylation mechanisms, and ubiquitin signaling in Parkinson’s disease. His lab’s innovations include fluorescent reporters for mistranslation detection and engineered tRNAs to study protein synthesis errors. Research highlights include uncovering links between tRNA mutations and neurodegenerative diseases, and developing tools for live-cell protein modification analysis.

• Bioinformatics
• Genomics
• Evolutionary Biology
• +۹ مورد دیگر

Lex Nederbragt is an Associate Professor at the University of Oslo , affiliated with the Faculty of Mathematics and Natural Sciences and the Centre for Ecological and Evolutionary Synthesis . His work bridges genomics , bioinformatics , and STEM education , focusing on integrating computational methods into bioscience teaching. Email: lex.nederbragt@ibv.uio.no Phone: +47 22844132 Room: 3404 Lex specializes in genomics , particularly teleost fish genetics , genome assembly , and bioinformatics tool development . His research explores evolutionary biology , including immune gene evolution , hybrid speciation , and horizontal gene transfer . He also advances computational education through active learning , reverse instructional design , and Software Carpentry . His recent publications address graph-based genome analysis , genomic repeat landscapes , and pedagogical strategies . He received the Olav Thon Foundation national award for excellence in teaching (2025) and was recognized as a Merittert Utdanner (2023). Co-developer of tools like NucBreak , NucDiff , and khmer . Key contributor to Atlantic cod and grayling genome projects.

Bernd Jaglaمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Single-cell RNAseq analysis
• Cytometry data analysis
• +۷ مورد دیگر

Bernd Jagla is a Bioinformatics Research Scientist at the Pasteur Institute in Paris, France, where he has been working since 2009. Currently affiliated with the Bioinformatics and Biostatistics Hub (C3BI) and the Biomarker Discovery Platform, he previously held positions at Columbia University and Memorial Sloan Kettering Cancer Center in New York City. His educational background includes a PhD in Bioinformatics from the Free University Berlin (1999), a Chemistry Diploma from Free University Berlin & Technical University Munich (1989-1995), and Computer Science studies at Free University Berlin (1990-1991). Jagla's research focuses on bioinformatics applications for high-throughput biological data. His expertise spans single-cell RNAseq analysis, cytometry data processing, function prediction from sequence data, image analysis, mass spectrometry data analysis, and workflow management systems. He has developed several bioinformatics tools including SCHNAPPs for single-cell RNAseq analysis, KNIME extensions for Next Generation Sequencing, and Clean-ngs for adapter removal in sequencing data. His work demonstrates a strong emphasis on data quality assurance and visualization methodologies. His scientific achievements include: caBIG™ Embodying the Vision Award (2007) DFG Fellowship of the Graduiertenkolleg (1997-1999) Jagla actively contributes to bioinformatics training programs at Pasteur Institute, including the Bioinformatics program for PhD students financed by the INCEPTION program. He collaborates across multiple research teams and platforms, providing critical bioinformatics support for cytometry, next-generation sequencing, and microarray data analysis. His work bridges computational methods with biological applications, particularly in immunology and infectious disease research. As a key member of the Bioinformatics and Biostatistics Hub, he supports the Human Immunology Center and contributes to technological developments in bioinformatics infrastructure at the institute, working closely with the Transcriptome and Epigenome platform and the Biomarker Discovery Platform.

• Genomics
• Microbiology
• Bioinformatics
• +۳ مورد دیگر

Valerie Polonais is a Researcher affiliated with the IUT Clermont Auvergne at Université Clermont Auvergne . Her research focuses on microbial genomics, particularly the study of microsporidian pathogens, with emphasis on genome annotation workflows, protein localization, and comparative genomics. She has contributed to understanding the genetic mechanisms of these obligate intracellular parasites through analysis of model organisms like Drosophila melanogaster. Key research themes include: Microbial genome sequencing and annotation Host-pathogen interactions at molecular level Evolutionary genomics of minimal eukaryotic organisms Development of bioinformatics tools for genomic analysis Her work bridges fundamental microbiology with computational approaches, addressing both basic science questions and potential applications in infectious disease research. Recent studies emphasize functional characterization of polar tube proteins and genomic features of parasitic microbes.

Małgorzata Adamczykمشاهده پروفایل

دانشیار

• Biotechnology
• Chemical Sciences
• Biophysics
• +۵ مورد دیگر

Małgorzata Adamczyk is an Associate Professor at the Chair of Drug and Cosmetics Biotechnology within the Faculty of Chemistry at Warsaw University of Technology. She holds a D.Sc. and has held academic roles since 2003, including postdoctoral research at the Institute of Biochemistry and Biophysics (Polish Academy of Sciences) and research positions at the University of Manchester and the Central Institute for Labour Protection. Her research focuses on systems biology, microbial genetics, and metabolic regulation, particularly exploring RNA polymerase III activity's role in cellular metabolism, plasmid stability mechanisms, and protein-DNA interactions. She leads the Systems Biology and Synthetic Biology Lab and has published over 40 peer-reviewed articles, contributing to fields like tRNA modifications, mitochondrial dysfunction, and antibiotic resistance. Her work integrates experimental and computational approaches, with notable achievements including 1 patent, 7 research projects, and international collaborations. Education includes a PhD in biochemistry and molecular biology from the Institute of Biochemistry and Biophysics (2003), an MBA in innovation strategy from UC Berkeley (2013), and a Master's in biotechnology from Warsaw University of Life Sciences (1997). She has supervised numerous theses and actively participates in academic activities such as editorial roles and conference organizing. Awards include a Scopus h-index of 12 and WoS h-index of 12, reflecting her impactful contributions to biotechnology and microbiology.

• Long non-coding RNA (lncRNA) research
• Lipid Metabolism
• Adipocyte Biology
• +۳ مورد دیگر

Alastair Kerr is a Senior Research Specialist and Group Leader at the Department of Medicine, Huddinge, Karolinska Institutet. His research focuses on elucidating how long noncoding RNAs (lncRNAs) regulate lipid metabolism and contribute to cardiometabolic disease in adipocytes. He leads the Long noncoding RNA in the adipocyte research group, which integrates human adipose tissue biopsies, population genetics, and advanced molecular tools like CRISPRi/a and his novel TROOPS method to study lncRNA functions. Education & Career PhD in Molecular Biology (University of Oxford, 2017) Postdoctoral studies at Karolinska Institutet (2017–present) Research Highlights He discovered the lncRNA ADIPINT, which modulates pyruvate carboxylase activity to regulate triglyceride synthesis. His lab investigates lncRNA roles in lipid droplet metabolism and develops methods like TROOPS for high-throughput lncRNA interactome analysis. Current work links genetic variants in lncRNAs to metabolic dysfunction. Awards & Funding Swedish Research Council grants Novo Nordisk Foundation support ERC Starting Grant (2024) Laboratory Team Jordi Mengual Martí (Research Assistant) Katharina Schormair (PhD Student) Bingran Xie (Postdoctoral Researcher) Opportunities Open positions for students and researchers; contact alastair.kerr@ki.se for inquiries.

Todd Lamitinaمشاهده پروفایل

دانشیار

• Stress Response Mechanisms
• Neurodegenerative Diseases
• C. elegans Genetics
• +۳ مورد دیگر

Dr. Todd Lamitina is an Associate Professor of Pediatrics and Cell Biology at the University of Pittsburgh. His research focuses on stress response pathways and neurodegenerative diseases using the model organism C. elegans . He holds a PhD in Cell and Molecular Biology from Emory University (2002). His lab is funded by the NIH and offers positions for postdocs, students, and technicians. Visit his lab’s website: Lamitina Lab . Education: PhD in Cell and Molecular Biology, Emory University, 2002 Research Interests: Dr. Lamitina’s work spans two main areas: the molecular genetics of osmotic stress responses and the development of C. elegans models for neurodegenerative diseases like Huntington’s and ALS. His lab has identified novel pathways, including roles for the extracellular matrix and O-GlcNAc transferase in stress responses, and has explored mechanisms of toxicity from repeat expansions in non-coding regions. These studies aim to uncover therapeutic targets for currently incurable diseases. Recent publications highlight his lab’s exploration of stress response pathways and neurodegenerative mechanisms. Key areas include the role of SPOP in C9orf72 toxicity, OGT’s role in hypertonic stress, and polyQ-independent toxicity from repeat expansions. These studies underscore the lab’s focus on translational research and conserved mechanisms across species. Advising and Funding: Dr. Lamitina’s lab is supported by NIH grants. Current opportunities are available for trainees across postdoc, student, and technician roles. Labs/Teams: The Lamitina Lab uses C. elegans models to study stress responses and neurodegenerative diseases. They collaborate on projects funded by the NIH and aim to translate findings into therapeutic strategies.

Lena Constantinمشاهده پروفایل

پژوهشگر ارشد

• Neuroscience
• Genetics
• Developmental Biology
• +۳ مورد دیگر

Dr. Lena Constantin is a Postdoctoral Research Fellow at The University of Queensland's Frazer Institute. Her research focuses on neurodevelopmental mechanisms, genetic regulation in cerebellar development, and plant genomics. She has contributed to studies on microRNA roles in autism spectrum disorder, zebrafish models of Fragile X syndrome, and genome assembly of citrus and macadamia species. Education: PhD in Molecular Biosciences (2011) from The University of Queensland's Institute for Molecular Bioscience. Research Themes: Combines molecular genetics with neuroscience to investigate developmental disorders. Recent work includes auditory processing in rodent autism models and methodological advancements in flow cytometry for plant genome analysis. Publications: Over 15 peer-reviewed articles across neuroscience, genetics, and plant science. Notable contributions include brain-wide auditory network studies and genome sequencing projects. Labs/Teams: Collaborates within the Frazer Institute's translational research framework, contributing to cross-disciplinary teams in genomics and neurobiology.