- Epigenetics
- Neurodevelopment
- Chromatin Remodeling
- +۳ مورد دیگر
Dr. Nathalie Berube is a Professor in the Department of Anatomy and Cell Biology at Western University, specializing as a Basic Scientist in Pediatrics. Her research focuses on epigenetic regulation of brain development, particularly through the study of chromatin remodeling complexes like ATRX. Her work employs mouse models to explore neuronal survival, differentiation, and the molecular basis of neurodevelopmental disorders such as autism and intellectual disability. Education: Dr. Berube holds a Ph.D., though specific details of her academic training are not provided in the text. Her professional affiliations include the Medical Sciences Building and the London, Ontario campus of Western University. She contributes to both basic science and translational research in pediatric neurobiology. Research Interests: Her studies emphasize the role of ATRX protein in chromatin structure, gene transcription, and DNA methylation. Key areas include neurodevelopmental deficits, glial cell biology, and the interplay between epigenetic regulation and cognitive disorders. Her work bridges molecular mechanisms with clinical implications, such as autism spectrum disorder and intellectual disability syndromes. Publications: Over 50 peer-reviewed articles span topics from chromatin accessibility to microglial function. Notable contributions include mouse model studies of ATRX deficiency and insights into epigenetic signatures of genetic disorders. Full publication lists are accessible via Google Scholar and PubMed. Grants and Advising: While specific grants or student advisees are not detailed, her research program likely involves collaborative grants given the complexity of her experimental systems. No awards are explicitly mentioned in the provided texts. Labs/Teams: Active in the Anatomy and Cell Biology department, her lab focuses on epigenetic mechanisms in neurodevelopment. Collaborations with pediatric and genetic research groups are implied through her work on syndromes like ATRX-related intellectual disability.













