جست‌وجوی استاد و پژوهشگر

Rosa Di Feliceمشاهده پروفایل

استاد

• Computational Biology
• Quantum Computing
• Nanoscience
• +۷ مورد دیگر

Rosa Di Felice is a Professor of Physics and Astronomy and Quantitative and Computational Biology at the University of Southern California. Her career spans prestigious roles at institutions including CNR-NANO Institute (Modena, Italy) and Xerox Palo Alto Research Laboratory. She specializes in computational methods bridging quantum physics and biology. PhD in Physics, University of Rome Tor Vergata (1992-1995) BSc/MSc in Physics, University of Rome Tor Vergata (Summa cum Laude, 1986-1992) Her research focuses on quantum computing for biological systems , DNA-based nanodevices , and protein-surface interactions . She has pioneered studies on charge transfer in DNA, CRISPR/Cas9 dynamics, and quantum nanomaterials using molecular dynamics and density functional theory. Recent publications highlight quantum algorithms for corrosion inhibition , electrostatics in CRISPR complexes , and topology-driven charge transport in G-quadruplexes . Her work integrates quantum computing , molecular modeling , and nano-bio interfaces . She contributes to scientific leadership as Associate Editor for European Physical Journal B and Scientific Reports , and has organized workshops on quantum computing and DNA nanotechnology.

Loren Williamsمشاهده پروفایل

استاد

• Biochemistry
• Origins of Life
• Ribosome Evolution
• +۳ مورد دیگر

Loren Williams is a Professor at the School of Chemistry and Biochemistry at Georgia Institute of Technology. He leads the Williams Lab, focusing on RNA/DNA folding, ribosome origins, and chemical evolution. He is Director of the NASA-funded Center for the Origins of Life (COOL) and former Director of the RiboEvo Center. Education : B.Sc. in Chemistry, University of Washington (1981) Ph.D. in Physical Chemistry, Duke University (1985) NIH Postdoctoral Fellow under Alex Rich, MIT Biology Department (1988-1992) Research Interests center on reconstructing ancient ribosomal structures through phylogeny, evolutionary theory, biophysics, and bioinformatics. He explores how sequence, covalent damage, anti-cancer drugs, and proteins modulate RNA/DNA folding. His work bridges early Earth environments with life’s emergence, emphasizing water’s role and metal ion interactions. Article Trends (2018-2025): Interdisciplinary focus on ribosome evolution (e.g., Asgard archaea, LUCA), prebiotic chemistry (depsipeptides, thioesters), and molecular interactions (RNA-metal, G-quadruplexes). Recurring themes include combinatorial chemical systems, evolutionary modeling, and astrobiological implications. Scientific Awards : NSF CAREER Award (1995-1998) Sigma Xi Best Paper (1997) Petit Institute "Above and Beyond" Awards (2012, 2021) Georgia Tech Faculty Mentor Awards (2013, 2022) AAAS and ISSOL Fellowships Vasser Woolley Instruction Award (2019) Advising & Grants : Mentored students like Chiaolong Hsiao (Sigma Xi Best Thesis 2009). Leads NASA-funded initiatives (COOL, PCE3) and explores SARS-CoV-2 testing kit design.

Pavel Janscakمشاهده پروفایل

استاد

• DNA Metabolism
• Genome Stability
• Molecular Biology
• +۴ مورد دیگر

Prof. Dr. Pavel Janscak is an Adjunct Professor at the University of Zurich , leading the Group Leader role at the Institute of Molecular Cancer Research . His work focuses on genomic instability and DNA repair mechanisms , particularly in the context of transcription-replication conflicts . Education M.Sc. in Biochemistry, Charles University, Prague (1987) Ph.D. in Molecular Biology, Institute of Microbiology, Academy of Sciences of the Czech Republic (1993) Habilitation in DNA Metabolism/Genome Stability, University of Zurich (2014) His research combines state-of-the-art molecular and cell biology with advanced microscopy techniques , focusing on the causes and consequences of transcription-replication conflicts and their role in cancer development . His publications reveal expertise in R-loop biology , helicasemediated DNA repair , and genotoxic stress responses . Scientific Awards : Welcome Trust Traveling Fellowship (1994) Collaborations include Prof. Massimo Lopes, Prof. Anne Müller, and Prof. Claus Storgaard Sørensen. His lab has mentored numerous PhD students and postdocs , including alumni like Dr. Radhakrishnan Kanagaraj and Dr. Javier Peña-Díaz.

Paolo Mediniمشاهده پروفایل

دانشیار

• Neuroscience
• Neurophysiology
• Neurobiology
• +۵ مورد دیگر

Paolo Medini is an Associate Professor at Umeå University, affiliated with the Department of Medical and Translational Biology and the Center for Transdisciplinary AI. His research focuses on cortical microcircuits, sensory processing, and brain recovery mechanisms. Neuroscience Neurophysiology Cortical Plasticity Optogenetics His lab investigates how sensory information is processed by distinct cell types in cortical circuits and how these circuits adapt after brain lesions or sensory deprivations. Research spans both adaptive and maladaptive plasticity, aiming to differentiate molecular mechanisms for targeted interventions. Recent publications highlight applications of all-optical interrogation strategies and multisensory integration in the neocortex. Paolo Medini's group employs advanced techniques such as in vivo patch clamp recordings, two-photon calcium imaging, and optogenetics. They use genetically modified strains to study cell-type-specific responses and circuit reorganization post-lesion. Their work is critical for developing therapies in neurodegenerative diseases and cortical repair. Environmental enrichment for brain recovery (Nature Neuroscience) Cortical microcircuit organization (Neuron) Post-stroke plasticity (Journal of Physiology)

• Biochemistry
• Molecular Biology
• Pharmacology
• +۷ مورد دیگر

Michael B. Jarstfer, PhD, is an Associate Professor at the University of North Carolina at Chapel Hill and a member of the UNC Lineberger Comprehensive Cancer Center . He is affiliated with the Eshelman School of Pharmacy , where his research focuses on the chemical basis and biochemical functions of cancer-related pathways . Research Interests : Enzyme function, ribonucleoprotein complex assemblage, telomere maintenance, telomerase mechanism, synthetic and physical organic chemistry, molecular biology, enzyme kinetics, and small-molecule design for anticancer therapy. Key Findings : His work reveals the A-form helix interaction in telomerase, rate-limiting steps in RNA-DNA unwinding, and template-dependent regulation of telomerase activity. Current Projects : Rational design of small molecules targeting telomerase assemblage and fidelity, aiming to induce telomere sequence alterations for apoptosis in cancer cells without relying on telomere erosion. Contact : Office phone 919-966-6422 , email jarstfer@unc.edu , lab at Beard Hall Room 326 . Research Trends : His publications (1994–2025) emphasize telomerase as a universal anticancer target, interdisciplinary methods (synthetic chemistry, structural biology), and educational innovations in pharmacy training.

• Medicinal Chemistry
• Drug Design
• Alzheimer's Disease Therapeutics
• +۳ مورد دیگر

Dr. Oscar Mauricio Bautista Aguilera is an Assistant Professor in the Department of Organic Chemistry and Inorganic Chemistry at the University of Alcalá. His research group, Design, interaction and synthesis of bioactive compounds , focuses on developing therapeutic agents for neurodegenerative diseases and cancer through molecular design and synthesis. Research interests include: Design of bioactive molecules using molecular modeling techniques Synthesis of carbohydrate/oligonucleotide conjugates for antitumor applications DNA/RNA interaction studies, particularly G-quadruplex DNA ligands Isolation and characterization of natural products (flavonoids, terpenes) Development of metallotherapeutic compounds He leads significant research projects including: CM/JIN/2019-017 : Optimization of contilisant for Alzheimer's treatment (€50,540; Community of Madrid) PID2019-105813RB-C22 : New contilisant analogues (€121,000; MICINN) His publications demonstrate consistent focus on multi-target inhibitors for Alzheimer's therapy, with recent work exploring ferulic acid derivatives, tacrine developments, and novel quinolinone/triazolopyridopyrimidine scaffolds.

• Medicinal Chemistry
• Molecular Modeling
• Bioactive Compound Synthesis
• +۴ مورد دیگر

Dr. Rafael Castillo Romero is an Assistant Professor and Deputy Director of the Department of Organic and Inorganic Chemistry at the University of Alcalá. His research group, 'Design, interaction and synthesis of bioactive compounds,' focuses on molecular modeling, drug design, and natural product characterization for therapeutic applications. Research Interests: His work spans medicinal chemistry, metallodrug synthesis, G-quadruplex DNA targeting, and nanoparticle-based drug delivery systems. Key areas include: Computational design of bioactive molecules Synthesis of carbohydrate/oligonucleotide conjugates for oncology Isolation of flavonoids/terpenes from natural sources Antibiofilm nanosystems using functionalized silica Publications & Innovation: Recent articles (2022-2023) emphasize nanotherapeutic platforms. Patent contributions include boron-based therapies (2020) and neuroblastoma-targeted ligands (2018). Teaching: Courses cover pharmaceutical chemistry, laboratory operations, and industrial chemistry across multiple degree programs.

Lucy A Godleyمشاهده پروفایل

استاد

• Cancer Genetics
• Hematology
• Oncology
• +۳ مورد دیگر

Lucy A Godley, MD, PhD, serves as the Jeffrey and Marianne Silver Family Professor of Oncology and Professor of Medicine in the Hematology and Oncology division at Northwestern University Feinberg School of Medicine. She is a physician-scientist actively affiliated with the Robert H. Lurie Comprehensive Cancer Center, where she conducts research and provides clinical care in hematologic malignancies. Educational background: BA: Harvard and Radcliffe Colleges (1988) PhD: University of California at San Francisco (1995) MD: Northwestern Feinberg School of Medicine (1997) Her research centers on the genetic architecture of blood cancers, with emphasis on germline variants in DDX41 and CHEK2 genes that drive hematopoietic malignancies. Through molecular biology and cancer genetics approaches, she investigates genome instability mechanisms, variant classification, and translation of findings into clinical risk assessment frameworks. Her work bridges laboratory discovery and patient care through implementation science initiatives. Analysis of recent publications reveals consistent focus on cancer genomics, particularly germline variant detection in tumor profiling and molecular mechanisms of genome integrity maintenance. Studies demonstrate how DDX41 resolves G-quadruplex structures to prevent cGAS-mediated cell death in erythroid cells, while CHEK2 variant research establishes new paradigms for leukemia predisposition syndromes. Scientific recognition includes: Nimmo Visiting Speaker, Royal Adelaide Hospital (2023) As a clinician-scientist, Dr. Godley leads translational research within the Lurie Cancer Center, mentoring trainees while developing clinical frameworks for genomic data integration. Her current initiatives address implementation challenges in bringing cancer genetics discoveries from bench to bedside, with emphasis on improving risk assessment and therapeutic strategies for blood cancer patients.

Rick Russellمشاهده پروفایل

استاد

• Biochemistry
• Molecular Biology
• Genetics
• +۳ مورد دیگر

Rick Russell is a Professor and Associate Chair for Graduate Education in the Department of Molecular Biosciences at the University of Texas at Austin's College of Natural Sciences. He holds the prestigious Lorene Morrow Kelley Endowed Faculty Fellowship. Department: Molecular Biosciences Program Affiliation: Interdisciplinary Life Sciences Graduate Programs Office: MBB Room 2.212 Russell's research focuses on structured nucleic acids (RNAs and DNAs) and the enzymes that interact with and manipulate these structures. His laboratory investigates several key areas including RNA folding mechanisms, RNA helicase function, CRISPR-Cas enzyme targeting mechanisms, and the stability and disruption of RNA and DNA G-quadruplex structures. His work bridges biochemistry, molecular biology, and genetics to understand fundamental cellular processes at the molecular level. Dr. Russell has established himself as a significant contributor to the field of nucleic acid biochemistry, with research that has implications for understanding gene regulation, cellular function, and potential therapeutic applications. His laboratory serves as a training ground for graduate students in the Interdisciplinary Life Sciences Graduate Programs. Biochemistry: Structural and functional analysis of nucleic acids Molecular Biology: RNA-protein interactions and enzymatic mechanisms Genetics: Implications of nucleic acid structure on genetic processes Rick Russell has received recognition through the Lorene Morrow Kelley Endowed Faculty Fellowship, which supports his research and educational mission at the university. As Associate Chair for Graduate Education, Dr. Russell plays a significant role in shaping the graduate curriculum and mentoring the next generation of molecular bioscientists. His leadership extends to the Interdisciplinary Life Sciences Graduate Programs, where he helps bridge traditional disciplinary boundaries to foster innovative research approaches.

Kavitha Sarmaمشاهده پروفایل

دانشیار

• Epigenetic Gene Regulation
• RNA Biology
• Chromatin Architecture
• +۶ مورد دیگر

Dr. Kavitha Sarma is an Associate Professor at The Wistar Institute, where she leads research in the Genome Regulation and Cell Signaling Program within the Ellen and Ronald Caplan Cancer Center. Her work focuses on epigenetic gene regulation mechanisms, particularly examining how RNA-mediated processes impact cellular function and disease development. Dr. Sarma earned her Ph.D. in biochemistry from Rutgers University Postdoctoral training at Massachusetts General Hospital-Harvard Medical School Her research centers on the mechanisms of RNA-mediated epigenetic gene regulation, with special emphasis on R-loops - triplex nucleic acid structures comprising DNA:RNA hybrids and displaced single-stranded DNA. She investigates how these structures form during transcription, particularly in G-rich repetitive regions where they can adopt G-quadruplex (G4) structures. Her lab explores the roles of R-loops in neuronal cancers and neurodegenerative diseases, developing innovative techniques like MapR for genome-wide identification of native R-loops without antibody dependence. Analysis of Dr. Sarma's publications reveals consistent focus on R-loop biology across nearly two decades, with recent work (2020-2025) increasingly examining the relationship between R-loops, G-quadruplex structures, and genome organization. Her research has evolved from foundational studies on chromatin modifiers to sophisticated investigations of how these nucleic acid structures influence CTCF binding, genome folding, and ultimately gene expression patterns in disease states. Dr. Sarma mentors graduate students and postdoctoral fellows in her laboratory, guiding research that bridges biochemistry, cell biology, and functional genomics. Her team employs approaches including biochemical assays, cell and molecular biology techniques, and genome-wide analyses using embryonic stem cell, neural stem cell, and cancer cell models. The Sarma Laboratory includes Postdoctoral Fellows: Michelle Lynskey, Shachin Dissanayaka Mudiyanselage, Phillip Wulfridge Graduate Students: Emanuel Forciniti, Kelvin Okpokpo Research Assistants: Kuo-Chen Fang Lab Technicians: Afrora Muca Her lab investigates how epigenetic alterations impact neuronal cancers and neurodegenerative diseases, with the goal of identifying new pathways that can be targeted to correct epigenetic perturbations.

Jacek Czubمشاهده پروفایل

استاد

• Molecular Dynamics
• Lipid Bilayers
• DNA Structures
• +۵ مورد دیگر

Professor Jacek Czub serves as both Head of the Department of Physical Chemistry and Professor at the Faculty of Chemistry, Gdańsk University of Technology. His academic career spans multiple research domains in computational biophysical chemistry with significant contributions to understanding biomolecular systems through advanced simulation techniques. Research Interests: Professor Czub's work centers on molecular dynamics simulations applied to complex biological systems. His research program investigates the structural and dynamic properties of lipid bilayers, DNA G-quadruplex structures, and antibiotic mechanisms—particularly focusing on amphotericin B's interactions with biomembranes. His methodological expertise includes free energy calculations and development of novel simulation approaches for studying macromolecular motions. Scientific Recognition: His research excellence has been recognized through several prestigious awards: Research subsidy within the Homing Plus program (Foundation for Polish Science - 2012) Scholarship for young, outstanding scientists (Ministry of Science and Higher Education - 2012) Postdoctoral scholarship from the Max Planck Society (2008) START program scholarship (Foundation for Polish Science - 2008) Professor Czub maintains active research collaborations, including membership in the Biophysical Society, and leads research projects investigating thermodynamic properties of solutions and physicochemical foundations of environmental analysis. His laboratory produces significant open research data, particularly on DNA G-quadruplex structures and molecular dynamics trajectories.

Subrahmanyam Sappatiمشاهده پروفایل

استادیار

• QM/MM
• Nuclear Quantum Effects
• AIMD
• +۷ مورد دیگر

Subrahmanyam Sappati is an Assistant Professor at the Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdańsk University of Technology. He earned his PhD in chemical sciences from IISER Pune in June 2019 and currently holds a prestigious Nobelium grant fellowship. Dr. Sappati's research focuses on computational approaches to understand molecular interactions at the quantum level. His primary methodologies include quantum mechanics/molecular mechanics (QM/MM) simulations, ab initio molecular dynamics (AIMD), and classical molecular dynamics (MD). His work spans multiple disciplines including nuclear quantum effects, proton transfer mechanisms, drug design, and photophysical properties of materials. Analysis of his publication record reveals a strong interdisciplinary trend, with recent work emphasizing applications in pharmaceutical development, particularly in antifungal and anticancer drug design, protein-ligand interactions, and materials science for energy applications. His research consistently combines computational modeling with experimental validation across diverse biological and chemical systems. Nobelium grant fellow Dr. Sappati actively contributes to the scientific community as a reviewer for multiple journals including ChemPhotoChem (since 2025), Bulletin of Materials Science (since 2023), and Physical Chemistry Research (since 2022). His research appears to be supported by various grants, with the Nobelium fellowship being explicitly mentioned. He is affiliated with the Computational Molecular Biophysics research group at the Faculty of Chemistry, where he leads computational studies of biomolecular systems, particularly focusing on hydrogen bonding networks, enzyme mechanisms, and drug-target interactions using advanced simulation techniques.

Jan Glinkoمشاهده پروفایل

مدرس

• Computer Vision
• Robotics
• Deep Learning
• +۷ مورد دیگر

Jan Glinko is an Assistant lecturer at the Department of Decision Systems and Robotics within the Faculty of Electronics Telecommunications and Informatics at Gdansk University of Technology. His academic work spans across multiple disciplines including robotics, computer vision, and molecular biology. His research interests focus on: Computer Vision and Deep Learning applications Robotics, particularly pick-and-place systems and autonomous manipulation Molecular dynamics and G-quadruplex topology analysis Synthetic dataset generation for deep learning model training Dr. Glinko's recent publications demonstrate a strong interdisciplinary approach, bridging the gap between robotics and molecular biology. His work on G-quadruplex topological landscape represents a significant contribution to understanding nucleic acid structures, while his robotics research focuses on practical applications of deep learning for autonomous systems. His scientific contributions include: Developing methods for training deep learning models using synthetic datasets Creating autonomous pick-and-place systems based on multiple 3D sensors Advancing the understanding of G-quadruplex topological landscape through large-scale conformational analysis At Gdansk University of Technology, Jan Glinko teaches various courses related to digital systems, programming fundamentals, and intelligent robotics. His teaching portfolio includes courses for Automatic Control, Cybernetics and Robotics programs, as well as supporting laboratory sessions for digital technology and logic systems.

Andrew Marshمشاهده پروفایل

دانشیار

• Supramolecular Chemistry
• Bioorganic Chemistry
• Chemical Biology
• +۴ مورد دیگر

Andrew Marsh is an Associate Professor at the University of Warwick, Department of Chemistry, focusing on multidisciplinary approaches to functional molecule synthesis and applications. His research bridges supramolecular chemistry, bioorganic chemistry, and medicinal chemistry, with an emphasis on non-covalent interactions and biological target engagement. Collaborations: Coventry University, University of Maryland, Bologna University Techniques: NMR, isothermal titration calorimetry, phage display His recent publications explore G-quartet hydrogels, antibiotic re-sensitization, and molecular self-assembly, with applications in pharmaceuticals and materials science. Teaching includes organic and physical organic chemistry, leading modules like CH271 Mechanistic and Biological Chemistry and CH3F5 Bioorganic Chemistry . Scientific awards include the Royal Society European Exchange Fellowship and EC Marie Curie (HCM) Fellowship . Supervision of M.Sc. and Ph.D. students is a key focus, with research funded through diverse grants.

Raymond Shivelyمشاهده پروفایل

استاد

• Synthetic Chemistry
• Organic Chemistry
• Inorganic Chemistry
• +۳ مورد دیگر

Raymond Shively serves as Professor of Chemistry at Baldwin Wallace University, where he has been a faculty member since 2006 after previously holding an associate professor position at Wilson College. His academic credentials include: Ph.D. in Chemistry from Case Western Reserve University B.S. in Chemistry from Case Western Reserve University Shively's research spans synthetic chemistry with active projects in organic, inorganic, and organometallic subfields. Current work involves developing less toxic ionic liquids for environmental applications, creating new organo-iron methodologies for polycyclic molecule synthesis, and collaborating with Dr. Diana Barko on metal complexes targeting DNA G-quadruplex structures for potential chemotherapeutic use. No scientific awards were documented in the source material. He mentors undergraduate researchers whose work has been presented at American Chemical Society meetings, with many alumni advancing to doctoral programs. While specific grant details are unreported, ongoing collaborative projects indicate active research funding. Shively directs a multidisciplinary research group integrating students into environmentally and medically focused chemical synthesis projects, emphasizing hands-on training in cutting-edge laboratory techniques.