جست‌وجوی استاد و پژوهشگر

Eddie Weitzbergمشاهده پروفایل

استاد

• Anesthesiology
• Pharmacology
• Physiology
• +۴ مورد دیگر

Eddie Weitzberg is a Professor in the Department of Physiology and Pharmacology at Karolinska Institutet. He specializes in anesthesiology, pharmacology, and physiology, with a focus on nitric oxide (NO) signaling, cardiovascular health, and metabolic disorders. His research explores the roles of dietary nitrate and nitrite in vascular function, blood pressure regulation, and tissue protection under hypoxic conditions. He is part of the Pharmacological nitric oxide research group led by Jon Lundberg. Research Interests: His work spans nitric oxide biochemistry, the interaction between diet and cardiovascular health, and the pathophysiological mechanisms underlying metabolic and cardiovascular diseases. Key areas include the nitrate-nitrite-NO pathway, microbiome interactions, and translational applications of NO signaling in clinical settings like coronary surgery and chronic diseases. Publications Trends: Recent articles highlight dietary interventions (e.g., Flexovital, nitrate supplementation), animal models of metabolic syndrome, and molecular mechanisms of NO in the vasculature. His work bridges basic science and clinical implications, such as cardioprotection in myocardial infarction and Alzheimer’s risk assessment. Grants & Funding: He has received grants from the Swedish Heart-Lung Foundation and the Swedish Research Council for projects in cardiovascular and metabolic research. Collaborations include studies on nitrate’s effects on longevity and cancer in rats, and clinical trials on nitrate in coronary surgery patients. Labs/Teams: He co-leads the Pharmacological nitric oxide research group with Jon Lundberg, focusing on innovative therapies and understanding NO’s role in health and disease.

Tharusha Jayasenaمشاهده پروفایل

پژوهشگر ارشد

• Neurodegenerative Diseases
• Alzheimer's Disease
• Biomarkers
• +۶ مورد دیگر

Dr. Tharusha Jayasena is a Research Fellow at the Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney. Her work focuses on neurodegenerative diseases, particularly Alzheimer’s, with an emphasis on dietary and molecular factors influencing brain health. She holds a PhD, MSc, and BSc from UNSW. Her research spans fatty acid metabolism, NAD+ pathways, and biomarker discovery, leveraging mass spectrometry and multi-omic techniques. She collaborates on large cohorts like the Sydney Memory and Ageing Study to investigate cognition-diet links. Education: PhD, MSc, BSc (UNSW Sydney) Key Projects: Fatty acids in neurodegeneration, NAD+ metabolomics Lab Affiliations: Proteomics Group, Brain Ageing Research Laboratory Publications highlight her work on glutamate in gliomas, psychedelics’ cognitive effects, and vascular dementia biomarkers. She advocates for translational research to bridge lab findings with clinical applications.

• Neuronal Circuits
• Epilepsy Mechanisms
• Dendritic Computation
• +۲ مورد دیگر

Professor Heinz Beck directs the Institute for Experimental Epileptology and Cognition Research at University of Bonn, where he investigates fundamental principles of neuronal circuit function and their disruption in epilepsy. Research integrates dendritic computation studies, in vivo imaging, and network analysis to understand cognitive processing mechanisms. Key publications demonstrate how degraded dendritic input detection underlies spatial memory deficits in epilepsy (Brain 2022) and establish astrocytic mediation of septohippocampal signaling (Neuron 2016). The laboratory employs multilevel approaches from single-neuron electrophysiology to system-level circuit analysis, developing conceptual frameworks for neural information processing. Current projects examine recurrent cortical motifs, dendritic integration properties in epileptogenesis, and neuromodulatory circuit regulation. As TRA Life and Health Speaker, he coordinates interdisciplinary neuroscience initiatives across Bonn's research community.

Sergei A. Grandoمشاهده پروفایل

استاد

• Immunology
• Molecular Biology
• Cellular Biology
• +۳ مورد دیگر

Sergei A. Grando is a Distinguished Professor of Dermatology at the University of California, Irvine (UCI) School of Medicine, where he serves as Director of the Immunobullous Clinic. His research focuses on the role of cholinergic signaling in immune cell function, particularly involving nicotinic acetylcholine receptors (nAChRs) and their effects on B-cell activation, apoptosis, and inflammation. His work bridges immunology, pharmacology, and cellular biology, with implications for autoimmune diseases and cancer biology. Grando's studies have examined the regulatory roles of nAChRs in B-cell differentiation markers (CD38, CD138), apoptosis pathways, and the interaction between nicotinic signaling and inflammatory markers like Cox-2. His research also extends to muscarinic acetylcholine receptors (mAChRs) in cervical cancer cells, linking cholinergic pathways to cellular motility and proliferation via ERK1/2 signaling. He has secured NIH grants (R01 DE014173, R21 ES014384) supporting investigations into the cholinergic system's impact on immune dysfunction and carcinogenesis. Grando collaborates extensively, with co-authors including Chernyavsky AI, Arredondo J, and others, and his work has been published in journals like International Journal of Immunopathology and Pharmacology and Journal of Neuroinflammation .

• Neuroscience
• Epilepsy Research
• Neuropharmacology
• +۳ مورد دیگر

Associate Professor Philip Ahring is a neuroscientist affiliated with the University of Sydney's Faculty of Medicine and Health, and a member of the Brain and Mind Centre. His research focuses on ion channel biology, particularly GABA-A receptors and nicotinic acetylcholine receptors, with emphasis on their roles in epilepsy, neurodevelopmental disorders, and neurological drug discovery. He has contributed to understanding genotype-phenotype relationships in epilepsy through functional analysis of genetic variants and has pioneered studies on receptor pharmacology and therapeutic modulation. Key research areas include: Mechanisms of GABAergic and cholinergic receptor dysfunction in neurological diseases Pharmacological characterization of receptor subunit variants Development of novel therapeutic strategies targeting ion channels Structure-function relationships in neurotransmitter receptors Recent work includes identifying pathogenic mechanisms in GABRB2, GABRD, and GABRA4 variants linked to epilepsy, and demonstrating therapeutic potential of compounds like vinpocetine for GABRA1-related disorders. He has secured grants including the 2024 FMH Rewarding Research Award and NHMRC grants for precision medicine initiatives. Collaborations span academic and industry partners, with notable contributions to drug discovery programs targeting nicotinic receptors and GABA-A subunit modulators. His lab's work bridges basic neuroscience with clinical translation, aiming to advance therapies for epilepsy and neurodegenerative conditions.

Catia Sterniniمشاهده پروفایل

استاد

• Neuroscience
• Gastroenterology
• Molecular Pharmacology
• +۳ مورد دیگر

Catia Sternini is a Professor in the Department of Medicine and Neurobiology at the University of California Los Angeles (UCLA). Her research focuses on the neurochemical and molecular mechanisms linking the enteric nervous system to gastrointestinal disorders, particularly in conditions like chronic intestinal pseudo-obstruction and Parkinson's disease-related constipation. Her work explores bitter taste receptors as sensors for gut luminal contents, opioid receptor dynamics in enteric neurons, and microbiota-dependent modulation of intestinal physiology. Recent studies highlight her contributions to understanding neurochemical profiles in porcine and human colon, and the role of epithelial barriers in neurodegenerative diseases. Publications span high-impact journals like Nature Reviews: Gastroenterology & Hepatology and Neurogastroenterology and Motility , addressing topics such as intestinal motility , neurotransmitter signaling , and neuroinflammation . Further details on her academic contributions are available through her UCLA profile and research database listings.

• E-cigarette toxicity
• Nicotine delivery systems
• Cardiovascular physiology
• +۴ مورد دیگر

Xuesi Shao, MD is a Clinical Professor in the Department of Internal Medicine at Charles R. Drew University of Medicine and Science. His research focuses on understanding the physiological and toxicological effects of nicotine and e-cigarette exposure, particularly on cardiovascular and respiratory systems. He has led NIH-funded studies developing aerosol exposure systems for rodent models and investigating transgenerational health impacts of vaping. Key research areas include: E-cigarette-induced cardiac dysfunction Nicotine pharmacokinetics in pregnancy Epigenetic programming from in utero toxin exposure Comparative toxicity of e-cigarette devices He has served as Co-Principal Investigator on multiple NIH grants (R42DA044788, R01HL135623) and published extensively in journals like Toxicology and Applied Pharmacology and Science Reports . His work emphasizes translational research linking molecular mechanisms to public health outcomes. Notable collaborations include studies with Theodore Friedman (electronic cigarette cardiovascular risk) and Amiya Sinha-Hikim (hepatic DNA damage mechanisms). His research networks focus on nicotine delivery systems and respiratory pharmacology.

• Neuroscience
• Neurodegenerative Diseases
• Neural Plasticity
• +۳ مورد دیگر

Ángela del Carmen Fontán Lozano is an Associate Professor in the Department of Physiology at the University of Seville. She leads the research group CTS-630 on Movement Disorders and is responsible for the project Palmitoilación en la Enfermedad Parkinson: Descubriendo Mecanismos y Biomarcadores . Her research focuses on neurodegenerative diseases, neural plasticity, and cellular mechanisms underlying learning and memory. She has contributed to over 30 peer-reviewed articles, including high-impact journals like PNAS and Neurobiology of Aging . Collaborates on projects exploring exercise-induced brain benefits and stem cell therapies. Directed doctoral thesis on intergenerational effects of exercise. Active in educational innovations using AI in physiology teaching. Key research areas: Alzheimer’s disease, Parkinson’s mechanisms, neuroinflammation, and epigenetic regulation. Leading projects on biomarker discovery and neural regeneration strategies. Team member in initiatives like Lesión y Regeneración and Estrategias Reparativas en el SNC . Recognized for work on DREAM protein’s role in cognition and aging. Holds a patent for a fibromyalgia animal model.

• Gene therapy
• Neurological surgery
• Parkinson's disease
• +۵ مورد دیگر

Michael G Kaplitt , M.D., Ph.D., is a leading Professor of Neurological Surgery at Weill Cornell Medical College , with additional appointments in Neurology, Otolaryngology-Head and Neck Surgery, and Neuroscience. He serves as the David and Ursel Barnes Professor in Minimally Invasive Surgery , focusing on surgical treatments for movement disorders like Parkinson's disease and essential tremor, particularly pioneering MR-guided focused ultrasound techniques. Education : Ph.D. in Molecular Neurobiology from The Rockefeller University (1993) M.D. from Weill Cornell Medical College (1995) B.A. in Molecular Biology and Russian Studies from Princeton University (1987) His research spans gene therapy for neurodegenerative diseases, molecular neurobiology , and neurosurgical innovations . Notably, he conducted the first FDA-approved gene therapy trial for Parkinson's Disease and continues investigating AAV vectors and focused ultrasound applications. Dr. Kaplitt has published over 40 papers and edited two books, including Gene Therapy of the Central Nervous System: From Bench to Bedside . His scientific awards include the Young Investigator Award from the American Society for Gene Therapy and Crain's 40 Under 40 recognition. He collaborates with institutions like MeiraGTx, LLC and Graviton Bioscience Corporation , holding proprietary interests in gene therapy technologies. His clinical expertise includes deep brain stimulation , spinal cord stimulators , and trigeminal neuralgia treatment.

Samuel Pappasمشاهده پروفایل

استادیار

• Neurodegeneration
• Movement Disorders
• Neurogenetics
• +۵ مورد دیگر

Dr. Samuel Pappas is an Assistant Professor at the Peter O’Donnell Jr. Brain Institute, UT Southwestern Medical Center. His work focuses on neurodegeneration, dystonia, and movement disorders using molecular, cellular, and behavioral approaches. Education Bachelor of Science in Physiology, Michigan State University Ph.D. in Physiology, Michigan State University Research Interests Dr. Pappas investigates mechanisms of selective neurodegeneration, cholinergic neuron dysfunction in dystonia, and novel therapeutic targets for movement disorders. His research combines animal models, molecular biology, and neuroanatomical techniques. Publication Trends His publications span dystonia, neurodegeneration, and neurogenetics, with a focus on animal models of disease, protein dysfunction (e.g., torsinA/B), and therapeutic interventions. Recent work includes functional connectivity studies and neurochemical analysis. Labs and Teams Dr. Pappas leads a team using animal and cell culture models to study dystonia and movement disorders, integrating molecular, cellular, and behavioral methods.

• Neuromechanics
• Neurological Rehabilitation
• Anterior Cruciate Ligament (ACL) Injury
• +۷ مورد دیگر

Nathan Schilaty, DC, PhD is an Associate Professor at the University of South Florida's Morsani College of Medicine, holding dual appointments in Neurosurgery, Brain and Spine and Medical Engineering. His research focuses on neuromechanical mechanisms of human movement, particularly in musculoskeletal disorders like neck/back pain, ACL injuries, and concussion. He integrates clinical trials, biomechanical experiments, and machine learning to advance evidence-based practices in chiropractic care and injury prevention. Education: Postdoctoral Certificate in Clinical & Translational Science (Mayo Clinic, 2019), PhD in Neuroscience (Brigham Young University, 2014), DC in Chiropractic Medicine (Parker University, 2007), and multiple BS degrees in Health Sciences and Chemistry (2003–2006). He also completed a BS in Anatomy from Parker University (2005). Research Interests: His work bridges clinical practice and scientific discovery, emphasizing biomechanical analysis of injury mechanisms, neuromuscular control in neurological disorders (e.g., multiple sclerosis), and AI-driven rehabilitation strategies. He collaborates on projects involving spinal biomechanics, sports injury prevention, and musculoskeletal modeling. Awards: Lincoln Endowed Chair (2021), Endowed Kelly Research Fellow (2016), and multiple academic scholarships. He is active in professional societies including the American College of Sports Medicine and International Society of Arthroscopy. Grants & Advising: While specific grant details aren't listed, his interdisciplinary research suggests involvement in biomechanics, neurology, and sports medicine funding. No listed students, but collaborates widely with peers like Timothy Hewett and Nicholas Bates. Labs: Leads studies in biomechanical testing, neuromuscular adaptation, and clinical outcomes analysis. His lab integrates advanced imaging, computational models, and clinical trials to develop novel therapeutic approaches.

Matthew R. Hodgesمشاهده پروفایل

استاد

• Respiratory Physiology
• Neurophysiology
• Genetics and Genomics
• +۳ مورد دیگر

Matthew R. Hodges is a Professor and Eminent Scholar in the Physiology Department at the Medical College of Wisconsin (MCW), serving as Director of Graduate Studies and Director of a NIH T32 Training Grant. His research focuses on neural control of breathing, Sudden Infant Death Syndrome (SIDS), and epilepsy-related respiratory dysfunction. He holds a PhD from MCW (2004) and a BA from Carleton College (1998). His lab employs advanced techniques like RNA sequencing and rodent models to study CO2 chemoreception and opioid effects. Education: PhD in Physiology, Medical College of Wisconsin, 2004 BA in Biology, Carleton College, 1998 Research Interests: Genetics/Genomics, Neurophysiology, Respiratory Physiology. Current projects include: Mechanisms of CO 2 sensing in brainstem neurons SIDS-related serotonin system abnormalities Seizure-induced cardiorespiratory failure (SUDEP) Opioid-induced respiratory depression Neuroplasticity in neonatal lung dysfunction Methodologies: Single-cell RNA sequencing Rodent models (rats, goats) Electrophysiology and microscopy Transcriptomics In vivo pharmacological interventions Awards: Parker B. Francis Fellow (2006-2009) Fellow of the American Physiological Society (FAPS) Advising & Grants: Mentor to 8 undergraduates, 2 medical students, and multiple PhD students. NIH-funded since 2009, with additional support from Children's Research Institute and Advancing Healthier Wisconsin Foundation. Collaborations include Universities of Missouri, Oregon, and MCW faculty across departments. Labs/Teams: The Hodges Lab emphasizes interdisciplinary training, studying breathing control in health/disease. Active projects involve epilepsy, opioid crisis mitigation, and neonatal respiratory adaptation. Collaborates with neurobiologists, neonatologists, and geneticists.

Gary Mouradianمشاهده پروفایل

استادیار

• Neural Control of Breathing
• Lung Biology
• Respiratory Diseases (COPD, BPD)
• +۵ مورد دیگر

Dr. Gary Mouradian is an Assistant Professor in the Department of Physiology at the Medical College of Wisconsin. He holds a PhD from MCW and completed postdoctoral training at the University of Colorado and MCW. His research focuses on the neural control of breathing in chronic lung diseases like COPD and BPD, with a particular emphasis on vagal sensory neurons and neuroepithelial bodies. He leads an interdisciplinary lab using techniques such as optogenetics, RNA sequencing, and transgenic mouse models. Education: BA in Biology from Carthage College (2009), PhD in Physiology from MCW (2014). Professional Affiliations: American Physiological Society (2011-present), American Thoracic Society (2014-present). Research Interests: Investigating how lung diseases disrupt neural breathing control via vagal fiber damage and neuroepithelial body dysfunction. Key areas include: 1) Vagal sensory neuron integrity in COPD/BPD, 2) Role of neuroepithelial bodies in respiratory modulation, 3) Molecular mechanisms underlying breathing dysfunction. Methodologies include patch-clamp electrophysiology and advanced imaging techniques. Recent work highlights the importance of oxidative stress in lung diseases and the use of transcriptomic approaches to identify immune response markers in cardiorespiratory nuclei. His lab actively recruits students and postdocs, emphasizing mentorship tailored to individual career goals. Awards: Parker B. Francis Award (2018), MCW Outstanding Medical Student Teacher (2022), Neuroscience Research Center Award (2023).

• Neuroscience
• Neurophysiology
• Systems Neuroscience
• +۳ مورد دیگر

Dr. Guanxiao Qi is a researcher at the Institute of Neuroscience and Medicine (INM) and the JARA Institute Brain structure-function relationships (INM-10) at the Research Center Jülich GmbH , Germany. His research focuses on understanding the structure, function, and neuromodulation of brain microcircuits, particularly in cortical layers 4, 6A, and 6B. He employs experimental techniques like paired patch-clamp recordings and computational modeling to study synaptic connectivity, neuromodulatory effects (e.g., acetylcholine, norepinephrine), and the dynamics of neuronal populations. Key areas of investigation include the role of FOXP2 in corticothalamic neurons, nicotinic receptor dysfunction in cortical layers, and the modulation of synaptic transmission by adenosine and cholinergic systems. His work bridges experimental data with algorithmic tools for network analysis, such as the Density visualization pipeline . Dr. Qi’s contributions span from basic neurophysiology to translational studies, addressing questions in systems neuroscience and computational biology. His recent publications (2022–2025) highlight advancements in layered microcircuit models, cell-type-specific neuromodulation, and the functional implications of synaptic plasticity. Collaborations within JARA and the Helmholtz Association position him at the forefront of integrative neuroscience research.

• Neuroscience
• Sleep Disorders
• Neurodegenerative Diseases
• +۳ مورد دیگر

Dr. Jean-François Gagnon is an Associate Professor in the Department of Psychiatry and Addictology at the University of Montreal's Faculty of Medicine . He holds the prestigious Canada Research Chair on Cognitive Decline in Pathological Aging . His research focuses on neurodegenerative diseases, particularly Parkinson's and dementia, with an emphasis on sleep-related biomarkers and clinical predictors. He has affiliations with leading research institutions, including the CRIUGM and CÉAMS Sleep Medicine Center . Education : He earned his Master’s in Neuropsychology from Université Laval and his PhD in Research and Intervention from UQAM. His postdoctoral training included studies at the Hôpital du Sacré-Cœur and the Institut universitaire de gériatrie de Montréal. Research Interests : His work explores the role of sleep disorders (e.g., REM sleep behavior disorder) as early markers of neurodegeneration. He investigates clinical and neuroimaging features of Parkinson’s and dementia, aiming to improve early diagnosis and understanding of disease progression. Grants & Projects : He leads and co-leads multiple funded projects, including studies on quantitative EEG markers of cholinergic neurodegeneration and the pathophysiology of REM sleep behavior disorder. Key funders include the Canadian Institutes of Health Research (CIHR) and the Weston Foundation. Advising : He has supervised numerous PhD and Master’s students focused on sleep, cognition, and neurodegenerative diseases. His research has contributed to identifying biomarkers and risk factors for Parkinsonism and dementia. Labs & Teams : He is affiliated with the Quebec Parkinson Network (RPQ) and collaborates with multidisciplinary teams studying aging and neurodegenerative disorders.