Samuel Pappas

Dr. Samuel Pappas is an Assistant Professor at the Peter O’Donnell Jr. Brain Institute, UT Southwestern Medical Center. His work focuses on neurodegeneration, dystonia, and movement disorders using molecular, cellular, and behavioral approaches.

Education

• Bachelor of Science in Physiology, Michigan State University
• Ph.D. in Physiology, Michigan State University

Research Interests

Dr. Pappas investigates mechanisms of selective neurodegeneration, cholinergic neuron dysfunction in dystonia, and novel therapeutic targets for movement disorders. His research combines animal models, molecular biology, and neuroanatomical techniques.

Publication Trends

His publications span dystonia, neurodegeneration, and neurogenetics, with a focus on animal models of disease, protein dysfunction (e.g., torsinA/B), and therapeutic interventions. Recent work includes functional connectivity studies and neurochemical analysis.

Labs and Teams

Dr. Pappas leads a team using animal and cell culture models to study dystonia and movement disorders, integrating molecular, cellular, and behavioral methods.