جست‌وجوی استاد و پژوهشگر

Uthayashanker Ezekielمشاهده پروفایل

استاد

• Cancer Biology
• Epigenetics
• Phytochemicals in Cancer Treatment
• +۳ مورد دیگر

Dr. Uthayashanker Ezekiel is a Tenured Professor in the Department of Clinical Health Sciences at Saint Louis University's Doisy College of Health Sciences. His research focuses on cancer biology, epigenetics, and stem cell applications in neurodevelopmental disorders. He holds a Ph.D. in Microbiology from Saint Louis University, with postdoctoral training at Yale University and the University of Chicago. Education: Ph.D. in Microbiology, Saint Louis University Post-Doctoral Fellowship, Yale University Post-Doctoral Fellowship, University of Chicago Master of Science in Integrated Biology, Madurai Kamaraj University Bachelor of Science in Zoology, Madurai Kamaraj University Research Interests: His laboratory investigates mechanisms distinguishing normal and cancer cells, emphasizing phytochemical anti-cancer activities, epigenetic modulation (e.g., miRNA, histone modifications), and metastasis suppression. Recent work includes developing induced pluripotent stem cell (iPSC) models for neurodevelopmental disorders like autism and epilepsy, focusing on neuronal differentiation and disease pathogenesis. Labs & Teams: Dr. Ezekiel leads a multidisciplinary team advancing iPSC-based disease modeling and cancer epigenetics. Current projects include iPSC-derived neuronal models for CTBP1-related disorders and phytochemical targeting of chemoresistant cancers.

Claire de la Covaمشاهده پروفایل

استادیار

• Cell Signaling
• Developmental Biology
• Molecular Genetics
• +۹ مورد دیگر

Claire de la Cova is an Assistant Professor in the Department of Biological Sciences at the University of Wisconsin-Milwaukee (UWM), within the College of Letters & Science. Her research focuses on cell communication and signal transduction pathways, particularly the Ras-MAP kinase cascade, using Caenorhabditis elegans and Drosophila as model systems. She investigates how these pathways regulate cellular processes like neuronal function, cell proliferation, and aging, with implications for cancer and developmental disorders. Education includes a BA in Biology from Macalester College (1999), a PhD in Genetics and Development from Columbia University (2008), and postdoctoral training at Columbia (2008–2018). She teaches courses such as BIO SCI 325: Genetics and BIO SCI 498G: Genetics of Development and Cancer . Her lab, accessible at https://sites.uwm.edu/delacova/ , employs genetic and quantitative imaging approaches to study novel regulators of Ras signaling. Key research areas include negative feedback mechanisms in signal transduction, roles of ubiquitin ligases in signal suppression, and the interplay between Myc-driven cell competition and tumor biology. Recent work highlights discoveries in ERK activity dynamics and the role of FBXW7 in substrate affinity modulation. Though no specific awards are listed, her contributions span over two decades with impactful publications in Developmental Cell , Science , and Cell Metabolism . Her work bridges molecular genetics, developmental biology, and cancer research, emphasizing evolutionary conservation and translational relevance to human diseases. Ongoing projects likely explore novel regulators identified in her lab and their applicability to oncogenic signaling pathways.

Yifan Yuanمشاهده پروفایل

استادیار

• Tissue Engineering
• Lung Vascular Biology
• Bioengineering
• +۳ مورد دیگر

Yifan Yuan, PhD, is an Assistant Professor in the Department of Anesthesiology at the University of Maryland School of Medicine. His research integrates molecular biology, bioengineering, and computational tools to study lung vascular microenvironments and develop native-mimicking models for disease and regenerative medicine. He completed his PhD at the University of Ottawa/Ottawa Hospital Research Institute and postdoctoral training at Yale University, focusing on lung and vessel engineering, single-cell RNA sequencing, and computational analysis. Education: PhD, Molecular Biology, University of Ottawa/Ottawa Hospital Research Institute, Canada Postdoctoral Associate, Yale University School of Medicine Research Interests: Lung vascular niche mechanisms and bioengineered models Single-cell analysis of cell-cell interactions Extracellular matrix regulation of vascular functions Translational applications in acute lung injury and drug discovery Grants & Awards: NIH K99/R00 Pathway to Independence Award (2022–2027): $995,506 UMB ICTR 2024 Pilot Grant: $50,000 American Heart Association Postdoctoral Fellowship (2020–2021) Labs & Collaborations: Yuan Lab at UMSOM focuses on vascularized lung tissue engineering and systems biology approaches. Collaborations with institutions like Yale University and Howard Hughes Medical Institute.

Myriam Chaumeilمشاهده پروفایل

استاد مدعو

• Metabolic Imaging
• Neurological Disorders
• Magnetic Resonance Spectroscopy (MRS)
• +۵ مورد دیگر

Myriam Chaumeil, PhD, is an Adjunct Professor at the University of California San Francisco (UCSF), affiliated with the Radiology and Biomedical Imaging Department. She holds advanced degrees including a PhD in Medical Physics from the University of Paris XI-Orsay and completed a postdoctoral fellowship in Radiology at UCSF. Her research focuses on metabolic imaging, particularly using hyperpolarized 13C MRI and MR spectroscopy to study neurological disorders such as multiple sclerosis, traumatic brain injury, Alzheimer’s disease, and brain tumors. Key interests include neuroinflammation, metabolic biomarkers, and translational diagnostic imaging techniques. Her clinical and research interests span metabolic imaging applications for neurodegenerative diseases, with a focus on developing non-invasive methods to assess cellular metabolism in vivo. Chaumeil’s work integrates preclinical models and clinical translation, emphasizing the use of advanced imaging modalities to study diseases like Huntington’s, aging-related pathologies, and cancer. She has contributed to consensus guidelines for hyperpolarized pyruvate MRI and pioneered techniques like deuterium metabolic imaging as alternatives to traditional PET scans. Research trends in her articles highlight innovations in metabolic imaging biomarkers, T-cell response tracking in autoimmune models, and cross-disciplinary insights linking neuroinflammation to adipose tissue biology. Her studies often involve cutting-edge MRI protocols and radiotracers such as [18F]F-AraG and hyperpolarized urea, advancing both diagnostic capabilities and mechanistic understanding of disease processes. Chaumeil’s work has been published in high-impact journals, with a focus on translating metabolic imaging advancements from preclinical to clinical settings. She collaborates on multi-center studies and actively contributes to advancing imaging standards in neurology and oncology.

Susanna Rosiمشاهده پروفایل

استاد مدعو

• Neuroinflammation
• Traumatic Brain Injury
• Therapeutic Cranial Irradiation and Cognition
• +۴ مورد دیگر

Susanna Rosi, PhD, is an Adjunct Professor at the University of California San Francisco (UCSF). She holds a BS (1995) and PhD (2000) in Biological Sciences from the University of Florence, Italy, followed by postdoctoral training in Pharmacology (2000–2001) and Psychology (2002–2006) at the University of Arizona. Her research focuses on neuroinflammation, traumatic brain injury, and the cognitive impacts of therapeutic irradiation and space radiation. Her work explores innate immune responses, synaptic plasticity, and mechanisms underlying memory deficits post-injury. Research Interests include: Neuroinflammation mechanisms, traumatic brain injury pathophysiology, radiation-induced cognitive decline, and microglia/macrophage dynamics. She investigates therapeutic strategies targeting inflammatory pathways and neuroprotective interventions for brain injury. Recent articles highlight her work on metabolic imaging in brain injury, neuroimmunology bottlenecks, and translational neurotrauma outcomes. Her studies often integrate preclinical models to address space radiation effects, stem cell therapies, and cognitive biomarkers. Advising and grants: No specific grants or advisee records are provided in the data. Collaborations likely involve interdisciplinary teams studying neuroscience and radiation biology.

James Balejaمشاهده پروفایل

دانشیار

• Metabolomics
• Protein Structure Analysis
• Nuclear Magnetic Resonance (NMR) Spectroscopy
• +۵ مورد دیگر

James Baleja is an Associate Professor in the Department of Medical Education at Tufts University School of Medicine. His research focuses on metabolomics and protein structure analysis using Nuclear Magnetic Resonance (NMR) spectroscopy, with emphasis on biomarker discovery for diseases like heart failure. He holds a PhD in Biochemistry from the University of Alberta and completed postdoctoral training at Harvard in protein dynamics. Dr. Baleja directs the Biochemistry Curriculum and teaches courses including 'Molecules to Cells' in the Medical School's Scientific Foundations of Medicine program. He co-leads biochemistry courses in the MS in Biomedical Sciences program and teaches dental and PhD students. His professional activities include roles with the Association of Biochemistry Educators and editorial boards of journals like the Journal of Biological Chemistry. His research has been funded by NIH and NSF grants, focusing on topics like peptide stapling, metabolic profiling in heart failure, and drug delivery systems. Key achievements include developing epidermal metabolite profiling methods and creating xenograft models for SDH-deficient tumors.

Michael C. Yuمشاهده پروفایل

دانشیار

• Protein Methylation
• RNA Processing
• Molecular Biology
• +۴ مورد دیگر

Michael C. Yu is an Associate Professor in the Department of Biological Sciences at the University at Buffalo (College of Arts and Sciences). His research focuses on the biological functions of protein arginine methylation, particularly its roles in pre-mRNA splicing, RNA Pol III transcription, and GPCR signaling. Yu holds a PhD from the University of California, Los Angeles, and completed postdoctoral research at Harvard Medical School. Education: PhD in Biological Sciences, University of California, Los Angeles Postdoctoral Research, Harvard Medical School Research Interests: Protein methylation’s impact on cellular processes, including splicing regulation, tRNA biogenesis, and GPCR signaling. His lab employs cell biology, biochemistry, proteomics, and genomics approaches to study these mechanisms in yeast and mammalian systems. Key Findings: Established methylation’s role in spliceosome assembly, revealed PRMT1’s regulation of tRNA transcription, and identified arginine methylation’s influence on dopamine receptor function. Recent work explores metabolic reprogramming in leukemia and phosphorylation-dependent mechanisms in neurodegenerative diseases. Grants & Awards: No awards explicitly listed in the provided texts, though his work has been highlighted in Faculty of 1000 and Nature Structural & Molecular Biology . Teaching: Teaches BIO 319, BIO 332, and BIO 404/504 courses. Office hours include dedicated student consultation slots. Labs & Collaborations: Collaborates with Denise Ferkey and Stewart Clark on GPCR projects, and uses model systems like C. elegans and budding yeast. His lab investigates methylation’s role in disease contexts such as cancer and Huntington’s disease.

Stelios T. Andreadisمشاهده پروفایل

استاد

• Stem Cell Bioengineering
• Vascular Tissue Engineering
• Regenerative Medicine
• +۶ مورد دیگر

Stelios T. Andreadis is a SUNY Distinguished Professor in the Department of Chemical and Biological Engineering at the University at Buffalo, State University of New York. He directs the Cell, Gene and Tissue Engineering Center and previously led the Stem Cells in Regenerative Medicine Training Program funded by NYSTEM. His research bridges fundamental molecular biology with translational biomedical engineering. Chemical Engineering PhD (University of Michigan, 1996) Mathematics MA (University of Michigan, 1996) Dr. Andreadis specializes in stem cell bioengineering , vascular/skin/gland tissue regeneration , and biomaterials design . His lab develops lentiviral arrays for pathway analysis in stem cell differentiation and pioneered cell-free vascular grafts commercialized through Angiograft, LLC. Current work focuses on metabolic reprogramming to reverse cellular senescence. His recent publications emphasize hydrogel-based delivery systems (11/15 recent papers) for applications in neural regeneration , vessel repair , and salivary gland restoration , often involving immune interactions and mitochondrial rejuvenation . Research spans from nanomaterial synthesis to preclinical animal models . Whitaker Foundation Young Investigator Award NSF CAREER Award SUNY Chancellor’s Award for Excellence AIMBE & BMES College Fellow With over $20M in NIH/NSF/NYSTEM funding since 1999, he has mentored 88+ researchers including 28 PhD students whose careers span Harvard/Stanford faculty , pharmaceutical leadership (Merck, Biogen), and academic institutions worldwide . His lab's innovations include self-healing vascular grafts and nanofiber scaffolds for Schwann cell differentiation.

Kiho Leeمشاهده پروفایل

دانشیار

• Gene Editing
• Animal Biotechnology
• Reproductive Biology
• +۳ مورد دیگر

Kiho Lee is an Associate Professor in the Division of Animal Sciences at the University of Missouri, part of the College of Agriculture, Food and Natural Resources (CAFNR). His research focuses on gene editing technologies, particularly in swine models, with applications in biomedical research, agricultural advancements, and disease modeling. Lee's work includes developing preclinical swine models for conditions like endometriosis and Alzheimer’s disease, as well as exploring CRISPR/Cas9 applications to study immunodeficiency and epigenetic reprogramming in livestock. His recent studies highlight advancements in precision editing, off-target analysis, and translational therapies using porcine systems. His publications emphasize innovations in oocyte maturation, embryo development, and the use of pigs as models for human disease. Lee collaborates on projects involving histotripsy for tumor targeting and xenotransplantation, reflecting a multidisciplinary approach to advancing both agricultural and biomedical science. While no specific awards or grants are listed here, his contributions to CRISPR-based gene editing and swine model development have positioned him as a key figure in the field of animal biotechnology.

Cameron McCarthyمشاهده پروفایل

استادیار

• Vascular Physiology
• Cardiovascular Diseases
• Metabolic Diseases
• +۳ مورد دیگر

Cameron McCarthy is an Assistant Professor in the Department of Cell Biology and Anatomy at the University of South Carolina School of Medicine. His research focuses on vascular physiology in cardiovascular and metabolic diseases, with particular emphasis on hypertension mechanisms, autophagy regulation, and energy sensing pathways. Dr. McCarthy co-leads the Cam Squared Labs with Dr. Wenceslau, studying mechanical and biochemical properties of microvascular tissue using mouse and rat models. His work examines dysregulation in cellular recycling processes and metabolic sensing in cardiovascular deterioration. His publications demonstrate consistent focus on vascular dysfunction mechanisms across multiple pathologies including hypertension, Alzheimer's, diabetes, and obesity. Recent articles explore novel pathways involving endothelial plasticity, cellular reprogramming, and specialized lipid mediators. Research is supported by the University of South Carolina School of Medicine and investigates therapeutic approaches targeting vascular-immune interactions and metabolic dysregulation.

Weiqun Pengمشاهده پروفایل

استاد

• Theoretical Biophysics
• Computational Biology
• Bioinformatics
• +۳ مورد دیگر

Dr. Weiqun Peng is a Professor of Physics and Graduate Advisor at the George Washington University's School of Engineering and Applied Science. He specializes in theoretical biophysics, computational biology, and systems biology, focusing on gene regulation mechanisms, particularly epigenetic processes that govern cell identity and disease. His work bridges physics-based modeling with biological systems, addressing questions about cellular differentiation and immune function. Education: Dr. Peng earned his Ph.D. in 2001 from the University of Illinois at Urbana-Champaign, specializing in statistical physics and soft condensed matter systems. He completed postdoctoral training at the University of California San Diego before joining GWU in 2004. Research Interests: Dr. Peng's research explores how epigenetic marks and regulatory proteins (e.g., 'writers,' 'erasers,' 'readers') shape gene expression in biological systems. His lab investigates the role of chromatin architecture, histone modifications, and transcription factors in processes like T cell differentiation, memory formation, and cancer progression. Key themes include the interplay between transcriptional regulation, genomic topology, and cellular identity. Scientific Contributions: His work has advanced understanding of epigenetic dysregulation in diseases such as cancer and autoimmune disorders. Notable findings include the role of Tcf1 and CTCF in CD8+ T cell memory, MLL3/MLL4 in embryonic stem cells, and intron retention in craniofacial development. Recent studies focus on chromatin dynamics during immune responses and the molecular basis of T cell exhaustion. Awards: While no explicit awards are listed, his prolific publication record and focus on high-impact biological systems reflect significant contributions to the field. Labs/Teams: Dr. Peng's research group integrates computational modeling with experimental approaches to study complex biological systems, emphasizing interdisciplinary collaboration between physics and biology.

Cam McCarthyمشاهده پروفایل

استادیار

• Cardiovascular Disease
• Metabolic Disorders
• Vascular Physiology
• +۵ مورد دیگر

Cam McCarthy is an Assistant Professor in the Department of Cardiovascular Translational Research Center Cell Biology and Anatomy at the University of South Carolina’s Molinaroli College of Engineering and Computing. He is also affiliated with the School of Medicine, Biomedical Engineering. His research focuses on vascular physiology in cardiovascular and metabolic diseases, particularly mechanisms of hypertension, autophagy dysregulation, and therapeutic interventions like exercise. McCarthy holds a Ph.D. in Physiology from the Medical College of Georgia, an M.S. in Exercise and Sports Science from the University of Memphis, and a B.S. in Physical Education from Appalachian State University. Research Interests: McCarthy’s lab investigates vascular deterioration in diseases such as hypertension and metabolic syndrome, emphasizing autophagy, energy sensing, and the role of innate immune cells (e.g., neutrophils). His work explores how interventions like caloric restriction and exercise can reverse vascular dysfunction. Recent studies include the impact of opioids on vascular aging, the role of beta-hydroxybutyrate in vasodilation, and the interplay between microbiota and blood pressure regulation. Awards and Honors: American Physiological Society (APS) Cardiovascular Section Clinical Science Young Investigator Award Fellow of the AHA (FAHA) Council on Hypertension NIH Pathway to Independence Award (K99/R00) American Heart Association Career Development Award (CDA) Labs and Teams: McCarthy co-leads the Cam Squared Labs (Laboratory of Vascular and Integrative Physiology) with Dr. Camilla F. Wenceslau, focusing on hypertension and vascular dysfunction mechanisms. The lab uses advanced techniques like myography, microscopy, and in vivo hemodynamics. Their work is supported by grants from NIH and AHA.

Wenbin Tanمشاهده پروفایل

دانشیار

• Congenital Vascular Malformations
• Vascular Biology
• Exosomal Biology
• +۵ مورد دیگر

Wenbin Tan is an Associate Professor in the Department of Cell Biology and Anatomy at the University of South Carolina School of Medicine Columbia. He is also affiliated with the Cardiovascular Research Center and the Department of Biomedical Engineering at USC. His research focuses on congenital vascular malformations, exosomal biology, and stem cell-based therapies. Key projects include developing iPSC-derived vascular models to study Port Wine Birthmark and Sturge-Weber syndrome, investigating endothelial dysfunction in hypertension, and exploring natural compounds for cardiovascular health. Dr. Tan’s work is supported by NIH, DoD, and ASLSM grants, including an NIH R01 (2018) and DoD Discovery Award (2018). Education: B.Sc./M.Sc. in Biochemistry (Central South University, China); Ph.D. in Neurophysiology (UCLA, 2008). Research Interests: Vascular malformations pathogenesis Exosome-mediated signaling Endothelial reprogramming for hypertension COVID-19 cardiovascular impacts His lab’s innovations include combining laser therapy with molecular strategies and leveraging exosomes for targeted treatments. Awards include the NIH/NIAMS K01 (2013) and recognition for translational research in vascular diseases.

Kari Lenhartمشاهده پروفایل

استادیار

• Stem Cell Biology
• Developmental Genetics
• Tissue Regeneration

Dr. Kari Lenhart is an Assistant Professor and Co-Director of the Graduate Biology Program in Drexel University's Biology Department. She holds a PhD from Princeton University and completed postdoctoral training at University of Pennsylvania. Her laboratory studies Drosophila testis stem cell systems to understand niche-stem cell interactions. Research explores how somatic cells regulate germline stem cell biology, tissue regeneration during stress, disruptions in tumorigenesis and aging, and comparative soma-germline dynamics between testes and ovaries. The lab employs genetic techniques and live imaging to investigate these mechanisms. Current projects examine somatic control of germline restoration, aging impacts on niche function, and sexual dimorphism in stem cell environments.

• Ovarian Cancer Biology
• Extracellular Matrix (ECM) Research
• Cancer Metastasis
• +۴ مورد دیگر

Marcin Iwanicki is an Assistant Professor in the Department of Chemistry and Chemical Biology at the Stevens Institute of Technology, affiliated with the Charles V. Schaefer, Jr. School of Engineering and Science. His research focuses on ovarian cancer metastasis, combining tissue engineering, live-cell microscopy, and CRISPR/Cas9 gene editing to study cell-ECM interactions and tumor progression. He also leads an interdisciplinary research group and serves on multiple institutional and national committees, including the National Cancer Institute study sections. Education PhD (2008), University of Virginia (Microbiology/Cancer Biology and Immunology) Postdoctoral Fellow (2008–2017), Harvard Medical School (Ovarian Cancer Metastasis) Research Interests Dr. Iwanicki investigates how cancer cells interact with extracellular matrices (ECM), amino acid osmolytes, and perfluorinated alkylated substances (PFAS). His lab explores mechanisms of cancer dissemination, including tumor-ECM dynamics, drug resistance, and metabolic reprogramming. Key projects include developing organoid-on-chip models for early cancer detection and studying taurine's tumor suppressive effects in ovarian cancer. Awards 2001-2006 Ruth Kirschstein Award (NCI) 2015 Ovarian Cancer Action HHMT Fellowship 2015 Marsha Rivkin Center Scholar-in-Training Award Grants & Service He leads grants from the NCI/NIH, Kaleidoscope of Hope, and industry partnerships. His service roles include peer review for Cancer Research , Cancers , and NIH/NCI panels. He also chairs the Stevens Facility for Animal Research Committee and advises pre-med students through clinical collaborations at Jersey City Medical Center. Labs & Teams The Iwanicki Lab at Stevens focuses on translational cancer research, integrating engineering tools with cell biology. The team includes high-school, undergraduate, and graduate students, with a mission to reduce ovarian cancer mortality through mechanistic insights and novel therapies.