معرفی
Claire de la Cova is an Assistant Professor in the Department of Biological Sciences at the University of Wisconsin-Milwaukee (UWM), within the College of Letters & Science. Her research focuses on cell communication and signal transduction pathways, particularly the Ras-MAP kinase cascade, using Caenorhabditis elegans and Drosophila as model systems. She investigates how these pathways regulate cellular processes like neuronal function, cell proliferation, and aging, with implications for cancer and developmental disorders.
Education includes a BA in Biology from Macalester College (1999), a PhD in Genetics and Development from Columbia University (2008), and postdoctoral training at Columbia (2008–2018). She teaches courses such as BIO SCI 325: Genetics and BIO SCI 498G: Genetics of Development and Cancer. Her lab, accessible at https://sites.uwm.edu/delacova/, employs genetic and quantitative imaging approaches to study novel regulators of Ras signaling.
Key research areas include negative feedback mechanisms in signal transduction, roles of ubiquitin ligases in signal suppression, and the interplay between Myc-driven cell competition and tumor biology. Recent work highlights discoveries in ERK activity dynamics and the role of FBXW7 in substrate affinity modulation. Though no specific awards are listed, her contributions span over two decades with impactful publications in Developmental Cell, Science, and Cell Metabolism.
Her work bridges molecular genetics, developmental biology, and cancer research, emphasizing evolutionary conservation and translational relevance to human diseases. Ongoing projects likely explore novel regulators identified in her lab and their applicability to oncogenic signaling pathways.
