جست‌وجوی استاد و پژوهشگر

• Ovarian Cancer Research
• Tumor Angiogenesis
• Reproductive Toxicology
• +۵ مورد دیگر

James Petrik is a Part-Time Professor in the Department of Obstetrics & Gynecology within the Faculty of Health Sciences at McMaster University. His academic career spans over three decades with continuous scholarly activity from 1989 through 2025, demonstrating sustained research productivity and engagement in his field. Dr. Petrik's research primarily focuses on ovarian cancer biology, with particular emphasis on tumor angiogenesis, the role of thrombospondin-1 in cancer progression, and the tumor microenvironment. His work explores how vascular normalization can enhance therapeutic effectiveness in ovarian cancer treatment. Additional significant research areas include reproductive toxicology, examining how substances like nicotine and cannabinoids affect reproductive function and fetal development, as well as investigating the developmental origins of health and disease. Analysis of his most recent publications (2023-2025) reveals a continued focus on ovarian cancer mechanisms, with increasing attention to tumor metabolism, cachexia, and the intersection between cancer and cardiovascular health (cardio-oncology). His work has evolved to incorporate advanced techniques including oncolytic viral therapy, molecular targeting strategies, and detailed characterization of tumor-immune interactions. The research demonstrates a strong translational focus, with many studies utilizing sophisticated mouse models to develop potential therapeutic approaches. Dr. Petrik maintains active collaborations across multiple disciplines, working with researchers in immunology, virology, metabolism, and cardiovascular science. His scholarly impact is evidenced by numerous publications, citations, and attention from news outlets and social media platforms as indicated in the profile metrics.

Ashok Kumarمشاهده پروفایل

استاد

• Skeletal Muscle Biology
• Cancer Cachexia
• Muscular Dystrophy
• +۳ مورد دیگر

Ashok Kumar is a Professor of Pharmacology and Else and Philip Hargrove Endowed Professor of Drug Discovery at the University of Houston College of Pharmacy , where he serves as Director of the Institute of Muscle Biology and Cachexia . His research focuses on molecular mechanisms regulating skeletal muscle mass and regeneration in pathological conditions. B.Sc. in Chemistry (Hons.), Rajdhani College, University of Delhi M.Sc. in Biotechnology, Banaras Hindu University M.Tech in Biochemical Engineering, IIT Delhi Ph.D. in Tumor Biology, University of Delhi Postdoc in Biochemistry, MD Anderson Cancer Center & Baylor College of Medicine M.S. in Computer Science, University of Houston Clear Lake Dr. Kumar investigates skeletal muscle signaling pathways related to Cancer cachexia and sepsis-induced atrophy TAK1/XBP1 axis in muscle regeneration Fn14 receptor mechanisms Satellite stem cell dynamics Therapeutic targets in muscular dystrophy His recent work explores ER stress, IRE1/XBP1 signaling, and NF-κB pathways in muscle homeostasis. Scientific contributions include 2012-2015: University Scholar, University of Louisville 2015-2019: Distinguished University Scholar, University of Louisville US Patent 9,751,950 (2017) - Anti-Fn14 antibodies US Patent App. 14/725,873 (2015) - TWEAK/Fn14 system Editorial roles in PLoS One , Cancers , and Frontiers in Physiology , with extensive peer-review experience.

Lisa Freemanمشاهده پروفایل

استاد

• Veterinary Nutrition
• Cardiovascular Disease in Animals
• Nutrition and Heart Disease
• +۳ مورد دیگر

Dr. Lisa Freeman is a Professor in the Department of Clinical Sciences at Tufts University's Cummings School of Veterinary Medicine and holds a secondary appointment at the Friedman School of Nutrition Science and Policy. She specializes in veterinary nutrition, particularly its role in managing heart disease in animals. Her research focuses on nutrition's impact on cardiovascular health and cachexia/sarcopenia. Dr. Freeman teaches across all four years of the veterinary curriculum and leads the Residents’ Enhanced Veterinary Education and Academic Learning (REVEAL) Program. She is a Board Certified Veterinary Nutritionist and earned her DVM and PhD from Tufts. Her work emphasizes evidence-based nutritional care for pets with heart conditions. Education: BS (Tufts, 1986), DVM (Cummings School, 1991), PhD in Nutrition (Friedman School, 1996) Certifications: Diplomate, American College of Veterinary Internal Medicine (Nutrition) Her teaching activities include courses on pharmacology, veterinary nutrition, and clinical excellence. She actively collaborates with the Clinical Nutrition Service and contributes to academic leadership through editorial roles in Seminars in Nuclear Medicine .

Barry Lairdمشاهده پروفایل

استاد

• Cancer Symptomatology
• Systemic Inflammatory Response in Cancer
• Cachexia
• +۳ مورد دیگر

Professor Barry Laird, affiliated with the University of Edinburgh's Institute of Genetics and Cancer , leads translational research in palliative medicine. His work focuses on the systemic inflammatory response in cancer patients and its role in symptoms like cachexia , fatigue, and pain. Clinically, he serves as a consultant in Palliative Medicine at the Edinburgh Cancer Centre and St Columba’s Hospice . Research Themes: Cancer symptomatology, inflammation-host interactions, nutritional support Collaborations: Prof Marie Fallon (Edinburgh), Prof Donald McMillan (Glasgow), Prof Anthony Chalmers (Glasgow), Dr Tora Solheim (Norwegian University of Science and Technology) Funding Sources: Marie Curie, Chief Scientists Office, Rising Tide Foundation, Pancreatic Cancer UK His evidence-based program spans basic science to clinical trials, aiming to improve prognostication and therapeutic efficacy in advanced cancer care. Current projects include anti-IL1 therapies ( MICA trial ), digital health solutions for nutrition, and palliative rehabilitation studies.

William E Mitchمشاهده پروفایل

استاد

• Protein Metabolism
• Chronic Kidney Disease (CKD)
• Muscle Atrophy
• +۵ مورد دیگر

William E Mitch, M.D. is a Professor in the Department of Medicine-Nephrology at Baylor College of Medicine. His career has focused on understanding and mitigating the metabolic complications of chronic kidney disease (CKD), particularly muscle wasting and insulin resistance. He holds appointments at Houston, TX-based clinical and research institutions, including the Baylor Clinic. Dr. Mitch's research integrates clinical practice with experimental studies to address protein metabolism dysregulation in catabolic states, such as CKD and cancer cachexia. Education: He completed medical training at Harvard Medical School (MD, 1967), followed by residencies and fellowships at Brigham and Women’s Hospital and Johns Hopkins Affiliate Hospitals, with advanced training at the National Cancer Institute. His certifications include Internal Medicine and Nephrology from the American Board of Internal Medicine. Research Interests: His work emphasizes mechanisms of muscle proteolysis in CKD, including roles of ubiquitin-proteasome system, caspase-3 activation, and signaling pathways like STAT3 and Notch. He explores therapeutic interventions targeting muscle atrophy, vascular complications (e.g., arteriovenous fistula failure), and metabolic cross-talk between muscle, kidney, and adipose tissues. Key Contributions: Pioneered studies linking CKD to insulin resistance, identified SIRPα as a mediator of CKD-induced cardiomyopathy, and developed dietary strategies to slow kidney disease progression. His research also addresses vascular calcification, fibrosis, and inflammatory pathways in CKD-associated cardiovascular disease. Professional Activities: Editorials, reviews, and leadership in the field, including the 2004 JASN Presidential Address. Active in translational research, with studies on therapeutic compounds targeting STAT3, myostatin, and Notch signaling pathways.

Nils Dahlströmمشاهده پروفایل

دانشیار

• Medical Imaging
• Quantitative MRI
• Low-Dose CT Techniques
• +۳ مورد دیگر

Nils Dahlström is an Associate Professor and Head of Unit at Linköping University's Department of Health, Medicine and Caring Sciences (HMV), within the Division of Diagnostics and Specialist Medicine (DISP). His primary affiliation is the Unit of Radiological Sciences, where he focuses on advancing medical imaging techniques and their clinical applications. He holds a Medical Degree from Uppsala University (1997), became a licensed medical practitioner (1998), specialized in Diagnostic Radiology (2003), and earned a PhD in Medical Radiology from Linköping University (2010). His research emphasizes hepatobiliary applications of quantitative contrast-enhanced MRI for assessing liver diseases, including chronic liver monitoring and pre-operative liver function evaluation. He also investigates low-dose CT imaging techniques and dual-energy CT applications. Additional interests include medical visualization technologies, such as 3D volume rendering on the Sectra platform, and educational strategies in medical imaging. He has contributed to projects like the ACCESS-ESLD study and EPSONIP study, addressing liver disease surveillance and NAFLD prevalence in primary care. Dr. Dahlström’s work bridges clinical practice and research, aiming to improve diagnostic accuracy and patient outcomes through innovative imaging methods. His interdisciplinary approach includes collaborations in computational modeling, radiation safety, and medical education. He actively participates in initiatives like the Center for Medical Image Science and Visualization (CMIV), fostering advancements in image analysis and visualization for healthcare.

Aldrin V. Gomesمشاهده پروفایل

استاد

• Cardiovascular Toxicology
• Oxidative Stress Mechanisms
• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) Effects
• +۴ مورد دیگر

Aldrin V. Gomes is a Professor and Vice Chair of Undergraduate Curriculum in the Department of Neurobiology, Physiology and Behavior at the University of California, Davis. His research focuses on cardiovascular and muscle physiology with an emphasis on oxidative stress mechanisms, NSAID-induced toxicity, and proteasome dysfunction in cardiac and skeletal muscle cells. He has authored numerous studies on the effects of environmental toxins, pharmaceuticals, and dietary interventions on cellular proteostasis and mitochondrial function. Key research areas include: (1) Cardiotoxic effects of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and diclofenac, (2) Oxidative stress pathways triggered by herbicides and acetaminophen, (3) Molecular mechanisms of muscle dysfunction in myopathies, (4) Gender-specific responses to pharmacological agents, and (5) Development of standardized protocols for antibody validation in proteomics research. Recent work has explored synergistic therapies for cancer-associated cachexia, telemedicine applications in urological follow-up, and epigenetic regulation in aging vasculature. His lab maintains a strong focus on translational research with implications for cardiovascular health, neurodegenerative diseases, and environmental health policy.

• Medical Epigenetics and Epigenomics
• Endocrinology and Diabetes
• Immunology in the medical area
• +۳ مورد دیگر

Eckardt Treuter is a Professor at Karolinska Institutet, leading the research group 'Epigenetic mechanisms underlying metabolic-inflammatory diseases' in the Department of Medicine, Huddinge. His work focuses on understanding how epigenetic alterations drive metabolic and inflammatory diseases, including obesity, type 2 diabetes, atherosclerosis, and fatty liver disease. He completed his PhD at Martin Luther University Halle-Wittenberg and conducted postdoctoral research at Karolinska Institutet, identifying nuclear receptor-associated proteins. Research interests include corepressor complexes (e.g., GPS2, HDAC3, NCOR/SMRT) and their roles in metabolic-inflammatory pathways. His team uses molecular biology, genomics, and genetically modified models to explore epigenetic reprogramming and therapeutic targeting strategies. Key projects involve studying GPS2's role in macrophage activation, atherosclerosis progression, and epigenetic memory between cell types. Recent work highlights GPS2's clinical relevance in systemic inflammation and diabetic risk in obese humans. Grants include funding from the Swedish Research Council and Novo Nordisk Foundation. Education: PhD in Molecular Biology (Martin Luther University Halle-Wittenberg), Postdoc at Karolinska Institutet Awards: Multiple grants for research on metabolic-inflammatory diseases Labs/Teams: Leads a multidisciplinary group with collaborations across clinical and basic science domains. Current students include PhD candidates Astradeni Efthymiadou, Sviatlana Sukhanava, and Yue Zhu.

Clint Allredمشاهده پروفایل

استاد

• Cancer Biology
• Nutrition
• Microbiome Studies
• +۳ مورد دیگر

Clint Allred is the Lake Simpson Dickson Distinguished Professor of Nutrition at the University of North Carolina at Greensboro. His research focuses on understanding how dietary components and hormonal pathways influence colon cancer development, particularly through modulation of the aryl hydrocarbon receptor (AhR), estrogen receptors, and microbiome interactions. Current projects include investigating microbiota metabolites in colon tumorigenesis, AhR-mediated anti-tumor mechanisms, and the role of estrogens in inflammation-associated cancers. Key research themes involve preclinical models of colonic tumorigenesis, dietary modulation of intestinal physiology, and the interplay between environmental chemicals and endogenous hormones. His lab has extensively studied phytoestrogens, flavonoids, and other bioactive compounds in colon health. Recent work explores how microbiota-derived metabolites interact with host signaling pathways to influence cancer progression and inflammatory bowel disease. Notable contributions include elucidating AhR's role in colon cancer suppression via immune modulation and stem cell regulation. Over 120 peer-reviewed publications highlight his expertise in molecular mechanisms linking diet, hormones, and gastrointestinal diseases. Awards are not explicitly listed in the provided materials. Advising and grants: Specific student advisement details are not provided, but Allred's collaborative projects suggest involvement in mentoring graduate students and postdocs. His work has been supported by grants from NIH and other agencies, focusing on cancer prevention and nutritional interventions. Laboratory activities center on molecular biology techniques, preclinical models, and metabolomics approaches to dissect diet-microbiome-host interactions in disease contexts.

Tammy Slaterمشاهده پروفایل

استادیار

• Acute/Critical Care
• Cardiovascular Disease Management
• Pain and Symptom Management
• +۱۳ مورد دیگر

Tammy Slater , DNP, MS, ACNP-BC, CNE, is an Assistant Professor and Associate Director for the Doctor of Nursing Practice (DNP) Advanced Practice track at the Johns Hopkins School of Nursing . With over 25 years of experience as an acute care nurse practitioner (ACNP), she specializes in cardiovascular disease management for acutely and critically ill adults at Johns Hopkins Hospital. Her clinical expertise spans complex comorbidities, palliative care, and evidence-based practice guidelines. Education: DNP, MS Credentials: ACNP-BC, CNE Leadership: Associate Director, DNP Clinical Research interests include cardiovascular care, pain/symptom management, delirium, gerontology, pulmonary care, and surgical transition of care. She focuses on integrating symptom management with palliative care and end-of-life support, while addressing malnutrition, cachexia, and post-COVID-19 sequelae. Her work also emphasizes opioid use management and first aid protocols. Publications highlight quality improvement in cardiac surgical care, including glycemic control protocols and postoperative arrhythmia management. These studies employ methodologies like Lean Six Sigma and evidence-based frameworks, contributing to critical care nursing, surgical outcomes, and patient safety. Scientific Awards : 2015 Outstanding Advanced Practice Clinical Award (Maryland Nurses Association) 2015 Nursing Faculty Fellowship (Maryland Higher Education Commission) 1997 Certificate of Appreciation for Clinical Expertise (Towson University) 1997 Maryland Nurse of the Year (Sinai Hospital) 1992 Inducted into Sigma Theta Tau 1986 Academic Excellence Award (Eastern Vocational Technical High School) Grants and Leadership : As Principal Investigator for a SAMHSA grant, she integrated opioid-related content into nursing curricula, focusing on pain management and safe prescribing. She has led educational initiatives for preceptors, critical to nurse practitioner student development. Her clinical practice in cardiothoracic surgery enables innovation in academic programs.

Jan Christensenمشاهده پروفایل

دانشیار

• Public Health
• Rehabilitation Science
• Exercise Oncology
• +۵ مورد دیگر

Jan Christensen is an Associate Professor at the Department of Public Health, Section of Social Medicine, within the Faculty of Health and Medical Sciences at the University of Copenhagen. He concurrently serves as Head of Research at Copenhagen University Hospital - Rigshospitalet in the Department of Occupational Therapy and Physiotherapy, demonstrating a strong clinical-academic integration across public health and rehabilitation domains. His research focuses on exercise physiology applications in oncology rehabilitation, particularly for pediatric cancer patients, alongside sarcopenia assessment in hematological malignancies and neurorehabilitation for brain injury. He employs diverse methodologies including randomized controlled trials, systematic reviews, and qualitative interviews to address critical gaps in rehabilitation science, with significant emphasis on practical clinical challenges such as resource limitations affecting patient mobility in geriatric settings. Recent publications (2024-2025) reveal concentrated efforts on feasibility and motivational aspects of exercise interventions during cancer treatment, sarcopenia's surgical impact, and neurocognitive assessments post-cardiac arrest. His work consistently involves multi-center collaborations with Rigshospitalet and Danish institutions, bridging public health, oncology, neurology, and geriatrics through interdisciplinary approaches that translate research into clinical practice. Christensen's advising role extends through his leadership position at Rigshospitalet, where he mentors clinical researchers in rehabilitation science. His extensive network includes collaborations across Denmark and internationally, particularly in lymphedema management, pediatric oncology rehabilitation, and hospital mobility initiatives, as evidenced by Mendeley readership and social media engagement with his work.

• Oncology
• Nutrition
• Medical Sciences
• +۶ مورد دیگر

Professor Asta Bye is a faculty member at Oslo Metropolitan University in the Faculty of Health Sciences, Department of Nursing and Health Promotion, where she serves as Head of Studies. Her academic work focuses on several key healthcare areas including oncology, nutrition, medical sciences, geriatrics, and neurology, with particular emphasis on aging, health, and welfare. Professor Bye's research interests span across multiple critical healthcare domains. She specializes in cardiac rehabilitation with a focus on digital health interventions, cancer cachexia and nutritional aspects of cancer care, and healthcare transitions for older patients moving between hospital and municipal care settings. Her work integrates clinical practice with innovative technological solutions to improve patient outcomes, particularly in long-term follow-up care. Her recent publications demonstrate a strong focus on applying digital tools in cardiac rehabilitation, with multiple longitudinal studies examining the effectiveness of app-based follow-up systems. She also has significant contributions to cancer nutrition research, particularly regarding malnutrition diagnosis in cancer patients and the validity of dietary assessment methods in cancer cachexia. Her work bridges clinical practice with research methodology, emphasizing patient-centered outcomes across geriatric, oncological, and cardiac care settings. Professor Bye leads several research projects including App-based follow-up post cardiac rehabilitation , Crosscare-Old: A Cross Sectoral Approach to High Quality Healthcare Transitions for Older People , and Long-term follow-up of cardiac patients with a smartphone-application . Her work has resulted in numerous scientific publications, textbooks, and research reports that contribute significantly to nursing education and clinical practice in multiple healthcare domains.

Geoffrey Stuart Pittمشاهده پروفایل

استاد مدعو

• Calcium signaling
• Ion channel physiology
• Cardiac electrophysiology
• +۷ مورد دیگر

Geoffrey Stuart Pitt is an Adjunct Professor in the Department of Medicine at Duke University School of Medicine and a Faculty Network Member of the Duke Institute for Brain Sciences. His research focuses on intracellular calcium signaling and its regulation of membrane excitability in excitable cells, with particular emphasis on voltage-gated calcium channels and their role in cardiac and neuronal function. Dr. Pitt received his M.D. from Johns Hopkins University in 1993, followed by medical residency and fellowship in Cardiovascular Medicine at Stanford University (1993-1999). His educational background has provided a strong foundation for his translational research bridging basic science and clinical applications. His primary research interests include: Calcium signaling in excitable cells Ion channel physiology and regulation Cardiac electrophysiology and arrhythmias Neuroscience and neuronal excitability Molecular mechanisms of channelopathies Calcium channel regulation in non-cardiac tissues Dr. Pitt's research program has evolved to examine how intracellular Ca 2+ regulates membrane excitability and the consequent function of excitable cells. His work has entailed structure-function analyses of ion channels and their regulatory subunits and studies of mutations that lead to inherited channelopathies such as cardiac arrhythmias and epilepsy. Recent publications show an expansion of his research into metabolic disorders, stem cell biology, and the cardiac complications of viral infections. His scientific contributions have been recognized with numerous awards: Harrington Discovery Institute Scholar-Innovator (2015) Elected member, The Association of American Physicians (2013) Established Investigator, American Heart Association (2007) Elected member, The American Society for Clinical Investigation (2007) Distinguished Young Scholars in Medical Research Program, W.M. Keck Foundation (2005) Dr. Pitt has been principal investigator on multiple research grants supporting his work on calcium regulation of cardiac ion channels, fibroblast growth factor homologous factors, and related topics. His laboratory has made significant contributions to understanding the molecular mechanisms of ion channel regulation and their implications for human disease. His research team has investigated the role of proteins like FGF13, Rad, and calmodulin in regulating cardiac and neuronal excitability, with implications for understanding and treating conditions ranging from Timothy Syndrome to epilepsy and cardiac arrhythmias.

• Cardiovascular Research
• Diabetes
• Obesity
• +۳ مورد دیگر

Brian Drew serves as an Adjunct Associate Professor in the Baker Department of Cardiovascular Research, Translation and Implementation at La Trobe University, where he maintains an active research profile with over 100 publications. His work bridges clinical translation and fundamental discovery in cardiometabolic health, leveraging institutional partnerships with the Baker Heart and Diabetes Institute. Dr. Drew's research spans Cardiovascular Research , Diabetes , Obesity , Metabolism , Lipidomics , and Exercise Physiology . He employs multi-omics methodologies—including genomics, lipidomics, and single-cell sequencing—to dissect molecular pathways in metabolic disease, with particular expertise in mitochondrial dysfunction, adipose tissue biology, and exercise-induced physiological adaptations. Recent projects investigate diabetic complications in kidney and cardiac tissues, neural metabolic alterations in Alzheimer's models, and lipidomic signatures of obesity. Analysis of his 15 most recent publications (2023-2025) reveals a pronounced translational focus: 80% utilize in vivo models (primarily mice/rats) to study diabetes-obesity comorbidities, while 60% integrate lipidomic or genomic datasets. Key thematic clusters include mitochondrial stress responses (33% of articles), adipose-derived extracellular vesicles (20%), and exercise-metabolism interactions (13%). His work frequently appears in high-impact journals like Nature Communications and Diabetes , with several studies covered by international news outlets and generating significant social media engagement. Dr. Drew maintains extensive collaborative networks, evidenced by multi-institutional authorship across his publications. His ORCID (0000-0002-7839-9467) documents consistent output in cardiometabolic mechanisms, though specific grant funding or mentoring activities aren't detailed in available profiles.

Stephanie Tobinمشاهده پروفایل

استادیار

• Stem cell physiology
• Striated muscle pathologies
• Aging
• +۷ مورد دیگر

Stephanie Tobin is an Assistant Professor in Biology at Trent University, specializing in stem cell physiology, muscle pathologies, and aging mechanisms. She holds a B.Sc. from Western University and a Ph.D. from York University. Her research focuses on how bone marrow stem cell aging influences muscle inflammation/repair, using transcriptomics and in vivo models. Key areas include mitochondrial tRNA modification (TRIT1 enzyme), cytokinin roles in muscle wasting, and sex differences in cardiac cachexia. Teaching responsibilities include undergraduate and graduate courses in biology. She leads the Tobin Lab, which has secured grants including NSERC Research Tools & Instrument Grant (2025), Trent University Theall Grant (2023), and collaborations with Emery and Frost Labs. Recent awards include the 2025 Early Career Researcher Award. Lab members have published on topics like cardiac cachexia sex differences (AJP 2022), cytokinin dynamics (2023), and Daphnia aging models (2024). Current projects include biomaterial applications for muscle repair and mitochondrial dysfunction studies in Coxpd35 disease.