James Petrik

James Petrik is a Part-Time Professor in the Department of Obstetrics & Gynecology within the Faculty of Health Sciences at McMaster University. His academic career spans over three decades with continuous scholarly activity from 1989 through 2025, demonstrating sustained research productivity and engagement in his field.

Dr. Petrik's research primarily focuses on ovarian cancer biology, with particular emphasis on tumor angiogenesis, the role of thrombospondin-1 in cancer progression, and the tumor microenvironment. His work explores how vascular normalization can enhance therapeutic effectiveness in ovarian cancer treatment. Additional significant research areas include reproductive toxicology, examining how substances like nicotine and cannabinoids affect reproductive function and fetal development, as well as investigating the developmental origins of health and disease.

Analysis of his most recent publications (2023-2025) reveals a continued focus on ovarian cancer mechanisms, with increasing attention to tumor metabolism, cachexia, and the intersection between cancer and cardiovascular health (cardio-oncology). His work has evolved to incorporate advanced techniques including oncolytic viral therapy, molecular targeting strategies, and detailed characterization of tumor-immune interactions. The research demonstrates a strong translational focus, with many studies utilizing sophisticated mouse models to develop potential therapeutic approaches.

Dr. Petrik maintains active collaborations across multiple disciplines, working with researchers in immunology, virology, metabolism, and cardiovascular science. His scholarly impact is evidenced by numerous publications, citations, and attention from news outlets and social media platforms as indicated in the profile metrics.