جست‌وجوی استاد و پژوهشگر

Chris Peersمشاهده پروفایل

استاد

• Physiology
• Neuroscience
• Neuropathology
• +۵ مورد دیگر

Chris Peers is a Professor of Cellular Physiology and Head of the Division of Cardiovascular and Neuronal Remodelling at the University of Leeds, UK. He holds a PhD in Pharmacology (University of London, 1988) and a B.Sc. in Physiology (University of London, 1984). His research focuses on oxygen sensing, Alzheimer’s disease, and the physiological effects of gases like carbon monoxide and hydrogen sulfide in the brain and cardiovascular systems. He has secured over £8M in research grants, including from the British Heart Foundation and Wellcome Trust. Education: Ph.D. Pharmacology, University of London (1988) B.Sc. (Hons) Physiology, University of London (1984) Research Interests: Peers’ pioneering work spans cellular physiology, with emphasis on hypoxia-induced mechanisms in neurodegenerative diseases and gas signaling in cardiovascular systems. His lab has identified novel roles for carbon monoxide in protecting against apoptosis and modulating ion channels. Collaborations with international societies highlight his leadership in arterial chemoreception research. Awards: I.S.A.C. Heymans De Castro Neil Young Scientist Prize (1988) G.L. Brown Prize Lectureship of The Physiological Society (2001) Grants & Activities: He has organized global conferences for the Physiological Society and IUPHAR, and currently serves as President-elect of the International Society for Arterial Chemoreception. His funding portfolio includes £8M+ in grants, supporting investigations into viral pathogenesis (e.g., hepatitis C) and cellular oxygen sensing pathways. Labs/Teams: Leads the Division of Cardiovascular and Neuronal Remodelling, fostering interdisciplinary research in cellular physiology and disease mechanisms.

• Membrane Trafficking
• Neurodegenerative Diseases
• Cellular Imaging
• +۳ مورد دیگر

Chiara Zurzolo is a Professor at the Institut Pasteur , where she has served since 2015. She is the Head of the Membrane Traffic and Pathogenesis Unit (2003–present) and previously directed the Cell Biology and Infection Department (2014–2019). Her academic career spans roles as Associate Professor (2000–2003) and Assistant Professor (1994–2000) at Naples University Federico II. She co-leads the Pasteur Weizmann Council (2020–present) and chairs the “Brain connectivity and Neurodegenerative Disease” thematic at Institut Pasteur (2020–present). Doctor in Medicine and Surgery (1984), Naples University PhD in Cellular and Molecular Biology (1991), Naples University Specialization in Molecular and Clinical Oncology (1992), Naples University Post-doctoral Fellow (1990–1994), Cornell University Medical School Her research focuses on membrane trafficking , protein-lipid interactions , and tunneling nanotubes (TNTs) in epithelial and neuronal cells. She investigates how TNTs facilitate the spread of pathogens like SARS-CoV-2 and misfolded proteins (e.g., alpha-synuclein, Tau) in neurodegenerative diseases (Parkinson’s, Alzheimer’s). Her work combines advanced imaging techniques and molecular biology to unravel cellular communication mechanisms. Her publications emphasize TNTs as intercellular conduits for viral transmission, protein misfolding, and lysosomal trafficking. Key themes include calcium signaling in Golgi dynamics, Wnt pathway regulation of neuronal connectivity, and astrocytic roles in alpha-synuclein degradation . Her studies bridge cell biology , neuroscience , and pathogenesis through structural and functional imaging. Radcliffe Fellow (2018–2019) EMBO Member (2015–) Hugo et Valérie Ramniceanu Prize (2011) She mentors over 50 PhD students and postdocs, serves on 30+ thesis committees, and actively secures national/international funding (ANR, ARC, INCA, EU). Her leadership roles include co-president of the Pasteur-Weizmann Council and membership in evaluation committees for scientific promotions and recruitments.

Sandra Kuhlmanمشاهده پروفایل

دانشیار

• Neuroscience
• Neural Population Analysis
• Sensory Learning
• +۵ مورد دیگر

Sandra Kuhlman, PhD, is an Associate Professor in the Department of Physiology and Biophysics at the Jacobs School of Medicine and Biomedical Sciences, University at Buffalo. Her research focuses on understanding neural mechanisms underlying sensory processing, plasticity, and circadian rhythms. Key research areas include representational drift in neural populations, visual cortex development, and the role of inhibitory circuits in cortical function. Her work employs advanced techniques such as calcium imaging and optogenetics to study how experience shapes neuronal activity patterns. Recent studies explore how visual experience influences stimulus representation quality in adult primary visual cortex, the impact of binocular deprivation on inhibitory neuron plasticity, and the molecular regulation of critical period plasticity. Dr. Kuhlman has also contributed to understanding circadian pacemaker entrainment and SCN neuron activity. Research trends in her articles emphasize cross-modal plasticity, sensory learning mechanisms, and the interplay between inhibitory circuits and cortical function. While no awards or grants are explicitly listed, her extensive publication record reflects sustained contributions to systems and computational neuroscience. No advised students or formal teams are noted in the provided materials.

Alison Dellمشاهده پروفایل

دانشیار

• Cell Signaling
• Developmental Biology
• Neuroscience
• +۳ مورد دیگر

Alison Dell is an Associate Professor in the Biology Department at St. Francis College. Her research focuses on axon guidance mechanisms in developing nervous systems and the impact of environmental pollutants on neuronal development. She holds a Ph.D. in Cell and Molecular Biology from the University of Pennsylvania, an MSc in Environmental Science and Policy from the University of Manchester, and a B.A. in Biological Sciences from Mount Holyoke College. Her interdisciplinary work bridges art and science through initiatives like Art in the Lab, co-founded in 2015 to foster collaboration between scientists and artists. Key research areas include GPCR signaling pathways in neurons and the effects of copper exposure on embryonic zebrafish development. Dell also emphasizes innovative teaching methods, including academic boot-camps to enhance student success in STEM disciplines. Publications span topics from environmental toxicology to art-science pedagogy, reflecting her dual commitment to scientific inquiry and creative expression.

Edwin Griffمشاهده پروفایل

استاد

• Olfaction
• Neuroscience
• Electrophysiology
• +۳ مورد دیگر

Edwin Griff is a Professor in the Department of Biological Sciences at the University of Cincinnati, College of Arts and Sciences. His research focuses on understanding the physiological mechanisms of sensation, particularly olfaction. He investigates how odorants stimulate olfactory receptor neurons and how these signals are processed in the olfactory bulb. His lab uses electrophysiological techniques to study mitral cell responses and neural circuits in the olfactory system. Education: PhD in Biology from Purdue University (1979), BA in Biology from Brandeis University (1970). His research spans olfactory bulb organization, spontaneous neural activity, and the effects of centrifugal inputs. He also contributed to visual system studies, examining interactions between rod photoreceptors and the retinal pigment epithelium. Grants include the University Research Council grant (2011) and NIH grant (2002–2005) on mitral cell activity. He has authored over 50 peer-reviewed publications and co-edited textbooks like PhysioEx 9.0 . He serves on departmental and university committees, including roles in undergraduate research and curriculum development. Teaching includes courses like Neurobiology, Anatomy & Physiology, and Vertebrate Sensory Biology. He emphasizes educational innovation, such as adaptive online learning systems and interactive classroom technologies.

Gianluca Galloمشاهده پروفایل

استاد

• Neuronal Development
• Axon Morphogenesis
• Mitochondrial Biology
• +۳ مورد دیگر

Gianluca Gallo is a Professor at the Lewis Katz School of Medicine, Temple University, holding joint appointments in the departments of Neural Sciences, Cancer and Cellular Biology, and the Center for Neural Development and Repair. His research focuses on neuronal development, axon branching mechanisms, and the role of mitochondria and glycolysis in axonal morphogenesis. He investigates how extracellular signals regulate the axonal cytoskeleton and axon injury responses. Education includes a PhD from the University of Illinois (1996) and postdoctoral training at the University of Minnesota (2002). Gallo has received prestigious awards such as the Leon Levy Fellowship and grants from the Alzheimer’s Association and American Heart Association. His work spans high-resolution imaging of cytoskeletal dynamics, mitochondrial function, and axonal injury mechanisms. Scientific awards include the Blas Frangione Foundation Grant (2014) and Scientist Development Grant from the American Heart Association (2013). Research highlights include uncovering PI3K signaling’s role in axonal actin patches and mitochondria-dependent mRNA translation in branch formation. His publications explore topics like axonal bioenergetics, palmitoylation in injury signaling, and the interplay between neurotrophins and cytoskeletal dynamics. Ongoing work aims to develop neuroprotective strategies for spinal cord and traumatic brain injury.

Andreas Kohlerمشاهده پروفایل

استادیار

• Medical Biochemistry
• Mitochondrial Biology
• Protein Quality Control
• +۵ مورد دیگر

Dr. Andreas Kohler is an Assistant Professor at the Department of Medical Biochemistry and Biophysics at Umeå University, Sweden. He leads the Andreas Kohler Lab , focusing on mitochondrial protein quality control (PQC) mechanisms and their roles in health, ageing, and disease. His research uses yeast ( Saccharomyces cerevisiae ) and human cell models to study mitochondrial PQC of proteins encoded by mitochondrial DNA, particularly how these processes change with age and contribute to neurodegenerative disorders like Parkinson's. Research interests include mitochondrial biology, protein folding, cellular stress response, and the interplay between mitochondrial dysfunction and ageing. His work bridges fundamental biochemistry with translational applications, aiming to identify therapeutic targets for age-related diseases. Publications from 2020-2024 highlight contributions in mitochondrial supercomplexes, prion modulation of respiratory chain defects, and multi-omic data integration using machine learning. He collaborates widely, with recent studies published in Nature Communications , Molecular Cell , and EMBO Reports . He serves as Equal Opportunities Representative for his department and actively promotes diversity in academia. His lab website ( kohler-mitolab.com ) provides further research details and outreach activities.

Lorraine Martinمشاهده پروفایل

استاد

• Cystic Fibrosis
• Chronic Obstructive Pulmonary Disease (COPD)
• Protease Research
• +۵ مورد دیگر

Lorraine Martin is a Professor of Biomolecular Sciences at Queen’s University Belfast’s School of Pharmacy. She holds a BSc and PhD in Biochemistry and a Master’s in Clinical Laboratory Medicine. Her research focuses on proteases’ roles as biomarkers and therapeutic targets in chronic airway diseases (e.g., cystic fibrosis, COPD), targeting pathways like epithelial sodium channel (ENaC) dysregulation to improve airway hydration and mucociliary clearance. She leads the Martin Group, pioneering ENaC inhibition strategies to combat disease progression. She co-founded ProAxsis Ltd., winning multiple awards including the INVENT competition (2013) and Vice Chancellor's Research Impact Prize (2016). Her €8.9M BREATH project (2017–2022) advanced COPD research capacity, earning NI Healthcare Awards (2018) and QUB Excellence in Research (2020). She holds four patents, over £11M in grants from BBSRC, MRC, and CF Trusts, and collaborates with global pharma. Her administrative roles include Programme Director for BSc Pharmaceutical Biotechnology, chairs Post-doctoral Research Oversight Group, and leads Innovation on Queen’s Gender Initiative. She advises US/Irish companies and sits on university innovation committees.

• Plant Stress Signaling
• Calcium Signaling
• Abiotic Stress Responses
• +۵ مورد دیگر

Professor Marc Knight is a faculty member in the Department of Biosciences at Durham University, specializing in plant stress signaling and calcium-mediated responses. His research focuses on how plants decode calcium signals to activate survival mechanisms under environmental stresses such as cold, drought, and heat. He has contributed significantly to understanding the role of calcium in plant immunity, stomatal regulation, and transcriptional activation. Notable areas include the interaction of synthetic molecules with GA-DELLAs to enhance growth and the decoding of calcium signatures for gene expression control. His work integrates multi-omics data with experimental approaches to study plant responses to combined abiotic stresses. Publications highlight themes like freezing tolerance via cell wall modifications, PSII stability under heat, and the role of Mediator complex subunits in stress responses. He supervises research postgraduates such as Morgan Lee and has a demonstrator, Sinthujah Vickneswaran. His email is m.r.knight@durham.ac.uk. Research interests span calcium signaling pathways, abiotic stress tolerance mechanisms, and the molecular basis of plant responses to environmental challenges. Key findings include the identification of SFR6/MED16 in cold acclimation and the role of OXI1 kinase in aphid resistance.

• Cell Biology
• Structural Biology
• Nuclear Envelope Biology
• +۴ مورد دیگر

Professor Martin W. Goldberg holds a position as Professor in the Department of Biosciences at Durham University, where he has served as Head of Electron Microscopy since 2022. His career includes roles at the Paterson Institute for Cancer Research (1995–2002) and Durham University, where he advanced from Lecturer (2002–2010) to Senior Lecturer/Associate Professor (2010–2022). His research focuses on nuclear envelope structure/function, microscopy techniques (electron and scanning), and ultra-high-resolution imaging. Education: BSc in Genetics from Leeds University (1985) PhD in Biophysics from Liverpool Polytechnic and University of California, Davis (1989) Research interests emphasize nuclear pore complexes, lamina dynamics, and advanced microscopy applications in cell biology. He pioneered methods like immunogold labeling for SEM and developed agitation modules for freeze substitution. His work bridges structural biology and disease mechanisms, including cancer cell invasiveness and progeria. Esteem indicators include invited talks at SEB and Royal Microscopical Society events, organizing conferences, and contributions to book chapters. He advises PhD students Andrea Meza-Leon, Ranjit Rai, and MSc student James Stevenson. His lab focuses on nuclear-cytoskeletal interactions and employs cutting-edge electron microscopy techniques to visualize subcellular architecture. Publications span microscopy protocols, nuclear envelope biology, and cancer research. Key work includes studies on LINC complexes in breast cancer and tardigrade heat shock proteins. His contributions advance understanding of nuclear dynamics and their roles in health and disease.

John C. Burnettمشاهده پروفایل

استاد

• Cardiovascular Medicine
• Natriuretic Peptides
• Heart Failure
• +۱۲ مورد دیگر

John C. Burnett, M.D., is a Professor of Medicine and Physiology at Mayo Clinic in Rochester, Minnesota, where he serves in the Department of Cardiovascular Medicine. He holds the Marriott Family Cardiovascular Research Professorship and is recognized as a Distinguished Investigator at Mayo Clinic. His research focuses on the endocrine function of the heart, particularly the role of natriuretic peptides in cardiorenal homeostasis, with direct applications in heart failure, hypertension, and myocardial infarction. Marriott Family Cardiovascular Research Professor, Mayo Clinic (2007–present) Distinguished Investigator, Mayo Clinic (2006) Member, American Society for Clinical Investigation (1990–present) Member, Association of American Physicians (1994–present) Dr. Burnett earned his M.D. from Loyola University Stritch School of Medicine in 1974, followed by residency and fellowship training at Mayo Clinic, including specialized training in cardiovascular disease and nephrology. He has led a continuously NIH-funded research program that has pioneered the development of designer natriuretic peptides, resulting in three novel therapeutics currently in clinical trials, seven patents, and the founding of three biotechnology companies: Nile Therapeutics, Anexon, and Zumbro Discovery. His research interests span cardiovascular medicine, natriuretic peptide biology, novel drug development, and biomarkers. His laboratory’s landmark 1986 Science paper demonstrated elevated ANP in heart failure, establishing the foundation for BNP as a diagnostic biomarker. Current work includes dual receptor-activating peptides, small molecule modulators of guanylyl cyclase, and innovative delivery platforms. The most recent 15 articles (2023–2025) reflect a strong emphasis on novel peptide therapeutics, oxidative stress modulation, genetic underpinnings of cardiomyopathy, and dual-pathway targeting in heart failure. These works highlight a trajectory toward precision medicine, multi-target therapies, and translational innovation in cardiorenal disease. National Institutes of Health (NIH) – multiple grants (1985–present) National Heart, Lung, and Blood Institute (NHLBI) – active projects on peptide therapeutics and small molecule discovery Mayo Clinic – institutional support and training programs Dr. Burnett has advised and collaborated with numerous researchers, including S.J. Sangaralingham, X. Ma, and P.M. McKie. He has held leadership roles including Director for Research at Mayo Clinic (1999–2004) and continues to chair key research committees. His work bridges basic science, translational development, and clinical application, significantly impacting the understanding and treatment of cardiorenal diseases. His laboratory has developed innovative platforms for chronic peptide delivery, including subcutaneous, gene-based, and oral systems, and continues to advance natriuretic peptide-based diagnostics and therapeutic strategies for resistant hypertension and heart failure.

Christina M. Pabelickمشاهده پروفایل

استاد

• Airway Biology
• Pediatric Lung Diseases
• Asthma Mechanisms
• +۷ مورد دیگر

Christina M. Pabelick, M.D., is a Professor of Anesthesiology and Physiology at Mayo Clinic, with appointments in the Department of Anesthesiology and Perioperative Medicine, Physiology & Biomedical Engineering, and Pediatric and Adolescent Medicine. As Vice Chair of Research in Anesthesiology, she leads interdisciplinary teams studying airway diseases, particularly asthma in children, premature infants, and aging populations. Her work focuses on cellular mechanisms regulating airway structure/function using patient-derived samples and animal models to identify therapeutic targets for lung diseases. Education: MD, magna cum laude from Heinrich-Heine University (1988); residency in Anesthesiology at Mayo Clinic (2003); Fellowships in Cardiology and Anesthesia Research. Research Interests: Asthma mechanisms, oxygen toxicity, secondhand smoke effects, neonatal lung disease, mitochondrial dysfunction, and cellular senescence. Current projects include investigating hyperoxia-induced asthma in children and oxygen therapy impacts on premature infants, funded by NIH grants such as the Hydrogen Sulfide in Neonatal Airway Disease (2023–2025). Publications: Over 160 peer-reviewed articles in journals like American Journal of Physiology and British Journal of Pharmacology , emphasizing translational physiology and novel therapeutic strategies. Awards: FAER Research Starter Grant (2004), multiple research excellence awards, and leadership roles in Sigma Xi and the American Thoracic Society.

Marina Paolucciمشاهده پروفایل

استاد

• Aquaculture
• Fish Biology
• Comparative Anatomy
• +۷ مورد دیگر

Marina Paolucci is a Full Professor ( Professore Ordinario ) in the Department of Science and Technology (DST) at the University of Sannio, Italy. Her research spans multiple disciplines within aquatic biology, environmental science, and food technology, with a particular focus on fish health, aquaculture, and natural compounds. Professor Paolucci's research interests center on aquatic organisms and their responses to environmental stressors. Her work explores polyphenol applications in aquaculture, fish reproductive physiology, water pollution monitoring through biomarkers, and natural antimicrobial compounds from plant sources. She has made significant contributions to understanding fish health assessment , crustacean nutrition , and reproductive biology in marine species including octopus and trout. Analysis of her recent publications reveals a strong focus on natural compounds for aquaculture applications , particularly polyphenols and plant extracts as feed additives. Her research demonstrates how these compounds can improve growth performance, immune response, and antioxidant status in aquatic species. She also investigates biomarkers for environmental monitoring and natural antimicrobial agents for food safety applications, showing interdisciplinary connections between aquaculture, environmental science, and food technology. Professor Paolucci has collaborated extensively with researchers across Italy and internationally, as evidenced by her numerous co-authored publications. Her work appears in journals covering aquaculture, environmental science, food technology, and marine biology, reflecting the interdisciplinary nature of her research program.

• Cardiomyopathy
• Gene Therapy
• Autophagy
• +۳ مورد دیگر

Prof. Lucie Carrier is a faculty member at the Institute of Experimental Pharmacology and Toxicology , University Medical Center Hamburg-Eppendorf. She leads a research group focused on hypertrophic cardiomyopathy (HCM), sarcomere mutations, and autophagy-lysosomal pathways. Her work bridges molecular mechanisms with translational therapies, including gene editing and pharmacological interventions. Research Interests: Cardiomyopathy pathogenesis, tubulin dynamics, iPSC disease modeling, proteotoxic stress, CRISPR/Cas9 applications, ESC consensus guidelines. Recent Publications (2024-2023): Her 2024 studies explore tubulin tyrosination in heart function and RNA editing therapies. 2023 articles investigate EGFR/IGF1R signaling and tubulin cycles, while 2022 work includes consensus documents on cardiovascular models and ACTN2 proteopathy. Scientific Awards: Recipient of European Society of Cardiology (ESC) Research Grants. Collaborations: Active in ESC Working Groups on Myocardial Function and Cellular Biology of the Heart. Her team uses iPSC-derived cardiomyocytes, mouse models, and proteomic analysis to identify therapeutic targets.

Xander Wehrensمشاهده پروفایل

استاد

• Cardiovascular Sciences
• Molecular mechanisms of cardiac arrhythmias
• Heart failure
• +۱۲ مورد دیگر

Xander Wehrens, M.D., Ph.D. is a Professor at Baylor College of Medicine with appointments in the Department of Molecular Physiology and Biophysics and the Department of Medicine (Cardiology), along with secondary roles in Neuroscience, Pediatrics (Cardiology), and Space Medicine. He holds the Juanita P. Quigley Endowed Chair in Cardiology and serves as Director of the Cardiovascular Research Institute. He has been Associate Director of the Medical Scientist Training Program (MSTP) since 2009. Dr. Wehrens earned his M.D. and Ph.D. from Maastricht University in the Netherlands in 2001 and 2002, respectively. His research is centered on the molecular basis of cardiac arrhythmias and heart failure, with a focus on intracellular calcium dynamics, ryanodine receptor (RyR2) regulation, junctophilin-2, and nucleoside-diphosphate kinase (NDPK) signaling. His lab develops novel therapeutics including small molecule inhibitors and gene therapy vectors for genome editing. His recent publications reveal a strong trend in investigating the molecular mechanisms of atrial fibrillation, particularly in post-operative and chronic kidney disease contexts, as well as inherited arrhythmias like CPVT. His work frequently employs transgenic mouse models, human iPSC-derived cardiomyocytes, and advanced molecular techniques to dissect calcium signaling and arrhythmogenesis. The integration of CRISPR/Cas9 genome editing as a therapeutic strategy is a prominent theme in his most recent research. His scientific honors include membership in the American Society for Clinical Investigation (2015) and the Association of American Physicians (2022), as well as serving on the Awards Committee of the Heart Rhythm Society (2020). Dr. Wehrens has trained over 100 students and fellows and is deeply involved in graduate education, serving as course director for advanced cardiovascular pathophysiology courses. His lab is supported by multiple NIH/NHLBI R01 grants investigating RyR2 regulation, atrial fibrillation mechanisms, junctophilin-2 cleavage, and NDPK signaling. The lab fosters collaborations, including with Dr. Stephan Lehnart at the University of Goettingen, and utilizes advanced technologies like confocal microscopy and FRET sensors.