معرفی
Dr. Andreas Kohler is an Assistant Professor at the Department of Medical Biochemistry and Biophysics at Umeå University, Sweden. He leads the Andreas Kohler Lab, focusing on mitochondrial protein quality control (PQC) mechanisms and their roles in health, ageing, and disease. His research uses yeast (Saccharomyces cerevisiae) and human cell models to study mitochondrial PQC of proteins encoded by mitochondrial DNA, particularly how these processes change with age and contribute to neurodegenerative disorders like Parkinson's.
Research interests include mitochondrial biology, protein folding, cellular stress response, and the interplay between mitochondrial dysfunction and ageing. His work bridges fundamental biochemistry with translational applications, aiming to identify therapeutic targets for age-related diseases.
Publications from 2020-2024 highlight contributions in mitochondrial supercomplexes, prion modulation of respiratory chain defects, and multi-omic data integration using machine learning. He collaborates widely, with recent studies published in Nature Communications, Molecular Cell, and EMBO Reports.
He serves as Equal Opportunities Representative for his department and actively promotes diversity in academia. His lab website (kohler-mitolab.com) provides further research details and outreach activities.
